경계성 난소 종양의 보존적 수술 후 불임 환자에서 체외수정시술의 유용성

이현주,안가영,한호섭,박찬우,양광문,이인호,김태진,임경택,이기헌,강인수,Lee, Hyun-Joo,Ahn, Ka-Yougng,Hahn, Ho-Suap,Park, Chan-Woo,Yang, Kwang-Moon,Lee, In-Ho,Kim, Tae-Jin,Lim, Kyung-Taek,Lee, Ki-Heon,Kang, Inn-Soo 대한생식의학회 2007 Clinical and Experimental Reproductive Medicine Vol.34 No.2

목 적: 경계성 난소 종양 환자에 있어서 보존적 수술 후 임신에 성공한 군과 비임신 군간 환자의 특성에 차이가 있는지 알아 보았으며, 경계성 난소 종양의 보존적 수술 후 체외수정시술의 유용성에 대해 알아 보았다. 연구방법: 1995년 1월부터 1999년 10월까지 경계성 난소 종양으로 보존적 술을 시행 받은 가임 여성 가운데 임신에 성공한 군 (14명)과 비임신 군 (30명)간 환자의 특성에 차이가 있는지 알아 보았으며, 비임신 군 가운데 불임을 주소로 내원하여 체외수정시술을 시행 받은 5명의 10주기를 대상으로 체외수정시술 결과 및 체외수정시술 후 난소 종양의 재발 유무를 추적 관찰하였다. 결 과: 경계성 난소 종양의 보존적 수술 후 임신에 성공한 군과 비임신 군간 환자의 평균 나이는 25.9세와 27.0세이었으며 혈청 CA-125 수치는 59.7 U/m와 72.0 IU/ml로 비임신 군에서 높은 경향을 보였으나 통계적 유의성은 없었다. 불임을 주소로 체외수정시술을 시행 받은 5명의 10주기 (attempt IVF cycle) 가운데 취소된 2주기를 제외하고 (attempt cycle cancellation rate, 20.0%) 채취된 난자 수는 평균 5.6개 (2$\sim$16개)이었으며 수정율은 14.5% (50.0$\sim$100.0%)이었다. 평균 2.4개 (1$\sim$4개)의 배아를 이식하였으며 배아이식 주기당 임신율과 착상율 및 출생율은 각각 50.0% (4/8 cycle), 31.6% 및 50.0% (4/8 cycle)이었다. 체외수정시술 후 평균 29.6개윌 (14$\sim$61개월)의 추적 관찰 기간 동안 난소 종양이 재발된 경우는 없었다. 결 론: 경계성 난소 종양의 보존적 수술 후 임신에 성공한 군과 비임신 군간 환자의 특성에 차이가 없으며, 보존적 수술 후 체외수정시술의 결과는 비교적 만족할 만한 수준으로 체외수정시술은 경계성 난소 종양의 보존적 수술후 고려될 수 있으나 향후 많은 환자를 대상으로 한 장기간의 추적 관찰을 필요로 한다. Objective: To examine determinants of successful pregnancy and evaluate COH-IVF outcomes of infertile patients after conservative surgical treatment of borderline ovarian tumor (BOT). Methods: In women of BOT (n=93), from January 1995 to December 1999, 44 of 93 women underwent conservative surgical treatment. From theses 44 women, patients characteristics, surgical and histological parameters were compared between 14 women who conceived and 30 women who failed to conceive. For 5 infertile women of 30 women who failed to conceive, 10 attempt IVF cycles were analysed; clinical pregnancy rate (CPR), implantation rate (IR) and live birth rate (LBR). Results: Women who conceived tend to be younger (25.9 vs 27.0 years) and lower serum CA-125 level (59.7 vs 72.9) compared to women who failed to conceive without significant difference. For 8 cycles out of 10 attempt IVF cycles, except for 2 cancellation cycles, the mean number of oocytes retrieved was 5.6 (range 2$\sim$16) with a mean fertilization rate of 74.4%. The CPR, IR and LBR per embryo transfer were 50.0% (4/8 cycles), 31.6% (6/19) and 50.0% (4/8 cycles) respectively. During the mean follow-up period after COH-IVF initiation, 29.6 (range 14$\sim$61) months, no recurrence was found. Conclusion: No determinant of successful pregnancy was found after conservative treatment for BOT. COH-IVF may be considered for infertile patients after conservative treatment of BOT. However, larger clinical studies with longer follow-up are necessary to evaluate the safety and efficacy of COH-IVF. All patients should be informed of the potential risks associated with ovarian hyperstimulation and close follow-up is necessary after COH-IVF.

해방 후 李承燁의 ‘統一民族國家’ 건설운동(1945~1953)

이현주(Lee, Hyun-Joo) 인천대학교 인천학연구원 2007 인천학연구 Vol.6 No.-

It was through the process of a merger of three parties that Lee Seung-Yeop rose as a leader of the socialist state movement in South Korea. The inauguration ceremony of the South Korean Worker's Party (남조선노동당) was held under his leadership in November, 1946 after Park Hun-young went to North Korea. He visited secretly PeyongYang accompanied by Kim Sam-yong and achieved the principal that the Opposing Parties individually had to join the South Korean Worker's Party established by centralizing the Korean Communist party. After crossing over the border into North Korea, Lee Seung-Yeop was appointed as a head of judicature of the First Cabinet, North Korea. However, his role was prominent in the Parties. Lee Seung-Yeop rose to the position supervising operations against the South as second secretary of the Party as well as was elected an member of Nine Politics Committeemen of the Korean Workers' Party(조선노동당) which was born due to the merger of Parties. Since then, his activities were concentrated on the leadership for guerrilla war by a partisan. He reorganized a guerrilla unit into three groups in order to develop systematically the guerrilla that was being sporadically progressed in South Korea in July, 1947 and the first group was dispatched to the South in his order. The Korean War was a watershed deciding his fate. He who sent to the South as plenipotentiary of liberated area as soon as the war occurred suddenly was nominated a representative of Seoul city of the Armed Services Committee, North Korea and Seoul temporary Council of People's Commissars the minute that Seoul was occupied. He, an chairman of Council People's Commissars, had to support the People's Army advancing South, recovering ruined product facilities, roads, bridges etc. The management for relief programs, citizens' mobilization, letting volunteer armies go to the war, cultural propaganda programs, land reform, health movement, product power increase was encouraged for about two months. Orders for a guerilla continued. At the same time, Lee Seung-Yeop made people sympathize with the People's Army by infiltrating espionage operators each province, landing the mustered guerrilla to the South through the East Sea on June 25, 1950. Even though his power decreased in the situation an armistice was argued, the first half of 1951, his leadership to the guerrilla was well. The end of the war with Incompletion brought a tragedy to him. Lee Seung-Yeop was arrested with other 11 fellows of the South Korean Worker's Party faction on August 3, 1952. He disappeared in the North, 'a forever strange land', after being sentenced to death and property confiscation upon a quick trial for 4 days, on August from 3 to 6, 1953. The event was not ended in Lee's death. The Purge against the South Korean Worker's Party continued until 1955 and became an overture of the purge against Soviet Union Group(소련파) and Yeon Ahn Group(연안파). His tragic death was not resulted from 'conspiracy of armament riots for the plot against government', but the fact he couldn't clean himself of suspicion even in North Korea, not Kim Il-Sung but Pak Hung-Young whom he assisted as the chief until he died, even if shouting many times 'General Kim Il Sung cheers!' at the official meeting. He failed to free himself from 'a second man of the South Korean Worker's Party until the last moment.

추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 1종의 Sterol과 3종의 배당체 화합물의 단리·동정

이유건(Yu Geon Lee1),조정용(Jeong-Yong Cho),이현주(Hyun Joo Lee),이용현(Yong Hyun Lee),이상현(Sang-Hyun Lee),한태호(Tae-Ho Han),김월수(Wol-Soo Kim),박근형(Keun-Hyung Park),문제학(Jae-Hak Moon) 한국식품과학회 2013 한국식품과학회지 Vol.45 No.5

본 연구에서는 배의 유용성 증명을 위한 일환으로 배의 화학성분을 분자수준에서 밝히고자 하였다. 이에 배 과피 MeOH 추출물을 용매분획하여 얻은 EtOAc-산성 분획과 EtOAc-중성분획을 대상으로 Sephadex LH-20, silica gel, 그리고 ODS colmn chromatography와 HPLC를 이용하여 정제 및 단리하였다. 그 결과, EtOAc-산성 분획과 EtOAc-중성 분획으로부터 각각 2종씩의 화합물을 단리하였다. 단리된 화합물 1-4는 1H- 및 13C-NMR 분석을 통하여 각각 (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (화합물 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone(piceoside, 화합물 2), β-sitosterol (화합물 3), 그리고 β-sitosteryl 3-O-β-D-glucopyranoside (화합물 4)로 동정되었다. 단리된 3종의 배당체 화합물(화합물 1, 2, 4)들은 본 연구에 의해 배로부터 처음 동정되었으며, 화합물 3은 추황배로부터 처음 동정되었다. 본 연구결과가 배 함유 성분연구는 물론 배의 기능성 해명 연구에도 추후 중요한 기초자료로 활용되길 기대한다. We isolated and identified antioxidants from acidic and neutral ethyl acetate fractions of the peel of pear (Pyrus pyrifolia N. cv. Chuhwangbae). We isolated 4 compounds from the methanol extract, by using 3 different types of column chromatography (Sephadex LH-20, silica gel, and octadecylsilane) and preparative HPLC. We identified the isolated compounds as (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (compound 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone (picroside, compound 2), β-sitosterol (compound 3), and β-sitosteryl 3-O-β-D-glucopyranoside (compound 4) by nuclear magnetic resonance analysis. We are the first to report the identification of compounds 1, 2, and 4 from pear.

지신경에 발생한 신경초종 - 8예 보고 -

이현주,김지수,라인후,박일형,김풍택,Lee, Hyun-Joo,Kim, Ji-Soo,Ra, In-Hoo,Park, Il-Hyung,Kim, Poong-Taek 대한미세수술학회 2012 Archives of reconstructive microsurgery Vol.21 No.2

As a rare cause of tumor in hand, we report eight cases of neurilemmoma in the digital nerve. Enucleation of the neurilemmoma under the microscopy resulted in complete relief of the symptoms at the latest follow-up.

말초혈액 자연살해세포가 증가된 반복유산 환자의 탈락막 자연살해세포의 발현

이현주,김선행,양광문,박동욱,박찬우,홍성란,조동희,송인옥,궁미경,강인수,Lee, Hyun-Joo,Kim, Sun-Haeng,Yang, Kwang-Moon,Park, Dong-Wook,Park, Chan-Woo,Hong, Sung-Ran,Cho, Dong-Hee,Song, In-Ok,Koong, Mi-Kyoung,Kang, Inn-Soo 대한생식의학회 2009 Clinical and Experimental Reproductive Medicine Vol.36 No.3

목 적: 말초혈액 자연살해세포가 증가된 반복유산 환자군과 증가되지 않은 반복유산 환자군에서 다음 번 유산 시탈락막의 자연살해세포의 발현양상을 관찰하여 말초혈액 자연살해세포와 상관관계가 있는지 보고자 하였다. 연구방법: 말초혈액 자연살해세포가 15% 이상 증가된 반복유산 환자군 14명을 실험군으로, 15% 이하인 군 12명을 대조군으로 하여 연구를 진행하였다. 이 환자들에게서 다음 번 유산 시 착상부위를 포함한 자궁 탈락막 세포를 확인하여 면역조직화학염색을 통해 $CD56^+$와 $CD16^+$ 자연살해세포의 수를 세어 실험군과 대조군을 비교하였다. 결 과: 실험군과 대조군은 탈락막 내 $CD56^+$ 자연살해세포의 수 간에 통계적으로 유의한 차이 ($170.1{\pm}132.1$ vs. $68.3{\pm}66.1$, p=0.02)를 보였으나 둘 간의 상관관계 (r=0.229, p=0.261)는 없었다. 또한 두 군간에 $CD16^+$ 자연살해세포는 통계적으로 유의한 차이 ($25.70{\pm}11.72$ vs. $31.17{\pm}22.67$)를 보이지 않았다. 결 론: 본 연구는 말초혈액 $CD56^+$ 자연살해세포가 증가된 반복유산 환자군에서 말초혈액 자연살해세포가 증가되지 않은 군에 비하여 탈락막의 $CD56^+$ 자연살해세포가 증가되어 있음을 알 수 있었다. 이는 탈락막 자연살해세포가 반복유산의 면역학적 기전에서 중요한 역할을 할 것이라는 가능성을 제시해 주는 연구 결과이며 또한 말초혈액 자연살해세포의 측정이 반복유산 환자에서 다음 번 유산을 예측할 수 있는 유용한 지표임을 알 수 있다. Objectives: The purpose of this study was to compare the decidual NK cell populations between increased pre-conceptional peripheral NK cell population and normal pre-conceptional peripheral NK cell population in women with a history of recurrent abortion. Methods: Fourteen women with history of recurrent abortion and elevated pre-conceptional peripheral NK cell, above 15% of peripheral lymphocyte population were included in this study. As a control, twelve women with history of recurrent abortion and their peripheral NK cell percentage showed below 15% were included. Distribution of $CD56^+$ and $CD16^+$ NK cells in paraffin embedded decidual tissues including implantation sites were examined by immunohistochemical staining using anti-CD56, 16 monoclonal antibodies. After immuohistochemical staining, the numbers of decidual NK cells were counted and compared these results between study and control groups. Results: There was significant difference in decidual $CD56^+$ NK cell count ($170.1{\pm}132.1$ vs. $68.3{\pm}66.1$, p=0.02) between increased peripheral $CD56^+$ NK cell group and control group. But, there showed no statistically significant correlation between decidual $CD56^+$ NK cell count and peripheral $CD56^+$ NK cell percentage (r=0.229, p=0.261). Also there was no statistically difference decidual $CD16^+$ NK cell count between study and control group ($25.70{\pm}11.72$ vs. $31.17{\pm}22.67$), and no correlation between decidual $CD16^+$ NK cell and peripheral $CD16^+$ NK cell percentage (r=-1.40, p=0.535). Conclusions: This study shows that decidual $CD56^+$ NK cell are significantly increased in decidua of women exhibiting a history of recurrent abortion with increased $CD56^+$ peripheral NK cell. This study suggests that the percentage of peripheral NK cell reflect the expression of decidual NK cell. Consequently, pre-conceptional peripheral blood NK cell population can be the useful marker for detecting the risk of subsequent miscarriage.

보험회사의 기타포괄손익항목이 기업가치에 미치는 영향

이현주,박구용,박상섭,Lee, Hyun-Joo,Park, Gu-Yong,Park, Sang-Seob 대한경영정보학회 2017 경영과 정보연구 Vol.36 No.3

본 연구는 2021년부터 도입될 국제보험회계기준 IFRS 17의 주요내용 중 보험부채의 공정가치 평가에 초점을 두고 보험회사의 자산 및 부채에 대한 공정가치 평가항목인 미실현손익항목이 자본시장에 미치는 영향을 검증하고자 하였다. 이를 위해 상장보험회사의 분기별 재무제표에 공시되는 기타포괄손익항목의 변동액과 누계액이 주가에 미치는 영향을 Ohlson(1995) 기본모형을 확장한 검증모형을 이용하여 회귀분석을 행하였다. 실증분석결과는 다음과 같다. 첫째, 기타포괄손익변동액은 주가에 유의한 부(-)의 영향을 미치는 것으로 나타났다. 둘째, 기타포괄손익누계액은 주가에 유의한 정(+)의 영향을 미치는 것으로 나타났다. 또한 기본모형에서 기타포괄손익의 변동액과 누계액을 모두 구분한 확장검증모형은 높은 수정$R^2$ 값을 나타내며, 미실현손익항목인 기타포괄손익항목의 구분 공시정책은 회계정보의 유용성 측면에서 긍정적인 효과를 보일 수 있음을 시사해주었다. 그러나 여전히 미실현손익항목이 기업가치에 미치는 방향성 측면에서는 향후에 보다 세밀한 연구를 통하여 정보이용자입장에서는 이를 신중히 검토하고 고려해야 할 것으로 판단된다. 따라서 본 연구는 새로 제정된 IFRS 17의 도입에 따른 보험회사의 공정가치평가에 관한 정보유용성을 실증적 검증을 통하여 예상하고, 자본시장에 목적적합한 정보산출의 방향성을 제시하였다는데 의의가 있다. This study aims to verify the effects of unrealized gain or loss, that is the fair value evaluation item of insurance company's assets and liabilities, to capital markets focusing on fair value evaluation of insurance company's liabilities, which is the core of IFRS 17 that will be implemented in 2021. For this purpose we carried out regression analysis to verify the effects of changed other comprehensive income(OCI) and accumulated OCI, published in quarterly financial statements of listed insurance companies, on stock price utilizing Ohlson(1995)'s extended test model. The results of the empirical analysis are as follows. First, changed OCI showed a significant negative(-) effects on stock price. Second, accumulated OCI revealed a significant positive(+) effects on stock price. Furthermore, extended test model classifying changed OCI and accumulated OCI in a basic model represented the highest $R^2$ number and public announcement policy of OCI, a kind of unrealized gain or loss item, implied that it could give positive impact on accounting information. But still the direction that unrealized gain or loss affects on firm value must be carefully reviewed and considered in the future via more detailed study by the user of information. Therefore this study is meaningful in that it can predict usefulness of information on insurance company's fair value evaluation via empirical test accompanied by introduction of newly established IFRS 17 and it also can suggest direction of information production suitable for capital market.

성악심리치료활동을 통한 자기의식 변화에 관한 연구

이현주,Lee, Hyun Joo 한국음악치료교육학회 2007 인간행동과 음악연구 Vol.4 No.2

The purpose of this study is to learn both effects of the vocal psychotherapy on the self-consciousness and the variety of the self-consciousness on the vocal psychotherapy in return. The research for this study was performed to three subjects who were students of E university, Seoul, ten times for sixty minutes. The subjects were all volunteers for the advertisement on a music-therapy program searching for them on the web site of E university. The vocal psychotherapy program consists of four steps and each of them consists of two to four short terms again. Both before and after the experiment, examinations on self-consciousness were done to recognize the change of the subjects' self-consciousness which would be caused by the vocal psychotherapy activity. After every short term, the subjects were asked to write reports to closely analyze the change of self-consciousness according to the terms and the variety of the subjects. The effect of the vocal psychotherapy activity on the changes of scores in the self-consciousness examination is the first thing to point out on this study. There appeared some personal varieties on the total scores of the examination and scores of some sub-categories. Especially, there were different scores on the private self-consciousness, the public self-consciousness, and the social anxiety between before and after performing the vocal psychotherapy program. Subject A, who had got the best score of all on the scope of the private self-consciousness, showed the steepest decrease on the very scope. On the contrary, the subject showed decrease of scores of the public self-consciousness and the social anxiety in the relatively little rate. Subject B, who had got the highest score of the three on the public self-consciousness, showed the steepest decrease on that of all scopes and showed no difference on the social anxiety scope. In the case of the last one, subject C, who had relatively low scores on the private and public self-consciousness than the others, the private self-consciousness score increased but the public self-consciousness and the social anxiety scores decreased. The changes of the scores of each questions were examined in order to see possible other changes that had not been exposed on the changes of the total and sub-categories scores. As a result of that, of all twenty-eight questions, there were changes about one to two points. Subject A showed the difference with thirteen questions, subject B with sixteen and subject C with nineteen questions. The rate of change of subject C was relatively small but more questions changed and the change of score was wider than the others. Considering all those results, It can be possibly said that the vocal psychotherapy affects the changes of the scores of sub-categories in self-consciousness examination. The next thing to point out on this study is the change of recognition that was exposed on the subjects' report after every short term of the program. As a result of the close analyzing, according to the short terms and variety of self-consciousness, recognizing the way express subjects themselves by voice and recognizing their own voices appeared to be different. How much they cared about others and why they did so were also different. According to the self reports, subject A cared much about her inner thought and emotion and tended to concentrate herself as a social object. There appeared some positive emotional experiments such as emotional abundance and art curiosities on her reports but at the same time some negative emotions such as state-trait anxiety and neuroticism also appeared. Subject B, who showed high scores on the private and public self-consciousness like subject A, had a similar tendency that concentrates on herself as a social object but she showed more social anxiety than subject A. Subject C got relatively lower points in self-consciousness examination, tended to care about herself, and had less negative emotions such as state-tra 본 연구의 목적은 성악심리치료활동이 자기의식 수준 변화에 미치는 영향을 알아보고 자기의식 수준의 차이에 따라 자기보고서에 보고하는 내용이 어떻게 다른지를 알아보는 데에 있다. 본 연구는 서울시에 위치하고 있는 E 대학교에 재학 중인 여대생 3명을 대상으로 총 10회로 약 60분간 진행되었다. 연구에 참여한 이들은 음악치료 프로그램 지원자 모집에 자발적으로 지원한 자들이며, 연구에 사용된 성악심리치료 프로그램은 4단계로 구성되었다. 성악심리치료활동을 통한 대상자의 자기의식 수준 변화를 알아보기 위해 사전사후에 자기의식검사를 실시하였으며, 매 회기 성악심리치료활동을 마친 후 자기보고서를 작성하여 보고 내용의 변화를 분석하였다. 본 연구에서는 첫째로 성악심리치료활동이 자기의식검사 점수 변화에 미치는 영향을 알아보고자 하였다. 성악심리치료 프로그램의 실시 전후에 자기의식검사를 실시한 결과, 자기의식검사 전체 점수와 하위개념 점수가 개인별로 다른 변화를 보였다. 자기의식검사의 전체 점수와 하위개념 점수의 사전사후 점수에는 나타나지 않은 변화를 살펴보기 위해 문항별 변화를 알아본 결과, 총 28문항 중에서 대상자 A는 13개, 대상자 B는 16개, 대상자 C는 19개의 문항이 1-2점씩 변화하였다. 이는 점수의 변화율에는 나타나지 않은 결과로 위의 내용들을 종합하면, 성악심리치료활동이 자기의식검사의 하위개념 점수의 증감에 영향을 미친다는 결론을 유추할 수 있다. 둘째로는 매 회기를 마친 후 자기보고서에 보고된 내용의 분석을 통해 성악심리치료활동이 진행되는 동안 자기의식 수준의 차이에 따라 자기보고서에 보고하는 내용이 어떻게 다른지를 알아보고자 하였다. 질적 분석 결과, 자기의식의 개인차에 따라 자신을 목소리로 표현하는 것에 대한 인식, 자신의 목소리에 대한 인식, 타인이 의식되는 정도와 내용이 회기와 개인별로 다르게 나타났다. 분석된 자기보고서의 내용을 구체적으로 살펴보면, 사적자기의식 점수와 공적자기의식 점수가 상대적으로 높은 대상자 A는 자신의 내적 사고와 감정에 대한 측면을 많이 의식하고, 사회적 객체로서의 자신에게 주의를 집중하는 경향이 자기보고서에 많이 나타났다. 또한 감정적 풍부함, 예술적 호기심과 같은 긍정적 정서 경험과 함께 특성, 상태 불안, 신경증적 경향성 등의 부정적 정서도 많이 나타났다. 반면, 대상자 A와 함께 사적자기의식 점수와 공적자기의식 점수가 상대적으로 높은 B의 경우 사회적 객체로서의 자신에게 주의를 집중하는 경향은 A와 비슷하나, 다른 사람 앞에서 불안해하고 당황하는 사회불안 관련 경향이 많이 보고되었다. 마지막으로, 다른 참여자들에 비해 상대적으로 낮은 자기의식점수를 보이는 대상자 C는 대상자 A와 B에 비해 자신의 타인을 의식하는 경향이 상대적으로 적게 보고되었으며, 특성, 상태 불안과 같은 부정적 정서도 적게 보고되었다. 이 연구는 자기의식으로 인해 활성화되는 자기평가과정으로 인해 어려움을 겪는 이들을 위한 연구라는 점과 자기(Self)와 밀접하게 연관된 목소리를 주로 사용한다는 점, 그리고 기술적 어려움의 해소를 위해 성악기술훈련을 실시하였다는 점이 의미가 있다. 또한 성악심리치료활동을 통해 정신건강과 성격발달에 긍정적인 변화를 가져올 수 있다는 사실을 시사한다.

난치성 녹내장에서 아메드 녹내장밸브 삽입술의 임상적 고찰

이현주,최규룡,Hyun Joo Lee,Kyu Ryong Choi 대한안과학회 2006 대한안과학회지 Vol.47 No.6

Purpose: To assess the efficacy, safety, and clinical outcome of the Ahmed glaucoma valve implant in refractory glaucoma. Methods: We retrospectively studied 55 eyes of 55 patients who underwent Ahmed glaucoma valve implantation for refractory glaucoma unresponsive to conventional management. The mean follow-up period was 26.3±11.5 months. Surgical success was defined as an intraocular pressure between 5 and 21 mmHg regardless of glaucoma medication. Results: The reduction of intraocular pressure was statistically significant (p<0.05) and the number of glaucoma medications was decreased. The 1-year and 2-year success rates were 83.0% and 75.8%, respectively. Complications included hyphema in 9 eyes, hypotony with shallow anterior chamber in 2 eyes, choroidal detachment in 4 eyes, tube obstruction in 1 eye, tube migration in 2 eyes, and bullous keratopathy in 2 eyes. Conclusions: Ahmed glaucoma valve implantation may provide good intraocular pressure control in patients with refractory glaucoma unresponsive to conventional treatments, and may be effective for reducing the incidence of hypotony in the early postoperative period.

집단검진 환자에서 측정한 안구회선의 범위

이현주,임기환,Hyun-Joo Lee,M,D,Key-Hwan Lim,M,D 대한안과학회 2005 대한안과학회지 Vol.46 No.10

Purpose: To determine the range of cyclotorsion in the mass screening of patients by studying the spatial relationship between the optic disc and the fovea. Methods: We examined the horizontal and vertical distances from the center of the optic disc to the fovea using the fundus photographs of 249 subjects (498 eyes) without a past history of strabismus through mass screening and then calculated the optic disc-foveal angle. We studied the differences in all the measured parameters between the right and left eyes and between men and women. Results: The horizontal distance from the center of the optic disc to the fovea was 2.59±0.26 DD (disc diameter) in the right eye and 2.58±0.27 DD in the left eye. The mean horizontal distance was 2.59±0.26 DD. The vertical distance from the center of the optic disc to the fovea was 0.28±0.14 DD in the right eye and 0.30±0.13 DD in the left eye. The mean vertical distance was 0.29±0.14 DD. The calculated disc-foveal angle was 6.26±2.98 degrees in the right eye and 6.69±2.84 degrees in the left eye (mean, 6.50±2.92 degrees). There were no significant differences between the right and left eyes or between males and females. The 95% range of the location of the fovea was from 0.01 DD to 0.57 DD inferior to the optic disc center. Conclusions: We concluded that the clinical location of the fovea, as measured in the mass screening, extends from the center of the optic disc to the lower edge of the optic disc.

실험계획법을 이용한 동축 에어블로운 전기방사 공정의 최적화

이현주,최민기,박진희,김주용,Lee, Hyun Joo,Choi, Min Ki,Park, Jin Hee,Kim, Jooyong 한국섬유공학회 2014 한국섬유공학회지 Vol.51 No.1

In this study, a coaxial air-blown spinning system has been optimized for the variables of air flow rate, solution concentration, and voltage using the design of experiment (DOE) method. Both response surface analysis (RSA) and Taguchi's method (TM) were employed and compared to obtain the optimal process conditions. A total of 41 spinning trials were utilized and fitted with RSA and TM; they were then used to obtain mathematical prediction models. The resulting optimum parameters were an air flow rate of 20 l/min, a concentration of 8 wt%, and a voltage of 35 kV, predicting an average diameter of 335.76 nm with an estimated error of 18.85 nm. In TM, the SN ratio was calculated on randomly chosen data. The optimal process conditions that gave the largest SN ratio were an air flow rate of 20 l/min, a concentration of 8 wt%, and a voltage of 30 kV, representing the estimated SN ratio and diameter, -52.03 and 309.11 nm, respectively. For coaxial air-blown electrospinning under the same conditions, the experimental SN ratio and diameter were -52.0269 and 376.75 nm, respectively.