소아과 의원을 방문한 급성인두염 환자의 인후배양과 emm 유전자형을 이용한 A군 연쇄구균의 역학조사

정현주,이남용,권오영,맹국영,김선주,Jung, Hyun Ju,Lee, Nam Yong,Kwon, Oh-Young,Maeng, Kook Young,Kim, Sunjoo 대한소아감염학회 2003 Pediatric Infection and Vaccine Vol.10 No.2

목 적 : 소아과 의원을 방문한 인두염 환자에서 A군 연쇄구균 분리율을 살펴보고자 하였다. T 항원형과 emm 유전자형을 동정하여 역학적 특성을 살펴보고, 같은 지역의 보균자 결과와 비교하고자 하였다. 방 법 : 2001년 11월부터 2002년 5월까지 경남 진주시에 위치한 한 소아과 의원에서 인두염 환자 246명(남자 123명, 여자 123명)을 대상으로 인후배양을 시행하였다. 슬라이드 응집법으로 T 항원형을 결정하였고, emm 유전자 증폭 후 염기서열 분석을 시행하여 emm 유전자형을 동정하였다. 결 과 : 인두염 환자 246명 중 130명(52.8%)에서 베타용혈성 연쇄구균이 분리되었으며, 그 중 96.1%가 A군이었다. 연령별로는 4세에서 7세가 70.4%로 가장 많았다. T12가 35.2%로 가장 흔하였고, T non-typeable 30.4%, T28 14.4% 순이었다. emm12(28.5%)가 가장 많이 동정되었고, emm75(18.7%), emm22(13.0%), emm2(12.2%) 및 emm8(8.1%) 순이었다. 결 론 : A군 연쇄구균 인두염은 약 50%에서 분리될 정도로 흔하므로, 개인 소아과 의원에서 급성인두염 환자에 대해 항생제 처방 전에 인후배양이 필요할 것으로 사료된다. T항원 및 emm 유전자형은 급성 인두염 환자와 보균자에서 비슷한 분포를 보였다. Purpose : Group A streptococci(GAS) was isolated from the patients with acute pharyngitis. Epidemiological studies using T typing and emm genotyping was performed for GAS and compared with the results of the carriers. Methods : Throat cultures were taken from 246 children(123 boys, 123 girls) from November, 2001 to May, 2002 who visited a pediatrician's office located in Jinju, Gyeongnam province. T types were identified with slide agglutination and emm genotypes were identified with DNA sequencing after amplification of emm genes. Results : One hundred thirty(52.8%) out of 246 children yielded beta-hemolytic streptococci, of which 96.1% were group A. Children from 4 to 7 years old comprised 70.4% of the GAS positive group. T12 were the most common(35.2%) and T non-typeable strains were the next(30.4%). emm12 was most frequent(28.5%), and emm75(18.7%), emm22(13.0%), emm2(12.2%), and emm8(8.1%) were relatively common. Conclusion : Since GAS is so highly prevalent in acute pharyngitis, indeed being half of the population, good clinical practice dictates the systematic employment of throat culture for acute pharyngitis before prescribing antibiotics in a pediatric setting. The distribution of the T antigens and emm genes showed similar pattern between the acute pharyngitis and the carriers.

교류 자기센서 특성 시험장치 설계에 관한 연구

정현주,양창섭,정우진,Chung, Hyun-Ju,Yang, Chang-Seob,Jung, Woo-Jin 한국군사과학기술학회 2015 한국군사과학기술학회지 Vol.18 No.3

This paper describes design and construction results of the measurement system developed on the purpose of measuring properties of AC magnetic field sensors used in the weapon system. The system for measuring the properties of AC magnetic field sensors consist of 3-axis helmholtz coil, signal generator, signal amplifier, sensor data acquisition unit and AC magnetic field sensor property measurement & analysis equipment including the operating software. By using this system, we can measure various properties of AC magnetic field sensor such as sensitivity, linearity and dynamic response in the frequency from 1 Hz to 10 kHz. Finally we also verified its performance by measuring the property of a MAG 639, standard magnetic field sensor of bartington instruments, with the developed measurement system.

사향(麝香) 및 사향(麝香) 배합(配合) 한약제제(韓藥製劑)의 구강(口腔) 투여(投與)가 백서(白鼠)의 기억(記憶) 및 뇌기능(腦機能) 활성(活性)에 미치는 영향

정현주,이유경,채중원,Chung, Hyun-Ju,Lee, Yu-Kyung,Chae, Jung-Won 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.1

Objectives This study was investigated to find how the orally administrated Moschus, herbal combination with Moschus, and herbal combination improves the rats' memory and rats' liver. These medications are generally known asthe memory improvement. Methods This study used the Sprague Dawley rats. They were divided into two groups - SD rats and orally administrated Saline(Control group). 0.473 mg/kg Moschus(HM-A), 153.9 mg/kg herbal composition without Moschus(HM-B), and 165.95 mg/kg herbal composition with Moschus combined(HM-C) Control, saline were orally administered. Each group was trained in the eight-arm radial maze task at the conditions of before oral administrated, and also right after third, sixth, and eighth by oral administration. Lastly, these animals were killed and were tested for brain tissue and serum AST/ALT level to measure how the medications were effected to the liver function. Results The result of radial eight-arm maze task test, the HM-B and HM-C groups showed significant decrease in mistakes from the fourth day of testing. Whereas, the HM-A group showed increasing in the error rate. HM-A and HM-C group of rats had significantly increased amount of acetylcholinesterase in the CA1 region of hippocampus, compared to the control group. Whereas, HM-B and HM-C group had increased level of ChAT compared to the control group. On the other hand, each experimental group did not show any significant difference to the level of serum AST/ALT and the weight ratio of the liver to the body. Conclusions This study provided evidences that the orally administered memory improvement herbal medication, and Moschus were effective to improve memory.

A군 연쇄구균 무증상 감염자에서 페니실린 투여 후 세균제거 효과에 대한 조사

정현주,김선주,Jung, Hyun-Ju,Kim, Seon-Ju 대한소아감염학회 1998 Pediatric Infection and Vaccine Vol.5 No.2

목 적 : A군 연쇄구균 무증상 감염자는 증상은 없지만 A군 연쇄구균이 분리되고 ASO(antistreptolysin O)치가 높은 사람으로서 이들은 류마티스열이나 사구체신염 등 후유증을 일으킬 수 있다. 저자들은 무증상 감염자를 대상으로 경구용 페니실린을 복용하게 하여 이들에서 페니실린 치료 효과를 조사하였다. 방 법 : 상기도 감염 증상이 없는 건강한 초등 학생들을 대상으로 인두배양과 ASO치를 정량적으로 측정하였다. A군 연쇄구균이 분리되고 ASO 치가 400IU/mL 이상인 아동 36명을 대상으로 하여 그 중 22명의 학생은 경구용 페니실린 제제(penicillin V, 500mg. 하루 2회)를 10일간 복용하게 하였고, 14명은 대조군으로 삼고 항생제를 복용하지 않았다. 한달 후 두 그둡 아동에서 동시에 인두배양을 시행하여 A군 연쇄구균 제거율을 비교하고 ASO치를 측정하여 농도 변화를 관찰하였다. 결 과 : 항생제를 복용한 그룹과 복용하지 않은 그음의 A군 연쇄구균 제거율은 각각 91%(20/22)와 50%(7/14)로서 항생제를 사용한 그룹에서 유의하게 높았다(P<0.05). 항생제를 사용한 그룹과 사용하지 않은 그룹에서 ASO치가 100IU/mL 이상 상승한 경우는 각각 22%(4/18)와 30%(3/10)이었고 200IU/mL이상 감소한 경우는 각각 44.4%(8/18)와 40%(4/10)로서 유의한 차이가 없었다. 결 론 : 무증상 감염자를 대상으로 페니실린을 투여했을 때 인두에서 균이 효과적으로 제거되어 페니실린 치료의 타당성을 확인하였다. 그러나 ASO치 감소는 두 그룹간에 유의한 차이가 없었는데, 이는 ASO의 반감기가 걸고 경구용 페니실린의 경우 순응도가 낮기 때문으로 사료된다. 항생제 치료에도 불구하고 ASO치가 상승한 것을 치료 실패로 판정할 때 22%의 치료 실패율을 보였다. Purpose : Asymptomatic infections with positive throat culture for group A beta-hemolytic streptococci(GABHS) and high antistreptolysin O(ASO) concentration may lead to sequelae such as rheumatic fever or acute poststreptococcal glomerulonephritis. Children with asymptomatic infections were treated with oral penicillin V to evaluate the effectiveness of penicillin treatment on the asymptomatic infections. Methods : Throat culture and ASO concentration analysis were performed against healthy elementary school children. Thirty-six children with positive throat culture for GABHS and ASO concentrations of 400 IU/mL or more were divided into two groups. Twenty-two children were treated with oral penicillin V for 10 days, and the others were not treated. Eradication rate of GABHS and the change of ASO concentration between the two groups were compared after one month later. Results : Eradication rates of GABHS between treated and untreated children were 91%(20/22) and 50%(7/14) respectively(P<0.05). Children showing elevation of ASO levels more than 100IU/mL were 22%(4/18) in the treated group and 30%(3/10) in the untreated group, while children showing a decrease of more than 200IU/mL in the ASO level were 44%(8/18) and 40%(4/10) respectively. Conclusion : We confirmed the validity of penicillin treatment, because when we treated the asymptomatic children with penicillin V, the GABHS was eradicated effectively. But there was no significant difference of decrease in the ASO levels between the two groups due to long half-life of ASO or poor compliance. Treatment failure was 22% in terms of elevated ASO levels after penicillin treatment.

자폐아동 가족의 스트레스와 가족적응이 자폐아동의 사회적응에 미치는 경로분석 : 가족탄력성의 조절효과 검증

정현주 ( Hyun Ju Jung ) 한국가족복지학회 2008 한국가족복지학 Vol.13 No.3

능동적 다중 펄스 중첩법(AMPS)을 적용한 펄스형 CO₂레이저의 펄스 성형에 대한 연구

정현주(Hyun-Ju Chung),박성준(Sung-Joon Park),정용호(Yong-Ho Jung),송건주(Gun-Ju Song),김희제(Hee-Je Kim),김휘영(Whi-Young Kim) 대한전기학회 2001 대한전기학회 학술대회 논문집 Vol.2001 No.7

증례보고 : 요관경하 배석술 후 발생한 쇼크

정현주 ( Hyun Ju Jung ),강성학 ( Sung Hak Kang ),임경실 ( Kyung Sil Im ),이재명 ( Jae Myeong Lee ),김대영 ( Dae Young Kim ),홍상현 ( Sang Hyun Hong ),김종분 ( Jong Bun Kim ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.4

One of the most fearful rare complication of ureteroscopic lithotripsy is sepsis. Since sepsis after endourological maneuvers usually occur immediately after procedure, it is important to pay attention to symptoms representing sepsis such as pyrexia, tachycardia, tachypnea, and oliguria. In addition to clinical symptoms, laboratory tests including white blood cell (WBC) count, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and urine and blood cultivating can help to diagnosis of sepsis. We present a case of shock after ureteroscopic lithotripsy, which was suspected with septic shock strongly. (Korean J Anesthesiol 2006; 51: 508~11)

자폐성 장애아동의 사회적응에 영향을 미치는 가족관련 변인 연구

정현주 ( Hyun Ju Jung ),이주희 ( Ju Hee Lee ) 한국가족사회복지학회 2009 한국가족복지학 Vol.25 No.-

본 연구는 가족스트레스, 가족탄력성, 가족적응이 자폐성 장애 아동의 사회적응에 영향을 미치는 영향에 대해서 알아보기 위해서 이루어 졌다. 이를 위하여 가족스트레스가 자폐성 장애아동의 사회적응에 미치는 직접효과와 가족탄력성 및 가족적응을 매개로 한 간접효과를 연구모형으로 구성하였다. 수집된 자료는 SPSS 12.0과 확인적 요인분석과 구조방정식 모형분석을 위하여 Amos 7.0을 사용하였다. 추정방법으로는 완전정보 최대우도법(Full Information Maximum Likelihood)을 사용하였다. 분석 결과 가족스트레스가 자폐성 장애아동의 사회적응, 가족탄력성, 가족적응에 이르는 경로계수가 통계적으로 유의미 하였다. 그리고 가족탄력성이 가족적응에 이르는 경로계수가 통계적으로 유의미하였다. 또한, 가족적응이 자폐성 장애 아동의 사회적응에 이르는 경로계수가 통계적으로 유의미하였다. 그러나 가족탄력성이 자폐성 장애 아동의 사회적응에 이르는 경로계수는 통계적으로 유의미하지 않았다. 마지막으로 연구의 의의, 제한점 및 후속연구를 위한 제언을 제시하였다. This study aims to research the influence that social family stress, family resilience, and family adaptation have on social adaptation of autistic children. Thus, this study attempts to examine the direct effect of family stress and mediation effect of family resilience, and family adaptation on the social adaptation of autistic children. Statistical analysis was performed according to SPSS 12.0 and AMOS 7.0 for factor analysis and Structural Equation Modeling(SEM). According to results, it was found that family stress has meaningful statistical difference in the degree of social adaptation of autistic children, family resilience, and family adaptation. Also family resilience has meaningful statistical difference in the degree of family adaptation. And family adaptation has meaningful statistical difference in the degree of social adaptation of autistic children. But family resilience has not meaningful statistical difference in the degree of social adaptation of autistic children. Finally, the significance of this study, its limitation and further research was discussed.

반자초 단청 문양과 배색

정현주(Hyun-ju Jung) 한국색채학회 2013 한국색채학회 논문집 Vol.27 No.3

세계화가 가속화 될수록 우리 문화의 역사성과 고유성을 바탕으로 한 지역문화가 세계 시장에서 차별화 할 수 있는 강력한 경쟁 수단으로 대두되고 있다. 지역 문화 중에서 색채는 세계 속의 한국이 개성있는 지역 문화를 가질 수 있는 요인이 되면서 동시에 지역 문화의 특성을 나타내는 중요한 도구이므로 이에 대한 심도 있는 연구가 필요하다. 조사방법으로 총 10권으로 구성된 「북한의 전통사찰」에 단청 화보를 대상으로 하였으며 조사된 지역으로 강원지역, 평안지역, 함경지역 그리고 황해도 지역으로 분류하여 연구했다. 조사 대상은 사찰 천정 반자초 중에서 연화를 중심으로 문양과 배색을 조사하여 x<SUP>2</SUP> 검증을 실시하였다. 연구 결과로 반자초 문양 형태와 꽃잎 수는 지역적으로 유의한 차이를 나타났으며. 반자초 배색에서 반자 바탕색은 주로 먹과 다자였지만 지역에 따라 차이를 나타냈고 연화 속꽃, 겉꽃, 배주기 배색 그리고 연화 주변문양 배색들도 지역에 따라서 차이를 나타내고 있었다. 그러나 반자초 바탕색으로 다자가 많이 나타난 점과 주변 색들에서 난색계열이 많이 나타난 점은 추운 북한 사찰 내에 따스함을 느끼기 위한 배색임을 알 수 있다. In the era of globalization, Korean regional culture based on inherent characters became a powerful competition way that could differentiate Korean culture in world market. The regional color is a important base of Korean culture in the world to keep on studies it. This study investigated Dancheong of the Buddhist temples in North Korea to understand the Korean color deeply. Systematic investigation into Dancheong of the Buddhist temples was not enough despite many studies of the temples at some of the regions in South Korea. So, this study investigated Yeonhwa of Banjacho of the interior of the temples in North Korea. The Dancheong pictorials of "Traditional Buddhist Temples in North Korea" with 10 volumes are based to understand Banjacho patterns and coloring of the ceiling in North Korea. Results of Dancheong patterns including shapes of lotus and number of leaves were significant by regions in North Korea. Dancheong coloring, in addition, Dancheong inner flower coloring, outer flower coloring and adjacent pattern coloring varied depending upon regions in North Korea.

루브릭을 활용한 자유탐구 지도가 초등학생의 자유탐구에 미치는 영향 및 인식 조사

정현주 ( Hyun Ju Jung ),임성만 ( Sung Man Lim ),천재순 ( Jae Sun Chun ) 한국초등과학교육학회 2013 초등과학교육 Vol.32 No.3

The purpose of this research is to find the effect of the lesson using open-inquiry report Lubric on openinquiry standard and science process skill; to find the change of cognition on open-inquiry for elementary school 5th grade students. Two classes (elementary school 5th grade) were selected which located in a small and medium-sized city for this research and they were separated as an experimental group and a comparative group. Open-inquiry lesson was done by referring teaching method which introduced through the curriculum. The procedure was understanding about open-inquiry, making open-inquiry subject, planning, and performing inquiry, mid-term, performing inquiry, making a report, presentation, and evaluation. Open-inquiry report Lubric which developed by Sook-Kyung Kim et al. (2010) was provided to the experimental group. Comparative group was instructed by using open-inquiry report which introduced to the elementary school 5th grade science text book. Interview paper was developed in order to check out the effect of the research by using a test paper of science process skill. The following could be found out through the research. After open-inquiry lesson, 10 open-inquiry reports(5 reports from experimental group, 5 reports from comparative group) have been drawn at random as samples from the total 62 sets (30 reports from experimental group, 32 reports from comparative group) and evaluated by a researcher and two elementary school teachers who have master degree. The reliability of the 3 scorers was 0.923 of mean correlation coefficient. And then the researcher evaluated all open-inquiry reports. The average score of open-inquiry report was 66.78 for experimental group, 54.27 for comparative group, respectively. And there was a significant difference at p<0.05 level as a result of the t-test. The experimental group rated high at p<0.05 level according to the analysis of post-science process skill test. According to the result of survey, both experimental group and comparative group had understood open-inquiry activity. It was especially rated high for experimental group on understanding scientific inquiry process, interest and satisfaction in open-inquiry and re-participation rate. By interviewing experimental group, it is recognized that the students utilized Lubric very well through the overall process. Finally, self-evaluation was done during open-inquiry activity and it was reported that the students gained more knowledge about science and changed to positive about science. As a result, the lesson using open-inquiry report Lubric was effective for students to improve writing skill of an open-inquiry report and science process skill and finally changed the cognition to positive about open-inquiry lesson.