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자궁내막종의 감별진단을 위한 난소낭종 환자의 혈청 Macrophage Migration Inhibitory Factor (MIF) 농도의 진단적 유용성에 대한 연구
김만기,김유래,홍승화,박연진,지일운,정은환,김학순,Kim, Man Ki,Kim, Yu Re,Hong, Seong Hwa,Park, Yeon Jin,Ji, IL Woon,Jeong, Eun Hwan,Kim, Hak Soon 대한생식의학회 2005 Clinical and Experimental Reproductive Medicine Vol.32 No.3
Objective: To evaluate the usefulness of serum concentrations of macrophage migration inhibitory factor (MIF) of patients with ovarian cysts for differential diagnosis of endometrioama. Method: From Jan. 2003 to Dec. 2004, preoperative serum MIF levels were assessed in 28 women with endometrioma, 32 with benign epithelial tumor, 23 with functional and simple cysts, 22 with benign mature cystic teratoma, and 25 women without ovarian tumor as control. MIF levels were determined using an ELISA (Quantikine Human MIF immunoassay, R&D Systems, Inc., USA). Results: Mean MIF levels were higher in all groups with benign tumors than control (all p<0.01), but there was no significant difference between benign tumor groups (p=0.95). There was no significant correlation between MIF levels and tumor volume, body mass index (BMI) (p=0.635, 0.674 respectively) Serum MIF level had significant correlation with count of WBC and neutrophils (p=0.008, 0.024 respectively), but had no correlation with count of lymhocytes and monocytes (p=0.688, 0.294 respectively). Conclusions: This study showed a marked increase in MIF concentrations in the peripheral blood of patients with endometrioma, but there was no significant difference with other benign tumors. Serum MIF level had significant correlation with count of WBC and neutrophils. These suggest serum MIF level has no usefulness for differential diagnosis of endometrioma from other benign ovarian cysts.
이상경 ( Sang Kyoung Lee ),홍승화 ( Seung Hwa Hong ),박연진 ( Yeon Jin Park ),지일운 ( Il Woon Ji ),정은환 ( Eun Hwan Jeong ),김학순 ( Hak Soon Kim ),김용민 ( Yong Min Kim ) 대한주산의학회 2005 Perinatology Vol.16 No.4
Cauda equina syndrome develops as rapidly progressive neurologic deficit of lower extremities and urogenital system often resulting in serious outcome such as complete irreversible paraparesis, therefore prompt diagnosis and decompression is mandatory. However, if it occurs after childbirth, it may be overlooked being regarded as symptoms related to pregnancy and delivery. We experienced a cauda equina syndrome by prolased disc in a 32-year-old woman just after Caesarian section who was managed with prompt decompressive surgery and achieved favorable result. Because of the importance of early detect and prompt decompression for cauda equina syndrome and possible occurrence at perinatal period, we report this case reviewing the literature especially concerning about changes of spine and disc during pregnancy and after delivery.
김유진 ( Yu Jin Kim ),김준우 ( Jun Woo Kim ),윤지은 ( Ji Eun Yoon ),지일운 ( Il Woon J ),이호창 ( Ho Chang Lee ),김미정 ( Mi Jung Kim ) 대한주산의학회 2010 Perinatology Vol.21 No.2
Congenital laryngeal atresia is a rare cause of airway obstruction that is almost always lethal within short period of time after birth unless diagnosed prenatally and emergency tracheostomy was performed. Other life-threatening anomalies such as tracheoesophageal fistula, gastrointestinal or urinary anomalies, and VATER syndrome are often associated with laryngeal atresia. Recently, we experienced a case of congenital laryngeal atresia with diaphragmatic hernia, ear and skull anomalies, not diagnosed prenatally, died of asphyxia due to intubation failure, and confirmed by autopsy. We report this case with a brief review of the literatures.
단일 융모막 쌍태아에서 한쪽 태아의 터너 증후군 증례 보고
장정희 ( Jeong Hui Jang ),경규상 ( Kyu Sang Kyeong ),홍덕호 ( Deok Ho Hong ),홍승화 ( Seung Hwa Hong ),지일운 ( Il Woon Ji ),정은환 ( Eun Hwan Jeong ) 대한주산의학회 2014 Perinatology Vol.25 No.4
Monochorionic twins with discordant karyotypes are rare and mostly caused by post-zygotic mitotic nondisjunction. A 32 year old nulliparous woman at 11 weeks of gestation with spontaneous twin pregnancy wasreferred to our hospital. An amniocentesis was performed in both amniotic sacs at 15 weeks of pregnancy. Onefetus in monochorionic twin pregnancy was diagnosed with Turner syndrome with cystic hygroma, and theother fetus was normal. Because of high mortality rate in abnormal fetuses, the umbilical cord coagulation wasperformed using radiofrequency ablation to prevent the damage of co-twin that may be caused by the demiseof one fetus. After delivery, chorionicity of placenta was ascertained by pathologic exam. Postnatal findings ofphysical exam, abdominal and brain sonography were normal in the surviving neonate.