전침자극과 경피신경전기자극이 흰쥐 좌골신경 압좌손상 후 척수내 GAP-43 발현에 미치는 영향

이현민,박은세,김민희,김석범,김동현,김진상,Lee, Hyun-Min,Park, Eun-Se,Kim, Min-Hee,Kim, Souk-Boum,Kim, Dong-Hyun,Kim, Jin-Sang 대한물리치료학회 2006 대한물리치료학회지 Vol.18 No.1

Purpose: The purpose of this study was to identify the effect of electroacupuncture(EA) and transcutaneous electric nerve stimulation(TENS) after sciatic nerve crush injury in rats. Methods: The EA for experimental group I (Exp I, n=15) and TENS for experimental group II (Exp II, n=15) was applied from post-injury day(PD) 1 to PD 14 after sciatic nerve injury using low frequency stimulator that gave electrical stimulation(15min/60Hz). In order observe the effect of EA and TENS, this study examined GAP-43 expression in rat lumbar spinal cord at the PD 1, PD 7 and PD 14. In addition, the stride length(SL) and toe out angle(TOA) were measured at the PD 7 and PD 4. Results; Exp I and Exp II had higher GAP-43 immunoreactivity than control group(PD 1, 7, 14). The SL of Exp I and Exp II were significantly higher than control group(PD 7, 14). The TOA of Exp I and Exp II were significantly lower than control group(PD 7, 14). Conclusion: EA and TENS application increased motor nerve recovery and expression of GAP-43 immunoreactivity after sciatic nerve crush injury. Therefore effect of TENS and EA had similar effect on nerve regeneration and functional recovery.

수술현미경에서의 다중형광영상을 이용한 뇌종양과 혈관영상 검출 시스템 연구

이현민,김홍래,윤웅배,김영재,김광기,김석기,유헌,이승훈,신민선,권기철,Lee, Hyun Min,Kim, Hong Rae,Yoon, Woong Bae,Kim, Young Jae,Kim, Kwang Gi,Kim, Seok Ki,Yoo, Heon,Lee, Seung Hoon,Shin, Min Sun,Kwon, Ki Chul 한국광학회 2015 한국광학회지 Vol.26 No.1

본 연구에서는 뇌 종양 수술에서 다수의 광원과 빔 스플리터 모듈을 사용해 종양과 혈관의 형광영상을 동시에 검출하고 획득한 형광영상을 동일한 디스플레이 장치에 표시함으로써 시술자에게 종양과 혈관의 정확한 정보를 실시간으로 제공할 수 있는 현미경 시스템을 제안한다. 5-ALA(5-Aminolevulinic acid) 와 ICG(Indocyanine green) 의 형광영상의 동시 검출을 위해 빔 스플리터(beam-splitter : BS)모듈을 사용하였고 5-ALA는 600nm, ICG는 800nm이상의 파장 대역에서 가장 효율이 뛰어나도록 구성하였다. 빔 스플리터 모듈은 파장 대역에 따라 광학기기의 구조를 변경할 수 있고 필터를 탈, 착 가능한 구조로 설계하여 필요에 따라 빔 스플리터와 필터의 종류를 변경할 수 있으며 5-ALA 및 ICG 이외의 형광염료를 사용한 시술에서 사용할 수 있다. 빔 스플리터 모듈을 통한 형광영상은 5-ALA는 가시광역, ICG는 근적외선 영역을 검출 할 수 있는 CCD 카메라를 장착해 동일한 디스플레이에서 확인할 수 있고 획득한 형광영상은 닮음 변환(similarity transform)을 이용해 원영상과 정합하여 실시간으로 시술자에게 제공하는 시스템을 구현하였다. In this paper, we propose a microscope system for detecting both a tumor and blood vessels in brain tumor surgery as fluorescence images by using multiple light sources and a beam-splitter module. The proposed method displays fluorescent images of the tumor and blood vessels on the same display device and also provides accurate information about them to the operator. To acquire a fluorescence image, we utilized 5-ALA (5-aminolevulinic acid) for the tumor and ICG (Indocyanine green) for blood vessels, and we used a beam-splitter module combined with a microscope for simultaneous detection of both. The beam-splitter module showed the best performance at 600 nm for 5-ALA and above 800 nm for ICG. The beam-splitter is flexible to enable diverse objective setups and designed to mount a filter easily, so beam-splitter and filter can be changed as needed, and other fluorescent dyes besides 5-ALA and ICG are available. The fluorescent images of the tumor and the blood vessels can be displayed on the same monitor through the beam-splitter module with a CCD camera. For ICG, a CCD that can detect the near-infrared region is needed. This system provides the acquired fluorescent image to an operator in real time, matching it to the original image through a similarity transform.

미세전류치료가 류마티스 관절염 유발 흰쥐의 Interleukin-1 발현에 미치는 영향

이현민,채윤원,Lee, Hyun-Min,Chae, Yun-Won 대한물리치료학회 2009 대한물리치료학회지 Vol.21 No.2

Purpose: Electrical stimulation is one of several treatments recommended for RA patients. Electrical stimulation of RA patients, reduces pain, or facilitates joint motion prior to exercises. However, there is still limited evidence on the efficacy of electrical stimulation and thus any conclusions drawn about this method remain controversial. Recently, Microcurrent Electrical Neuromuscular Stimulation (MENS) has received significant attention as a potential method of electrical stimulation. In this study, we investigated the effect of microcurrent treatment in rheumatoid arthritis rat. Methods: Subjects were allocated either to the control group or experimental group, which was subject to microcurrent stimulation. Interleukin-1 expression in the metatarsophlangeal joint and the oedema index in the ankle were used for classification and subsequent evaluation of pathology. Subjects were assessed at 1, 7 and 14 days after inducing rheumatoid arthritis through adjuvant injection. Thirty-six subjects, 18 in each group, were used in this study. Statistical analysis was performed by calculating the differences between the two groups and between each interval assessment. Categorical variables were compared between the two groups with the paired-T test. The one-way ANOVA test was performed to assess changes in ordinal variables. Results: Baseline characteristics were similar in both groups. Statistically significant differences were found between the two groups. The biological marker of pro-inflammatory cytokine and oedema index were decreased in response to this treatment. Conclusion: These data show that treatment of rheumatoid arthritis with a microcurrent stimulation device reduced the oedema index and pro-inflammatory cytokine IL-1.

반응소결된 Si₃N₄-SiO₂-BN 복합체의 기계적 강도 및 유전물성에 관한 연구

이현민,이승준,백승수,김도경,Lee, Hyun Min,Lee, Seung Jun,Baek, Seungsu,Kim, Do Kyung 한국세라믹학회 2014 한국세라믹학회지 Vol.51 No.5

Silicon nitride ($Si_3N_4$) is regarded as one of the most promising materials for high temperature structural applications due to its excellent mechanical properties at both room and elevated temperatures. However, one high-temperature $Si_3N_4$ material intended for use in radomes has a relatively high dielectric constant of 7.9 - 8.2 at 8 - 10 GHz. In order to reduce the dielectric constant of the $Si_3N_4$, an in-situ reaction process was used to fabricate $Si_3N_4-SiO_2$-BN composites. In the present study, an in-situ reaction between $B_2O_3$ and $Si_3N_4$, with or without addition of BN in the starting powder mixture, was used to form the composite. The in-situ reaction process resulted in the uniform distribution of the constituents making up the composite ceramic, and resulted in good flexural strength and dielectric constant. The composite was produced by pressure-less sintering and hot-pressing at $1650^{\circ}C$ in a nitrogen atmosphere. Microstructure, flexural strength, and dielectric properties of the composites were evaluated with respect to their compositions and sintering processes. The highest flexural strength (193 MPa) and lowest dielectric constant (5.4) was obtained for the hot-pressed composites. The strength of these $Si_3N_4-SiO_2$-BN composites decreased with increasing BN content.

공동주택 상품의 고객서비스 개선 전략 연구

이현민,이동훈,김선국,Lee, Hyun-Min,Lee, Dong-Hoon,Kim, Sun-Kuk 한국건축시공학회 2009 한국건축시공학회지 Vol.9 No.5

As customers are becoming increasingly important in corporate management, there is a growing demand for migration to customer-focused organizational structures. Unlike the manufacturing industry, the construction industry is non-iterative and non-standardized. As a result, a wide variety of materials, human resources, technologies and equipment must be mobilized in complex work activities to complete a structure. Consequently, surprises are bound to occur as such work activities progress. This paper intends to study a strategy that is designed to improve customer services for apartment building units. It aims primarily to focus on cost control and brand management. Housing tenants and industry experts are surveyed to collect input for issue analysis. In addition, the external circumstances and internal capabilities of major builders in Korea are analyzed, and a SWOT analysis is performed regarding market conditions related to customer service. These analysis results are utilized to develop a strategy implementation plan over different time frames, and the operational resources available for such strategy implementation are analyzed in order to forecast its performance. This research will facilitate communication between construction companies in Korea and their customers by proposing a customer service improvement strategy for apartment building units, and is expected to provide resource material for a strategic analysis of efforts to fully incorporate customer requirements 고객의 중요성이 지속적으로 증대됨에 따라 조직 구조를 고객 중심 구조로 전환해야 한다는 요구가 증대되고 있다. 건설업은 제조업과는 달리 비 반복적이고 비표준화의 업무특성을 가지고 있으므로 하나의 건축물을 완성하기 위하여 다양한 자재, 인력, 기술, 장비 등을 투입하여 복합적인 업무를 수행하게 된다. 따라서 이러한 업무를 추진하는데 있어서 예기치 못했던 상황들은 쉽게 발생하기 마련이다. 본 연구의 목적은 비용 관리 및 브랜드 관리를 통하여 공동주택 상품의 고객서비스를 개선하기 위한 전략을 연구하는 것이다. 본 연구를 위해 공동주택을 중심으로 고객서비스 및 경영전략에 대한 경영학적 정의와 개념을 정리하고, 문제점 분석을 위하여 주택 입주 고객과 전문가집단을 대상으로 설문조사를 실시한다. 또한 국내 주요 건설 회사들의 외부 환경 및 내부 역량을 분석하고, 고객서비스의 시장상황을 반영하여 SWOT 분석을 실행한다. 이를 통하여 기간별 전략 추진계획을 세우며, 전략추진 경영자원을 분석하여 전략의 성과를 예측한다.

Disciplinary Health Education : 정신지체아의 신체조정력 향상도에 관한 연구

이현민,홍양자 ( Hyun Min Lee,Yang Ja Hong ) 한국체육학회 1994 국제스포츠 학술대회 Vol.1994 No.-

타워크레인의 횡지지 최적설계 알고리즘 개발

이현민,호종관,김선국,Lee, Hyun-Min,Ho, Jong-Kwan,Kim, Sun-Kuk 한국건설관리학회 2010 한국건설관리학회 논문집 Vol.11 No.1

예측 불가능한 자연 재해를 포함하여 현장관리자의 장비 설치 및 운영 시의 경험부족은 타워크레인과 같은 대형양중장비에 심각한 사고의 원인으로 작용한다. 국내에서는 2003년 태풍 "매미"의 영향으로 불안정한 지지구조를 가진 약 50여대의 타워크레인이 전복되는 사고가 발생하였으며, 아직까지 많은 현장관리자는 대형양중장비에 대한 설치 및 운영에 대한 이해가 부족하여 예산을 실행하는 데 비효율적인 모습을 보이고 있다. 또한, 최근 들어 초고층 건설 프로젝트가 급격하게 증가함으로써 타워크레인의 사용빈도 또한 증가하고 있으므로, 이로 인한 타워크레인 기초판의 지지 안정성뿐만 아니라 횡지지 안정성을 검토하는 것이 요구되고 있다. 본 연구의 목적은 타워크레인의 횡지지 최적설계 알고리즘을 개발하는 것으로, 타워크레인 횡지지의 구조적인 안정성을 확보하고 비용이 최소화되는 부재조합을 선택하여 현장에 적용 가능하게 한다. 이는 향후 현장관리자의 타워크레인 설치 및 운영 업무를 효율적으로 증진시킬 것이다. Poor expertise in equipment operation and installation, coupled with unpredictable natural disaster, usually directly leads to disastrous accidents of large lifting equipment such as tower cranes. For example, 52 tower cranes fell down due to the unstable support in Korea at the attack of Typhoon "Maemi" in 2003, which damaged property and caused loss of life. In high-rise construction projects, top-slewing or luffing-jib tower cranes needs checking the stability of lateral-support in addition to the bottom support such as the foundation. In this study, the optimization algorithm for lateral-support of tower cranes is conducted, which is expected to enhance the structural stability of tower cranes and save the cost in conflict with the safety.

만 $9{\sim}12$세 남자 아동의 머리와 얼굴 부위 측정 및 유형 분류

이현민,최혜선,김선희,Lee Hyun-Min,Choi Hei-Sun,Kim Son-Hee 복식문화학회 2004 服飾文化硏究 Vol.12 No.6

This study was aimed to provide the fundamental and various measurement data of the head and face for male children. Two hundred forty one male children, aged nine to twelve years, participated for this study. The 31 regions on the head and face of the subjects were directly measured by the expert experimenters. Through factor analysis, the six factors were extracted upon factor scores and those factors comprised $67.47\%$ for the total variances. The first factor was described the general height elements for the mouth and the environs of the mouth. The second factor was described the general height around the nose, forehead and eyes. The third factor was described the height of the ear environs. The forth factor contained the length around the sinciput to the occiput, the head thick and the head circumstance. The fifth factor was described the general width of the outer head and the corner of the eyes. The last factor contained the depth of the mouth and nose. Four clusters as their head and face shape were categorized using six factor scores by cluster analysis. Type 1 was characterized by the shortest head and face width, surface length and girth, and the shorter length of head, but the highest position of chin, philtrum, upper lip. Type 2 was characterized by the shortest head and face length and thickness, and the lowest position of the forehead, eye, nose, mouth, ear environs, but that had wider width of head and face. Type 3 was characterized by the longest and the widest head and face type, and the highest position of the mouth. Type 4 was characterized by longer length of head and face, and the widest head girth and largest head thickness, and the highest position of the forehead, eye, nose environs. And this type had the widest width of nose and mouth, and the longest head surface length.

PES 기판 위에 증착된 Mg_0.3Zn_0.7O 박막의 산소압에 따른 구조 및 광학적 특성

이현민,김상현,장낙원,김홍승,Lee, Hyun-Min,Kim, Sang-Hyun,Jang, Nakwon,Kim, Hong-Seung 한국전기전자재료학회 2014 전기전자재료학회논문지 Vol.27 No.11

MgZnO has attracted a lot of attention for flexible device. In the flexible substrate, the crystal structure of the thin films as well as the surface morphology is not good. Therefore, in this study, we studied on the effects of the oxygen pressure on the structure and crystallinity of $Mg_{0.3}Zn_{0.7}O$ thin films deposited on PES substrate by using pulsed laser deposition. We used X-ray diffraction and atomic force microscopy in order to observe the structural characteristics of $Mg_{0.3}Zn_{0.7}O$ thin films. The crystallinity of $Mg_{0.3}Zn_{0.7}O$ thin films with increasing temperature was improved, Grain size and RMS of the films were increased. UV-visible spectrophotometer was used to get the band gap energy and transmittance. $Mg_{0.3}Zn_{0.7}O$ thin films showed high transmittance over 90% in the visible region. As increased working pressure from 30 mTorr to 200 mTorr, the bandgap energy of $Mg_{0.3}Zn_{0.7}O$ thin film were decreased from 3.59 eV to 3.50 eV.

성문암으로 오인되기 쉬운 원발성 후두 아스페르길루스증 1예

이현민,정광태,김정석,한주희,Lee, Hyun Min,Jung, Kwang Tae,Kim, Jung Suk,Han, Ju Hee 대한후두음성언어의학회 2013 대한후두음성언어의학회지 Vol.24 No.2

Infection by aspergillus, which is a kind of mold, or a filamentous fungus, occurs rarely in larynx. Furthermore, primary laryngeal aspergillosis without any other airway tract extension and without any generalized immune deficit is extremely rare. We present a case of primary aspergillosis on vocal cord in a 72-year-old male who had no history of immune deficiency, voice abuse or steroid use.