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      • KCI등재

        분심기음(分心氣飮)이 고혈압 백서와 인간유래 혈관내피세포주(ECV 304)에 미치는 영향에 대한 연구

        전연이,박창국,이소연,윤현덕,신오철,박치상,Jeon, Yeon-Yi,Park, Chang-Gook,Lee, So-Yeon,Yoon, Hyeon-Deok,Shin, Wo-Cheol,Park, Chi-Sang 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.1

        Object : This study was designed to research whether the protection and inhibitory effects of cardiovascular diseases in L-NAME induced rat or ECV 304 cell lines through the Cell morphological pattern, Tunel assay, LDH activity, heart rate, blood pressure and immunohistochemistric analysis by Boonsimgieum water extract Methods : Nitric oxide(NO) play an important role in normal and pathophysiological cells including as a messenger molecule, neurotransmitter, microbiocidal agent, or dilator of blood vessels and artheriosclerosis, hypertension, myocardial infarction, respectively. Endothelial cell products can modulate the magnitude of a response to a vasoconstrictor, as evinced by the greater constriction after endothelium removal or NO synthesis blockade. To investigate that Boonsimgieum in the potential contribution of the levels of nitric oxide generated by endothelial nitric oxide synthase (eNOS) and the mechanisms of protection against NG-nitro-L-arginine methyl ester (L-NAME), human ECV 304 cells, which normally do not express eNOS, were expressed by L-NAME. L-NAME stimulated rat or cells were found to be resistant to injury and delayed death following the Boonsimgieum. Inhibition of nitric oxide synthesis abolished the protective effect against L-NAME, thrombin and collagen exposure. Interestingly, such effects have been observed during stimulation with agents such as phenylephrine and KCl on L-NAME mediate rats, were damaged by the NOS inhibitor L-NAME. Result : As the result of this study, In group, the anti-apoptosis and necrosis in the cardiovascular system have a potential capacity for prevented, protected and treating the diseases of cardiovascular system, against the necrosis of rat and ECV 304 cells with Caspase 3 and calpain expression by L-NAME is promoted. Conclusion : these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.

      • KCI등재후보
      • KCI등재

        아로마테라피를 이용한 비만관리효과의 메타분석

        전연,우나리야 한국피부과학연구원 2014 대한피부미용학회지 Vol.12 No.2

        This study combined research on the effectiveness of obesity management using aromatherapy with a metaanalysisof the effects of body composition and blood lipids. 31 Korean dissertations and journal articleswere analyzed and sample count and standard deviation values used in these materials to measure theeffectiveness of obesity management programs using aromatherapy were entered into Excel to calculate thebasis for research results. Examining the general characteristics of research on obesity management usingaromatherapy, it was found that the sample size of many studies was below 6-10 people, the treatmentmethods mainly involved massage therapy, and oils used were mainly juniper, cypress, and grapefruitcarrier oils with jojoba and almond. The weighted effect size of obesity management with body compositionfactor was a median of 0.33 and sub-factor effect sizes were body fat percentage (0.39), WHR (0.32), bodyweight (0.28), and BMI (0.23) respectively. The weighted effect size of blood lipids was a median of 0.30 andsub-factors were found to have significant effects, with TC (0.43) and LDL-C (0.36). Looking at the abovemeta-analysis research results overall, aromatherapy can be verified as an effective obesity managementmethod as it influences TC and LDL-C and reduces body fat percentage.

      • KCI등재

        중국 인터넷 쇼핑몰 특성에 대한 지각이 고객 만족과 재구매의도에 미치는 영향에 관한 연구 : 인지부조화의 조절효과

        전연,이선수 한국상업교육학회 2017 상업교육연구 Vol.31 No.3

        인터넷 쇼핑 환경은 정보통신기술의 발전과 함께 지속적으로 개선되고 있다. 성숙기에 접어든 중국의 인터넷 쇼핑시장은 이러한 신기술을 이용한 쇼핑환경 개선에 적극적으로 나서고 있으나 고객에 대한 서비스 관리는 아직 미흡한 상태이다. 인터넷 쇼핑시장이 지속적으로 성장하기 위해서는 인터넷 쇼핑몰에 대한 소비자의 호의적인 지각이 중요하다. 따라서 본 연구에서는 인터넷 쇼핑몰의 상품특성과 배송서비스에 대한 소비자의 지각이 중요하다고 여기고, 이러한 요인들에 대한 소비자의 지각이 이용고객의 만족도와 재구매의도에 미치는 영향을 규명하고자 한다. 또한, 인터넷 쇼핑몰 이용자가 선택적 대안을 결정하는 과정에서 나타날 수 있는 인지부조화의 고객만족도에 대한 조절효과에 대하여 살펴보고자 하였다. 이를 위해 본 연구에서는 인터넷 쇼핑몰에서 제품을 구매한 경험이 있는 중국인 고객 243명을 표본으로 하여 실증분석을 하였다. 실증분석 결과 상품특성(상품가격, 상품구색)과 배송서비스(친절성, 반품성)가 고객 만족에 긍정적인 영향을 미치고, 고객 만족이 재구매의도에 유의한 영향을 미치는 것으로 나타났다. 인지부조화의 고객만족에 대한 조절효과를 검증한 결과 상품구색의 경우에 유의적인 영향이 있는 것으로 확인되었다. 본 연구의 결과는 중국시장에서 인터넷 쇼핑몰을 운영하려는 기업들이 중요하게 고려해야 할 요인들에 대한 실무적인 시사점을 제공한다. Online shopping environment is continuously improving with the development of information and communication technology. The online shopping market in China, which has reached the maturity stage, is taking an active role in improving the shopping environment using these new technologies. However, service management for customer is still insufficient. In order for the online shopping market to continue to grow, it is important to favorable perception of consumers shopping on the Internet. Therefore, in this study, it is considered that consumer's perception of product characteristics and delivery service of online shopping mall is important. The purpose of this study is to investigate the effect of consumer's perception on these factors on customer's satisfaction and repurchase intention. In addition, we examine the moderating effects of cognitive dissonance on customer satisfaction, which can be seen in online shopping mall users' selection of alternatives. For this purpose, this study conducted an empirical analysis using 243 Chinese customers who have purchased products at online shopping malls. This study confirmed the reliability and validity of constructs through exploratory factor analysis and internal consistency analysis, and tested hypotheses through hierarchical regression anlaysis. The results of the analysis showed that the product characteristics(i.e., product price and assortment) and delivery service(i.e., kindness and returnability) had a positive effect on customer satisfaction, and customer satisfaction had a significant influence on repurchase intention. For the analysis of the moderating effect of cognitive dissonance on customer satisfaction, there was a significant influence only in the case of product assortment. The results of this study provide practical implications for the factors that should be considered by the company that operates the Internet shopping mall in the Chinese market.

      • KCI등재

        석창포(石菖蒲)가 뇌허혈(腦虛血)을 유발(誘發)시킨 백서(白鼠)에서의 뇌신경보호효과(腦神經保護效果)

        금현수,전연이,이은주,박치상,박창국,허진화,양재하,조정숙,강승준,Keum, Hyeon-Su,Jeon, Yeon-Yi,Lee, Eun-Ju,Park, Chi-Sang,Park, Chang-Gook,Heo, Jin-Hwa,Yang, Chae-Ha,Cho, Jung-Sook,Kang, Seoung-Jun 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.3

        Object: Acori graminei rhizoma(AGR) extract is clinically used to treat the cerebral ischemia in Korea. The present study was undertaken to study the neuroprotective effect of AGR extract in middle cerebral artery occlusion(MCAO) rats. Methods: Changes of extracellular levels of glutamate, aspartate, GABA, glycine, taurine, tyrosine, alanine in striatum were collected at 20 minutes interval by in vivo microdialysis and then analyzed by HPLC(high performance liquid chromatography) in rats subjected to permanent focal cerebral ischemia induced by 2 hours of MCAO. AGR extract was orally administrated before MCAO. Different animals were used for measurement of cerebral infarction volume induced by 24 hours of MCAO with TTC staining and image analysis. Result : The infarction volume was decreased and focal cerebral ischemia - induced increase of extracellular glutamate, aspartate, and tyrosine were inhibited after the treatment of AGR extract. On the other hand, the increase of glycine and alanine not but GABA and taurine were enhenced after the treatment of AGR extract. Conclusion: These results suggest that AGR extract can playa role in protecting against cerebral ischemia by regulating extracellular levels of excitatory and inhibitory amino acid neurotransmitters.

      • KCI등재

        가미음천이진탕(加味陰喘二陳湯) 투여환자(投與患者) 33례(例) 분석보고(分析報告)

        최해윤,최영아,전연이,김종대,Choi Hae-Yun,Choi Young-Ah,Jeon Yeon-Yi,Kim Jong-Dae 대한한의학방제학회 2000 大韓韓醫學方劑學會誌 Vol.8 No.1

        Objectives: We intented to find out the effect of Gami-Eumcheonyijintang to patients who complain with coughing and to make it useful for treating the patients with the symptom. Materials and Methods: We examined the medical of 33 patients who visited with the symptoms of coughing, sputum in Kyungsan University, Hospital of Oriental Medicine from April, 1996 to February, 1999. and we collected the result of the administration with Gami-Eumcheonyijintong. We aimed to find any change in the symptoms, reappearance after recovery, and any special facts with the medicine surveying by telephoning to the patients. Results : the results are as follows, 1. It showed that patients who were under thirties showed higher rate of recovery(75.00%) than who were over thirties(52.94% ). 2, The acute-stage patients who were recovered in less than four weeks showed higher rate of recovery than those chronic-stage patients who were recovered in more than eight weeks. 3. The patients who didn't have the symptoms of sputum or had less serious problems of it with severe coughing showed relatively the highest rate of recovery(73.91% ). 4. The patients who showed the coughing symptom right after URI without any past constitutional history showed the highest rate of recovery(73.68% ). Conclusion : From the above result, we found that Gami-Eumcheonyijintang is more effective in early coughing symptom after URI than chronic stage coughing symptom. It is thought that more studies about medicine composition are needed in the further.

      • KCI등재후보

        대승기탕(大承氣湯) 투여 후 편폐(便閉 ), 번조(煩燥), 불면(不眠)호전된 중풍 환자 치험 1례

        김봉석,임희용,최빈혜,김대준,전연이,조종관,변준석,오중한,Kim, Bong-Suk,Lim, Hee-Yong,Kim, Dong-Woo,Choi, Bin-Hye,Kim, Dae-Joon,Jun, Yeon-I,Cho, Chong-Kwan,Byun, Joon-Seok,Oh, Jung-Han 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2

        In the early stage of stroke, the symptoms of constipation, chest discomfort and insomnia may appear in addition to the general symptoms such as specific limb weakness, dysphasia, headache, dizziness etc.. We administered Daeseungkitang(大承氣湯) to the patient diagnosed with cerebral infarction by MRI. He clearly displayed the usual syndromes of stroke(實證), endogenous wind stirring in the liver(肝風內動) and acceleration of upper chest functions(上焦火盛), ascertainned by Oriental Medical methods. After treatment with Daeseungkitang(大承氣湯), the constipation, chest discomfort and insomnia improved along with improvement of general symptoms of stroke.

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