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차재훈,남혜정,김규석,신윤진,김윤범,Cha, Jae-Hoon,Nam, Hae-Jeong,Kim, Keoo-Seok,Shin, Yoon-Jin,Kim, Yoon-Bum 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.2
Objective : Skin barrier protects skin against harmful environment. Its function includes antimicrobial barrier as well as physical barrier. But there are few studies about skin barrier function about men and women who don't have skin disease. The aim of this study is to investigate skin barrier function healthy men and women show. Method : There are many ways to measure skin barrier function, but lately transepidermal water loss is mainly used to know skin barrier function. Transepidermal water loss was measured over eight four the Korean twenties and thirties who don't have skin disease from March 14th, 2007 to March 16th 2007. We surveyed cubital fossa and cheek beside nose to measure transepidermal water loss and used vapometer. Result : After analyzed data, we concluded that cheek showed higher transepidermal water loss than cuital fossa. At cheek, the thirties had higher transepidermal water loss than the twenties. The male got higher transepidermal water loss than the female at cheek and in the average. And temperature and humidity effected on transepidermal water loss. Conclusion: In our study, it was observed that temperature and humidity effected on transepidermal water loss. In traditional korean medicine, the inbalance of cold(寒), heat(熱), dryness(燥), wetness(濕) makes many diseases and the inbalance of them induces dameum(痰飮) and the disorder of blood flow. Dameum(痰飮) and the disorder of blood flow make skin diseases made by abnormal skin barrier function in many ways. So we need to study dameum(痰飮) and the disorder of blood flow to take care of patients who have abnormal skin barrier function.
차재훈,김윤범,Cha, Jae-Hoon,Kim, Yoon-Bum 대한한방안이비인후피부과학회 2008 한방안이비인후피부과학회지 Vol.21 No.2
Objective : Skin barrier protects skin against harmful environment. Its function includes antimicrobial barrier as well as physical barrier. But there are few studies about the factors which improve skin barrier recovery after injury. The aim of this study is to investigate the factors which improve skin barrier recovery. Method : Nine hairless mice was anesthetized by inhalation and we tape stripped them. We used thermometer to know temperature one day ago, before anesthesia, before tape stripping, and after tape stripping. Vapometer was used to know transepidermal water loss before tape stripping, after tape stripping. And we used doppler flowmeter to measure blood flow before tape stripping, after tape stripping. Result : After analyzed data, we concluded that temperature was lower after anesthesia than before anesthesia and after tape stripping than before tape stripping. We could know that transepidermal water loss was lower after tape stripping than before tape stripping and more blood flowed after tape stripping. Conclusion : In our study, it was observed that temperature, transepidermal water loss, blood flow changed after tape stripping. But we thought lowered temperature was pathologic situation, more blood flow was to recover after injury. In traditional korean medicine, cold(寒) and imbalance of blood flow(血行) don't only make many skin diseases, but cold(寒) also obstructs blood flow. So we need to study how to warm cold(寒) and improve blood flow.
차재훈,김윤범,남혜정,Cha, Jae-Hoon,Kim, Yoon-Bum,Nam, Hae-Jeong 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.3
Objective : This study was to explore the change of new outpatients in ophthalmology, otolaryngology, dermatology. Methods : We did stastical analysis about 4638 new outpatients who had visited the department of ophthalmology, otolaryngology, dermatology in Kyunghee oriental medicine center from January 1, 2004 to December 31, 2006 and had ophthalmologic, otologic, rhinologic, laryngologic and dermatologic diseases. Results : The results were as follows. 1. Distribution of ophthalmology, otology, rhinology, laryngology and dermatology classification in new outpatients was 44.74% in dermatology the most, 26.50% in rhinology, 14.45% in otology, 8.78% in ophthalmology, 5.54% in laryngology. In all classifications except ophthalmology, outpatients increased, but the proportion of outpatients increased the most in dermatology. 2. The proportion of the new outpatients in ophthalmology was 20.15% in 51-60 years old the most. And 36.61% in dry eye the most, next 27.03% in visual disorder, 10.07% in strabismus. The proportion of the new outpatients in ophthalmology in strabismus decreased by 43.93 percent point but in dry eye increased by 32.17 percent point. 3. The proportion of the new outpatients in otology was 24.94% in 61+ years old the most. And 64.03% in tinnitus, hearing loss the most, next 17.46% in vertigo, dizziness. By 17.36 percent point, it in tinnitus, hearing loss decreased. But in vertigo, dizziness increased by 14.91 percent point. 4. The proportion of the new outpatients in rhinology was 40.93% in 0-10 years old the most. And it increased by 20.08 percent point. 69.30% in rhinitis the most but it decreased by 17.70 percent point. But 32.59% in sinusitis, that means it increased by 14.41 percent point. 5. The proportion of the new outpatients in laryngology was 68.09% in female, 23.35% in 51-60 years old the most. And it was 29.96% in laryngopharyngitis, 19.07% in stomatitis, 14.40% in the diseases of tongue. 6. The proportion of the new outpatients in dermatology was 37.21% in 21-30 years old the most.And it was 22.93% in atopic dermatitis the most, next 14.77% in urticaria. That means it increased by 8.19 percent point. But the proportion of the new outpatients in dermatology decreaed in acne, pruritus. Conclusions : We could know that there had been many changes of new outpatients in ophthalmology, otolaryngology, dermatology
차재훈,남혜정,김희정,박외숙,김규석,김윤범,Cha, Jae-Hoon,Nam, Hae-Jeong,Kim, Hee-Jeong,Park, Owe-Suk,Kim, Keoo-Seok,Kim, Yoon-Bum 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.3
Seborrheic dermatitis is characterized by the appearance of red, flacking, greasy lesions in regions rich in sebaceous glands. There are various opinions about the relation between seborrheic dermatitis and dandruff. Considering all available data, we consider seborrheic dermatitis and dandruff to be differing severity manifestations of similar origin. The known etiologies of seborrheic dermatitis are the abnormality of lipid and hormnes, Malassezia species, immune response. We recently focus on the relation between seborrheic dermatitis and HIV positive and AIDS patients, seborrheic dermatitis and neurological disease. The treatments of seborrheic dermatitis include topical treatments, oral treatments. There are non-specific agents, antifungal medication, corticosteroids in the topical treatments. Narrow band UVB and oral medications are known as the prophylaxis of seborrheic dermatitis but we need further study. In traditional korean medicine, the literature studies and case reports have been published. But we don't know what herbal medicine has antifungal effect against Malassezia species. So we should discriminate herbal medicines which have antifungal effect against Malassezia specieses. Then we could treat seborreic dermatitis by traditional korean medicine effectively.
Box-Behnken법을 이용한 Geobacter lovleyi 의 TCE 탈염소화 공정 최적화 연구
차재훈(Cha, Jaehun),안상우(An, Sangwoo),천석영(Chun, sukyoung),박재우(Park, Jaewoo),장순웅(Chang, Soonwoong) 한국지반환경공학회 2012 한국지반환경공학회논문집 Vol.13 No.11
본 연구는 TBOS를 기질로 적용한 Geobacter lovleyi의 TCE 탈염소화 공정에 관하여 조사하였다. Geobacter lovleiy를 이용한 TCE 탈염소화 반응은 TCE 초기농도와 Geobacter lovleyi 주입량, 초기 TBOS 농도의 독립변수를 수학적으로 표시하였고, 반응표면법(RSM)을 활용하여 모델화하였다. 이 실험들은 Box-Behnken Design(BBD)을 통해 계획된 15개의 실험을 통해 이루어졌다. RSM을 통하여 TCE 제거효율과 독립변수들의 모델식이 도출되었다 : Y1 = -11.50(initial concentration of TCE) + 4.25(단백질 양, 주입된 Geobacter lovleyi의 양) - 4.75(initial concentration of TBOS) - 6.58X1<SUP>2</SUP> - 8.583X3<SUP>2</SUP> + 93.67, Y2=-10.92X1 + 5.06X2 - 4.89X3- 4.93X3<SUP>2</SUP> - 2.19X1X<SUP>2</SUP> + 2.54X1X3 - 2.19X2X3 + 16.71. 도출된 반응모델은 수정결정계수는 각 0.975, 0.934로 1에 가깝게 나타났으며, 모델의 기여율이 높은 것으로 나타났다. 또한, 통계적 분석결과 TCE 탈염소화 효율에 미치는 영향은 TCE 초기농도 > TBOS 초기농도 > 단백질 양의 순으로 나타났으며, 상호항의 영향은 나타나지 않았다. This study investigated the use of Geobacter lovleyi with TBOS(Tetrabutoxysilane) for TCE(Trichloroethylene) dechlorination. The TCE dechlorination by Geobacter lovleiy was mathematically described as the independent variables such as initial concentration of TCE, protein mass of Geobacter lovleyi and initial concentration of TOBS, and these were modeled by the use of response surface methodology(RSM). These experiments were carried out as a Box-Behnken Design(BBD) consisting of 15 experiments. The application of RSM yielded the following equation, which is empirical relationship for the dechlorination efficiency(Y1, %) of TCE and first order kinetic constant of TCE(Y2, d<SUP>-1</SUP>) by independent variables in coded unit : Y1 = -11.50X1(initial concentration of TCE) + 4.25X2(protein mass as Geobacter lovleyi injected mass) - 4.75X3(initial concentration of TBOS) - 6.58X1<SUP>2 -</SUP> 8.58X2<SUP>2</SUP> + 93.67, Y2=-10.92X1 + 5.06X2- 4.89X3 - 4.93X3<SUP>2</SUP> - 2.19X1X2 + 2.54X1X3 - 2.19X2X3 + 16.71. In this case, the value of the adjusted determination coefficient(adjusted R<SUP>2</SUP> = 0.975 and 0.934) were closed to 1, showing a high significance of the model. Statistical results showed the order of TCE dechlorination at experimental factors to be initial TCE concentration 〉 initial TBOS concentration 〉 protein mass, but the interaction effects were non-significant.
차재훈 ( Jae Hoon Cha ),김미경 ( Mi Kyoung Kim ) 한국환경생물학회 2012 환경생물 : 환경생물학회지 Vol.30 No.2
독도 조간대 해양무척추동물의 공간적인 분포를 밝히기 위해서 2009년부터 2011년까지 10차례에 걸쳐 현장 조사를 실시하였다. Bray-Curtis 유사도를 이용한 집괴분석을 통하여 3개의 군집을 밝혔으며, 첫 번째 군집은 자갈해변군집으로 이동성 복족류인 보말고둥과 깜장각시고둥 그리고 밤고둥이 우점종으로 나타났으며, 두 번째 군집은 잔잔한 암반해안으로 보말고둥, 큰뱀고둥 그리고 군소가 우점 종으로 나타났으며, 마지막 군집은 두 종의 고착형 절지동물인 검은큰따개비와 거북손이 우점하는 것으로 나타났다. 이들 군집은 독도 암반조간대의 기질의 종류와 수리역학적인 조건에 의해 결정되었으며, 환경적인 조건이 해양생물의 생물다양성을 유지하고 증가시키는데 중요한 역할을 하는 것으로 보인다. To determine the spatial distribution of marine invertebrate communities in intertidal rocky shore on Dokdo, 10 times investigation was carried out at 7 stations during the year of 2009~~2011. The marine invertebrate community can be divided into three different groups based on cluster analysis of Bray-Curtis similarity. As a first group, the pebble beach community, Omphalius rusticus, Monodonta perplexa, and Chlorostoma lischkei which were movable gastropod with dominant occurrence. Secondly, the still rocky shore community, O. rusticus, Serpulorbis imbricatus and Aplysia kurodai occurred dominantly, Finally, the wave-exposed rocky shore community which dominantly occurred by two sessile arthropods, Barnacles, Chthamalus challengeri and Pollicipes mitella, The three groups were likely to be determined by texture of substrate and hydrodynamic conditions of rocky shore in Dokdo. The results indicated that diversity of marine intertidal invertebrate community around Dok do was mainly affected by habitat characteristics and the surrounding physical properties.
차재훈(Cha Jaehoon) 한국정치정보학회 2012 정치정보연구 Vol.15 No.1
This study aims at two major focus points of concern. First of all, it analyzes presidential agenda of four regimes from Kim Young-sam, Kim Dae-jung, Roh Moo-hyun to Lee, Myung Bak, and their policy-making processes in order to realize the agenda. It involves how to select presidential agenda, whether order of priority is considered to select agenda, and which elements and reasons are considered in selecting agenda. The second focus of study lies in exploring into the relation between policy decision process and legalization of agenda. These days, we go through some changes which all kinds of political issues and media reports propose a wide variety of challenging tasks in setting agenda. Studies on setting presidential agenda has evaluated that the president has had greater influences upon agenda of national assembly and the press. When the president gives organized concern to the pending issues and set policy priorities on them, the chances become higher that the presidential agenda would be realized with success. 본 연구는 두 가지 초점을 가지고 연구를 하고자 한다. 우선, 민주화 이후 김영삼-김대중-노무현-이명박 네 개 정권의 국정 어젠다와 이를 실현하기 위한 정책화 과정을 분석하고자 했다. 국정 어젠다를 어떻게 선택하는지 어젠다 선택의 우선 순위를 가지고 있는지 정책 어젠다를 선택하는 요소와 이유 등에 대해 살펴보고자 했다. 두 번째 연구 초점은 어젠다의 정책결정과정과 입법화 관계를 살펴보는데 있다. 어젠다 설정에서 언론보도와 각종 정치적 이슈는 과거 모델에 대해 다양한 도전적 과제를 제시하는 시대적 변화를 겪고 있다. 대통령의 어젠다 설정에 관한 연구를 볼 때 대통령은 언론과 의회의 어젠다에 더 큰 영향력을 행사하고 있다고 평가하고 있다. 현안에 대한 체계적인 관심이 기울여지고 대통령이 그 현안에 대해 정책 우선 순위를 두게 되면, 대통령의 국정 어젠다 형성과정에서 성공할 가능성이 커지게 된다.