1963年 慶北地區에 侵入한 El Tor Cholera의 疫學的 觀察

全燾基,鄭在奎,文榮石,李在九,金炅守,丁洛珍,金斗熙 대한의학협회 1964 대한의학협회지 Vol.7 No.8

1973年 大邱地方患者에서 分離한 Salmonella 및 Shigella의 菌型

全燾基,金沅秀,薛成用,朴興烈,李孝順 中央醫學社 1974 中央醫學 Vol.26 No.4

One hundred and thirty-three strains of Salmonella and 18 of Shigella were isolated from patients visited Kyungpook University Hospital and Taegu Presbyterian Hospital during the period from January through' December '1973, and their characteristics were studied. All strains of Salmonella were typed as Salmonella typhi. Among 18 strains of Shigella, 5 strains were classified as Shigella flexneri la, four as Sh. flexneri 2a, and 9 as Sh. sonnei. A sharp increase in the proportion of Shk sonnei among strains of Shigella was noted.

응집반응(凝集反應)을 이용(利用)한 0항원변이균(抗原變異菌)의 선택(選擇)에 관(關)하여

전도기,안태휴 대한피부과학회 1956 대한피부과학회 학술발표대회집 Vol.8 No.-

Flexer 군적리균(群赤痢菌)의 Tannic acid hewmagglutiuation에 대(對)하여(초록(抄錄))

전도기,양용태,Jeon, Do-Gi,Yang, Yong-Tae 대한미생물학회 1958 大韓微生物學會誌 Vol.1 No.1

葡萄狀球菌感染症의 疫學 : Bacteriophage typing을 中心으로

全燾基 醫藥係社 1962 綜合 醫學 Vol.7 No.11

大邱地方에서 分離한 Salmonella 及 Shigella에 對하여

全燾基,金正壽,安斗洪,李在九 中央醫學社 1963 中央醫學 Vol.5 No.3

Salmonella and shigella isolated from patients in Taegu area during the period between September of 1961 and January of 1963 were studied. Among 219 strains of salmonella, 208 were S. typhi and the rest was S. Paratyphi A. No other serotypes was observed. Among 43 strains of shigella, 38 strains were classified as B group. Strains belonging to A, C or D groups were found to be only one or two in number. Out of 38 strains belonging to B group, 18 strains were classified as Sh. flexneri 2a. The next predominant serotypes within B group was Sh. flexneri 3a. and followed in decreasing order by la, 4a and 2b. Most of the salmonella were sensitive to dihydrostreptomycin, chloramlphenicol, terramycin, or kanamycin, and resistant against aureomycin, achromycin or erythromycin. Almost one-half of the shigella strains isolated was. sensitive to the antibiotics tested. 'iJultiple antibiotic resistant strains were also frequently found in salmonella and. shigella; Strains resistant to three or four antibiotics were predominant among salmonella, and strains resistant to 6 antibiotics were most predominant among shigella. Salmonella and shigella were frequently isolated during summer and autumn.

韓國에서 分離한 Salmonella 및 Shigella의 抗生物質耐性

全燾基,李在九,許東燮,朴秉琦 中央醫學社 1941 中央醫學 Vol.10 No.6

One hundred and fifty-six strains of salmonellae isolated in 1964 and 1965 and 109 strains of shigellae isolated in 1963, 1964 and 1965 in Taegu area were studied on the resistance to chloramphenicol (CM), tetracycline (TC), terramycin (TM) and streptomycin (SM). Antibiotic resistance was tested by the plate dilution method. Briefly, antibiotic was diluted serially_ by doubling dilution method in distilled water and one volume of respective dilution was added to a series of nine volumes of melted nutrient agar. Nutrient agar containing antibiotic was then throughly mixed and poured into Petri dish (20m1) . The final concentration, of antibiotic in nutrient agar ranged from 400-0:78 mcg/ml. One loopful of inoculum containing varyingg numbers of bacilli (500,000; 5,000; and 50 per loop) was streaked on the surface of nutrient agar plate and incubated for 20 hours at 37°C. The results were read by the inhibition of growth of inoculum and the minimum inhibitory concentration of antibiotics to test strains was determined. A strain is considered as resistant if it is capable of growing in the presence of 25 mcg/ml of respective antibiotic. The results obtained were as follows 1. Most of the salmonella strains was inhibited their growth in the presence of 1.56-6.25 mcg/ml of CM, TC or TM in nutrient agar, and 25 rncg/ml of SM. 2. The minimum inhibitory concentration (MIC) of antibiotics to shigellae was distributed widely ranging from less than 0.78 to more than 400 mcg/rnl. However, a majority of strains was inhibited their growth in the presence of 100-400 mcg/ml of CM, TC or TM. Sixty-five strains out of 109 were not inhibited their growth even in the presence of 400 mcg/ml of SM. 3. MIC of antibiotics to test strains varied slightly by the inoculum size used for testing antibiotic resistance. MIC became slightly lowered in most cases when small size of inoculum was used, as compared with the MIC tested with large size of inoculum. - 4. The rate of resistant strains to CM, TC, TM and/or SM among salmonellae was 1.9 to 4. 5 per cents and that of resistant strains among shigellae ranged from 67.9 to 77.1 per cents to four antibitoics. 5. There is a tendency of yearly increase in the rates of resistant strains among salmonellae and shigellae. 6. The multiple antibiotic-resistant strains were only four among 156 strains of salmonellae tested, but those were 82 among 109 strains of shigellae. Seventy-three out of 82 multiple resistant strains of shigellae were resistant to all of four antibiotics.

Prevalence and Drug Resistance of Shigella in Taegu Area of Korea

전도기,박종욱,서성일,조동택,설성용,이유철,Chun, Do-Ki,Park, Jong-Wook,Suh, Seong-Il,Cho, Dong-Taek,Seol, Sung-Yong,Lee, Yoo-Chul The Korea Society for Microbiology 1986 大韓微生物學會誌 Vol.21 No.4

1973년부터 1985년 사이에 대구지방에서 분리된 Shigella는 약 1,200주였는데, 대부분이 Shigella flexneri였고, S. sonnei는 약 20%였으며, S. dysenteriae와 S. boydii는 극히 적었다. 분리균의 95%이상이 chloramphenicol(Cm), tetracycline(Tc), streptomycin(Sm), sulfisomidine(Su), ampicillin(Ap), trimethoprim(Tf) 등의 전부 또는 일부 약제에 내성이었으며, kanamycin, nalidixic acid(Na)와 rifampin(Rf)에 내성인 균주는 소수 있었으나, cephaloridine, gentamicin, amikacin 등에 내성인 균주는 없었다. 1973년에 분리된 균은 약 절반이 약제내성이었으나, 1977년 이후 분리된 균은 95% 이상이 약제내성이었다. 1977년 까지는 Cm, Tc, Sm 및 Su의 4제 내성균이 가장 많았으나 1978년 부터는 Cm, Tc, Sm, Su, Ap 및 Tp의 6제 내성균이 가장 많았다. 약 75%의 균이 그 약제내성을 접합에 의하여 Escherichia coli에 전달하였으므로 이 약제내성은 R plasmid에 의한 것으로 생각되었다. 대다수의 균에 있어서 약제내성 전부를 E. coli에 전달하였으나, Na와 Rf의 내성은 전달되지 않았다. 일부 균주의 약제내성은 E. coli에 전달될 때 분리되는 일이 있었으나, 그 수는 극히 적었다. Shigella의 R Plasmid는 대부분이 비적합성군(incompatibility group) F II에 분류되었으나, 극소수는 B군에 속하였고 군별이 안되는 것도 있었다. Shigella strains isloated in the Teagu area during the period from 1973 to 1985 were studied for species distribution, drug resistance, and R plasmids. Approximately 1,200 strains were isolated during this period, and most of them were classified into Shigella flexneri, S. sonnei occupied less than 20%, and S. dysenteriae and S. boydii were very rarely isolated. More than 95% of them were resistant to one or more of these drugs; chloramphenicol (Cm), tetracycline (Tc), streptomycin (Sm), sulfisomidine (Su), ampicillin (Ap), and trimethoprim (Tp). Strains resistant to kanamycin, nalidixic acid (Na), and rifampin (Rf) were rare, and no strain was resistant to cephaloridine, gentamicin, and amikacin. Approximately half of the isolates were resistant to drugs in 1973, but the rate of resistant strains increased to more than 95% from 1977. Strains resistant to the four drugs (Cm, Tc, Sm, and Su) occupied the majority of resistant strains until 1977, but the most prevalent multiplicity of drug resistance increased to six drugs (Cm, Tc, Sm, Su, Ap, and Tp) from 1978 with the marked increase of Ap- and Tp-resistant strains. Approximately 75% of them transferred resistance to Escherichia coli by conjugation, and the resistance was considered to be mediated by R plasmids. Almost all of them transferred the complete patterns of resistance to drugs except Na and Rf. However, among some strains of recent isolates, small numbers of segregants of transferred resistance were observed. The R plasmids in Shigella were mostly classified into Inc FII, and only small numbers into Inc B. Segregants were in most cases unclassified.

韓國에 있어서의 Salmonella 및 Shigella

全燾基 中央醫學社 1964 中央醫學 Vol.7 No.4

細菌學分野에 있어서의 赤血球凝集反應

全燾基 中央醫學社 1967 中央醫學 Vol.12 No.3