모링가의 항산화, 항노화, 면역조절, 미백 효과

임완택,홍창의,유수연 한국식품영양과학회 2024 한국식품영양과학회지 Vol.53 No.2

모링가 제품군 네 가지(오일, 발효환, 분말, 차)의 DPPH 라디칼 소거능을 측정한 결과, 모든 제품군에서 농도 의존적으로 높은 항산화능이 나타났으며, SOD 유사 활성을 측정한 결과 모링가 발효환 처리군에서 활성도가 증가하였다. 미백 효과를 알아보기 위하여 티로시나아제 억제 활성을 알아본 결과, 오일을 제외한 모든 제품 처리군에서 억제 활성이 나타났다. 또한 항노화 효과를 알아보았는데, 이 역시 오일을 제외한 모든 모링가 제품 처리군에서 우수한 엘라스타제 저해 효과를 나타냈다. 마지막으로 모링가 제품군 중 발효환, 분말, 차가 NO 생성 및 TNF-α 분비를 억제하는 것을 보여주어 항염증 효과를 입증하였다. This study examined the antioxidant, anti-aging, immunomodulatory, and whitening effects of four Moringa oleifera products: oil, fermented capsule, powder, and tea. All four products scavenged free radicals, but only the fermented capsule boosted the superoxide dismutase activity. The fermented capsule, powder, and tea also reduced the elastase and tyrosinase activity, suggesting that M. oleifera has anti-aging and whitening effects. In addition, all products except for the oil had immunomodulatory effects by reducing nitric oxide and tumor necrosis factor-alpha production. On the other hand, interleukin-6 secretion did not change. In conclusion, these findings suggest that M. oleifera has the potential to protect against cell damage, improve skin health, and modulate the immune system.

민감도 해석의 볼 베어링 상수 규명에의 이용

임완택,이종원,김광준 대한기계학회 1988 대한기계학회 춘추학술대회 Vol.- No.-

Tension Identification in Belt Driving Systems by Analyzing the Flexural Vibration

임완택,김광준 대한기계학회 1993 대한기계학회 춘추학술대회 Vol.- No.-

Nocardioides ginsengisegetis sp. nov., Isolated from Soil of a Ginseng Field

임완택,김세영,Qing-Mei Liu,Jung-Eun Yang,이성택,이태후 한국미생물학회 2010 The journal of microbiology Vol.48 No.5

A Gram-positive, rod-shaped, non-spore-forming bacterium (Gsoil 485T) was isolated from the soil of a ginseng field located in Pocheon province in South Korea. This bacterium was characterized in order to determine its taxonomic position by using the polyphasic approach. On the basis of 16S rRNA gene sequence similarity, strain Gsoil 485T was shown to belong to the family Nocardioidaceae and related to Nocardioides koreensis (96.8% 16S rRNA gene sequence similarity), Nocardioides basaltis (96.7%), Nocardioides salarius (96.7%), and Nocardioides sediminis (96.5%). The sequence similarity with other species that had validly published names within the genus Nocardioides was less than 96.4%. Strain Gsoil 485T was characterized chemotaxonomically as having LL-2,6-diaminopimelic acid in a cell-wall peptidoglycan, MK-8(H4) as the predominant menaquinone, and iso-C16:0, C18:1 ω9c as the major fatty acids. The G+C content of genomic DNA was 71.6 mol%. The chemotaxonomic properties and phenotypic characteristics supported the affiliation of strain Gsoil 485T to the genus Nocardioides. The results of both physiological and biochemical tests allowed for genotypic differentiation of strain Gsoil 485T from the recognized Nocardioides species. Therefore, strain Gsoil 485T is considered to represent the novel species, for which the name Nocardioides ginsengisegetis sp. nov. is proposed, with the type strain Gsoil 485T (KACC 14269T =KCTC 19469T=DSM 21349T).

Panacagrimonas perspica gen. nov., sp. nov., a Novel Member of Gammaproteobacteria Isolated from Soil of a Ginseng Field

임완택,Qing-Mei Liu,양정은,김민석,김세영,이성택,이태후 한국미생물학회 2010 The journal of microbiology Vol.48 No.2

A taxonomic study was carried out on Gsoil 142T, a bacterial strain isolated from the soil collected in a ginseng field in Pocheon province, South Korea. Comparative 16S rRNA gene sequence studies showed a clear affiliation of this bacterium to the Gammaproteobacteria, and it was most closely related to Hydrocarboniphaga effusa ATCC BAA 332T (94.4%, 16S rRNA gene sequence similarity), Nevskia ramosa DSM 11499T (94.1%) and Alkanibacter difficilis MN154.3T (92.0%). Strain Gsoil 142T was a Gram-negative, strictly aerobic, motile, and rod-shaped bacterium. The G+C content of the genomic DNA was 69.9% and predominant ubiquinone was Q-8. Major fatty acids were summed feature 8 (C18:1 ω7c and/or ω6c, 36.3%),summed feature 3 (iso-C15:0 2-OH and/or C16:1 ω7c, 20.6%) and C16:0 (17.4%). The major polar lipids detected in strain Gsoil 142T were phosphatidylethanolamine, phosphatidylglycerol, diphosphatidylglycerol, and an unknown glycolipid. On the basis of polyphasic evidence, it is proposed that strain Gsoil 142T should be placed in a novel genus and species, for which the name Panacagrimonas perspica gen. nov., sp. nov. is proposed. The type strain is Gsoil 142T (=KCTC 12982T =LMG 23239T).

HILS 시험 결과 분석을 위한 하이브리드 신경망 개발

임완택(Wantaik Lim),오민택(Mintack Oh),서영식(Yeongsik Seo) 한국자동차공학회 2021 한국자동차공학회 부문종합 학술대회 Vol.2021 No.6

As vehicle technology rapidly changes to the form of autonomous driving and mobility and the system is complicated, simulation verification technology that combines virtual vehicle environments has been highlighted. For braking HILS system, simulation verification based on these virtual environments is possible. However, even though the evaluation is performed automatically, the resulting judgment must be verified manually by the test engineer. To solve these problems, we recently used artificial intelligence techniques that have been in the spotlight and proposed a novel hybrid deep learning model with the best validation accuracy. We analyzed the learning performance of the proposed model and demonstrated that AI judgment results are consistent by applying it to the actual HILS test results.

Control & Communication 상에서의 PLG 고장허용 통신 시스템 구현

임완택(Wan-Taek Lim),김응석(Eung-Seok Kim),양해원(Hai-Won Yang) 대한전기학회 2002 대한전기학회 학술대회 논문집 Vol.2002 No.7

Parabacteroides chongii sp. nov., isolated from blood of a patient with peritonitis

김현수,임완택,김명숙,김도균,서영희,용동은,정석훈,이경원 한국미생물학회 2018 The journal of microbiology Vol.56 No.10

An obligate anaerobic, Gram-reaction-negative, non-sporeforming, non-motile, rod shaped bacterium designated YMC B3181T was isolated from the blood of a patient with peritonitis. Strain B3181T grew at 20 to 40°C with optimum growth at 37°C. 16S rRNA gene sequence similarity showed strain B3181T belongs to the genus Parabacteroides and is closely related to Parabacteroides faecis 157T (97.3%), Parabacteroides gordonii MS-1T (96.6%), and Parabacteroides goldsteinii DSM 19448T (95.7%). The G + C content of the genomic DNA was 42.3 mol%. The major cellular fatty acids were anteiso- C15:0 and iso-C17:0 3-OH, and the predominant respiratory quinones were MK-9 and MK-10 menaquinones. Genomic and chemotaxonomic data supported affiliation of B3181T with the genus Parabacteroides. Strain B3181T was phylogenetically and phenotypically different from recognized species of the genus Parabacteroides. Accordingly, this isolate belongs to a novel species for which the name Parabacteroides chongii sp. nov. (type strain YMC B3181T = LMG 30065T = KACC 19034T) is proposed.

한국산 겨우살이의 항염증 효과

홍창의,임완택,유수연,Hong, Chang-Eui,Lim, Wantaek,Lyu, Su-Yun 대한화장품학회 2022 대한화장품학회지 Vol.48 No.3

본 연구에서는 한국산 겨우살이 (Viscum album L. var. coloratum)이 아토피 피부염과 관련된 염증성 사이토카인에 영향을 미치는지 여부를 알아보았다. 실험에는 헥산, 부탄올, 에틸아세테이트, 메틸렌클로라이드, 총 4 가지 분획물을 사용하였으며, RAW264.7 마우스 대식세포와 RBL-2H3 렛트 호중구를 이용하여 염증성 마커를 연구하였다. 실험 결과 에틸아세테이트 분획이 tumor necrosis factor alpha (TNF-α), interleukin(IL)-6, IL-4의 mRNA 발현 및 단백질 분비량을 감소시켰으나, 헥산 분획은 뚜렷한 효능이 없었다. 또한 부탄올 분획은 IL-4, IL-6의 mRNA 발현을 감소시켰고, 메틸렌클로라이드 분획은 IL-4와 TNF-α의 mRNA 발현을 감소시켰다. 결과적으로 한국산 겨우살이(V. album var. coloratum)가 아토피 피부염과 관련된 사이토카인 분비를 억제시켜 항염증 효과를 나타낼 수 있으므로, 이와 관련된 기능성 화장품 개발이 가능할 것으로 사료된다. In this study, we investigated whether Korean mistletoe (Viscum album L. var. coloratum) has anti-inflammatory effects that play key roles in the regulation of pathological mechanism of atopic dermatitis (AD). Four kinds of fractions, hexane (HX), ethyl acetate (EA), butanol (BU), and methylene chloride (MC), were used and RAW264.7 mouse macrophages and RBL-2H3 rat basophils were used to measure various inflammatory markers. EA significantly decreased mRNA expression and protein secretion levels of tumor necrosis factor alpha (TNF-α), interleukin (IL)-6, and IL-4 but HX did not affect these markers. In addition, BU decreased mRNA expressions of IL-4 and IL-6 whereas MC decreased IL-6 and TNF-α mRNA expressions. As a result, Korean mistletoe can show anti-inflammatory effects by inhibiting the secretion of cytokines related to AD, so it is thought that it will be possible to develop functional cosmetics related to this.

Niabella ginsenosidivorans sp. nov., isolated from compost

이권정,임완택,김동운,Qing Mei Liu,김수기 한국미생물학회 2015 The journal of microbiology Vol.53 No.11

A Gram-reaction negative, strictly aerobic, non-motile, orange colored, and rod-shaped bacterium (designated BS26T) isolated from compost, was characterized by a polyphasic approach to clarify its taxonomic position. Strain BS26T was observed to grow optimally at 25–30°C and at pH 7.0 on R2A and nutrient media. Strain BS26T showed β-glucosidase activity that was responsible for its ability to transform ginsenoside Rb1 (one of the active components of ginseng) to ginsenoside compound-K (C-K). Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain BS26T belongs to the genus Niabella of family Chitinophagaceae and was most closely related to Niabella soli DSM 19437T (94.5% similarity), N. yanshanensis CCBAU 05354T (94.3%), and N. aurantiaca DSM 17617T (93.8%). The G+C content of genomic DNA was 47.3 mol%. Chemotaxonomic data [predominant isoprenoid quinone-MK-7, major fatty acids–iso-C15:0, iso-C15:1 G, iso-C17:0 3-OH, and summed feature 3 (comprising C16:1 ω7c and/or C16:1 ω6c)] supported the affiliation of strain BS26T to the genus Niabella. However, strain BS26T could be differentiated genotypically and phenotypically from the recognized species of the genus Niabella. The novel isolate therefore represents a novel species, for which the name Niabella ginsenosidivorans sp. nov. is proposed, with the type strain BS26T (=KACC 16620T =JCM 18199T).