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정기환,김수환,임지형,강윤진 대한두개저학회 2016 대한두개저학회지 Vol.11 No.1
Chordoma is a rare tumor derived from the remnants of the notochord. Chordomas are second most commonly discorvered within the Skull base/Clivus. Clivus chordoma presents as nasopharyngeal mass can be mistaken for primary benign nasopharyngeal mass. To minimize delay in diagnosis, nasopharyngeal extension of Clivus chordoma should be considered in the differential diagnosis of any mass forming lesion in nasopharynx.
가토 모델에서 인체지방유래 줄기세포가 슬관절의 퇴행성 변화에 미치는 영향
정기환,김석권,정재우,허정,권용석,이근철 대한성형외과학회 2008 Archives of Plastic Surgery Vol.35 No.6
Purpose: The survival of bone marrow derived stem cell was reported several times. But the survival of adipose tissue derived stem cells(hASCs) was not mentioned on. We studied the adipose tissue derived stem cell's survival and effect on articular cartilage in rabbits. Methods: Osteoarthritis was induced in twenty New Zealand white rabbits by intraarticular injection of monosodium iodoacetate(MIA). After four weeks, hASCs were also injected into the knee joints space without any vehicle, but the control group received phosphate buffered saline only. The histologic grade of articular cartilage was measured in 4 and 8 weeks after the transplantation of hASC and the viability of injected stem cells measured by Fluorescent in situ Hybridization (FISH) examination. Received January 24, 2008 Revised June 16, 2008 Accepted September 3, 2008 Address Correspondence: Seok Kwun Kim, M.D., Ph.D., Department of Plastic & Reconstructive Surgery, College of Medicine. Dong-A University, 1,3 ga, Dongdaeshin-dong, Seo-gu, Busan 602-715, Korea. Tel: 051)240-2807/Fax: 051) 243-5416/E-mail: sgkim1@dau.ac.kr *본 논문은 2007년 제63차 대한성형외과학회 추계학술대회에서 구연 발표되었음. Results: After 4 and 8 weeks from hASCs transplantation, histologic grade was not significantly difference between two groups(p>0.05), and the Y chromosome of the transplanted hASCs was not detected in articular cartilage. Conclusion: We found that direct injection of hASC in joint space didn't work on damaged articular cartilage repair.