비개흉 심근 경색 동물모델을 이용한 심근 경색의 자기공명영상에 관한 연구

임명관,박재형,이활,정진욱,이동수,정준기,최영희 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.11

뇌의 T2강조 자기공명영상에서의 자화전이 : 정상및 병적 뇌조직에서의 자화전이율

임명관 대한영상의학회 1998 대한영상의학회지 Vol.39 No.1

Purpose : To evaluate the magnetization transfer ratio(MTR) of various normal structures and pathologic lesions, as seen on magnetization transfer T2-weighted images (MT+T2WI). Materials and Methods : In ten normal volunteers, T2-weighted images without MT (MT-T2WI) and with MT(MT+T2WI) were obtained. Off-set pulses used in MT+T2WI were 400, 600, 1000, 1500, and 2000Hz. In 60 clinical cases infarction(n=10), brain tumors(n=5), traumatic hematomas(n=5), other hematomas(n=3) vascular malformation(n=2) white matter disease(n=2) normal(n=31) and others(n=2), both MT-T2WI and MT+T2WI images were obtained using an off-set pulse of 600 Hz. In all volunteers and patients, MTR in various normal brain parenchyma and abnormal areas was measured. Results : The MTRs of white and gray matter were 48% and 45% respectively at 400 Hz, 26% and 22% at 600Hz, 12% and 11% of 1000Hz, 10% and 9% 1500HZ, and 9% and 8% at 2000Hz of RF. The MTR of CSF was 43% at 400 Hz of off-resonance RF, while the contrast resolution of T2WI was poor. An off-resonance of 600Hz appeared to be the optimal frequency. In diseased areas, MTRs varied but were usually similar to or lower than those of brain parenchyma. Conclusion : The optimal off-resonance RF on MT+T2WI appears to be 600 Hz for relatively high MTR of brain parenchyma and low MTR of CSF, in which MTRs of white and gray matter were 26% and 22%, respectively, of 600Hz off-set pulse. The MTRs of cerebral lesions varied and further studies of various cerebral lesions are needed.

특발성 폐 섬유화증과 교원병의 폐 침범의 비교 : 고해상 CT 소견

임명관 대한영상의학회 1993 대한영상의학회지 Vol.29 No.6

Both idiopathic pulmonary fibrosis (IPF) and pulmonary involvement of collagen vascular disease (CVD) are well known cause of diffuse interstitial lung disease which lead to fibrosis and honeycombing. We analyzed HRCT findings of 33 patients with IPT and 14 patients with CVD in terms of predominant pattern, site of involvement, mediastinal lymph node enlargement, pleural change and pulmonary volume loss. Criteria of mediastinal lymph node enlargement and pleural thickening were 15mm in long diameter and 3mm, respectively. Volume loss of the lung was measured by using hilar height ratio (apex to hilum/hilum to diaphragmatic dome). Mean age was 61 years for IPE and 46 years for CVD and male : female ratio was 27: 6, 4:10, respectively. Predominant HRCT pattern was honeycombing for IPE (63%), and ground-glass opacity for CVD (66%) (p=0.001) Predominantly subpleural involvement was seen in 90% for IPE and 74% for CVD Mediastinal lymph node enlargement was seen in 47% of the patient with IPE and 14% with CVD (p=0.004). Pleural thickening was seen in 97% of the patients with IPE and 42% with CVD (p=0.002). Pleural effusion was seen in 10% of the patients with IPE and 36% with CVD (p=0.009). Hilar height ratio of more than 1.5 was seen in 84% of the patients with IPE and 29% with CVD. In conclusion, our study shows that patients with IPF are prone to have more progressed stage of pulmonary fibrosis than the patients with CVD on HRCT.

타액선에 생긴 선양낭포암의 신전이 : 2례 보고

임명관 대한영상의학회 1992 대한영상의학회지 Vol.28 No.5

Adenoid cystic carcinoma of the major salivary gland is a relatively rare tumor which is well known for its high local recurrence rate and frequent distant metastasis. Metastasis of this tumor to kidney has not been reported previously to our knowledge. We report two cases of renal netastasis from adenoid cystic carcmoma of the salivary gland.

혈관내 삽입된 나선형 금속스텐트가 혈관구조에 미치는 영향에 관한 실험적 연구

임명관 대한영상의학회 1996 대한영상의학회지 Vol.34 No.6

Purpose : The purpose of this study was to evaluate basic experimental data for the clinical application of a self-expandable stainless steel intravascular Hanaro spiral stent Materials and Methods : For evaluation of the physical properties of the Hanaro stent, hoop strength, radioopacity, longitudinal flexibility, and foreshortening were measured. Twelve intravascular Hanaro spiral stents were placed in the infrarenal abdominal aorta (n=6) and comon iliac artery (n=6) in six mongrel dogs. Angiography and light microscopic examination were performed after one, two and eight months of placement of the stents. Results : The stent had good radioopacity and was deployed with minimal foreshortening. Hoop strength of a 6mm-interval bend was found to be superior to that of 8mm- and10mm-bend stent. On angiography the patency rate and thrombosis rate were 100% and 0% in the abdominal aorta and50% and 50% in the common iliac artery, respectively. Minimal corrosion was seen in all stents, and they appeared to be biocompatible. The stent wires were covered with well-developed neointima which after one month had mostly fibroblast and collagen tissue; the thickness of the neointima increased gradually during a period of eight months. At the end of that period, collagen fibres in the neointima were denser and showed a more paralled configuration than at one month. Conclusion : The Hanaro stent has good physical properties and also has a high patency rate, and good biocompatibilities. The stent may therefore be reliably and safely deployed in the human vascular system.

고로슬래그의 분말도 및 재생잔골재 치환율에 따른 모르타르의 특성에 관한 연구

임명관,한다희,정상진 단국대 부설 리모델링연구소 2008 리모델링 연구소 논문집 Vol.6 No.1

Furnace slag powder used currently in Korea needs to add special functions in response to the increase of large-scale projects. In addition, it is advantageous in that it has a lower hydration heat emission rate than ordinary Portland cement and improves properies such as the inhibition of alkali aggregate reaction, watertightness, salt proofness, seawater resistance and chemical reslstance. However, furnace slag powder is not self-hardening, and requires activators such as alkali for hydration. Accordingly, if recycled fine aggregate, from which calcíum hydroxide is generated, and furnace slag, which requires alkali stimulation, are used together they play mutually complementary roles, so we expect to use the mixture as a resource-recycling construction material. Thus the present study purposed to examine the properties and characteristics of furnace slag powder and recycled aggregate, to manufacture recycled fine aggregate mortar using furnace slag and analyze its performance based on the results of an experiment, to provide materials on mortar using furnace slag as a cement additive and recycled fine aggregate as a substitute of aggregate, and ultimately to provide basic materials on the manufacturing of resource-recycled construction materials using binder and fine aggregate as recycled resources.

원자력 발전소 3호기용 국산핵연료 1차 시제품의 원자로 내 연소결과 보고서

임명관,엄두영 한국원자력학회 1986 Nuclear Engineering and Technology Vol.18 No.2

고로슬래그의 분말도 및 순환골재 치환율에 따른 콘크리트의 강도 및 내구적 특성에 관한 연구

임명관,정상진,박무영 한국건축시공학회 2007 한국건축시공학회지 Vol.7 No.4

Furnace slag powder used currently in Korea needs to add special functions in response to the increase of large-scale projects. In addition, it is advantageous in that it has a lower hydration heat emission rate than ordinary Portland cement and improves properties such as the inhibition of alkali aggregate reaction, watertightness, salt proofness, seawater resistance and chemical resistance. However, furnace slag powder is not self-hardening, and requires activators such as alkali for hydration. Accordingly, if recycled fine aggregate, from which calcium hydroxide is generated, and furnace slag, which requires alkali stimulation, are used together they play mutually complementary roles, so we expect to use the mixture as a resource-recycling construction material. Thus the present study purposed to examine the properties and characteristics of furnace slag powder and recycled aggregate, to manufacture recycled fine aggregate concrete using furnace slag and analyze its performance based on the results of an experiment, to provide materials on concrete using furnace slag as a cement additive and recycled fine aggregate as a substitute of aggregate, and ultimately to provide basic materials on the manufacturing of resource-recycled construction materials using binder and fine aggregate as recycled resources.

능동적 운동과 수동적 운동의 기능적 자기공명영상에서의 비교

임명관,김형진,조영국,서창해,Im, Myeong-Gwan,Kim, Hyeong-Jin,Jo, Yeong-Guk,Seo, Chang-Hae 대한영상의학회 2002 대한영상의학회지 Vol.46 No.5

목적: 기능적 자기공명영상(functional magnetic resonance imaging:이하 fMRI로 약함)을 이용하여 본인이 자발적으로 움직이는 능동적 운동과 남이 하는 대로 움직이는 수동적 운동에서 fMRI 소견의 차이를 알아보고자 하였다. 대상과 방법: 건강한 7명의 자원자가 대상이었으며 모두 오른손잡이 였다. 각 자원자에서 좌측및 우측 엄지 손가락을 자발적,능동적으로 움직이게 한 후 fMRI를 얻었고, 그 후에 같은 손가락을 끈으로 묶고 자발적 운동과 같은 시간 간격 및 강도로 수동적 운동을 시행하였다. 1.5TMR영상기기에서 EPI(echo planar image)-BOLD(blood oxygen level dependant)기법을 이용하여 기능적 영상을 얻었으며, 영상 후처리(postprocessing of image)는 SPM 분석 프로그램을 사용하였고 활성화 신호의 유의수준은 p <0.01 또는 p <0.001로 하였다. 결과:능동적 운동의 경우 7명의 14예 모두에서 반대측 대뇌의 일차 감각-운동중추(primary sensory-motor cortex)와 부 운동중추(supplementary motor cortex)의 강한 활성화를 볼 수있었으며, 동측의 일차 감각-운동중추가 활성화된 경우가 12예, 동측의 부 운동중추가 활성화된 예가 11예 있었다. 이에 반해 수동적 운동의 경우 반대측 대뇌의 일차 감각-운동중추의 활성화 화소(pixel)의 개수나 신호강도가 자발적 운동보다 훨씬 낮았으며 부 운동중추의 활성화는 3예에서만 보였다. 그리고 동측의 감각운동중추나 부 운동중추의 활성화는 한 예에서도 보이지 않았다. 결론: fMRI에서 수동적 운동의 경우 능동적 운동보다 활성화 화소의 개수나 신호강도가 적었 고 또한 부 운동중추의 활성화가 거의 보이지 않았으며, 이와 같은 결과는 향후 의식이 없는 환자나 동물실험에서 기능적 자기공명영상 적용의 기초자료가 될 것으로 사료된다. Purpose: To compare functional MR imaging of the motor cortex during active and passive movement. Materials and Methods: Seven healthy, right-handed volunteers (M:F=6:1; age:25-30 years) were included in this study. A 1.5-T whole body scanner and the multislice EPI BOLD method were used. The motor paradigm was flexion-extension of a thumb against rest. In the active motion task, the thumb was flexed voluntarily once a second, while in the passive task, it was tied with a thread and pulled to flex and extend passively at the same interval and with the same intensity as in the active task. For image postprocessing, an SPM 96 program was used. The sites, numbers, and signal intensity of the activated pixels were determined, and the threshold for significance was set at p<0.001 to p<0.01. Results: In the active motion task, strong activation at the contralateral side of the primary sensorimotor cortex and supplementary motor cortex occurred in all 14 examples in all seven volunteers. Additionally, the ipsilateral primary sensorimotor cortex and supplementary motor area were activated in 12/14 and 11/14 such tasks, respectively. During passive motion tasks, on the other hand, weak activation occurred at the contralateral side of the primary sensorimotor cortex in all cases, but in the contralateral supplementary motor cortex in only three. In the ipsilateral primary sensorimotor cortex and supplementary motor area, there was no activation. Conclusion: Compared with the active motion task, activation occurring in the contralateral primary sensorimotor cortex and supplementary cortex was weaker and less frequent during the passive task, and during this latter, the ipsilateral motor cortex remained inactive. These results may be useful for the clinical application of functional MR imaging in unconscious patients or in animal studies.

覺에로의 接近에 關한 一小考

임명관 東國大學校 釋林會 1982 석림 Vol.16 No.-