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이혜원,최무영,차배천,Lee, Hye-Won,Choi, Moo-Young,Cha, Bae-Cheon 한국생약학회 1998 생약학회지 Vol.29 No.1
It has been known that diseases related with aging or cancer result, at least in part, from free radicals, and antioxidants may reduce or prevent the abnormalities associated with free radical formation via its scavenging action. Thus, this study was carried out to investigate the antioxidative and antimicrobial activities of nut species for the purpose of developing antioxidant from natural products. Antioxidant activities of four kinds of nuts such as chestnut, groundnut, walnut and acorn were examined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. The extracts from chestnut hull and acorn barnyard millet showed strong antioxidative activities among 10 samples tested. Because of their highest antioxidative activity among 10 samples, radical scavenging effects of 4 different extract compartments (Hexane, EtOAc, BuOH and $H_2O$ extracts) from chestnut hull and acorn barnyard millet, were further examined by DPPH method. EtOAc and BuOH extracts exhibited antioxidative activities similar to those of natural, tocopherol or synthetic antioxidants, BHA. These findings demonstrates that major fraction of the antioxidative activity of chestnut hull or acorn barnyard millet was the EtOAc and BuOH extract compartments. However, antimicrobial activities against food-related bacteria and yeasts was relatively weak.
학교도서관과 MLA 연계를 위한 교육 온톨로지 모형 구축에 관한 연구
이혜원,Lee, Hye-Won 한국비블리아학회 2008 한국비블리아학회지 Vol.19 No.1
The advantage of ontology leads a new knowledge system through integrating existing knowledge system and descriptive element of the concept. This study based on the advantage of ontology, providing a modeling education ontology that considered educational circumstances and related objects-person, organization, educational resources and so forth. Therefore, this study developed the framework for education ontology that provided link between school library and MLA to practice teaching-learning activity, these characteristics of educational ontology were as follows : the first, utilizing the existing education metadata and ontology, the second, representing a concept of educational ontology, subsequently defining classes and properties of education domain, the third, adding new classes and properties to connect existing classes and properties.
이혜원,황성원,고병섭,김호경,Lee, Hye-Won,Hwang, Seong-Won,Ko, Byoung-Seob,Kim, Ho-Kyoung 한국생약학회 2001 생약학회지 Vol.32 No.1
Epimedii Herba has been used for tonic, cardiotonic, impotency, amnestic and diuretic. Icariin, a main component was isolated from the Epimedii Herba and identified by the spectroscopic methods. In order to evaluate the quality of Epimedii Herba purchased from various regions of Korea, quantitative determination of icariin in Epimedii Herba using HPLC method has been conducted. Quantitative analysis showed the average amount of icariin in commercial 42 samples was 0.34% on the dry weight basis.
가토 간내 선택적 담관결찰후 간부피의 변화에 대한 실험적 연구
이혜원,윤엽,고영태,최우석,임주원,오주형,임형택,김윤화,이석환,Lee, Hye Won,Yoon, Yup,Ko, Young Tae,Choi, Woo Suk,Lim, Joo Won,Oh, Joo Hyeong,Rim, Heyong Teck,Kim, Youn Wha,Lee, Seok Hwan 대한영상의학회 1998 대한영상의학회지 Vol.39 No.6
Purpose : To evaluate the role of bile duct obstuction in the development of atrophy of the liver, using ananimal model. Materials and Methods : Seven rabbits were divided into two groups : group 1(n=5), in which therewas selective bile duct ligation, and group 2(n=2), which underwent a sham operation. Each group was evaluatedusing CT for changes in hepatic volume after selective bile duct ligation or a sham operation. In group I, thediameter of dilated bile duct was measured 2, 4, 8, 12 and 16 weeks after bile duct ligation, while gross andhistologic change were evaluated in all cases. Results : In group 1, bile duct dilatation was seen on CT two weeksafter selective bile duct ligation, and did not change significantly during follow-up. In four of five cases, CTrevealed no evidence of significant atrophy of the involved segment. Pathologic specimens, however, revealeddilatation of the bile duct, periductal fibrosis, infiltration of chronic inflammatory cells, and periportalfibrosis. One of five cases showed segmental liver atrophy after selective bile duct ligation. In addion to theabove pathologic findings, there was obstruction of the portal vein by foreign body reaction. In group 2, noevidence of dilated bile duct or liver atrophy was revealed by CT or pathologic specimen after a sham operation.Conclusion : During long-term follow-up of 16 weeks, obstruction of the bile duct did not play a major role in thedevelopment of lobar atrophy in the rabbit.
말기암 환자 가족에 대한 호스피스 팀의 정보적 지지 제공 효과
이혜원,Lee, Hye-Won 한국호스피스협회 2001 호스피스 학술지 Vol.1 No.1
To evaluate the effect of informational support by hospice team on family caregivers of terminally ill cancer patients, 22 family caregivers of D University Hospital in Daegu city were participated. The research was conducted from Aug. 16th to Oct. 28th 2000 by using self-reported questionnaires. The instruments used in this study were the Weinert's scale of perceived social support, Spielberger's state anxiety inventory, CES-D, and Ellison and Paloutzian's spiritual well-being scale. The intervention was designed to give educational and counselling program up to 7 times within 4 weeks. Educational and counselling booklets which made by the researcher were used step by step by hospice team. The data were analysed frequency, percentage, Wilcoxon Singed Ranks Test Test with SPSS Win 10.0/PC. The results obtained from this study were as follows: 1.The perceived social support of family caregivers was significantly increased after ready planned informational support was applied by hospice team(z=-3.045, p=0.002). 2.The anxiety of family caregivers was significantly reduced after ready planned informational support was applied by hospice team(z=-3.348, p=0.001). 3.The depression of family caregivers was significantly reduced after ready planned informational support was applied by hospice team(z=-3.641, p=0.000). 4.The spiritual well-being score of family caregivers was not significantly improved after ready planned informational support was applied by hospice team(z=-0.422, p=0.673). In conclusion, the results of this study clearly suggests that the informational support provided by hospice team not only increased the family caregivers' who are caring for terminally ill cancer patients. Therefor the informational support program designed by researcher for family caregivers who are caring for terminally ill cancer patients should be utilized and expended.
역사용어 온톨로지 모형 적용 방안 연구 - 한국근현대사 인물을 중심으로 -
이혜원,윤소영,Lee, Hye-Won,Yoon, So-Young 한국비블리아학회 2011 한국비블리아학회지 Vol.22 No.1
본 연구에서는 역사인물 중심의 온톨로지를 구축하기 위해 기존의 한국역사용어시소러스의 문제점을 분석하는 동시에 한국역사용어시소러스 및 국편의 다양한 정보검색 시스템을 활용하는 전문가들의 인터뷰를 실시하였다. 한국역사용어시소러스의 개념 표현 기준과 전문가들이 작성한 마인드맵을 분석하여 현재 시스템과 전문가간의 정보 표현의 차이를 확인하였다. 이를 바탕으로 역사정보 이용자들의 정보요구에 부합하고 잠재력 있는 정보검색시스템에 적용할 역사용어 온톨로지 모형을 설계하였다. 본 연구에서는 먼저 클래스, 속성을 정의하고, 인스턴스 입력시 고려해야 할 점들을 나열함으로써, 역사정보가 갖는 고유한 특성들을 정리하였다. 또한 온톨로지의 장점인 개념 확장을 활용하여 역사정보의 다양한 특성들을 조합하고 이를 통해 새로운 정보를 제공할 수 있는 가능성을 제시하였다. The purpose of the study is to construct a History Ontology Model for historical person to analyse issues of Korean History Thesaurus and interview history specialists who are use information systems in National Institute of Korean History. This study verifies the difference between both descriptions through comparative analysis of term concept in Korean History Thesaurus and mind-map written by history major. Based on this, we build history ontology model to meet users' information needs and adapt to information retrieval system. First, to organize unique features of history, we define class and attribute and then enlisted considerations for instance input. The study suggests a possibility of new service through combination multiple features using concept extension that is a strength of ontology.
이혜원,Lee, Hye-Won 한국비블리아학회 2012 한국비블리아학회지 Vol.23 No.1
FRSAD과 온톨로지 모형간의 연계는 어떠한 정보구현시스템이나 특정 상황에서도 독립적인 상위 계층의 지식구조를 제안하고, 의미 연결, 지식구조, 주제접근, 상호운용성 등을 확보하기 위한 노력이다. FRSAD 모형을 현실적인 정보환경에 적용하고, 도서관 안팎 어디서나 자유롭게 정보를 확인하고 공유하기 위해서는 지식표현 인코딩 체계가 필요하다. 본 연구에서는 웹 온톨로지 언어인 OWL를 사용하여 FRSAD 모형을 온톨로지 구조로 표현하였으며, 이를 확인하기 위해 Prot$\acute{e}$g$\acute{e}$를 사용하여 FRSAD 온톨로지 모형을 시범적으로 구축하였다. Mapping FRSAD and other ontology models intends to suggest a higher knowledge level that is independent of any information implementation system or specific context, and to endeavor to focus on the semantics, knowledge structures, subject access, and interoperability. Providing an application of FRSAD model to information environment and representing and sharing the information within the library sector and beyond, there needs encoding scheme for knowledge representation. This study suggested an OWL based ontology architecture for FRSAD model and demonstrated the pilot FRSAD ontology model using Prot$\acute{e}$g$\acute{e}$ software.
이혜원,이용민,Lee, Hye-Won,Lee, Yong-Min 한국전기화학회 2012 한국전기화학회지 Vol.15 No.3
리튬이차전지의 수요가 소형 휴대용 전자기기에서 중대형 전기자동차와 에너지저장장치로 변화함에 따라, 요구되는 전지 특성도 크게 달라지고 있다. 10년 이상의 장기 신뢰성, 팩 수준의 안전성, 가격 경쟁력 확보 등 기존 소형 전지보다 크게 강화된 요구 조건뿐만 아니라, 고출력 특성도 함께 필요로 한다. 그런데, 출력을 측정하기 위해서는 전압과 전류가 동시에 측정 및 제어되어야 하기 때문에, 기존의 단위셀 용량 측정보다 훨씬 어렵다. 또한, 측정 방법의 선택뿐만 아니라 출력유지시간, 충전상태(State-of-Charge, SOC), Cut-off 조건, 측정온도 등의 측정 조건에 따라서도 그 측정값이 크게 달라지는 경향이 있다. 본 논문에서는 HPPC (Hybrid Pulse Power Characterization)법, J-pulse(Japan Electric Vehicle Association Standards, JEVS D 713)법, 정출력 측정법(Constant Power Measurement)의 측정 원리 및 실제 실험에 어떻게 적용해야 하는지 설명하고, HEV(Hybrid Electric Vehicle)용 단위셀을 이용해 출력법간 측정 결과를 비교 분석한다. As the market of lithium secondary batteries moves from mobile IT devices to large-format electric vehicles or energy storage systems, the strengthened battery specifications such as long-term reliability longer than 10 years, pack-level safety and tough competitive price have been required. Moreover, even though high power properties should also be achieved for hybrid electric vehicles, it is not easy to measure accurate power values at various conditions. Because it is difficult to choose a proper measurement method and its experimental condition is more complex comparing to capacity measurement. In addition, the power values are very sensitive to power duration time, state-of-charge (SOC) of cells, cut-off voltages, and temperatures, whereas capacity values are not. In this paper, we introduce three kinds of power measurement methods, hybrid pulse power characterization (HPPC) suggested by US FreedomCar, so-called J-pulse by Japan electric vehicle association standards (JEVS) and constant power measurement, respectively. Moreover, with pouch-type unit cells for HEV, experimental power data are discussed in order to compare each power measurement.
TPCK 프레임워크를 기반으로 한 교과교사와 사서교사 간의 교수-학습 협력에 관한 연구
이혜원,Lee, Hye-Won 한국도서관정보학회 2008 한국도서관정보학회지 Vol.39 No.2
본 연구에서는 정보활용능력을 향상시키기 위해 학교도서관의 사서교사와 일반 교과의 교사들 간의 협력 방안을 제시하고자 하였다. 또한 교육의 또 다른 주체인 학생을 중심으로 한 부분을 확대함으로써 좀 더 효율적인 교수-학습이 이루어질 수 있도록 하였다. 무엇보다 교사와 학생들의 커뮤니케이션에서 직접적인 교환이 이루어지는 지식을 중심으로 주제, 교육학적인 배경, 정보기술의 활용 등을 고려한 모형을 제안하였다. In this study, collaboration of teacher librarians and subject teachers in school libraries has been investigated(tried, attempted, suggested) in order to improve the information literacy. The effective teaching-learning can be conducted by extending student's roles, which are essential elements in school education. Above all, the model. focused on direct exchange of knowledges in communications between teachers and students has been suggested with consideration of content knowledge, pedagogical knowledge, and technological knowledge.
이혜원,박진우,서조영,이재목,Lee, Hye-Won,Park, Jin-Woo,Suh, Jo-Young,Lee, Jae-Mok 대한치주과학회 2009 Journal of Periodontal & Implant Science Vol.39 No.2
Purpose: The purpose of this study was to evaluate the compliance to maintenance schedules recommended supportive periodontal therapy(SPT) and to determine differences in the characteristics of compliant and non-compliant patients. Methods: 414 patients commencing SPT after active periodontal treatment from 2003 to 2005 were included in this study. Based on their compliance with the suggested maintenance schedule, patients were classified as compliant and non-compliant groups. Also patients classified by gender, age, degree of alveolar bone loss and treatment rendered. The association between compliance and patient characteristics was assessed by odds ratio in logistic regression analyses. Results: Only 47% of the initial patient was found to be compliant at the end of August 2008 and 20.8% patients were lost in the first year of SPT. There were significant differences between compliant and non-compliant regard to age, degree of alveolar bone loss and treatment rendered. Conclusions: In conclusion, compliance with SPT generally poor and patients who were older, treated surgical therapy and with mild alveolar bone loss are more compliant to SPT.