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- 저자 : 이현태(Hyun-Tae Lee) (검색결과 17 건)
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이현태,장호선,권경술,정태안,오창근 ( Hyun Tae Lee,Ho Sun Jang,Kyung Sool Kwon,Tae Ahn Chung,Chang Keun Oh ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.4
Sebaceous carcinoma is a rare, aggressive, malignant tumor derived from the adnexal epithelium of sebaceous glands. This tumor occurs most frequently on the eyelids, but may occur on the extraoccular sites. Clinically, it is presented as a solitary tumor in most cases and very rarely as multiple ones. We report a case of multiple. sebaceous carcinomas on the frontal region in a 73 year-old man. He had well-demarcated, reddish, asymptomatical, protruding masses on the frontal region for 2 months. The histopathologic findings showed irregular, variable sized, lobular tumor nests of the entire dermis, and each lobule was composed of foamy cytoplasmic atypical cells and undifferentiated cells containing, eosinophilic cytoplasm. He was treated with surgical excision and no recurrence was observed during 6 months. (Kor J Dermatol 1997;35(4): 824 - 829)
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이현태,권경술,장호선,정태안,오창근 ( Hyun Tae Lee,Kyung Sool Kwon,Ho Sun Jang,Tae Ahn Chung,Chang Keun Oh ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.5
Background: Xanthomas consist of localized infiltrates af lipid-containing histiocytic foam cells that are usually found within the dermis or tendons. They frequently arise in the presence of a disturbance of lipid metaholism. Objective : The purpose of this study was to elucidate the clinical and histopathological characteristics of xanthomas. Methods : Eighteen cases of xanthoma confirmed clinically and histopathologically were ana lyzed. Xanthelasma was excluded in this study. Results : The results were summarized as follows. 1. The incidence of xanthoma was 0.03% of the total number of dermatologic patients. 2. The ratio between male and female was 1:2.6 and the age distribution varied from 2 to 65 years old(mean age : 37.4 years-old), and the distribution of age of onset was from birth to 62 years old(mean age of onset: 32.9 years old). 3. The frequencies of elinical types, in descending order, were xanthoma tuberosum(XT) 44.4%, xanthoma planum(XP) 27.8%, Xanthoma eruptivum(XE) 22.2%, and xanthoma striatum palmare (XSF) 5.6 % . 4. The common sites were the knee, elbow and buttock in XT; The upper and lower extremities in XE, the cheek, neck and chest in XP; palmar creases in XSP. 5. Serum lipid abnormalities were detected in 88.9%(16/18). 6. The associated diseases were hypothyroidism, diabetes, hepatomegaly, psoriasis. 7. A family history was significant in 2 patients with XT. 8. The associated hyperlipoproteinemia was type IIa(4/8), IIb(2/8), III(1/8), IV(1/8) in XT, type IIa(2/5), IV(2/5) and normolipoproteinemia(1/5) in XP, type I(1/4), IV(1/4), V(1/4) and normolipoproteinmia(1/4) in XE, type III(1/1) in XSP, respectively. 9. Diet, alone or combination with antilipidemic drugs were used for treatment, and the lesions were cleared in 2(one XP and one XE) of 7 patients that could be followed up. 10. Histopathological features revealed that lipid-laden foamy histiocytes were observed in all cases of xanthomas and foreign body giant cells were more common than Touton giant cells. Conclusion : Xanthomas were not so common disorders compared with the incidence of hyperlipoproteinemia and were more common in females than males. The most common clinical type was XT except for xanthelasma. The most common associated hyperlipoproteinemia in each type of xanthoma was type II in XT, type IIa and IV in XP, variable types in XE, type III in XSP, respectively. Lipid-laden foamy histiocytes were observed in all cases of xanthomas and for eign body giant cells were more common than Touton giant cells. (Korean J Dermatol 1997;35(5): 940-946)
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카포시 육종과 동반된 Idiopathic CD4 + T Lymphocytopenia
이현태,장호선,권경술,정태안 ( Hyun Tae Lee,Ho Sun Jang,Kyung Sool Kwon,Tae Ahn Chung ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1
Idiopathic CD4+ T lymphocytopenia(ICL) is a new disease entity characterized by depletion of helper T cells apparently without any evidence of HIV infection. We report a case of ICL associated with Kaposis sarcoma(KS) and pneumocystis carinii pneumonia(PCP) in a 34-year old woman. She developed violaceous, protruding masses on scalp, back, both extremities, palms, soles, left. first toe and peritonsillar region for 2 months. These lesions were confirmed as KS by histopathologic findings. Chest X-ray and HRCT findings represented PCP and KS. Absolute deficiency of CD4+ T cell was detected in the count of T cell subsets. Serologic tests for HIV-1, 2 and HTLV I, -II were negative. And she was absent any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells. By CDC criteria, a diagnosis of ICL was made. Because of aggravation of PCP and lung involuement of KS, she died at 22nd day after admission. (Kor J Dermatol 1997;35(1): 191-195)
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이현태 ( Hyun-tae Lee ),최중국 ( Joong-kook Choi ) 한국정책연구원 2021 한국정책논집 Vol.21 No.1
일차성 불면장애는 일반인구의 20-40%가 겪어본적이 있으며 10-20%는 계속 겪고 있는 질병이다. 삶의 질과 일상생활에 어려움을 주는 것을 넘어 신체적, 정신적 질환으로 이환될 가능성이 높다. 그럼에도 불구하고 일반적인 치료 가이드라인은 수면위생 개선, 약물요법, 인지행동치료를 제시하고 있다. 수면위생은 효과가 제한적이고 약물요법은 약물부작용이 있으며 인지행동치료는 전문가가 필요하기 때문에 대체치료의 중요성이 대두되고 있다. 이 연구는 기존의 치료를 확장시킬수 있는 안전하고 효용성이 증명된 대체치료를 소개한다. 2021년 10월까지 PubMed에서 수기 검색한 논문들을 고찰하는 형식이며 근거 수준이 높은 논문들을 대상으로 하였다. III.1에서는 지역사회의 간호사를 교육시켜 시행한 인지행동치료가 효과를 거둔 것을 제시하고 있으며 III.2에서는 유산소 운동, III.3에서는 동양의학, III.4에서는 생체리듬 치료를 소개하며 그 안정성과 효용성에 관해 고찰했다. III.5에서 약초 요법은 효과가 증명되지 않았고 부작용이 있음을 제시했다. 일차성 불면장애에 적용가능한 안전하고 효과적인 대체치료로는 지역사회 간호사를 통한 인지행동치료 그룹, 유산소 운동, 침치료, 이혈요법, 빛 치료, 멜라토닌 치료 등이 있으며 일반인구집단에서 일차치료에 활용할 경우 질병 극복에 도움이 될 것이다. 약초 요법은 아직 근거 수준이 미비하다. Primary insomnia is a disease that 20-40% of the general population have experienced and 10-20% continue to suffer from. Nevertheless, general treatment guidelines suggest improvement of sleep hygiene, drug therapy, and cognitive behavioral therapy. This study, based on the previous publications, attempts to introduce a safe and effective alternative treatment that may expand existing treatments. Along this line, we focused on (1) Cognitive behavioral therapy, (2) Aerobic exercise, (3) Oriental medicine, and (4) Biorhythm therapy from a perspective of their stability and efficacy. Our study suggests that the cognitive behavioral therapy groups through community nurses, aerobic exercise, acupuncture, blood pressure therapy, light therapy, and melatonin therapy appear to meet the stability and efficacy issues with varying degrees, but the level of evidence for herbal remedies is still insufficient and awaits a further study.
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이현태(Lee, Hyun-tae) 한국고대사학회 2013 韓國古代史硏究 Vol.0 No.70
경희대학교 박물관은 1969년 경주 인왕동 19?20호분을 발굴조사한 바 있고, 이에 대한 보고서를 1974년 간행하였다. 그런데 당시 보고서에는 출토유물 중 일부만 수록 되었을 뿐만 아니라 내용상 오류가 있는 부분도 있다. 이에 보고서의 잘못된 부분을 바로 잡고 학계에 보고되지 않은 유물 가운데 자료적 가치가 높은 유물을 소개함으로써, 인왕동 19?20호분의 발굴성과가 학술적으로 활용될 수 있는 토대를 마련하고자 이 글을 작성하게 되었다. 이를 위해 우선 발굴 당시의 사진이나 도면 등을 바탕으로 被葬者의 頭向이나 墓槨의 구조 등을 재검토하여 보고서의 기술상 문제가 있는 부분을 보정하였다. 다음으로 금속유물을 중심으로 미보고된 유물을 소개하였는데, 특히 20호분에서 출토된 안장 장식과 관련이 있으리라고 여겨지는 馬具類와 19호분 F곽 출토 철정 등은 출토사례가 드문 자료이다. 이 외에도 19호분 G곽에서 출토된 환두대도 등도 학술적으로 활용 가치가 높은 자료로 판단된다. 마지막 장에서는 새롭게 보고한 자료의 의의와 발굴성과 등에 대해 짚어보았다. 새로이 보고한 자료 가운데는 5세기 후반이나 6세기 전반으로 편년되는 것도 있어서 인왕동 19?20호분에서 출토된 耳飾이 古式이란 점에 착안하여 고분의 축조시기를 5세기 전반으로 파악한 견해는 재검토가 필요하게 되었다. 뿐만 아니라 19호분 D곽 피장자의 頭向이 西向이라는 사실은 적석목곽묘 피장자의 두향을 파악하기 어려운 경우 피장자의 두향을 기본적으로 東向으로 간주해 온 지금까지의 인식을 전환시킬 필요가 있음을 알려주었다. 이렇듯 인왕동 19?20호분에서 확인된 유구의 새로운 양상과 여기서 출토된 미보고유물은 학계에 처음 공개된 新資料인 동시에 기왕의 연구 경향에 再考를 요하는 부분도 있어서, 고분 연구를 비롯한 신라 고고학 연구에 중요한 자료로 이용될 수 있을 것으로 생각된다. Kyung Hee University Museum conducted an excavation research on Gyeongju Inwang-dong Tomb No. 19 and No. 20 in 1969 and issued a report on the excavation research in 1974. Unfortunately, the report did not deal with all the excavated artifacts and included a few errors in content. Thus, this study was conducted to lay the foundation for academic utilization of excavation results of Tomb No. 19 and No. 20 by correcting errors in the report and introducing new artifacts of great value as scholarly research materials among artifacts not reported to the academic community. For this purpose, this study reexamined the direction of the buried person"s head and the structure of chamber based on photographs and drawings made when the tombs were excavated and corrected technical errors in the 1974 report. This study also introduced unreported artifacts focusing on metal artifacts. Especially, horse trappings considered to be associated with the saddle excavated from Tomb No. 20 and iron nails excavated from Coffin F in Tomb No. 19 are rare academic materials. In addition, sword with ring pommel and other goods excavated from Coffin G in Tomb No. 19 are also considered to have great academic value. In the last chapter, this study dealt with the meaning of newly reported artifacts and newly discovered excavation results. Given that some of newly reported artifacts are believed to date from the late 5th century or the early 6th century and that earings excavated from Tomb No. 19 and No. 20 are old style, there is a need for reviewing the existing opinion that these tombs were built in the early 5th century. Besides, the fact that the head of the person buried in Coffin F of Tomb No. 19 looked west requires a perceptual shift of scholars who regarded the head direction of a person buried in a wooden chamber tomb with stone mound as east when it was difficult to find the direction of buried person"s head. In conclusion, the author believes that new facts relating to Gyeongju Inwangdong Tomb No. 19 and No. 20 and newly reported artifacts requiring reconsideration of conventional research tendency can be used as important materials for archaeological research on Silla including ancient tomb research.
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이현태(Lee, Hyun-tae) 한국역사연구회 2011 역사와 현실 Vol.- No.81
So far, two roof tile pieces, with the line saying 'The Seal of Namgung' imprinted upon it, have been found both from the National Gyeongju Museum site and from the ruins at the address of 696-2, Dongcheon-dong, Gyeongju. There have been many suggestions concerning the true nature of this 'Namgung.' Some people thought of it as a part of a palatial structure, while others considered it to be a governmental office for handcraft manufacturing industry. However, close analysis of the relics and the vestiges shows us that both sites had something to do with ancestral rituals and ceremonies. In addition, both pieces of roof tiles seem to have been made between the mid-9th century and the 10th, considering the level of technical manufacturing featured by them. It is also determined that the term 'Namgung' was once used as another name of the Ye-bu office[Ministry of Protocols], based upon the contents written upon the stele of Monk Nang'hye of the Seongju-sa temple, which was built at the same period as these tiles. So, it seems that 'Namgung' was a term that referred to the Shilla dynasty's Ministry of Protocols. And because the term only appeared in a specific time period(from the mid-9th century through the early 10th), it is surmised that the term finally emerged when ancient official titles were being replaced in the middle of the 9th century.
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융합성 망상 유두종증의 병인에 있어 세균과의 관련성에 관한 연구
이현태 ( Hyun Tae Lee ),정태안 ( Tae Ahn Chung ),권경술 ( Kyung Sool Kwon ),장호선 ( Ho Sun Jang ),오창근 ( Chang Keun Oh ) 대한피부과학회 1998 大韓皮膚科學會誌 Vol.36 No.1
Background: The pathogenesis of confluent and reticulated papillomatosis(CRP) is still unknown, although many theories have been suggested. It is stressed that abnormal host response to colonization of pityrosporum orbiculare might play a role in the pathogenesis of CRP, but is not completely understood. Frequently, we have observed bacterial colonies in the stratum corneum and, especially, within the hair follicles from biopsy specimens of patients with CRP. In addition, successful treatment for CRP with minocycline, a derivative of tetracyclines, has been reported continuously. Objective : The purpose of this study was to document the possible association of bacterial factors in the pathogenesis of CRP and to elucidate the effectiveness of minocycline. Methods : We performed Brown and Brenn gram staining in 12 biopsy specimens, bacterial cultures, identification of microorganisms and antibiotics sensitivity testing including minocycline. We administered oral minocycline with an initial dose of 100mg per day for 1 to 3 months and a maintenance dose 50mg per day for I to 2 months, then evaluated the response of treatment. Results : 1. On Brown and Brenn staining, the gram positive bacterial colonies that stained dark bluish or nearly black were observed within the infundibulum of hair follicles in 10 out of 12 biopsy specimens(83.3%) and on the keratotic invagination of stratum corneum in 11 out of 12 biopsy specimens(91.7%). 2. Histological features of regions where bacterial colonies were observed showed, hyperkeratosis and keratotic invagination on the stratum corneum in all cases. Hyperkeratosis(66.7%), parakeratosis(16.7%), inflammatory cell infiltration(25.0%), perifollicular fibrosis(33.3%), and abnormal keratin in sebaceous ducts(50.0%) were shown in hair follicles. 3. In anaerobic cultures, no bacteria was grown. In aerobic cultures, staphylococcus species were identified in 6 cases, streptococcus viridans in one case, sternotrophomonas maltophilia in one case. In the susceptibiliity test, minocycline was sensitive in 7 from 8 cases. 4. The therapeutic response to minocycline was observed within one month in all cases, and the time to clear the lesions was 1/2 month in 2 cases, 1 month in 4 cases, 2 months in 5 cases, 3 months in one case, respectively. Conclusion : Form these results, we suggest that bacterial factors may play an important role in the pathogenesis of CRP and that the action mechanism of minocycline in the treatment of CRP may be due to antibacterial effects. (Korean 1 Dermatol 1998;36(1): 78-85)
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