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가상현실 프로그램이 뇌졸중 환자의 일상생활활동 능력에 미치는 융합적 효과 : 메타분석
최기복,조성현 한국융합학회 2020 한국융합학회논문지 Vol.11 No.8
This study was designed to test the convergence effectiveness of virtual reality programs for patients with stroke by using meta-analysis. Based on the PICOS criteria, we searched domestic literature and selected the final 9 studies in relation to ‘stroke’ and ‘virtual reality programs’. Evaluation of the risk of bias in individual studies was conducted using evaluation tools according to the design of each study. The effect size of the meta-analysis was calculated using CMA program. The mediating effect analysis was conducted by sub-group analysis and meta-regression analysis. The overall effect size of the virtual reality program on the activities of daily living ability was Hedges’s g=0.302(95% CI: 0.064∼0.540), Therefore, virtual reality programs can increase the activities of daily living in stroke patients and have a positive impact on the medical industry that the convergence of virtual reality industry and healthcare industry. 본 연구는 뇌졸중 환자를 대상으로 가상현실 프로그램에 대한 융복합적 효과를 알아보기 위해 메타분석을 실시하였다. PICOS 기준에 따라 국내 문헌을 검색하여 ‘뇌졸중’, ‘가상현실 프로그램’ 관련하여 최종 9편의 연구를 선정하였다. 개별 연구물의 비뚤림 평가는 각 연구의 설계에 따른 평가 도구를 이용하여 실시하였다. CMA 프로그램을 이용하여 메타분석의 효과크기를 산출하였다. 조절효과분석은 하위그룹분석과 메타회귀분석으로 실시하였다. 가상현실 프로그램의 일상생활활동 능력에 대한 전체 효과크기는 Hedges’s g=0.302(95% CI: 0.064∼0.540)이었다. 따라서 가상현실 프로그램은 뇌졸중 환자의 일상생활활동 능력을 증가시켜 가상현실 산업과 의료 보건 산업을 융복합한 의료산업에 긍정적인 영향을 제공할 수 있다.
제 2형 콜라겐 유도 관절염에서 수중운동과 우슬추출물이 행동반응과 관절 조직에 미치는 영향
최기복,김계엽,남기원,김경윤,김은정,Choi, Ki-Bok,Kim, Gye-Yeop,Nam, Ki-Won,Kim, Kyong-Yoon,Kim, Eun-Jung 대한물리치료학회 2009 대한물리치료학회지 Vol.21 No.2
Purpose: This study examined the effects of swimming exercise and Achyranthes Radix extracts on the inflammatory and behavioral responses in type II collagen-induced arthritic rats for 28 days. Methods: Sprague-Dawley rats were allocated randomly to one of the following four groups: only type II collageninduced (group Ⅰ), application of swimming exercise after type II collagen-induced (group II), application of Achyranthes Radix ointment after type II collagen-induced (group III), application of swimming exercise and Achyranthes Radix ointment after type II collagen-induced (group IV). Arthritis was established in SD rats by an intradermal injection of Chick type II collagen plus incomplete Freund's adjuvant at the base of the tail of the animals. The swimming exercise program consisted of a 25 min swimming session/day with a load corresponding to 5.5% of the weight bearing, three days/week for four weeks. The Achyranthes Radix ointment (0.1g) was applied twice a day for five days. The changes in behavior, H & E stain, and cyclooxygenase-2 (COX-2) level in the knee joint were assessed. Results: The gross and histological examination, after RA induction showed reddening, edema and erythema. The H & E stain revealed the destruction of articular cartilage, bony erosion and the infiltration of inflammatory cells after RA induction. The mechanical allodynia test results were significantly higher in group I than in groups II, III and IV (p<0.01). The immunohistochemistrical response of COX-2 in the knee joint showed that groups II, III, IV had a lower response effect than group I. Conclusion: Swimming exercise training and Achyranthes Radix ointment decreased the inflammatory responses and enhanced the behavioral responses in the arthritic rats.