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김지영(Jee young Kim),신가영(Ka yeong Shin),임보영(Bo young Lim),안지영(Ji Young Ahn) 한국산업경영학회 2015 경영연구 Vol.30 No.2
전통적으로 경력이란 한 조직 안에서 위계서열상의 진보를 의미하는 개념이었으나 고용안정성이 저하되어 이직과 해고가 빈번한 오늘날의 기업환경 하에서는 새로운 경력 개념이 필요해졌다. 이에 다중경력은 개인의 심리적인 성공에 초점을 맞춘 개념으로 자기 주도적 학습을 통해 조직의 심리적, 물리적 이동을 통해 형성하는 경력을 의미한다. 이러한 다중경력은 변화하는 환경에 적합한 경력의 형태이나 특정 조직에 국한되지 않는 무경계성과 조직의 성공보다 개인의 심리적 성공을 추구하는 속성으로 조직몰입을 약화시킬 수 있다. 따라서 본 연구에서는 다중경력과 조직몰입의 관계를 실증적으로 검증하고 또한 다중경력과 조직몰입의 부정적 관계를 완화시킬 수 있는 조직 내 변인으로서 조직신뢰와 조직문화의 조절 효과를 입증하고자 하였다. 한국직업능력개발원에서 2009년 실시한 인적자본 기업패널(HCCP)을 사용하여 연구를 진행한 결과 다중경력은 조직몰입에 부정적인 영향을 주며 조직신뢰가 높은 조직에서는 다중경력이 조직몰입에 갖는 부정적인 효과가 조직신뢰에 의해 완화될 수 있음을 보였다. 그러나 개발문화의 경우 조절효과를 발견하지 못했다. This research examined the conceptualization of “multiple career” and empirically tested its effect on organizational commitment. While a traditional career implies advancement in a hierarchical organization, employee career could be established in multiple organizations under dynamic environment where a new career should be needed. Multiple career could be developed by employee self-directed learning and also focuses on psychological success beyond the organizational boundary. Using the HCCP data, we found that multiple career is negatively related to organizational commitment. Moreover, we also tested that its negative effect of multiple career on organizational commitment can be mitigated by a high level of organizational trust and developmentoriented culture. It showed that only organizational trust moderated the negative effect of multiple career on organizational commitment.
한국인에서 혈소판 당단백 Ⅱb/Ⅲa 유전자 다형성과 관동맥 성형술 후 재 협착과의 관계
이민수,이정우,김보영,임대승,강정아,김정희,김윤철,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2
Platelet aggregation is the final pathway of acute coronary syndrome such as acute myocardial infarction and unstable angina. Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and yon Willebrand factor and it plays an important role in platelet aggregation and in the pathogenesis of acute coronary syndrome. It is known that polymorphism of the gene that encoding platelet glycoprotein IIb/IIIa(PI^A1/A2) is strongly related to acute coronary syndrome in Caucasian, but not in Koreans. We investigated relationship between platelet glycoprotein llb/Illa gene polymorphism and restenosis of coronary artery after angioplasty in Koreans. Total 371 patients(M=251. F=120) were enrolled. Angioplasty group comprised 143 patients who underwent coronary angioplasty, and in the angioplasty group, restenosis group comprised with the 65 patients who had restenotic lesion over 50% of luminal diameter in follow-up coronary angiography. Normal group comprised 153 patients who had no significant angiographic lesion and variant angina group comprised 75 patients who were positive in ergonovine test. Genomic DNA was extracted from peripheral arterial blood. To determine the frequency of P1^A1/A2 genotype, polymerase chain reaction(PCR) was done and the product was restricted with Mspl. 3%. agarrose gel electrophoresis showed restriction fragment length polymorphism. Clinical profile and risk factor were also reviewed. Among all 371 patients of study group, genotype of only one patients in restenosis group if is proven to be PI^A1/A2 heterozygote. All patients of normal study group, no restenosis group, and the other patients in restenosis group have an PI^A1 homozygote genotype. In our study, platelet glycoprotein IIb/Illa polymorphism has no relationship with restenosis of the coronary artery after angioplasty in Koreans. But the genotypic frequency of platelet glycoprotein IIb/IIIa gene polymorphism in Koreans is concordant with that of previous studies.
김윤철,이정우,김보영,강정아,임대승,이민수,김정희,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1
Coronary stent implacement is known as an effective treatment in the intimal dissection after percutaneous transluminal coronary angioplasty and the prevention of restenosis. However, In-stent restenosis still remains a major concern in clinical stenting. The stents were placed in 103 patients from July 1996 to March 1999 and performed follow-up coronary angiograms in 59(57.3%) patients. To identify the clinical, angiographic and procedurerelated variables 'which predict late restenosis within the stented artery, 59 patients(58.3±9.9, M:F= 41:18) were studied. The clinical characteristics of the patients were stable angina in 23(39.0%), unstable angina in 14(23.7%), acute myocardial infarction in 21(35.6%) and old myocardial infarction in 1(1.7%). Coronary stenting was performed in 1 patient(1.7%) for primary lesion, 50 patients(84.7%) for suboptimal results after PTCA, 6 patients(10.2%) for bail-out procedure, and 2 patients(3.4%) for restenotic lesions. All patients were treated with aspirin and ticlopidinc. The follow-up angiograms were obtained at 7±4 months. The overall in-stent restenosis rate was 27.1%. The coronary angiographic findings were 32 single vessel(54.2%), 19 two vessel(32.2%) and 8 three vessel disease(13.6%). The angiographic morphological characteristics were type A in 33(55.9%), type B in 14(23.7%), type C in 12(20. 3%) cases. Variables of 16 patients with restenosis were compared with those of 43 patients without restenosis. Previously known predictors for in-stent restenosis were multiple stenting, stenting for restenotic lesions, residual stenosis after stenting, stenting for total occlusion lesions, reference diameter, balloon to vessel ratio, acute gain and minimal luminal diameter after procedure, design and characteristics of stents, ostial lesion of aorta, high pressure method for stenting, lesion length, diabetes mellitus, size of artheroma, saphenous vein grafts, ulcerlating lesions and calcified lesions. In this study, Reference diameter before stenting(2.43±0.54mm vs. 2.88±0.65mm, p=0.016) and balloon-to-artery ratio(1.28±0.26 vs. 1.11±0.18, p=0.006) were predictors for in-stent restenosis. 1) The overall in-stent restenosis rate was 27.1%. 2) In the analysis of predictors for in-stent restenosis, there was no significant differences in clinical, angiographic factors between group with restenosis and without restenosis. But, Only reference diameter before stenting and balloon-toartery ratio were predictors of late in-stent restenosis. In conclusion, stenting is effective revascularisation method for selected patients with ischemic heart disease, and to minimize in-stent restenosis rate, stent implanting is achieved in a large vessel on the basis of an artery-to-stnet ration of 1:1, if possible.