자연자원 손해배상론 : 미국 제도와의 비교 Compared with U. S. A. Institution

최미희 한국환경법학회 2001 環境法 硏究 Vol.23 No.1

식품 등의 표시기준에 대한 산업체 인식도 조사

최미희,윤수진,강은진,김건희 덕성여자대학교 열린교육연구소 2010 자연과학 논문집 Vol.16 No.-

현행 식품 등의 표시기준 개선을 위한 기초 자료를 제공하고자 표시기준에 대한 산엽체의 인식도를 조사한 결과는 다음과 같다. 국내식품의 제조, 수입, 판매 업체 22곳의 식품표시 담당자를 대상으로 설문조사를 실시한 결과, 식품 등의 표시기준에 대한 이해도가 95.5%로 높게 나타났으며 가장 이해하기 어려 운 세부 표시기준으로는 원재료명 및 함량기준 (38.5%)과 영양강조표시 (38.5%)로 나타났 다. 현행 표시기준 정책에 대한 만족도는 별로 만족하지 못함이 77.4%로 나타나 영업자 들 의 표시기준에 대한 만족도가 낮은 것으로 나타났고, 가장 불만족하는 이유로는 잦은 식품 등의 표시기준 개정으로 혼란스러움 초래 (59.3%)로 나타났다. 제조연월일 및 유통기한/품질유지기한 표시에 대해서는 응답자 중 50%가 개선해야 할 불 합리한 사항이 있다고 답했으며, 소비자의 이해도를 높이기 위하여 가장 바람직한 식품 표 시기한으로 응답자 중 61.1%가 유통기한으로 표시하는 것이 좋다고 응답하여 소비 기한 으로 표시하기를 원하는 소비자들과 다른의견 을 보였다. 또한 영양성분전면표시에 대해서 는 업체에 따라 상이한 응답을 보여주어 영양성분전면표시제 시행을 앞두고 영업자들의 의 견수렴 과정과 소비자 대상의 영양교육이 더욱 확대될 필요가 있으리라 사료된다. 방사선조사 용어에 대한 영업자들의 인식도 조사 결과 이온화 살균(40.9%)으로 용어를 개선하자는 의견이 가장 높았으며, 내포장제품의 표시기준에 대해서는 표시항목을 축소해야 한다는 의견(59.1%) 과 표시항목 축소 시 제품명(40%)과 유통기한/품질유지기한(30%)은 반드시 표시해야 한다고 응답하였다.

하천복원사업 평가기준의 과제

최미희 한국환경영향평가학회 2006 환경영향평가 Vol.15 No.1

(-201)면 산화갈륨 단결정 기판 미세 결함 분석

최미희,신윤지,조성호,정운현,정성민,배시영 한국전기전자재료학회 2022 전기전자재료학회논문지 Vol.35 No.5

Single crystal gallium oxide (Ga2O3) has been an emerging material for power semiconductor applications. However, the defect distribution of Ga2O3 substrates needs to be carefully characterized to improve crystal quality during crystal growth. We analyzed the type and the distribution of defects on commercial (-201) Ga2O3 substrates to get a basic standard prior to growing Ga2O3 crystals. Etch pit technique was employed to expose the type of defects on the Ga2O3 substrates. Synchrotron white beam X-ray topography was also utilized to observe the defect distribution by a nondestructive manner. We expect that the observation of defect distribution with three-dimensional geometry will also be useful for other crystal planes of Ga2O3 single crystals.

유아컴퓨터 활동에 대한 연구동향 분석

최미희 한국아동교육학회 2002 아동교육 Vol.11 No.1

The purpose of this study was to find out research tendency and it's characteristics of children's computer activity in recent years by analysing the actuality of research and tendency between thesis of degree and journal of children's computer activity. The targets of this study are 38 thesis of degree and 8 journal of children's computer activity that are studied by people who have majored in children's education and also presented in 1990 through 1999. The Following are the specific problems that appeared in this study. 1. How is the annual capacity of thesis of degree and journal in children's computer activity? 2. How is the tendency in the contents of research Between thesis of degree and journal? 3. How is the tendency of research methods that appeared in thesis of degree and journal? 4. How is the tendency of research targets that appeared in thesis of degree and journal? The conclusions of this study were as follows: 1. The research of children's computer activity is rapidly increasing after middle of 1990. 2. The research for children's development and the effects of computer activity is doing very actively in the tendency of overall contents of research. 3. Questionnaire, document research is shown highly in the research methods for children's computer activity. 4. For the children and document research is doing activity in the research target for chilldren's computer activity.

컴퓨터 활용수업과 구체물 활용수업이 유아의 수학적 문제 해결력 및 수학적 태도에 미치는 효과

최미희 한국아동교육학회 2004 아동교육 Vol.13 No.1

본 연구는 컴퓨터 활용수업과 구체물 활용수업에 따라 유아의 수학적 문제 해결력의 하위변인인 분류, 서열, 수, 시간, 공간, 측정에 대한 해결력 및 수학적 태도의 하위변인인 자신감, 유능감, 대안탐색에 차이가 있는지를 분석하고자 하였다. 연구문제를 검중한 결과를 토대로 다음과 같은 결론을 내릴 수 있다. 첫째, 만 5세 유아의 수학적 문제 해결력 증진에는 구체물 활용수업의 협동학습이 효과적이다. 둘째, 유아의 수학적 문제 해결력의 하위변인에서 분류, 서열, 시간, 수 개념 획득에는 구체물 활용수업 협동학습이 가장 효과적이며, 공간적 측정 개념 획득에는 컴퓨터 활용수업 협동학습이 가장 효과적이다. 셋째, 남아의 경우 구체물 활용수업 시 개별학습을 실시하는 것이 협동학습보다 더 효과적이나 여아는 차이가 없다. 넷째, 만 5세 유아의 수학적 태도 증진에는 컴퓨터 활용수업 협동학습이 가장 효과적이다. 다섯째, 유아의 수학적 태도의 하위변인에서 자신감과 유능감 향상은 컴퓨터 활용수업 협동학습이 가장 효과적이라고 할 수 있으며, 대안탐색의 향상은 구체물 활용수업 협동학습이 가장 효과적이다. The purpose of this study was to investigate five-year-old children's ability and attitude on a mathematical problem solving according to the usage of computer or concrete materials, cooperative learning or individual learning, and gender. To achieve the purpose, following research questions were established: First, is there any difference in the ability of a mathematical problem solving according to the instructional type, grouping, and gender? Second, is there any difference in the mathematical attitude according to the instructional type, grouping, and gender? Independent variables were instructional type(computer use or concrete materials use), grouping(cooperative learning or individual learning), and gender(male or female). Dependent variables were the abilities of a mathematics problem solving(classification, seriation, number concept, time, space, and measurement) and mathematical attitudes(self-confidence, perceived competence, and willingness to explorer alternatives to problems). One hundred and fifty eight of five-year-old male and female children were allocated in a group among eight group. They took mathematics classes using computer or concrete materials, cooperative or individual learning for seven times. And then, they took a communicative test to measure the ability to solve a mathematical problem, and a test to measure a mathematical attitude. Three-way analysis of covariance(ANCOVA) was used to examine research questions, and the individual analysis for each instructional type was examined if there was on interaction effect among the classes. Based on results was as follow: First, using concrete materials and performing cooperative learning is most effective to develop the ability of solving a mathematical problem for five-year-old children. Second, using concrete materials and performing cooperative learning is most effective to achieve the concept of the independent variables, classification, seriation, number concept and time, and using computer and performing cooperative learning is most effective to achieve the concept of the independent variables, space and measurement. Third, individual learning is more effective than cooperative learning in male children, but there is no difference in female children. Forth, using computer and performing cooperative learning is most effective in enhancing the mathematical attitude for five-year-old children. Fifth, using computer and performing cooperative learning is most effective in enhancing the attitude of self-confidence and perceived competence, and using concrete materials and performing cooperative learning is most effective in enhancing willingness of explore alternatives to problems.

조선궁중무용 복식 연구(I)

최미희 명지대학교 생활과학부 한복문화학회 1998 韓服文化 Vol.1 No.2

Repositioning of zoledronic acid for breast cancer using transferrin-conjugated liposome

최미희,신대환,김진석 한국약제학회 2013 Journal of Pharmaceutical Investigation Vol.43 No.6

Zoledronic acid (ZOL) is one of the most potent nitrogen containing bisphosphonates (N-BP) which are used for cancer-induced skeletal disease by inhibiting osteoclastmediated bone resorption. It acts by inhibiting the farnesyldiphosphate synthase which is one of several key enzymes in the mevalonate pathway consequently leading to osteoclast apoptosis. From recent studies, direct anti-cancer effects of bisphosphonates, particularly ZOL, was demonstrated in breast cancers. The synergic anti-cancer effects of ZOL treated with other anti-cancer agents in breast cancer cells were also reported. However, pharmacokinetic properties of ZOL have limited its cytotoxic activities because almost 60 % of injected ZOL are disposed into bone and 40 % of the dose cleared rapidly from blood, so that not enough dose of ZOL delivered to the cancer cells. For this reason, we introduced transferrin-conjugated long-circulating liposomes as targeted delivery system for enhancing the anti-cancer effect of ZOL. Transferrin receptors have been explored as a target to deliver therapeutics into cancer cells due to their increased expression on malignant cells. Liposomes were prepared by a reverse-phase evaporation vesicle method with aqueous ZOL solution. Transferrins were attached to the neutral liposomes via free thiols (–SH) to the PDP-end of the pyridylthiopropionoylamino-PEG-distearoyl-phosphatidyethanolamine (PDP-PEG-DSPE). Liposomes were characterized by measuring size distribution and zeta potential. The mean diameter of liposomes was 190 nm, and the encapsulation efficiency of ZOL was about 10 %, which was determined by HPLC analysis. Based on the 50 % inhibitory concentration (IC50) of ZOL against breast cancer cell MDA-MB-231, increased anti-cancer effect of transferrin-conjugated liposomal ZOL was evaluated compared to free ZOL and non-conjugated liposomal ZOL. In conclusion, transferrin-conjugated liposome can enhance the anti-cancer effect of ZOL and it is suggested that ZOL can be used as an anti-cancer agent with this formulation in breast cancer patients.

방사성-인산화반응을 이용한 바이오칩기반 고효율 키나아제 분석

최미희,강정애,노종국,이기택,정영진,박상현 한국방사선산업학회 2010 방사선산업학회지 Vol.4 No.2

2000년대의 자연 보전 정책 방향 : 습지 생태계를 중심으로

최미희,Choe, Mi-Hui 환경보전협회 2001 환경정보 Vol.23 No.5