第一特輯 韓國雜誌批判

조용운,이용진,김수근,곽용배,김창수 한국출판학회 1974 出版學硏究 Vol.- No.-

이슈 : 민영간병보험의 발전방향

조용운,김미화 보험연구원 2013 KIRI Weekly(주간포커스) Vol.253 No.-

인구 고령화에 따른 보험산업의 역할이 강조되고 있는 가운데 민영간병보험은 이에 부응하여 보장범위를 확대시켜 나가고 있음. 민영간병보험은 치매 및 일상생활장애상태 혹은 활동불능상태 보장은 물론 최근 노인장기요양보험의 보장대상자에게 간병비를 보장하는 상품을 개발하여 보장범위를 확대해 나가고 있음. 현재 감독자는 노후의료비보장을 위한 제도 도입을 추진하면서 간병 관련 부분을 포함시키고자 다각도로 검토하고 있음. 그러나 민영간병보험은 여러 위험요인에 직면해 있음. 노인장기요양보험의 보장대상자에 대해 보험금을 지급하는 상품은 제도변화에 따라 예상하지 못한 보험금 지급의 증가가 예상됨. 치매를 보장하는 상품은 최근 유병률이 증가추세에 있으므로 기대 밖의 보험금 지급이 예상됨. 일상생활장애상태 혹은 활동불능상태의 발생가능성도 증가하고 있음. 민영간병보험은 아직 보장이 다양하지 못하여 그 역할을 다하고 있다고 보기는 어려움. 협심증 또는 심근경색증, 뇌졸중 등은 치매에 못지않은 유병률을 보이고 있으나 주로 치매 보장에 집중되어 있고 1회성 보험금 지급이 다수를 차지하고 있음. 일상생활장애상태 혹은 활동불능상태의 경우 사실상 상당히 진척된 중증상태만을 보장하고 있음. 민영간병보험은 위험요인을 면밀히 검토하면서 보장의 다양화를 추진하는 것이 바람직하다고 봄. 노인장기요양보험의 보장대상자에 대해 보험금을 지급하는 상품은 개발에 신중해야할 것임. 치매 보장은 추세율을 보험료에 반영할 필요가 있고 시간에 따라 보험료 변경이 가능하도록 함. 뇌졸중·심장질환 등의 주요 노인성 만성질환에 대해서도 일정기간 연금형태로 보장하는 상품을 개발하는 것도 고려해 볼 만하며 이를 통해 노인장기요양보험의 급여대상자 수를 줄이는 효과를 기대할 수 있을 것임. 만성질환에 대한 보장은 1회성 지급보다는 실질적 도움을 위해 일정기간 동안 일정액으로 지급하는 상품이 적절할 것으로 봄.

Treatment of Neglected Proximal Interphalangeal Fracture Dislocation Using a Traction Device - A Case Report -

조용운,박재형,박세진,이인규,김유진 대한골절학회 2019 대한골절학회지 Vol.32 No.4

This paper reports the use of a traction device for the treatment of neglected proximal interphalangeal fracture dislocations. A 44-year-old man with a fracture dislocation of a right ring finger proximal interphalangeal joint was admitted 17 days after the injury. Closed reduction and external fixation were performed using a dynamic traction device and C-arm under a brachial plexus block. Passive range of motion exercise was started after two weeks postoperatively and active range of motion exercise was started after three weeks. The traction device was removed after five weeks. No infection occurred during the traction period. No subluxation or displacement was observed on the X-ray taken two months postoperatively. The active range of motion of the proximal interphalangeal joint was 90°. The patient was satisfied with the functional result of the treatment with the traction device. The dynamic traction device is an effective treatment for neglected fracture dislocations of the proximal interphalangeal joint of a finger.

유리체절제술과 백내장병합수술에서 후낭절개술군과 대조군의 전방깊이와 굴절력 변화

조용운,이동우,김병선,유웅선,김성재,서성욱,정인영 대한안과학회 2020 대한안과학회지 Vol.61 No.9

Purpose: To compare the effect on changes in anterior chamber depth (ACD) and refractive error between subjects after combined phacovitrectomy with posterior capsulotomy using a vitrectomy probe and control subjects after combined phacovitrectomy without posterior capsulotomy. Methods: A total of 20 eyes of 20 subjects who underwent combined phacovitrectomy with posterior capsulotomy using a vitrectomy probe were compared with 20 eyes of 20 control subjects who underwent only phacovitrectomy without posterior capsulotomy. The ACD was measured with Scheimpflug imaging (Pentacam®; OCULUS Optikgeräte GmbH, Wetzlar, Germany) before and after surgery. Also the preoperative desired refraction and postoperative refraction were compared using an auto keratorefractometor. Results: The preoperative ACD of subjects with posterior capsulotomy was 2.56 ± 0.233 mm. The ACD was 3.54 ± 0.366 mm and 3.71 ± 0.424 mm at one and three months after surgery in subjects with posterior capsulotomy. The preoperative ACD of subjects without posterior capsulotomy was 2.53 ± 0.204 mm. The ACD was 3.09 ± 0.197 mm and 2.95 ± 0.295 mm at one and three months after surgery in subjects without posterior capsulotomy. There was no significant difference between the two groups in preoperative ACD, but ACD at one and three months after surgery was significantly different between the two groups. The desired refractory error was -0.32 ± 0.124 D in subjects with posterior capsulotomy, and -0.33 ± 0.142 D in the control group. The postoperative refraction was -0.62 ± 0.132 D in patients who underwent phacovitrectomy with posterior capsulotomy, and -0.91 ± 0.292 D in the control group. There was a significant difference in refraction three months after the surgery. Conclusions: Combined phacovitrectomy with posterior capsulotomy using a vitrectomy probe may be a useful way to prevent myopic change caused by anterior migration of an intraocular lens compared with control subjects, without posterior capsulotomy, for three months after surgery. 목적: 유리체절제술과 백내장병합수술 시 유리체절단침을 이용하여 후낭절개술을 동시에 시행한 경우와 시행하지 않은 경우에 전방깊이 및 굴절력 변화를 확인하고자 하였다. 대상과 방법: 유리체절제술과 백내장병합수술 시 유리체절단침을 이용한 후낭절개술을 받은 20명 20안, 병합수술은 시행하고 후낭절개술은 시행하지 않은 환자 20명 20안을 대조군으로 선정하였다. 술 전, 술 후의 전방의 깊이는 샤임플러그 사진기(Pentacam®)를이용하였으며, 술 후 굴절력은 자동각막굴절측정기를 이용하여 예측한 굴절력과 차이를 비교하였다. 결과: 후낭절개술을 시행한 군에서 술 전 전방깊이는 2.56 ± 0.233 mm, 술 후 1개월째 3.54 ± 0.366 mm, 3개월째 3.71 ± 0.424 mm로 측정되었다. 대조군에서는 술 전 2.53 ± 0.204 mm였으며, 술 후 1개월 3.09 ± 0.197 mm, 3개월째 2.95 ± 0.295 mm로 측정되었다. 술 전 유의한 차이는 없었으며 술 후 1, 3개월째는 두 군 간에 유의한 차이가 관찰되었다. 후낭절개술은 시행한 군에서 예측굴절력은 -0.32 ± 0.124 diopters (D)였고, 술 후 3개월째 -0.62 ± 0.132 D로 측정되었으며 대조군에서는 예측 굴절력은 -0.33 ± 0.142 D였고, 술 후 3개월째 -0.91 ± 0.292 D로 측정되었고 3개월째 두 군 간에 유의한 차이가 관찰되었다. 결론: 유리체절제술과 백내장병합수술 시 유리체절단침을 이용한 후낭절개술은 술 후 3개월까지 대조군과 비교해 볼 때 근시화 및 인공수정체의 전방이동을 방지할 수 있는 방법으로 고려해 볼 수 있다.

머루주 제조

조용운,최상도,주옥수 진주산업대학교 산업과학기술연구소 1994 산업과학기술연구소보 Vol.- No.1

1993년 9월 산청군의 야산에서 생산한 머루를 대량으로 채취하여 2㎡(1×2×1m)인 발효조에 농도를 달리하여 제조한 머루주의 물성변화와 균수를 측정한 결과는 다음과 같다 1. pH는 당도와 발효기간에 영향을 받지 않았고 판형여과를 한 경우가 고형량이 적었다. 2. 발효일로부터 15일이 경과할 때 효모수는 가장 많은 1.O×10 exp (8)/㎖이었으나 그 이후 108일까지는 3.9×10 exp (7)/㎖ ~ 2.7×10 exp (7).㎖로서 그 수가 비슷하였다. 3. 20~35% 당 농도에서 농도가 짙음에 따라 효모수는 많은 경향이었으나 간균수는 특이한 경향이 없었다. Wild grape wine was processed by wild grape which produced in the mountains of Sanchung-Gun area in September 1993. It was analysis of properties of matter and a number of yeast and bacteria during the ferment. pH was not effect on sugar contents and ferment periods, and plate filter press was less to total solids than cloth filter. The heighest wild yeast when was the fifteenth day from the beginning day was 1.O×10 exp (8)/㎖, and then it was 3.O×10 exp (7) ㎖~2.7×10 exp (7)/㎖ from the 22th to the 108th day. At 20~35% of sugar contents, the yeast trended to increase more, but rod bacteria was not.

A1 Receptor-mediated Protection against Amyloid Beta-induced Injury in Human Neuroglioma Cells

조용운,정현주,김용근,우재석 대한약리학회 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.2

Adenosine has been reported to provide cytoprotection in the central nervous systems as well as myocardium by activating cell surface adenosine receptors. However, the exact target and mechanism of its action still remain controversial. The present study was performed to examine whether adenosine has a protective effect against Aβ-induced injury in neuroglial cells. The astrocyte-derived human neuroglioma cell line, A172 cells, and Aβ25~35 were employed to produce an experimental Aβ-induced glial cell injury model. Adenosine significantly prevented Aβ-induced apoptotic cell death. Studies using various nucleotide receptor agonists and antagonists suggested that the protection was mediated by A1 receptors. Adenosine attenuated Aβ-induced impairment in mitochondrial functional integrity as estimated by cellular ATP level and MTT reduction ability. In addition, adenosine prevented Aβ-induced mitochondrial permeability transition, release of cytochrome c into cytosol and subsequent activation of caspase-9. The protective effect of adenosine disappeared when cells were pretreated with 5-hydroxydecanoate, a selective blocker of the mitochondrial ATP-sensitive K+ channel. In conclusion, therefore we suggest that adenosine exerts protective effect against Aβ-induced cell death of A172 cells, and that the underlying mechanism of the protection may be attributed to preservation of mitochondrial functional integrity through opening of the mitochondrial ATP-sensitive K+ channels.

큰느타리버섯 폐배지의 물질분석과 미생물분포 연구

조용운,김홍출,김철호,민계식 진주산업대학교 산업과학기술연구소 2007 산업과학기술연구소보 Vol.- No.14

큰느타리버섯의 배양배지와 버섯수확 후 폐배지의 일반성분을 분석 하여 생육에 필요한 최적 배지 조건을 조사하고 폐배지의 미생물생균수 분포를 파악하여 폐배지의 효율적인 처리법을 알고자 하였다. 일반성분은 1) 폐배지의 경우 3개사 모두 조단백질, 조지방의 비율이 원재료 비율과 비슷하였다. 2) 조섬유에 있어서 B사는 원재료와 차이가 있었으나 A, C사는 약 1% 낮은 율로 소모되었다. 생균수의 경우는 1) 배지원 별로 생균수의 차이는 적은 경향이었다. 2) 배지용기의 상부와 하부에 있어서는 B사는 상부에 A, C사는 하부에 비슷한 생균수를 나타내었다. The purpose of this study was to examine the treatment effect of waste media after growth of Pleurotus eryngii. General nutrient analysis in waste media as followed : 1) waste media of three company were similar at protein and crude oil of low media. 2) In the case of crude fiber, B company was different at low media but A and C company were below about 1% after use. Live cell of microbioiogy as followed : 1) Live bacteria number was similar between four media. 2) B company was much at up site but A. and C company were much below site than up.

好熱性 細菌內의 Lactate Dehydrogenase에 關한 性質

趙鏞雲 진주산업대학교 1984 論文集 Vol.22 No.-

LDH효소의 安定性이 보다 높은 온도의 것을 얻기 위하여 好熱性細菌中의 活性이 높은 菌株를 自然에서 채취하여 기본성질을 조사하였다. 1. 온도에 의한 효소활성은 60℃에서 가장 높았고 30℃,80℃에서는 현저한 활성의 감소가 있었다. 2. 열안정성 : 60℃에서는 120분간 처리시까지 변화가 적었으나 70℃,80℃에서는 20분 경과시 50%이상의 효소가 실활되었다. 3. pH에 의한 영향 : pH7.6의 tris­HClbuffer solution일때가 가장 높았다. 4. pH안정성: 중성보다 ph5.8에서 가장 안정하였고 pH 5.8∼8.0사이에서는 비교적 안정하였다. 5. 균체량 : 0.5%의 glucose를 넣은 배지가 가장 량이 많았고 tryptone을 함유한 배지에서 균체량이 높게 나타났다. Heat­stable lactate dehydrogenase (LDH) was obtained from an thermophilic bacterium which selected by hot waste water or compost in Chinju area. 1. In case of LDH Crude enzyme from thermophilic bacterium. 1) Optimum temperature was at 60℃ but 30℃ and 80℃ were very decreased on enzyme activity. 2) Heat­stability: The treatment at 60℃ was non­sensitive for 120min, heat stability of crude enzyme at 70℃ and 80℃ was 50% relative activity for 20minutes. 3) Optimum pH: Enzyme activity was maximum tris­HC1 buffer in pH 7.6. 4) pH stability: pH was relatively stability at pH 5.8∼8.0 and maximum pH 5.8 at 60℃ for 3.5hours. 2. The effect of cell growth when it incubate with variety medium. Much cell was cultured media with 0.5% glucose or tryptone than That of peptone source.

신제조기술에 의한 양조간장의 물성

조용운,김홍출,갈상완 진주산업대학교 1997 산업과학기술연구소보 Vol.- No.4

We developed a new technique for manufacturing soybean sauce by a fermentor. The fermentor was sealed completely and controlled the internal gases by the pressure regulator. The fermentor was maintained at 28℃ continuously during fermentation. The changes of the contents of amino acids, organic acids, free sugars of various soybean sauces which were made from three korean food companies, two traditional korean families and an our new technique were investigated. We also checked the contents of moisture, crude fat, crude protein, crude ash and salt in these soybean sauces. On analysis of chemical composition in all samples, the contents of chemical components of our soybean sauce were moderate levels of the commercial and the traditional soybean sauces but big differences were not observed in all samples. On hydrolysis by 6N-HCI at 11O℃, 17 amino acids were detected. Especially, the contents of glutamic acid was the highest in all soybean sauces Maleic, succinic, lactic, acetic and pyroglutamic acid were identified by organic acid analysis in all soybean sauces. Maleic, succinic and lactic acid were found as major organic acids in all samples. Among free sugars, glucose, galactose, fructose, maltose and arabinose were identified. The content of galactose was the highest in the traditional soybean sauces and our product while the levels of glucose and fructose were very high in the commercial soybean sauces.

Thermus sp. Sa-15에 의한 耐熱性 Lactate Dehydrogenase의 特性

趙鏞雲,崔相道,奇宇京 진주산업대학교 농업기술연구소 1988 農業技術硏究所報 Vol.1 No.-

두엄등 비교적 자연조건이 고온으로 유지되는 곳에서 균원시료를 채취하여 열안정성의 lactate dehydrogenase를 생성하는 한 균주를 분리하였다. 선정된 균주는 고온생육의 호기성이며 gram 음성의 무포자 장간균이고 비운동성인 Thermus속이었다. 처리한 항생물질에 모두 감수성이고, 균의 생육온도는 45˚∼75℃이며 최적 생육온도는 60℃이고, lactate dehydrogenase 활성도는 생균체 g당 15.6unit이었다. 그리고 본 부분정제효소의 최적 pH는 8.0이며 최적 활성온도는 정반응이 70℃이었다. 또한 60℃에서 130분동안 처리시 안정하고 80℃에서는 20분동안 50%가 실활하였다. A bacterium which produced thermostable lactate dehydrgenase(EC 1. 1. 1. 27) was isolated from the compost. Microbiological characteristics of Thermus sp. strain was aerobic, non-motile, Gram-negative and 0.8-1.0×7-10㎛ in size and was sensitive to several antibiotics tested. Temprature range for growth of the strain was 45∼75℃, optimum was 60℃. Optimum pH for partial purified enzyme reaction was 8.0 and optimum temperature was 70℃ at pyruvate reduction. For pyruvate reduction, the enzyme was stable for 130 min. at 60℃, and its residual activity was 50% for 20 min. at 80℃.