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RISS 인기검색어
- 검색키워드
- 저자 : 최외숙(Oi-Sook Choi) (검색결과 2 건)
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최외숙(Oi-Sook Choi),권미화(Mi-Hwa Kwon),공민규(Min-Kyu Kong),이순희(Soon-Hee Lee),강성례(Sung-Rye Gang),김필순(Pil-Sun Kim),김영철(Young-Chul Kim) 환경독성보건학회 2008 환경독성보건학회지 Vol.23 No.2
The purpose of this study was to investigate the effects of frankincense oil in skin aging animal model. Skin aging was induced by both the irradiation of UVB and the application of squalene monohydroperoxide (Sq-OOH) to the back of experimental animals for 4 weeks. And at the same time experimental materials were applied topically. Six to seven weeks female SHR-1 hairless mice were divided into five groups including nor-mal (N: saline), control (C: UVB+Sq-OOH+saline), vehicle control (VC: UVB+Sq-OOH+jojoba oil), positive control (PC: UVB+Sq-OOH+0.01% retinoic acid) and experimental (E: UVB+Sq-OOH+3% Frankincense oil) groups, five animals each group. Lipid lamella and lipid content in stratum corneum of the E group were almost intact with a regular arrangement which were similar to the N group. Collagen fibers in dermis of the E group were almost intact with a regular arrangement which were similar to the N group. Relatively much less number of mast cells and inflammatory cells were found in the E group compared to the C group. The activities of XO, SOD and CAT were no significant difference between the E and N groups. In conclusion, the application of frankincense oil to the skin aging animal model reduced both the generation of free radicals and the damage of skin tissues. Therefore, frankincense oil can be used practically for the prevention or improvement of skin aging in terms of health promotion and beauty for the people.
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Hairless 마우스에서 제라늄 오일의 피부노화 억제 효과(2) -조직학적 관찰을 중심으로-
김영철 ( Young Chul Kim ),민경진 ( Kyung Jin Min ),최외숙 ( Oi Sook Choi ) 한국미용학회 2008 한국미용학회지 Vol.14 No.2
To evaluate the skin aging inhibition effect of geranium oil, skin aging animal model was produced by both the irradiation of UVB and the application of squalene-OOH to SHR-1 hairless mice for 4 weeks. And at the same time 3% of geranium oil diluted in jojoba oil was applied topically. Lipid lamella and lipid content in stratum corneum of the geranium application group were almost intact with a regular arrangement which were similar to the normal group. Collagen fibers in dermis of the geranium application group were almost intact with a regular arrangement which were similar to the normal group. Relatively much less number of mast cells and inflammatory cells were found in geranium application group compared to the control group. The activities of XO, SOD and CAT were no significant difference between the geranium oil application group and normal group. In conclusion, the application of geranium oil to the skin aging animal model reduced both the generation of free radicals and the damage of skin tissues. Therefore, geranium oil can be used practically for the prevention or improvement of skin aging in terms of health promotion and beauty for the people.
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