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치주 지지가 감소된 소구치에서 포스트가 치근 응력 분포에 미치는 영향에 대한 3차원 유한요소법적 연구
정혜진,유재흥,오남식,김한성,Jeong, Hye-Jin,Yoo, Jae-Heung,Oh, Nam-Sik,Kim, Han-Sung 대한치과보철학회 2007 대한치과보철학회지 Vol.45 No.5
Statement of problem: The endodontically treated tooth is generally restored with post and core, owing to the brittle and the loss of large amount of tooth structure. As periodontal treatment was developed, there are many cases that periodontally involved teeth used in prosthetic treatment. Purpose: The purpose of this study was to analyze the stress distribution in the dentin and post structures by the various post materials and the amount of remaining alveolar bone height. Material and method: The 3-dimensional finite element models of mandible 1st premolars were divided into six types according to the various amount of remaining alveolar bone and post type. All types were modeled using equal length, diameter and shape of the post. Three types of post and core materials were used: prefabricated titaniumpost and amalgam core, prefabricated stainless steel post and amalgam core, and cast gold post and core. 300 Newton force was applied to functional cusp of mandible 1st premolar. Results: The results were as follows: First, there was no apparent difference in the pattern of stress distribution according to the alveolar bone condition concentrate on the post middle area. Second, there was difference in pattern of stress distribution according to the core materials, gold post and core generated same than amalgam core. Third, there was no apparent difference in the pattern of stress distribution within the dentin according to the post and core materials. But a cast gold post and core generated the lowest maximum stress value, a stainless steel post generated the highest maximum stress value. Fourth, in the reduced alveolar bone model, maximum stress value is 1.5 times than that of the normal alveolar bone model. Conclusion: Within the limitations of this study, to provide minimal stress to the root with alveolar bone reduced, the post length may be as long as apical seal was not destroyed. To prevent fracture of tooth, it is rational to use gold alloy which material was good for stress distribution for post materials.
자궁경부의 염증 및 종양병변에서 Epstein-Barr 바이러스의 검출
정혜진,이응석,림정화,박설희,강재성,김인선,Jeong, Hye-Jin,Lee, Eung-Seok,Lin, Zhen-Hua,Park, Seol-Hee,Kang, Jae-Sung,Kim, In-Sun 대한세포병리학회 2001 대한세포병리학회지 Vol.12 No.2
The prevalence of Epstein-Barr virus(EBV) in the uterine cervix was investigated to define the possible etiologic role in cervical carcinogenesis. The viral genotyping and LMP-1 30bp deletion were also stooled. The materials included 169 uterine cervical swabs(152 within normal limits, 12 atypical squamous cells of uncertain significance, 3 low grade intraepithelial lesions, and 2 high grade squamous intraepithelial lesion) and 104 uterine cervical tissues obtained from hysterectomy specimens(32 carcinoma in situ, 9 microinvasive squamous cell carcinomas, 37 invasive squamous cell carcinomas, 7 adenocarcinomas, 7 adenosquamous carcinomas, and 12 cervicitis). EBV detected by PCR for EBNA-1 was positive in 52(56.5%) of 92 invasive and noninvasive cervical carcinomas, and 80(48.8%) of 164 inflammatory or normal cervices. The viruses detected in carcinomas were all type A, and LMP-1 30bp deletion form was more frequent in premalignant and malignant cervical lesions than in nonneoplastic cervices. From the above results, it may be concluded that EBV is one of common viruses detected in uterine cervix of Korean women, and type A virus and LMP-1 30bp deletion form may have a role in cervical carcinogenesis.
정혜진,김용성,Jeong, Hye-Jin,Kim, Yong-Sung 한국정보처리학회 2009 정보처리학회논문지B Vol.16 No.1
보다 효과적인 색인어 추출 및 색인어 가중치 결정을 위하여 문서의 내용뿐 아니라 구조를 이용하여 색인을 추출하는 연구가 이루어지고 있는데, 대부분의 연구들이 XML 태그의 중요도가 아닌, 문맥상의 단락에 대한 중요도를 계산하는게 일반적이다. 이러한 기존 연구들은 대부분이 객관적인 실험을 통해서 중요도를 입증하기보다는 상식적인 관점에서 단순한 수치로 중요도를 결정하고 있다. 본 논문에서는 웹 문서 관리를 위한 표준으로 자리잡아가고 있는 XML 문서의 태그 정보를 이용한 자동색인을 위하여, 논문을 구성하는 주요 태그를 중요도에 따라 분류하고, 낮은 태그에서 추출된 용어 가중치를 계산하고, 그 가중치로 높은 가중치의 태그에서 추출된 용어의 가중치를 갱신해 가면서 최종 가중치를 계산하는 방법을 제안한다. 보다 객관적인 가중치 결정을 위하여 사용자가 중요하게 생각하는 태그를 실험해 보고 그에 따라 중요도를 분류하여 가중치 계산에 반영한다. 그리고 기존 태그 중요도 결정 방법을 적용하여 계산된 색인어 가중치를 이용한 검색성능과 비교함으로써 본 논문에서 제안한 방법을 적용하여 계산된 색인어 가중치의 효과를 검증한다. For more effective index extraction and index weight determination, studies of extracting indices are carried out by using document content as well as structure. However, most of studies are concentrating in calculating the importance of context rather than that of XML tag. These conventional studies determine its importance from the aspect of common sense rather than verifying that through an objective experiment. This paper, for the automatic indexing by using the tag information of XML document that has taken its place as the standard for web document management, classifies major tags of constructing a paper according to its importance and calculates the term weight extracted from the tag of low weight. By using the weight obtained, this paper proposes a method of calculating the final weight while updating the term weight extracted from the tag of high weight. In order to determine more objective weight, this paper tests the tag that user considers as important and reflects it in calculating the weight by classifying its importance according to the result. Then by comparing with the search performance while using the index weight calculated by applying a method of determining existing tag importance, it verifies effectiveness of the index weight calculated by applying the method proposed in this paper.
유전자 알고리즘을 이용한 Passive Star 네트워크의 가상위상설계
정혜진,위규범,예홍진,홍만표,Jeong, Hye-Jin,Wi, Gyu-Beom,Ye, Hong-Jin,Hong, Man-Pyo 한국정보처리학회 2000 정보처리논문지 Vol.7 No.3
We can consider the interconnection structure suing WDM from two different levels, physical and virtual topologies. In the virtual topology, various channels on physical links can be established between transmitters and the receivers of the nodes. It is important to design efficient virtual topologies, because they have a benefit of performance improvement in interconnection networks depending on traffic matrices without changing physical topologies. In this paper we suggest a way to design virtual topologies that minimize average packet delays for given traffic matrices using genetic algorithms.
오라클 VPD 기반의 RDF 웹 온톨로지 접근 제어 모델의 설계 및 구현
정혜진,정동원,Jeong, Hye-Jin,Jeong, Dong-Won 한국시뮬레이션학회 2008 한국시뮬레이션학회 논문지 Vol.17 No.3
이 논문에서는 웹 온톨로지를 위한 오라클 보안 모델 기반의 구현 모델을 제안한다. 최근 웹 온톨로지에 대한 접근 제어를 위해 관계형 데이터베이스 보안 모델을 이용한 접근 제어 모델이 개발되고 있으며 대표적인 접근제어 모델이 RAC 보안 모델이다. 그러나 RAC 보안 모델은 관계형 데이터베이스의 표준 보안 모델에 기반을 두고 있으며 실제 관계형 데이터베이스 관리시스템의 구현 모델은 개발되어 있지 않다. 이 논문에서는 이러한 RAC 보안 모델의 문제점을 해결하기 위하여 현재 가장 널리 사용되며 다양한 보안 정책을 제공하는 RDBMS인 오라클 기반의 구현 모델을 제안한다. 또한, 제안하는 RAC 구현 모델의 구현 및 평가에 대하여 기술한다. 특히, 제안하는 구현 모델은 오라클에서 제공하는 VPD 보안 모델을 이용하며 높은 실용성과 활용성을 제공한다. This paper proposes a new implementational model based on the security model of Oracle for Web ontology. Recently, several access control models using relational database security model for access control to Web ontology have been developing, and one of the most representative access control model is the RAC model. However, the RAC model is based on the standard security model, and thus it does not provide a implementational model for practical relational database management systems. In this paper, we propose an implementational model based on Oracle which is widely used and providing various security policies. This paper shows the implementation and experimental evaluation. Especially, the proposed model uses the VPD security model of Oracle and support high application and usability.
조직별 및 나이에 따른 마이토콘드리아 DNA 결손 (${\Delta}mtDNA^{4977}$)의 축적
정혜진,정형민,조성원,김현아,이경술,권황,최동희,곽인평,윤태기,이숙환,Jeong, Hye-Jin,Chung, Hyung-Min,Cho, Sung-Won,Kim, Hyun-Ah,Lee, Kyung-Sool,Kwon, Hwang,Choi, Dong-Hee,Kwak, In-Pyung,Yoon, Tae-Ki,Lee, Sook-Hwan 대한생식의학회 2003 Clinical and Experimental Reproductive Medicine Vol.30 No.3
Objectives: Controversial arguments exists on both the case for and against on the accumulation of mitochondrial DNA (mtDNA) deletion in association to tissue and age. The debate continues as to whether this mutation is a major contributor to the phenotypic expression of aging and common degenerative diseases or simply a clinical insignificant epiphenomenon. The objective of this study was to determine whether the accumulation of mtDNA deletion is correlated with age-related and tissue-specific variation. Materials and Methods: One hundred and fifty-seven tissues from blood, ovary, uterine muscle, and abdominal muscle were obtained from patients ranging in age from 31$\sim$60 years. After reviewing the clinical reports, patients with mitochondrial disorder were excluded from this study. The tissues were obtained at gynecological surgeries with the consent of the patient. Total DNA isolated from blood, ovary, uterine muscle, and abdominal muscle was amplified by two rounds of PCR using two pairs of primers corresponding to positions 8225-8247 (sense), 13551-13574 (antisense) for the area around deleted mtDNA and 8421-8440 (sense), 13520-13501 (antisense) for nested PCR product. A statistical analysis was performed by $x^2$-test. Results: About 0% of blood, 94.8% of ovary, 71.4% of uterine muscle, and 86.1% abdominal muscle harbored mtDNA deletion. When we examined the proportion of deleted mtDNA according to age deletion rate was 90% of ovary, 63.6% of uterine muscle, 77.7% of abdominal muscle in thirties and 100% of all tissue in fifties. Conclusion: The findings of this study suggest that the mtDNA deletion is varied in tissue-specific pattern and increases with aging.
강황 열수 추출물의 항산화 활성 및 C2C12 Myoblasts의 산화적 손상에 대한 보호 효과
정혜진(Hye-Jin Jeong),김신태(Shintae Kim),박정진(Jeongjin Park),김기홍(Ki Hong Kim),김경미(Kyungmi Kim),전우진(Woojin Jun) 한국식품영양과학회 2017 한국식품영양과학회지 Vol.46 No.11
본 연구에서는 강황 열수 추출물의 항산화 활성 및 산화적 스트레스에 대한 보호 효과를 확인하고자 하였다. 항산화 활성을 확인하기 위해 총 페놀성 화합물 함량, 총 플라보노이드 함량 및 라디칼 소거능을 측정하였다. 강황 열수 추출물의 총 페놀성 화합물 및 플라보노이드 함량은 각각 2,474.4±31.9 mg GAE/100 g 및 892.1±21.2 mg CE/100 g으로 나타났다. 강황 열수 추출물의 라디칼 소거능은 DPPH 및 ABTS 라디칼을 이용하여 측정하였다. 실험 결과 DPPH 및 ABTS 라디칼 소거능을 SC50 값으로 계산하였을 때 각각 188.5±3.0 μg/mL 및 92.0±0.9 μg/mL로 나타났다. 이러한 라디칼 소거능에는 강황 열수 추출물에 함유되어 있는 총 페놀성 화합물 및 플라보노이드가 영향을 미쳤을 것이라고 판단된다. C2C12 myoblast에 강황 열수 추출물을 처리하였을 때 1,000 μg/mL 농도까지 세포 독성이 나타나지 않음을 확인하였으며, 안전성이 확인된 500 μg/mL 농도까지 실험을 진행하였다. 강황 열수 추출물의 H₂O₂에 대한 보호 효과를 측정한 결과 강황 열수 추출물을 처리하였을 때 농도 의존적으로 보호 효과가 나타나는 것을 확인할 수 있었다. 또한, H₂O₂ 처리 후 DCF-DA 방법을 이용하여 세포 내 활성산소종(ROS) 수준을 측정한 결과 강황 열수 추출물을 처리하였을 때 세포 내 ROS 수준이 유의적으로 감소하는 것을 확인하였다. 이상의 결과로부터 강황 열수 추출물은 항산화 활성을 나타냈으며, C2C12 myoblast에 H2O2로 유도된 산화적 스트레스를 감소시키는 효과를 나타내는 것으로 생각된다. The aim of this study was to investigate the antioxidant activities and protective effects of hot water extract from Curcuma longa L. (CLW) on oxidative stress-induced C2C12 myoblasts. Antioxidant activities of CLW were evaluated based on 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activities. Protective effects of CLW on oxidative stress-induced C2C12 myoblasts were determined based on cytotoxicity, H₂O₂ protective activity, and intracellular reactive oxygen species (ROS) level. DPPH and ABTS radical scavenging activities represented by SC50 were 188.5±3.0 μg/mL and 92.0±0.9 μg/mL, respectively. Using C2C12 myoblasts, CLW treatment increased cell viability against oxidative stress-induced cell death. Further, CLW treatment reduced the intracellular ROS level in cells treated with H₂O₂. These results suggest that CLW might have the capability to protect oxidative stress-induced C2C12 myoblasts.
정혜진(Jeong, Hye Jin),박연선(Park, Yun Sun) 한국색채학회 2018 한국색채학회 논문집 Vol.32 No.4
As the era of the 4th Industrial Revolution comes, besides the uniform color of cosmetics, which is a means of expressing individuality and beauty, the trend is changing as the need for customized products optimized for me. The purpose of this study is to analyze the customized lipstick service and color composition of domestic brands which are in service on site in order to analyze the phenomenon for the enhancement of customized service. We visited the store directly and experienced the service. We also studied color by colorimetry through the colorimeter. Personal lipstick service In the process of personal lipstick diagnosis process, personal color system is applied to match the color of the person`s first color is used. To manufacture the product, you can choose from among 240 color types that correspond to your own personal color type, and consist of 120 glossy and 120 matte formulations. Each formulation is based on 8 product colors and 4 blending colors, and the color range is expanded by mixing between these colors. For color configurations, Glossy Lipstick extends the range of color expressions with a combination of the eight basic colors of 2 Reds, Orange, 2 Pinks, Purple, Beige and Brown and 4 blending colors of White, Yellow, Blue and Wine. Matte lipstick consists of 8 basic colors of 3 reds, orange, pink, purple, beige and brown, and 4 blending colors of white, black, yellow and magenta. Customized lipstick services with expanded color groups with a mix of basic 8 colors and 4 blending colors are for on-site manufacturing efficiency. Through this research, I hope that it will help expand the `customized lipstick` service to meet the needs of `personalization` and `customized` that will be continuously expanded in the era of the 4th Industrial Revolution and to establish effective measures.
대장 혈관이형성증에 대한 아르곤 플라즈마 응고 소작술 이후 생긴 자발성 세균성 복막염
정혜진 ( Hye Jin Jung ),류수형 ( Soo Hyung Ryu ),박경식 ( Kyoung Sik Park ),윤원재 ( Won Jae Yoon ),김진남 ( Jin Nam Kim ),김유선 ( You Sun Kim ),문정섭 ( Jeong Seop Moon ) 대한소화기학회 2014 대한소화기학회지 Vol.64 No.2
Spontaneous bacterial peritonitis (SBP) is the most common infection in liver cirrhosis patients, and is not a result of surgery or intra abdominal infection. Argon plasma coagulation (APC) is an endoscopic procedure used with a high frequency electrical current for control of bleeding from gastrointestinal vascular ectasias including angiodysplasia and gastric antral vascular ectasia. This procedure is known to be safe because it uses a noncontact method. Therefore, tissue injury is minimal and up to two to three millimeters. However, we experienced a case of SBP occurring immediately after performance of APC for control of severe bleeding from angiodysplasia in the colon in a patient with liver cirrhosis and hepatocellular carcinoma. (Korean J Gastroenterol 2014,64:115-118)
정혜진 ( Hye Jin Jeong ),김소라 ( So Ra Kim ) 한국패션비즈니스학회 2009 패션 비즈니스 Vol.13 No.4
Recently, young men have become more muscular as they become more interested in physical figure. However, most of these muscular men have fit problems regarding ready-made clothes. In view of this, this study aimed to develop a prototype jacket pattern for muscular men. For this study, five muscular men were selected to put on existing jacket pattern for wearing tests. The regression formula, in which muscular men body measures were adopted, was applied to unsuitable parts, especially the areas determined not to be appropriate in the evaluation of existing jacket pattern wearing tests. After the first and the second jacket pattern wearing tests, the final jacket pattern suitable for muscular men was developed. The results of the study were as follows: In order to make up for the problem of the loosening of the lapel area, due to the development of the chest muscle, the chest circumference line on the chest area of the pattern was cut to be 1.0cm wide; thus, the front length was modified with an increase. The wearing tests found that a wearers felt discomfort from the tight armhole area, so the armhole depth was set to be a little lower than that of ready-made clothes. A muscular men needs much more extra quantity in this area because the upper part of the back side is projected due to the greater development of the trapezius muscle and the deltoid than in average men. Hence, concerning the standard line for the length of the back interscye, ease of 1.0cm was added to the regression equation formula {(0.371×chest circumference+3.145)/2} in order to resolve the discomfort with the back area. Also, for the biacromion length, the upper arm protruded more than the shoulder point of the jacket because of the development of the deltoid and the upper arm muscle, and it was set to be wider than the actual shoulder. In order to solve the problem of discomfort from the narrow neck area during the wearing of a jacket owing to the development of the trapezius muscle, extra ease of 0.5cm was added to chest circumference/12-0.5cm in the existing jacket prototype to the width of back of the neck, and it was corrected to be chest circumference/12.