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정경숙,임현술,Jeong, Kyoung Sook,Lim, Hyun-Sul 대한임상독성학회 2009 대한임상독성학회지 Vol.7 No.1
A 52-year-old man was found dead in the driver's seat of his tank lorry. The tank lorry was used to transport industrial wastewater to a disposal plant; the material was transferred into a storage tank with the help of compressed air. The wastewater contained methylene chloride and 2-chloropyridine. No respiratory protective equipment was used while working under these conditions. The autopsy report showed extensive edema and congestion of the brain, lung, and intraperitoneal organs. The concentrations of methylene chloride in lung and brain were reported at 398 and 67 mg/kg, respectively.
정경숙 ( Kyoung Sook Jeong ),임현술 ( Hyun Sul Lim ) 대한임상독성학회 2008 대한임상독성학회지 Vol.6 No.2
A 52-year-old man was found dead at a driver’s seat of his tank lorry. He transported industrial waste water to a waste water disposal plant by his tank lorry and transferred it into a storage tank with the help of compressed air. The waste water contained methylene chloride and 2-chloropyridine, and he worked this process without using respiratory protective equipment. Autopsy showed extensive edema and congestion of brain, lung, and intraperitoneal organ. The concentrations of methylene chloride in lung and brain were 398 and 67 mg/kg, respectively.
김양호,이지호,심창선,정경숙,Kim Yang Ho,Lee Ji Ho,Sim Chang Sun,Jeong Kyoung Sook 대한임상독성학회 2004 대한임상독성학회지 Vol.2 No.2
Arsenic poisoning has three types of poisoning. First, acute arsenic poisoning is usually caused by oral intake of large amount of arsenic compound with purpose of homicide or suicide. Second, chronic arsenic poisoning is caused by inhalation of arsenic in the occupational setting or by long-term oral intake of arsenic-contaminated well water. Third, arsine poisoning occurs acutely when impurities of arsenic in non-ferrous metal react with acid. Clinical manifestation of acute arsenic poisoning is mainly gastrointestinal symptoms and cardiovascular collapse. Those of chronic poisoning are skin disorder and cancer. Arsine poisoning shows massive intravascular hemolysis and hemoglobinuria with acute renal failure. Exposure evaluation is done by analysis of arsenic in urine, blood, hair and nail. Species analysis of arsenic is very important to evaluate inorganic arsenic acid and mono methyl arsenic acid (MMA) separated from dimethyl arsenic acid (DMA) and trimethyl arsenic acid (TMA) which originate from sea weed and sea food. Treatment with dimercaprol (BAL) is effective in acute arsenic poisoning only.
미토콘드리아 DNA의 제한요소 분석법(RFLP)에 의한 느타리 버섯의 분류
황소영,정경숙,이미경,조남영 대전대학교 기초과학연구소 1996 自然科學 Vol.7 No.2
황악산에서 채집된 느타리 버섯의 분류를 위하여, 4종류의 느타리과에 속하는 버섯들과 함께 미토콘트리아 DNA를 분리하여 여러 제한효소로 처리 후 나타나는 절편들의 양상을 비교하여 계통분석을 수행하였다. 여러 제한효소 중 4가지의 제한효소를 선택하여, 절편을 얻은 후 NTSYS-pc program을 사용하여 분석한 결과, 채집된 버섯은 형태학적으로 느타리와 유사하였지만, RFLP 법으로 판단할 때 오히려 사철느타리와 더 연관성이 있는 것으로 나타났다. 따라서 보다 객관적인 분류를 위하여 형태학적 분류만으로는 한계가 있고, 분자생물학적인 분석 등 다양한 기준에 의해서 수행되어야 한다고 판단된다. To identify the strain (TUM004) which was isolated from Mt. hwangak, the restriction enzyme analysis of mitochondrial DNA was accomplished using four different strains of Pleurotus as a standard strain. Pattern of fragments generated by 4 different restriction enzymes (BamHl, EcoRl, Hindlll, Xdal)was analyzed by using NTSYS-pc program. Results showed that TUM004 was more related to Pleurotus florida rather ,than to Pleurotus ostreatus. Results also imlpy that RFLP of mitochondrial DNA is a good classification system to identify the unknown strain to the genus level.