蘇木과 그 지표물질인 brazilin이 인간 유래 각질 형성 세포의 tight junction 유전자 발현에 미치는 영향

천성혜(Seong Hye Cheon),최선경(Sun Kyung Choi),조남준(Nam Joon Cho),김기광(Kee Kwang Kim),이웅희(Woong Hee Lee),황형서(Hyung Seo Hwang),김균언(Kyoon Eon Kim),한효상(Hyosang Han) 한의병리학회 2018 동의생리병리학회지 Vol.32 No.2

발화분석 어플리케이션을 활용한 부모교육 프로그램이 자폐범주성장애 아동과 부모의 발화 개시 및 반응과 대화차례 주고받기에 미치는 영향

천성혜(Seong Hye Cheon),임동선(Dong Sun Yim) 한국언어치료학회 2016 言語治療硏究 Vol.25 No.3

Purpose : Parents’ interactive responses are important in language development of children; parents need to learn how to interact with their children. It is, however, difficult to apply at home what parents learn from parental education. Thus, the purpose of this study is to explore whether using an application that analyzes utterances increases the effects of parental education. Methods: Children between the ages of three and four with ASD and their parents particpated in the study. Pretest spontaneous speech samples were collected through parent-child interaction. Parental education sessions were then carried out once a week for ten sessions. The experimental group used an utterance analyzing application, while the control group wrote daily log. A post test collected and analyzed spontaneous speech from parent-child interactions. Results: Significant increments in parents’ number of utterances, response ratio, and number of cues were shown. Significant decreases in initiation ratio were shown. The number of utterances in parents in the experimental group decreased more than that of the control group. In the case of children, initiation in the experimental group increased, while initiation in the control group decreased. Responses in the experimental group decreased, while responses in the control group increased. The amount of turn-taking in conversations between parents and their children significantly increased. Conclusions: An application that analyzes utterances assists in increasing the effect of parental education to children with ASD and their parents’ utterances, initiation, response, and turn-taking in conversation. The use of an utterances analysis application provides feedback on the interactions between parents and children and is a helpful way to improve the effect of parental education at home.

메타 분석을 통한 언어발달장애 아동과 일반 아동의 자발화 분석 연구

임동선(Dong Sun Yim),천성혜(Seong Hye Cheon),이여진(Yeo Jin Lee),정필연(Pil Yeon Jeong) 한국언어치료학회 2015 言語治療硏究 Vol.24 No.1

Purpose: Screening is one of the most important factors for children who have communication difficulties. Using the results of the near ubiquity of smartphones in Korea, a smartphone application may be developed for screening children who have language difficulties. Therefore, spontaneous speech analysis is used to build the base of a smartphone application for future reference. The analysis of children's spontaneous speech is one of the informal assessments to evaluate their language abilities and communicative functions. The aim of meta-analysis of spontaneous speech between typical developing children and children with language impairment is to investigate the feasibility for screening language impairment. Therefore, MLU (Mean Length of Utterance), lexical diversity, and communicative function were chosen to analyze children's spontaneous speech. Methods: A systematic literature review was taken to analyze 27 studies which met the inclusive criteria by using meta-analysis (CMA2, Comprehensive Meta-Analysis-Ⅱ, 2005). A random effect model was used to analyze the differentiation of spontaneous speech between TD and LI children. Results: The results from the spontaneous speech and conversational condition indicate that children with language impairment have both lower MLU and lexical diversity than TD children. However, there is no significant different of community functions between two groups. Conclusion: MLU and lexical diversity are valuable measurements for a screening scale for children who are at risk for language impairment or delay. Moreover, MLU and lexical diversity should be included for developing a smartphone application.

스마트폰 프로그램 개발을 위한 의사소통장애 아동 부모 및 전문가 요구 분석

임동선(Dong sun Yim),김신영(Shin Young Kim),박원정(Won jeong Park),천성혜(Seong hye Cheon),이여진(Yeo Jin Lee) 한국언어청각임상학회 2014 Communication Sciences and Disorders Vol.19 No.4

배경 및 목적: 본 연구는 의사소통장애 아동의 부모 및 전문가(언어치료사)를 대상으로 '모바일 기반 의사소통 능력 증진 콘텐츠'의 요구도 및 필요성을 조사하여 언어중재 도구로서 스마트폰의 가능성을 탐색하고자 한다. 방법: 선행연구 및 기존의 검사도구, 통계청 자료를 참고하여 설문문항을 개발하고, 전문가 2인에게 문항의 타당도와 적절성을 검증받은 후 사전검사를 통하여 설문문항을 완성하였다. 대면 및 우편 발송, 온라인 참여를 통하여 설문조사를 실시하였으며, 총 189부(부모용 96부, 전문가용 93부)의 설문지가 분석 대상이 되었다. 결과: 의사소통장애 아동의 부모 96명과 언어치료사 93명, 총 189명의 연구 대상자 중 과반수가 아동의 의사소통능력 증진을 위한 스마트폰 어플리케이션 사용 경험이 있는 것으로 나타났다. 두 집단 모두 부모교육과 관련된 콘텐츠 요구도가 높았으며, 아동과의 대화 상황에서 발화의 양적인 정보에 대한 요구도는 자녀가 가진 의사소통 어려움의 종류와 무관하게 부모 집단에서 유의하게 높은 것으로 나타났다. 요구도가 높게 나타난 부모교육의 경우, 부모는 그 필요성을 높게 평가하였으나, 현재 이루어지고 있는 치료기관과 부모 간 협력은 주로 부모상담의 형식인 것으로 조사되었다. 논의 및 결론: 본 연구결과를 바탕으로 부모와 언어치료사의 실제적 요구를 반영한 스마트폰 어플리케이션을 개발하여 일상생활에서 사용할 수 있는 의사소통장애 선별 및 치료 도구로서의 가능성을 모색하는 후속 연구가 필요할 것으로 보인다. Objectives: The aim of this study is to examine the needs of parents and speech language pathologists (SLPs) when developing mobile-based contents as intervention tools for children with communication disorders. Methods: Questionnaires were developed through preceding research; assessment tools and reference data from Statistic Korea were verified by two professionals for validity and suitability. The survey was conducted in person, by mail, or online format. A total of 189 of questionnaires were chosen for analysis (96 families of children with communication disorders and 93 SLPs). Results: More than half of the 189 subjects responded that they have used smartphone applications to improve the communication skills of a child. Educational content for parents is highly desired by both parents and SLPs, while the parent group needed more quantitative information about proper utterances for themselves as conversation partners. And while parents highly desired educational material, most interactions between them and their SLPS were consultation-based. Conclusion: The results of this study suggest that a follow-up study is needed to provide communication care service via smartphone applications for speech-language intervention.

자발화 분석을 통한 만 2-5세 아동의 상호작용 기술 특성 및 언어발달지체 아동 비교 연구

임동선(Dong sun Yim),박원정(Won jeong Park),천성혜(Seong hye Cheon),이여진(Yeo Jin Lee),이지연(Ji yeon Lee) 한국언어청각임상학회 2015 Communication Sciences and Disorders Vol.20 No.3

배경 및 목적: 자발화 분석은 아동의 발화의 의미, 구문 및 화용적 특성을 드러내 주는 검사 방식으로서 언어 수준 진단에 중요한 역할을 한다. 표준화 검사만으로는 아동의 실제 언어지식을 과소평가할 수 있으며, 상호작용 기술에 대해 충분한 정보를 제공받기 어려우므로 자발화 분석이 함께 실시되어야 한다. 본 연구에서는 자발화 분석을 통해 일반 아동의 발화 수, 대화차례 개시 횟수, 반응 횟수, 대화차례 주고받기 횟수가 연령별로 어떤 양상을 나타내는지, 각각의 항목에서 일반 아동 집단과 언어발달지체 아동 집단 간에 차이가 나타나는지 알아보고자 하였다. 방법: 만 2-5세 남녀 일반 아동 및 언어발달지체 아동 131명을 대상으로, 25분간 세 가지 지정된 놀이 상황에서 자발화를 수집하고 이에 대한 상호작용 기술 분석을 실시하였다. 결과: 일반 아동 집단에서 발화 수, 반응 횟수, 대화차례 주고받기 횟수는 연령이 높아질수록 유의하게 많아지는 경향을 보였으나, 대화차례 개시 횟수에서는 유의한 차이가 나타나지 않았다. 발화 수, 대화차례 개시 횟수, 반응 횟수, 대화차례 주고받기 횟수 모두에서 일반 아동 집단과 언어발달지체 집단 간 유의한 차이가 나타났다. 논의 및 결론: 자발화 분석을 통하여 아동 상호작용 기술 발달 양상을 볼 수 있으며, 언어발달지체 아동 집단과의 유의한 차이가 있는 것으로 나타났다. Objectives: Standardized tests and spontaneous speech sample analysis have been used to measure children's language abilities. However, standardized tests alone cannot provide complete information on each child's interaction skills. To obtain specific performance on interaction skills, spontaneous speech sample analysis is essential in clinical situations. Nevertheless, there is no standardized norm in spontaneous speech sample analysis. Thus, this study is designed to investigate performance in typically developing children (TD) in different age groups by analyzing spontaneous speech samples of four subtypes (the num-ber of utterances, initiations, responses, and turn-takings), compared to those of children with language delay (LD). Methods: A total of 131 children ages 2-5 participated in this study. Spontaneous speech samples were collected during three different structured play settings of 25 minutes each and analyzed for interaction skills. Results: The results are as follows. In the TD group, the number of utterances, responses, and turn-takings increased with age, but there was no significant difference in the number of conversation initiations. There was a significant difference in the number of utterances, conversation initiations, re-sponses, and turn-takings between TD and LD. Conclusion: Results suggest that children's spontaneous speech is representative of their language development and can be an effec-tive measure in screening for children at risk of language delay.