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Rat에서 Elevated plus-maze를 이용한 황금의 항불안 효과
정지욱,안남윤,박성환,오진경,오혜림,이보경,엄애선,김범수,김동현,류종훈 한국생약학회 2004 생약학회지 Vol.35 No.1
Scutellaria baicalensis Georgi is one of most important medicinal herbs in traditional chinese medicine. The object of this study was to determine the effects of the water extracts of Scutellaria baicalensis (SB) on the anxiolytic-like activities in the elevated plus-maze (EPM) test. The water extracts of SB (100, 200, or 400 mg/kg) were orally administered to male SD rats for 3 days, and behavioral tests for the anxiolytic activity were performed. SB (100, 200, or 400 mg/kg) significantly increased in time-spent and arm entries into the open arms of the EPM compared with the control group. Futhermore, those anxiolytic-like activities of SB were antagonized by flumazenil (a GABAA antagonist, 3 mg/kg), but not by pindolol (a 5-HT1A antagonist, 10 mg/kg). SB did not cause myorelaxant effects in the horizontal wire test at any dosage regimen. Therefore, these findings suggest that SB promote the anxiolytic-like activity mediated by GABAergic nervous system in rats.
정지욱,이민수,조태식,Jeung, Ji-Wook,Yi, Min-Soo,Cho, Tae-Sik 한국전기전자재료학회 2010 전기전자재료학회논문지 Vol.23 No.2
The crystallization of FePt/MgO(001) magnetic thin films of various thicknesses has been studied using synchrotron x-ray scattering, atomic force microscope, and vibrating sample magnetometer. In film with a 499-$\AA$-thick, face-centered tetragonal, ordered FePt phase was dominantly crystallized into perpendicular (001) grains keeping the magnetically easy c-axis normal to the film plane during annealing. In film with a 816-$\AA$-thick, however, longitudinal (110) grains keeping the c-axis parallel to the film plane were grown on top of the perpendicular (001) grains. The behavior of the magnetic properties was consistent with the thickness dependence of the crystallization. We attribute the thickness dependence of the crystallization to the substrate effect, which prefers the growth of the c-axis oriented perpendicular grains near the film/substrate interfacial area.
정지욱,서진형 한국부동산경영학회 2010 부동산경영 Vol.1 No.-
The trade of real estate in Korea is concluded on the basis of the private contract between the parties of sales/purchase of real estate without thorough verification, thereby resulting many disputes after establishment of contract, which impedes the liquidity of real estate market. Since the scale of accident in the trade of real estate becomes tremendous due to increased investment to real estate and preference in real estate and the fraudulent method is developing delicately these days, the property loss and mental damage are expanding to social issue beyond the individual dimension. However, the state is unable to set the fundamental countermeasure to prevent this problem. Thus, this dissertation checked problem of accident in the trade of real estate through relevant law and literature as well as interview with relevant staffs and presented the improvement method. It was divided into short-term task and mid-term and long-term task in the viewpoint of system. Analyzing the trend of judicial case of court these days, the responsibility for mistake due to the victim's negligence of obligation in the trade of real estate is recognized to considerable extent. Thus, it is required to recognize that the person himself is responsible for trade of real estate. Since risk in the trade of real estate cannot be completely eliminated only with the effort of the party of trade to avoid the risk, it is essential to promptly legalize the deficient system and to prepare solution by making coincident opinion through social discussion on the systematic improvement
유바리국제판타스틱영화제의 벤치마킹한 장르영화제로서의 가능성 : 평창동계올림픽 이후 유휴시설의 활용방안
정지욱,김형래 글로벌문화콘텐츠학회 2018 글로벌문화콘텐츠학회 학술대회 Vol.2018 No.1
메가 이벤트인 평창동계올림픽 후 활용 가능한 유휴시설에 스포츠영화, 자연 및 산림영화 등의 장르영화제를 개최함으로써 유휴공간의 활용과 지역 이미지 개선, 관광객 유입을 도모할 수 있을지를 모색해 본다.
정지욱 한국생약학회 2021 생약학회지 Vol.52 No.1
Belamcandae Rhizoma (BR), the rhizome of Belamcanda chinensis (L.) DC., possesses various biological properties such as anti-inflammatory activity, antioxidant activity and antimutagenic activity. However, there have been no studies on the anti-amnesic effect of BR. In this study, we assessed the improvement effect of BR extract on scopolamine-induced amnesia in mice. ICR mice were administrated with BR (50, 100 or 200 mg/kg, p.o.) and were subsequently injected of scopolamine (1 mg/kg, i.p.) 30 min before behavioral tasks (Y-maze, passive avoidance and Morris water maze tasks). To further assess the possible mechanisms of BR, the ex vivo acetylcholinesterase (AChE) activity was also evaluated. BR could ameliorate scopolamine-induced memory impairment and could regulate the cholinergic function by inhibiting the AChE activity. These data demonstrated that BR exert candidate extract against amnesia by restoring the cholinergic activity.
영화제와 청소년 영화교육 : 일본과 독일, 그리고 국내영화제를 중심으로
정지욱,김형래 글로벌문화콘텐츠학회 2019 글로벌문화콘텐츠학회 학술대회 Vol.2019 No.2
영화가 청소년들에게 미치는 영향은 지대하다. 학교에서 특별교육을 통해 이뤄지는 영화교육(미디어교육) 이외에 국제영화제 부대행사로 개최되는 다양한 청소년 영화교육은 공교육 체제 안에서 일방적으로 전달하는 형식과 틀을 벗어나 자유롭고 다양한 형식의 실험을 진행 중이다. 이 영화제들 역시 현역에서 활동하는 영화제작자, 영화감독들이 직접 참여해 다양한 워크숍과 토론회를 열어 청소년 영화 교육에 기여하고 있다. 이들 영화 교육은 청소년들의 다양한 문화콘텐츠 형성에 기여할 것이다. 일본과 독일, 그리고 한국에서 어린이·청소년영화제의 부대행사로 개최되는 교육프로그램을 살펴보다 적극적이고 체계적인 영화교육의 방도를 찾아보고자 한다. 특히 가톨릭문화원 어린이 영화제 <날개>와 부산국제어린이청소년영화제의 사례는 해외 사례와 함께 뒤늦게 시작했지만 좋은 성과를 거두고 있는 안동 국제 청소년 영화 캠프와 김포청소년영화제의 지속적인 개최의 촉진제가 될 것이다. 이들 영화제와 영화교육에 대한 연구는 보다 안정적인 청소년 영화교육을 위해 필요한 것이라 하겠다.