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최석원,한성우,심완주,최동주,김용진,유병수,황경국,전희경,신미승,유규형 대한의학회 2018 Journal of Korean medical science Vol.33 No.25
Background: We aimed to evaluate effect of heart rate (HR) reduction on left ventricular reverse remodeling (LVRR) in Korean patients with heart failure with reduced ejection fraction (HFrEF). Methods: Ambulatory patients with HFrEF, who had paired echocardiograms, N-terminal prohormone brain natriuretic peptide (NT-proBNP), and global assessment score (GAS) at baseline and 6-month (n = 157), were followed up on preset treatment schedule with bisoprolol. Results: The LVRR occurred in 49 patients (32%) at 6-month. In multivariable analysis, independent predictors associated with LVRR were use of anti-aldosterone agent (odds ratio [OR], 4.18; 95% confidence interval [CI], 1.80–9.71), young age (OR, 0.96; 95% CI, 0.92–0.99), high baseline HR (OR, 3.76; 95% CI, 1.40–10.10), and favorable baseline GAS (OR, 1.73; 95% CI, 1.06–2.81). Beneficial effect of bisoprolol, in terms of LVRR, NT-proBNP, and GAS, was remarkable in the high HR group (baseline HR ≥ 75 beats per minute [bpm]), which showed a large HR reduction. Conclusion: High baseline HR (≥ 75 bpm) showed an association with LVRR and improvement of NT-proBNP and GAS in patients with HFrEF. This seems to be due to a large HR reduction after treatments with bisoprolol. Trial registry at www.ClinicalTrials.gov, NCT00749034.
해석의 실천 ― 문천상(文天祥) 집두시(集杜詩)에 대한 고찰
최석원 한국중국어문학회 2011 中國文學 Vol.66 No.-
集句詩是中國古代詩歌上一種特殊的詩體, 取古人已成的詩句寫成別外作品, 所以大部分的文人認爲這種詩是一種文字遊戱. 集句詩在北宋時代得到發展幷且逐漸成熟. 其中王安石不盡達到了`如出一手`的藝術境地, 而且擴大了其形式範圍. 但是蘇軾, 黃庭堅等文人仍認爲集句詩是文字遊戱的一種. 文天祥的集杜詩改變了其文字遊戱的性質從而成爲了別外一種詩創作的方式, 可以認爲是歷代集句詩中最爲成功的作品. 其實文天祥與杜甫所處的相似時代背景是集杜詩創作的主要原因, 他在集杜詩總二百首上表達出宋末詩人的悲哀. 本文首先考察了文天祥集杜詩文學的特徵: 第一是主題分類, 詩人按照作品主題對整個作品進行分類, 解決了起因`集句`方式的零散; 第二是詩與文的結合, 詩人用自序的方式說明宋末特殊的社會狀況, 當時殉國的人物, 入獄的經歷等等; 第三是整個作品的相互連接貫通. 這樣, 集杜詩的文學成就是由于他對杜詩的解釋, 文天祥强調了杜詩之`詩史`的性質. 但是文天祥對詩史的解釋與以前詩史的含意有差異, 他强調杜詩的社會價値. 由此可知, 文天祥集杜詩不是對杜詩的再現, 而是用體驗的方法解釋了杜詩的現實社會上意義.
최석원,용상순,SeokWeon Choi,Sang-Soon Yong 한국우주과학회 2022 우주기술과 응용 Vol.2 No.3
Although the magnitude of the disturbance caused by the driving of the motor operated to secure the high-speed and precise directivity of the antenna is small, it acts as a major cause of impairing the image quality of the observation satellite, which requires precision directing performance. In order to acquire high-resolution image information through the improvement of the high-resolution observation satellite, proper vibration isolation and reduction design are required so that jitter generated when the directional antenna motor is driven is not transmitted to the main mission equipment. In this paper, the development process of the directional antenna vibration reduction device applied to real satellites and the effect of micro vibration reduction before and after application will be examined. This device was designed as a way to significantly improve the jitter problem by replacing only one gear in the directional antenna driving unit with a spring damper gear without any additional interface equipment. It was first applied and launched to a high-resolution earth observation satellite, and has been successfully operated so far.
Circularly Polarized Luminescence from Achiral Molecualr System
최석원 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-
Circularly polarized luminescence (CPL) is demonstrated in achiral molecular system. We prepared an achiral molecular mixture of a bent-core host and a rod-like guest blended with a fluorescent dye. CPL confirmed that the chiral superstructure consisting only of achiral molecules may serve as a chiral super space to induce chiral emission from the fluorescent dye that obeys the rod-like molecular ordering. In other words, a chiral superstructure was definitely formed by the segregated rod-like molecules embedded in the HNFs (bent-core molecules). Our results provide a novel strategy to construct dissymmetric CPL materials based on achiral molecules, which is potentially applicable for future information and display technology.