연속측정방법으로 분석한 초음파유화술 전후 고위수차의 변화

임형빈,이종주,최시환,Hyung Bin Lim,Jong Joo Lee,Si Hwan Choi 대한안과학회 2015 대한안과학회지 Vol.56 No.1

Purpose: To analyze the changes of higher order aberration (HOA) measured serially by KR-1W<SUP>Ⓡ wavefront at every second for 10 seconds between, before, and after phacoemulsification and to evaluate the relationships between HOA and the ocular surface indicators (Schirmer test, tear break-up time, superficial punctate keratitis). Methods: Corneal HOA was measured in 47 eyes of 30 patients pre- and postoperatively at 2, 4, 6, and 8 weeks by KR-1W<SUP>Ⓡ using the continuous measurement mode. The patients were divided into 2 groups according to their Schirmer test (above 10 mm or under 10 mm), tear break-up time (above 5 seconds or less than 5 seconds), and superficial punctate keratitis (any keratitis, none) for analysis of relationships between HOA and ocular surface indicators, and we also analyzed the correlation coefficient. Results: Short-term follow up after phacoemulsification revealed that corneal HOA rapidly increased at 2 weeks and recovered to the preoperative level 8 weeks after surgery. Corneal HOA values showed increasing tendency depending on time at preop and 8 weeks after phacoemulsification, and the differences were statistically significant (preop: p < 0.001, 8 weeks: p = 0.027). There were no significant differences of HOA between the 2 groups divided according to their ocular surface indicators, and there were no significant correlations between HOA and ocular surface indicators at any time point. Conclusions: The HOA of the cornea was restored to its preoperative values at 8 weeks after surgery. Preoperative ocular surface indicators are not significantly influenced on postoperative corneal HOA. The surgical factors are more significant in postoperative corneal HOA than preoperative ocular surface indicators. J Korean Ophthalmol Soc 2015;56(1):25-32

위눈꺼풀에 발생한 아포크린샘암종 1예

임형빈,김경남,송계용,이성복,Hyung Bin Lim,Kyoung Nam Kim,Gae Young Song,Sung Bok Lee 대한안과학회 2014 대한안과학회지 Vol.55 No.3

Purpose: To report a case involving an eyelid mass that was diagnosed as apocrine carcinoma. Case summary: A 52-year-old man visited our hospital with a recurrent mass on his right upper eyelid, which had developed 4 years prior. Initially, he received laser therapy at a dermatologic clinic to remove the mass. Two years later, the mass recurred and was excised at another clinic. At the time the patient visited our institution, the lesion had developed into multiple erythematous nodules at the margin of the right upper eyelid. The results of excisional biopsy performed under local anesthesia revealed hidradenoma papilliferum. One month after excision, recurred multiple elevated nodules were found at the margin of the excision, and thus total excision of the mass and reconstruction of the upper eyelid was performed. Biopsy confirmed that the mass was apocrine adenocarcinoma. Five months have passed since the excision and no evidence of recurrence has been observed. Conclusions: Apocrine adenocarcinoma is a malignant tumor of the sweat gland and is rarely found on the eyelid. Apocrine adenocarcinoma should be considered in the differential diagnosis of recurrent eyelid mass at the eyelid margin. J Korean Ophthalmol Soc 2014;55(3):432-436

A Study on Standard MES Model for successful Smart Factory Development: Focused on Small and Medium Sized Manufacturing Companies

Hyung-Bin Lim(임형빈),Joon-Hee Han(한준희),Chae-Soo Kim(김채수),Yonghee Lee(이용희) 대한인간공학회 2020 대한인간공학회 학술대회논문집 Vol.2020 No.10

정상안에서 우세안과 비우세안 사이의 시신경유두주위 빛간섭단층혈관조영 측정치의 대칭성

류천국(Cheon Kuk Ryu),임형빈(Hyung Bin Lim),김정열(Jung Yeul Kim) 대한안과학회 2021 대한안과학회지 Vol.62 No.11

목적: 주시안과 비주시안이 빛간섭단층촬영 및 시신경유두주위 빛간섭단층혈관조영술 측정치에 미치는 영향을 분석해보고자 하였다. 대상과 방법: 안과 질환이 없는 성인을 대상으로 촬영한 빛간섭단층촬영 및 빛간섭단층혈관조영술을 분석하였다. ‘Hole-in-the-card test’를 시행하여 주시안을 확인하였다. 시신경유두주위에 4.5 x 4.5 mm scan을 시행하여 시신경유두주위 관류밀도 및 플럭스 지수를 측정하였으며, 중심황반두께 및 신경절세포층 및 내망상층, 망막신경섬유층 두께 역시 측정하였다. 주시안과 비주시안의 빛간섭단층촬영, 빛간섭단층혈관조영술 측정값을 비교 분석하였다. 결과: 42명 84안이 포함되었다. 대상군의 평균 나이는 27.3 ± 5.63세였으며, 주시안은 우안 28안(66.7%), 좌안이 14안(33.3%)이었다. 빛간섭단층촬영검사에서 주시안과 비주시안 간의 중심황반두께(260.00 ± 14.16 μm, 258.71 ± 15.18 μm, p=0.183), 신경절세포층 및내망상층 복합체두께(82.02 ± 5.07 μm, 82.43 ± 5.60 μm, p=0.460), 망막신경섬유층 두께(99.36 ± 9.27 μm, 97.90 ± 9.46 μm, p=0.091)에 유의한 차이가 없었다. 또한, 빛간섭단층혈관조영술검사의 시신경 주위 표층모세혈관망의 관류 밀도(44.62 ± 5.25%, 45.60 ± 2.27%, p=0.221), 플럭스 지수(0.455 ± 0.020, 0.449 ± 0.028, p=0.060)에서도 통계적인 차이는 확인되지 않았다. 결론: 빛간섭단층촬영 및 빛간섭단층혈관조영술의 측정치는 주시안과 비주시안 사이에 유의한 차이를 보이지 않았으며 따라서 주시안을 확인하는 데 이용할 수 있는 인자로서의 의미는 찾을 수 없었다. Purpose: To assess whether optical coherence tomography (OCT) measurements and peripapillary microvascular parameters measured via optical coherence tomography angiography (OCTA) were similar between the dominant and non-dominant eyes of normal subjects. Methods: We retrospectively analyzed spectral domain OCT and OCTA data on healthy Koreans. The “hole-in-the-card” technique was used to determine ocular dominance. The perfusion density (PD) and flux index (FI) of the peripapillary 4.5 × 4.5-mm area were measured via OCTA. Central macular, peripapillary retinal nerve fiber layer, and macular ganglion cell-inner plexiform layer thicknesses were measured with the aid of spectral-domain OCT. The OCT and OCTA data of dominant and non-dominant eyes were compared. Results: A total of 84 eyes of 42 healthy subjects were analyzed. The average age was 27.3 ± 5.63 years. Twenty-eight subjects (66.7%) were right eye-dominant and 14 (33.3%) left eye-dominant. None of the central macular (260.00 ± 14.16 μm, 258.71 ± 15.18 μm, p = 0.183), macular ganglion cell-inner plexiform layer (82.02 ± 5.07 μm, 82.43 ± 5.60 μm, p = 0.460), or peripapillary retinal nerve fiber layer thickness (99.36 ± 9.27 μm, 97.90 ± 9.46 μm, p = 0.091) differed between the eyes; neither did any OCTA-assessed microvascular parameter. Conclusions: No OCT or OCTA parameter differed between dominant and non-dominant eyes. No parameter identified ocular dominance.

결핵성 뇌막염환자에서 발생한 눈벌림 마비

성재연(Jae Yun Sung),임형빈(Hyung Bin Lim),이연희(Yeon-Hee Lee) 대한검안학회 2016 Annals of optometry and contact lens Vol.15 No.4

Purpose: We report a case of divergence paralysis associated with tuberculous meningitis. Case summary: A 28 year old man was diagnosed with tuberculous meningitis based on clinical manifestation, cerebrospinal fluid analysis and brain magnetic resonance imaging and was administered anti-tuberculous medication. Four days later, diplopia at distance occurred and the patient was referred to ophthalmologic clinic. Eye motility examination revealed comitant esotropia of 10 prism diopters (PD) at distance and esophoria of 2 PD at near. There was no limitation of eye movement. He was diagnosed with divergence paralysis. 1 week later, esotropia and diplopia are completely resolved. Conclusions: Divergence paralysis associated to tuberculous meningitis is very rare and has not been reported previously. The authors believe this is a case of divergence paralysis associated to tuberculous meningitis and report it as a rare case.

성공적인 코경유 눈물주머니코안연결술의 예측인자

신일환(Il Hwan Shin),임형빈(Hyung Bin Lim),이종주(Jong Joo Lee),이성복(Sung Bok Lee) 대한안과학회 2015 대한안과학회지 Vol.56 No.11

Purpose: To evaluate the factors useful for predicting the surgical outcome of endonasal dacryocystorhinostomy. Methods: This retrospective observational study included 117 eyes of 94 patients with nasolacrimal duct obstruction who under-went endonasal dacryocystorhinostomy and were followed up for more than 6 months. Factors associated with successful sur-gery were analyzed based on the preoperative and intraoperative factors and postoperative clinical features. Preoperative fac-tors such as age, gender, laterality, presence or absence of hypertension, and diabetes were analyzed. Intraoperative factors such as use of triamcinolone, removal of uncinate process or middle turbinate during surgery, and location of the sac were analyzed. The postoperative clinical features including high tear meniscus, no intranasal silicone tube movement, and no air re-flux feeling were each given a score of 1. Based on aggregate score, the patients were divided into 2 groups, the high score and low score groups and analyzed accordingly. Results: The success rate was 91.5%. Patients with diabetes showed a significantly low success rate (73.3%, p = 0.007). In pa-tients with high tear meniscus at 3, 6, and 9 weeks after surgery, the success rate was significantly low (76.9%, 81.8% and 75.0%; p = 0.003, p = 0.029 and p = 0.002, respectively). The low score group at 3 and 6 weeks after surgery showed a sig-nificantly high success rate (100% and 95.9%; p < 0.001 and p = 0.023, respectively). Conclusions: Besides preoperative and intraoperative factors, the early postoperative clinical features are important for predict-ing the success of the surgery. If tear meniscus is high and there is no intranasal silicone tube movement and air reflux from the punctum in the early stages after surgery, more active management from the initial treatment is needed. 목적: 코경유 눈물주머니코안연결술의 수술 결과를 예측할 수 있는 인자를 찾아보고자 하였다. 대상과 방법: 코눈물관막힘 진단하에 코경유 눈물주머니코안연결술을 시행하고 6개월 이상 경과를 관찰한 94명 117안을 대상으로 후향적 분석을 시행하였다. 수술 성공과 연관이 있는 요인을 술 전 요인, 술 중 요인, 술 후 임상 소견으로 분석하였다. 술 전 요인으로 나이, 성별, 좌우안, 고혈압과 당뇨 유무를 분석하였고, 술 중 요인으로 트리암시놀론 사용 여부, 술 중 구상돌기나 중간코선반 제거 여부, 눈물주머니의 위치를 분석하였다. 술 후 임상 소견으로 눈물띠가 높은 경우, 코안 실리콘관 움직임이 없는 경우, 공기역류를 느끼지 못하는 경우를 각각 1점으로 하여, 합산 점수가 낮은 군과 높은 군으로 나누어 분석하였다. 결과: 수술 성공률은 91.5%였다. 당뇨가 있는 경우 수술 성공률이 73.3%로 유의하게 낮았다( p =0.007). 술 후 3, 6, 9주째에 높은 눈물 띠를 보인 경우 수술 성공률이 76.9%, 81.8%, 75.0%로 유의하게 낮았다( p =0.003, p =0.029, p =0.002). 술 후 3, 6주째에 낮은 점수군 은 수술 성공률이 100%, 95.9%로 유의하게 높았다( p <0.001, p =0.023). 결론: 수술 성공을 예측하기 위하여 술 전, 술 중 요인에 대한 평가뿐만 아니라, 술 후 임상소견에 대한 평가도 유용하게 사용될 수 있을 것으로 생각된다. 수술 후 초기에 눈물띠가 높고, 코안 실리콘관의 움직임, 공기역류가 관찰되지 않는다면 더 적극적인 관리가 필요할 것으로 생각된다.