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방사선치료 장비들의 매일 정도관리를 위한 다용도 모형의 제작
차동수,이재승,Cha, Dong-Soo,Lee, Jae-Seung 대한디지털의료영상학회 2010 대한디지털의료영상학회논문지 Vol.12 No.1
We examined the accuracy and efficiency of phantom by applying the designed phantom in order to check daily quality assurance easily by objective criteria and to confirm daily quality assurance of linear accelerator, simulator, and CT-simulator. The results of 10 weeks of linear accelerator output dose using American Association of Physicists in Medicine(AAPM) daily quality assurance guide were measured within ${\pm}1%$ of error. Mechanical check of laser alignment, optical distance indicator(ODI), CT scanner laser and alignment of gantry lasers with the center of imaging plane were measured within ${\pm}1mm$. Daily average working time for daily quality assurance of radiation therapy equipments was 38 minutes. The designed phantom was easy to install and daily quality assurance was possible with only one installation. The aspects reproducibility and efficiency as well as accuracy of quality assurance were excellent.
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차동수,Cha, Dong-Soo 대한디지털의료영상학회 2010 대한디지털의료영상학회논문지 Vol.12 No.1
High energy electron beams were to concentrically dose inside a tumor and more energy is a shape decreased of dose. Therefore, it is useful to radiation therapy of a tumor. Also high energy electron beams ionized into collision with a atom in structure material of tissue and it has big changes to dose distribution by multiple scattering. The study had to establish characteristic of electron beams from interaction of electron beams and materials. Experiment method was to measure dependence of electron beam central axis for depth dose curve, field flatness and symmetry and field size dependence. The results were able to evaluate data for a datum pint of electron beam. Also radiotherapy has to be considered for not only energy pencil of lines but characteristic, electron guide and isodose curves distribution.
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전자간증 중증환자에 있어서 혈액소치와 신생아 체중에 관한 연구
차동수,김대현,이영진,박혁,황영규 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.3
1982년 2월부터 1986년 1월까지 만 4년간 연세대학교 원주의과대학 부속 원주기독병원 산부인과에서 입원 분만한 최종 월경일이 확실한 전자간중증 환자 191명의 분만전 혈색소치 및 신생아의 출생시 체중을 비교하여 다음의 결과를 얻었다. 1. 정상임신군의 혈색소치는 11.12 gm/dl이며, 전자간중증 환자에서의 혈색소치는 10.69 gm/dl로 정상임신군보다 낮았다. 2. 임신빈혈증의 빈도는 정상임신군에서 20.4%, 전자간중증인 경우 33.5%로 정상임신군보다 높았다. 3. 전자간중증 환자에서 신생아의 태아발율지연의 빈도는 36.1%였으며, 이들의 평균 혈색소치는 11.23gm%로 다른 군들보다 높았다. 4. 전자간중증 환자에서 혈색소치가 8.0gm%이하인 경우 평균 백분위수는 34.79, 8.09.9gm%에서 34.71, 1011.9gm%에서 26.54, 12.9gm% 이상에서 23.80으로 혈색소치의 증가에 따라 신생아 체중이 점차 감소하는 경향을 보였다. 8.0gm% 이하인 군과 10.011.9gm%, 12gm% 이상의 군과 통계학적 차이가 있다. The preeclampsia severe form is one of the great tried of complications, that are responsible for the majority of maternal deaths. The causes of preeclampsia remain for the most part unknown and preeclampsia affects perinatal death, growth retardation and morbidity. This retrospective study was performed in order to find out the relationship between the hemoglobin concentration and birth weight in severe preeclampsia. This data presented here was based on the clinical records of 191 severe preeclamptic patients, whose last menstrual periods were correct, who admitted and delivered at department of Obstetrics and Gynecology, Wonju Christian Hospital, Wonju College of Medicine, Yonsei University, during 4 years from Feb. 1982 to Jan. 1986. The results were as follows : 1. Marternal hemoglobin level(10.69gm/dl) in severe preeclampsia is lower than that (11.12gm/dl)in normal pregnancy. 2. Frequency of anemia (Hb 10.0gm/dl) in severe preeclampsia(33.5%) is higher than that(20.4%) in normal pregnancy. 3. Frequency of intrauterine (Hb 10.0gm/dl) in severe preeclampsia is 36.1% and mean hemoglobin level(11.23gm%) is higher than other centile groups. 4. In severe preeclampsia, mean percentile is 34.79 in less than 8.0gm% in hemoglobin level, 34.71 in from 8,0gm% to 9.9gm% in hemoglobin level, 26.54 in from 10.0gm% to 11.9gm% in hemoglobin level and 23.80 in more than 12.0gm% in hemoglobin level. Birth weight decreased according to increased hemoglobin level.
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차동수,서을원 안동대학교 기초과학연구소 1998 基礎科學 硏究論文集 Vol.9 No.1
고온온열치료에 있어서 전극의 크기와 이에 적당한 보루스 크기는 암치료를 보다 효율적으로 행하기 위해 매우 중요함에도 불구하고 이에 대한 체계적인 연구는 거의 없는 형편이다. 이에 전극과 보루스의 최적인 모형을 제시하고저 영남대학교 의료원 방사선 종양학과에 내원한 환자를 대상으로 하여 다음과 같은 결과를 얻었다. 1. 평균 체폭과 두께는 흉부에서 29㎝, 20.6㎝, 상복부에서 28.2㎝, 20.1㎝, 골반부에서 31.5㎝, 18.3㎝으로 계측되어 30㎝ 이하의 전극이 적합한 것으로 조사되었다. 2. 15㎝, 20㎝, 25㎝과 30㎝의 전극의 크기에 각각 5㎝, 10㎝ 더 큰 보루스를 조합하여 펜텀과 인체실험을 한 결과 펜텀과 인체실험 모두에서 25㎝ 크기의 전극에 35㎝의 보루스를 복부 및 둔부에 사용하였을 경우와, 복부에 35㎝의 보루스, 둔부에 30㎝의 보루스를 사용했을 경우 온도 분포 및 환자의 내구성이 가장 좋았다. 이는 골반부위의 평균 체폭이 31㎝, 두께가 19㎝ 미만이었던 환자에게 실험체 두께의 1.5배의 전극을 사용하는 것이 가장 이상적이라는 기존의 개념에서 볼 때 28.5㎝의 전극을 쓰는 것이 가장 이상적일 것이었으나, 25㎝ 전극에서 가장 온도분포가 좋아 적어도 우리 나라 사람들의 치료에는 기존의 개념이 맞지 않음을 입증하였다. Hypothermia treatment using high temperature (38.5-43℃) has two roles for cancer treatment, which can kill tumor cell directly and can enhance the cytotoxic activity by combination with radiation therapy or chemotherapy. For both activities, electrode and bolus have essential role in depth of homeogenous heat distribution and reducing edge effect which is main obstacle for patient`s tolerance. In spite of these important role, exact data has not been established and most institutions use rough experimental data from foreign countries. Temperature distributions by hypothermia treatment are very sensitive by body fat condition, which Korean is very different from western people that means we could have big error by adoption of western data. Purposes of this study are 1) to estimate average body width and thickness at the level of thorax, upper abdomen and pelvis of Korean, 2) to estimate proper size of electrode, 3) to estimate the pattern of heat distribution by various electrode-bolus combination in phantom and 4) to decide proper electrode and bolus combination for human body. Estimated average width and thickness were 29㎝, 20.6㎝ at the thoracic level, 28.2㎝, 20.1㎝ at upper abdominal level, 31.5㎝, and 18.29㎝ at pelvic level. These data suggested that we may use lesser than 30㎝ diameter of electrode. Data from various combinations of electrodes and boluses, 25㎝ electrodes with 35cm bolus combination showed relatively good heat distribution and tolerance in patients. These data suggested that conventional concept which ideal electrode size should be 1.5 times bigger than subject`s thickness would be not correct, at least for Korean body, probably due to different body-fat distribution compare with western people. We concluded that our study may be the standard concept for hypothermia treatment in Korea and contribute to better results for cancer treatments.
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