영남문집해제 : 위재집

조상덕 영남대학교 민족문화연구소 1988 민족문화연구소 자료총서 Vol.4 No.-

일부 종합검진 수진자에서의 혈압, 혈당 및 혈중지질과 관련된 위험요인

조상덕,홍현숙,이강숙,Cho, Sang-Deog,Hong, Hyun-Sook,Lee, Kang-Sook 대한예방의학회 2000 Journal of Preventive Medicine and Public Health Vol.33 No.1

Objectives : This study was conducted to evaluate the risk factors associated with cardiovascular disease. Methods : By the questionnaire, the informations of education level, monthly income, alcohol consumption and smoking habit were obtained. Height, weight and blood Pressure(BP) were measured by a trained nurse. The level of lasting blood sugar(FBS), total cholesterol, hight-density lipoprotein(HDL) cholesterol and triglyceride were tested by enzyne method about a group of 2888 males and 1696 females ages ever 20 who had never taken the medication for hypertension. Statistical analysis, ANOVA, stepwise multiple regression, correlation analysis were peformed using SAS package program. Results : There were significant differences among age groups in systolic and diastolic blood pressure, body mass index(BMI), FBS, triglyceride and cholesterol except HDL-cholesterol. The risk factors associated with systolic and diastolic BP significantly in male were BMI, age, alcohol intake, but in female BMI, age. Smoking habit had a significant negative correlation with BP in both sex. In the group of mild hypertension ($\geq140\;mmHg\;or\geq90\;mmHg$ defined by JNC-VI) and hypertension ($\geq160\;mmHg\;or\;\geq95\;mmHg$ defined by WHO), the percent of diabetes $(FBS\geq140\;mg/dl)$, hypercholesterolemia $(\geq240mg/dl)$, and hypertriglyceridemia $(\geq200\;mg/dl)$ were significantly higher compared with normal group in male and female. BMI, and alcohol consumption had a positive correlation with FBS, total cholesterol and triglyceride. Smoking had a positive correlation with cholesterol and triglyceride but negative correlation with HDL-cholesterol in male. The educational attainment had a negative correlation with BMI, FBS, total cholesterol and triglyceride in female. Conclusions : This study suggested that drinking, smoking, and BMI and lower educational level were associated with hypertension, hyperlipidemia and diabetes, but further evaluation was needed by prospective intervention study.

담도회중증의 임상 증상과 내시경적 치료

조상덕,정성룡,유경진,유혜신,정진우,김부성 大韓消化器病學會 1986 大韓消化器病學會誌 Vol.18 No.1

드론산업의 경제적 파급효과 분석 - 산업연관분석을 중심으로 -

조상덕 ( Sang-deok Cho ),김은희 ( Eun-hee Kim ) 한국항공경영학회 2017 한국항공경영학회지 Vol.15 No.6

드론은 최근 들어 급속하게 성장하는 분야로 자연재해 관측, 농업, 물류 등 다양한 산업분야로 확장하고 있으며, 이에 맞춰 연구자들이 드론에 관한 다양한 연구를 진행하고 있지만, 아직 산업 측면에서의 연구는 시작단계에 있다. 이에 본 논문은 산업연관분석을 통하여, 현재 국내 드론산업의 성장 가능성과 파급효과를 파악하고 나아갈 방향을 제시하였다. 통계청의 표준산업분류체계와 한국은행의 산업연관표, 산업연구원의 자료를 바탕으로 드론 관련 부문을 새로운 산업으로 분류하여, 각종 유발계수를 도출하고 파급효과를 추론하였다. 연구결과 드론산업은 전방연쇄효과보다 후방연쇄효과가 크게 나타났으며, 서비스업보다 제조업에 더 의존하고 있고, 자본집약적이며, 드론산업의 종사자는 일반인보다 드론면허취득자인 연구원과 전문가가 많은 것으로 분석되었다. 드론산업의 지속적 성장을 위해 융합적 사고에 기반한 드론의 원천기술 개발, 교육기관을 통한 전문인력 양성이 필요하다는 시사점을 도출하였다. Recently, drone has been expanding to various industrial fields such as natural disasters observation, agriculture, and logistics as a fast growing industry. Although researchers are conducting researches on drones in various areas, studies with perspective of industry is still at the beginning stage. The purpose of this research is to suggest the direction of growth and the effects of the Drone industry based on the Input-output Analysis. This study classifies the drones industry, which is not classified at the national industry standard classification system and the Bank of Korea’s input-output table, into new sectors by using the data from the Korea Institute for Industrial Economics & Trade, and analyzes various effects of the Drone industry. The results of this research is as follows: 1) the backward linkage effect of the Drone industry is greater than that of the forward linkage effect, 2) the Drone industry is more dependent on the manufacturing industry than on the service industry, 3) the Drone industry is capital intensive, 4) the Drone industry intents to employ experts. Finally this study suggests the advanced drone technology development through the collaboration among researcher at the various fields, and training system for drone experts for the fast growth of the Drone industry in Korea.

The Effect of Telmisartan on Endothelial Function and Arterial Stiffness in Patients With Essential Hypertension

정안덕,박상현,박정수,조상철,홍성범,황선호,김완,김원 대한심장학회 2009 Korean Circulation Journal Vol.39 No.5

Background and Objectives: Several studies have shown that angiotensin II receptor blockers (ARBs) improve endothelial function and arterial stiffness. Telmisartan is a highly selective ARB that activates peroxisome proliferator-activated receptor γ (PPARγ). The purpose of this study was to evaluate the effects of telmisartan, such as endothelial function, arterial stiffness, and insulin sensitivity, in patients with essential hypertension. Subjects and Methods: Thirty-nine patients with essential hypertension were administered telmisartan (80 mg once daily) using an open-labeled and prospective protocol. The patients were examined before and 8 weeks after treatment to assess changes in flow mediated-vasodilation (FMD), pulse wave velocity (PWV), quantitative insulin-sensitivity check index (QUICKI), homeostasis model assessment (HOMA), and adiponection. Results: The systolic and diastolic blood pressure (BP) decreased from 153±15 mmHg and 90±13 mmHg to 137±16 mmHg and 84±10 mmHg after telmisartan treatment, respectively (p<0.01). Telmisartan therapy increased the FMD from 7.6±3.5 to 9.0±2.8% (p<0.01). The following parameters of arterial stiffness were significantly improved after telmisartan therapy: brachial-ankle pulse wave velocity (baPWV), from 17.2±3.1 to 15.9±2.6 m/ sec; heart-carotid PWV (hcPWV), from 9.7±1.8 to 9.0±1.9 m/sec; and heart-femoral PWV (hfPWV), from 11.3±1.9 to 10.7±1.9 m/sec (p<0.01). There were no changes in QUICKI, the HOMA level, and plasma adiponectin (p=NS). Conclusion: These results suggest that telmisartan is effective in improving endothelial function and arterial stiffness in patients with essential hypertension. Background and Objectives: Several studies have shown that angiotensin II receptor blockers (ARBs) improve endothelial function and arterial stiffness. Telmisartan is a highly selective ARB that activates peroxisome proliferator-activated receptor γ (PPARγ). The purpose of this study was to evaluate the effects of telmisartan, such as endothelial function, arterial stiffness, and insulin sensitivity, in patients with essential hypertension. Subjects and Methods: Thirty-nine patients with essential hypertension were administered telmisartan (80 mg once daily) using an open-labeled and prospective protocol. The patients were examined before and 8 weeks after treatment to assess changes in flow mediated-vasodilation (FMD), pulse wave velocity (PWV), quantitative insulin-sensitivity check index (QUICKI), homeostasis model assessment (HOMA), and adiponection. Results: The systolic and diastolic blood pressure (BP) decreased from 153±15 mmHg and 90±13 mmHg to 137±16 mmHg and 84±10 mmHg after telmisartan treatment, respectively (p<0.01). Telmisartan therapy increased the FMD from 7.6±3.5 to 9.0±2.8% (p<0.01). The following parameters of arterial stiffness were significantly improved after telmisartan therapy: brachial-ankle pulse wave velocity (baPWV), from 17.2±3.1 to 15.9±2.6 m/ sec; heart-carotid PWV (hcPWV), from 9.7±1.8 to 9.0±1.9 m/sec; and heart-femoral PWV (hfPWV), from 11.3±1.9 to 10.7±1.9 m/sec (p<0.01). There were no changes in QUICKI, the HOMA level, and plasma adiponectin (p=NS). Conclusion: These results suggest that telmisartan is effective in improving endothelial function and arterial stiffness in patients with essential hypertension.

40세 이하의 한국인에서 발생한 급성 심근경색증의 임상적 특성

조상철 ( Sang Cheol Cho ),정명호 ( Myung Ho Jeong ),김원 ( Weon Kim ),최옥자 ( Ok Ja Choi ),정안덕 ( An Doc Chung ),강원유 ( Won Yu Kang ),조용찬 ( Yong Chan Cho ),안영근 ( Young Keun Ahn ),김완 ( Wan Kim ) 대한내과학회 2008 대한내과학회지 Vol.74 No.5

목적: 우리나라에서 연령에 따른 급성심근경색증 환자의 동맥경화 위험인자와 기본적 특성, 관상동맥 조영술 소견 및 주요 심장사건 등에 대해 직접적으로 비교한 결과는 많지 않다. 방법: 1997년 6월부터 2006년 2월까지 급성심근경색증으로 관상동맥 조영술을 실시한 환자 중 연령이 40세 미만인 환자 108명을 I 군으로 하였고, 이와 비교된 70세 이상 환자 64명을 II 군으로 하였다. 기본 임상적 특성, 심장초음파, 관상동맥 조영술 및 주요 심장사건 발생 등에 관하여 비교분석 하였다. 주요심장사건은 사망, 표적혈관의 재협착, 급성심근경색증의 재발과 관상동맥 우회술 시행 등으로 정의하였다. 결과: 1) 두 군 모두에서 남성의 빈도가(I군 vs. II군: 94.6% vs. 56.1%) 많았으며, 특히 I 군에서 더 많았다(p<0.001). 2) 동맥경화의 위험인자는 I 군에서 흡연(78.7 vs. 46.9%, p<0.001)과 고지혈증(45.4 vs. 14.1%, p<0.001)이 많았고, II군에서 고혈압(23.1 vs. 40.6%, p=0.01)과 당뇨병(11.6 vs. 34.4%, p<0.001)이 많았다. 3) 심초음파의 좌심실 구혈율은 I군에서 높았다(55.1±14.1% vs. 50.5±14.1%, p=0.042). 4) 혈중 고감도 C반응단백(1.7±2.6 vs. 3.4±4.4 mg/L, p=0.015)과 homocysteine (11.5±7.0 vs. 15.3±9.7 μmol/L, p=0.029) 은 II 군에서 더 높았다. 5) 관상동맥 조영술에서 표적혈관의 경우 II군에서 우관상동맥이 높은 빈도를 보였으며(35.2% vs. 50.0%, p=0.021), 병변 형태의 분류에서 유의한 차이는 없었다. 병변혈관 수에서 단일혈관 질환이 I 군에서 많았으며 (78.7% vs. 59.4%, p=0.007), 시술 전 Thrombolysis in Myocardial Infarction (TIMI) 혈류등급은 I 군에서 grade II-III (58.3% vs. 42.2%, p=0.040)의 빈도가 높아 더 좋은 혈류등급을 보였다. 6) 86.6%의 환자에서 평균 2.5년의 임상추적이 이루어졌으며, 심장사망은 II 군에서 높았으나(2.1% vs. 15.1%, p=0.002), 전체 주요 심장사건 발생률은 양군 사이에 차이는 없었다. 결론: 한국에서 40세 이하에 발생한 급성심근경색증 환자는 남성, 흡연 및 고지혈증 등의 위험인자를 가지고 있었으며, 관상동맥 조영술에서 단일혈관 질환이 많았고, 추적관찰 결과 고령의 환자에 비해 심인성 사망은 적었다. Background/Aims: It is known that mortality increases with age for patients who suffer with acute myocardial infarction (AMI). Yet there isn`t much data on the clinical characteristics and long-term prognosis of young patients with AMI. Methods: We analyzed two groups of patients with AMI who underwent coronary angiogram: 108 patients younger than 40 years as group I and 64 patients over 70 years old as group II. We compared the baseline clinical characteristics, the echocardiographic and coronary angiographic findings, and the major adverse cardiac event (MACE). Results: Male gender (94.4% vs. 56.1%, respectively, p<0.001), smoking (78.7% vs. 46.9%, respectively, p<0.001) and hyperlipidemia (45.4% vs. 14.1%, respectively, p<0.001) were more frequent in group I, whereas hypertension (23.1% vs. 40.6%, respectively, p=0.015) and diabetes (11.6% vs. 34.4%, respectively, p<0.001) were more common in group II. The left ventricular ejection fraction (55.1±12.2% vs. 50.5±14.1%, respectively, p=0.042) was higher in group I. The serum levels of high sensitivity C-reactive protein (1.7±2.6 vs. 3.4±4.4 mg/L, respectively, p=0.015) and homocysteine (11.5±7.0 vs. 15.3±9.7 μg/L, respectively, p=0.029) were higher in group II. One vessel disease (78.7% vs. 59.4%, respectively, p=0.007) and good Thrombolysis In Myocardial Infarction (TIMI) flow (TIMI II-III, 58.3% vs. 41.2%, respectively, p=0.040) were more common in group 1. There were no differences between the two groups for the development of MACE during the 28±21 months of clinical follow-up, but cardiac death was lower in group I than in group II (2.1% vs. 15.4%, respectively, p=0.002). Conclusions: Male gender, smoking and hyperlipidemia were the major risk factors of Korean young AMI patients. In addition, single vessel disease and good TIMI flow were more frequent and cardiac death was less frequent in the younger AMI patients.(Korean J Med 74:515-522, 2008)

Telmisartan Improves Endothelial Function and Arterial Stifness in Metabolic Syndrome Patients

정안덕,김완,박상현,박정수,조상철,강원유,조용찬,황선호,김원 한국지질동맥경화학회(구 한국지질학회) 2007 한국지질동맥경화학회 추계학술발표논문집 Vol.2007 No.-

양성 충수돌기궤양에서 발생한 급성 하부위장관출혈 1예

조상철,서영호,박정수,박상현,정안덕,이봉규,주소영,이남훈,송근영,송성환,이인경,고향미 대한소화기내시경학회 2008 Clinical Endoscopy Vol.36 No.3

급성 하부위장관출혈의 원인은 치질이 가장 흔하며, 그 외에 게실증, 혈관형성이상, 허혈결장염 등이 있으나, 충수돌기가 원인이 되는 경우는 드물다. 저자들은 신선혈변을 주소로 내원한 33세 여자 환자의 대장내시경에서 충수돌기의 출혈을 확인한 후 수술을 통해 얻은 조직검사에서 충수돌기의 양성궤양이 진단된 1예를 경험하였기에 문헌고찰과 함께 보고한다.

Poster : Effects of Telmisartan and Rosuvastatin for Endothelial Function and Arterial Stiffness in Patients with Essential Hypertension

홍명주,정안덕,김원,김종범,김승주,박상현,박정수,조상철,황선호,김완 한국지질동맥경화학회(구 한국지질학회) 2008 한국지질동맥경화학회 추계학술발표논문집 Vol.2008 No.-

구연 : 순환기 ; 베트남 참전 고엽제 환자의 심혈관 질환 발생에 대한 후향적 연구

강원유,김한균,조상철,정안덕,조용찬,기영화,이봉규,황선호,류형선,김완 대한내과학회 2005 대한내과학회 추계학술대회 Vol.69 No.10