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Toremifene 사용과 관련된 자궁내막 폴립 1 예
정집광(Jib Kwang Chung),이석민(Seok Min Lee),박은희(Eun Hee Park),방성윤(Sung Yun Bahng),김태성(Tae Sung Kim),문성택(Seong Taek Mun),진소영(So Young Jin) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.7
Antiestrogens have been widely used in the treatment of breast cancer patients. Although tamoxifen is one of the most prevalent antiestrogens, some reported its hepatocarcinogenic effects and the long-term treatment may increase the risk of endometrial and gastrointestinal cancer. Toremifene is an interesting new antiestrogen and have a similar antitumor efficacy as tamoxifen, with less side-effect including less uterotrophic effect compared to tamoxifen, in mice. we report a case of endometrial polyp which were associated with toremifene use, in postmenopausal woman with breast cancer, with a brief review of literature.
자궁경부 종양에서 EGFR, TGF-alpha 및 Ki-67 발현에 대한 면역조직학적 연구
정집광(Jib Kwang Chung),이슬기(Seul Kee Lee),김민관(Min Kwan Kim),배동한(Dong Han Bae),김창진(Chang Jin Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.4
N/A Objective : Cervical carcinoma of the uterus, the most common maliganacy among women in Korea, which its etiology and pathogenesis are not yet determined. Recently, since it has been found about the function of the growth factor and its receptor, involved in the regulation of cellular growth and differentiation, many studies have been undertaken about the role of growth factors and its receptors in the growth and differentiation of the tumor cell. Methods : In this study, we examined the expression of EGFR, TGF-alpha and Ki-67 in 50 CINs and 20 invasive cervical cancers using immunohistochemical stain. Results : Positive rate of EGFR was 92% in CIN, 80% in invasive cancer, negative rate of TGF-alpha was 74% in CIN, 80% in invasive cancer and Ki-67 labelling index(LI) in normal basal cell, CIN I-II, CIN III were 5±0.7, 13±2.5, 65±5.4 repectively and in invasive cancer, LI was over 90. from this result as cervical carcinoma progresses, the expression of EGFR and Ki-67 increase while that of TGF-alpha decreases. Conclusion : As cervical carcinoma progress, the expression of EGFR and Ki-67 increase while that of TGF-alpha decreases. Further studies on the expression of EGFR and TGF-alpha and its growth-stimulation mechanism in cervical carcinoma are warranted to establish the pathogenesis of the cervical carcinoma.
이동 컴퓨팅 환경에서 선택적 메시지 로깅을 이용한 복귀없는 검사점 기법
정광식(Kwang-Sik Chung),유헌창(Heon-Chang Yu),황종선(Jong-Sun Hwang) 한국정보과학회 1998 정보과학회논문지 : 시스템 및 이론 Vol.25 No.7
이 논문은 이동 환경에서 이동 호스트의 복귀를 없애기 위해 송신자 기반의 선택적 메시지 로깅을 이용한 검사점 기법을 제안한다. 검사점은 이동 호스트의 메시지 송수신 상태에 따라 결정되며, 메시지에 대한 로그 부담을 줄이기 위해 잠재적 고아 메시지에 대해서만 선택적으로 로깅을 한다. 잠재적 고아 메시지에 대한 로깅은 이동 호스트가 복귀하는 것을 막아 주며, 각 이동 호스트가 시간상 가장 마지막 검사점 하나만을 저장하고도 결함 발생시 전역 검사점의 일관성을 유지할 수 있도록 한다. 잠재적 고아 메시지에 대한 정보는 기지국이 관리한다. 회복을 위해 이동 호스트간의 관계는 메시지 의존 트리에 저장되며, 메시지 의존 트리는 기지국이 관리한다. 잠재적 고아 메시지에 대한 로그와 메시지 의존 트리는 실패 발생시 항상 일관된 전역 상태를 유지할 수 있게 해 준다. This paper presents a checkpointing protocol for mobile computing environments-asynchronous checkpointing protocol combined with a selective sender-based message logging for avoiding the rollbacks. The message sending/receiving state of mobile host determines the time to lake the checkpointings. And only we potential orphan message is selectively logged for reducing the overhead of message logging. The logs of potential orphan messages prevent the mobile hosts from rolling back and always make the latest global checkpoints consistent although at a failure. MSS maintains the logs of potential orphan messages. For the recovery the dependency relationships of mobile hosts are saved as Message Dependency Tree and the Message Dependency Tree is maintained at the MSS. At a failure the logs of potential orphan messages and MDTs are used for making the consistent global state.