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최준식,유재신,박용채,인진환 한국약제학회 1996 Journal of Pharmaceutical Investigation Vol.26 No.2
This study was attempted to investigate the pharmacokinetic interaction between sodium valproate (4, 8, 16 ㎎/㎏, i.v.) and phenytoin (4 ㎎/㎏, i.v.) in rabbits. The plasma concentration and area under the curve (AUC) of phenytoin were increased significantly (p<0.05, p<0.01) when coadministered with sodium valproate (4, 8, 16 ㎎/㎏g) in rabbits. The volume of distribution and total body clearance of phenytoin were decreased significantly (p<0.05, p<0.01) when coadministered with sodium valproate (8, 16 ㎎/㎏) in rabbit. From the results of this experiment, it is desirable that dosage regimen of phenytoin should be adjusted and therapeutic drug monitoring should be performed for reduction of side or toxic effect when phenytoin will be coadministered with sodium valproate in clinical use.
이용빈(Lee, Yongbin),이주영(Lee, Juyoung),인진환(In, Jinhwan),이지은(Lee, Jeeun),조용훈(Cho, Yonghoon) 한국주거학회 2020 한국주거학회 학술대회논문집 Vol.32 No.2
The purpose of the research is to discover the social problems of the elderly as they enter into an 1)aging society and utilize them to plan the overall plan of the city, compare the 2)lifestyle and patterns of the users and analyze the physical activity ability of the elderly. Specifically, the proposal to connect a single 4)garden path in the form of a 3)platform-type cohabitation is intended to try to resolve the isolation, depression, and social isolation of the elderly through a community between various users in the 3)platform and the 4)garden.