온라인 커뮤니티의 사회적 자본과 제도 – 디시인사이드 바람의 화원/바람의 나라 갤러리를 중심으로

이헌아,류석진 한국정보사회학회 2013 정보사회와 미디어 Vol.- No.27

본 논문은 온라인 커뮤니티의 제도를 ‘재생산’이라고 보고, 제도의 성패가 사회적 자본에 의해 달라진다는 가설을 검증하는 목표를 갖고 있다. 이를 위해 이론적으로 로버트 퍼트남(Robert D.Putnam)의 ‘사회적 자본(social capital)' 개념을 소개하고, 다른 연구를 통해 측정 가능하도록 개념을 보완한 뒤, 이를 온라인 커뮤니티에 맞게 수정 및 적용했다. 구체적으로 가설을 검증하기 위해 비슷한 시기에 나타났으나 양상은 크게 달랐던 두 온라인 커뮤니티를 선정하여 NodeXL 프로그램을 이용, 사회적 자본에 대한 실증적인 분석을 하였다. 본 논문은 온라인 커뮤니티에도 사회적 자본 개념을 적용할 수 있다고 보았으며, 온라인 커뮤니티의 제도인 재생산에 영향을 끼치는 사회적 자본의 구성요소를 탐구했다. 또한 온라인 커뮤니티에 맞는 사회적 자본 개념이 기존과는 다를 수 있음을 지적하고 있다.

Isolated Non-Compaction of the Left Ventricle in a Patient with New-Onset Heart Failure: Morphologic and Functional Evaluation with Cardiac Multidetector Computed Tomography

이헌,김석연,U. Joseph Schoepf 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.2

We describe a case of new-onset heart failure in a patient in whom cardiac CT enabled the non-invasive diagnosis of isolated non-compaction and associated functional abnormalities of the left ventricle with the concomitant evaluation of coronary arteries. This case highlights the utility of cardiac CT for the morphological and functional evaluation of the heart as a single imaging modality.

접힘 인공수정체 표면의 폴리에틸렌 글리콜 표면 중합이 후낭혼탁 발생에 미치는 영향

이헌일,김미금,고정화,이현주,위원량,이진학.Hyeon Il Lee. M.D... Mee Kum Kim. M.D.. Ph.D... Jung Hwa Ko... Hyun Ju Lee... Won Ryang Wee. M.D.. Ph.D... Jin Hak Lee. M.D.. Ph.D.. 대한안과학회 2006 대한안과학회지 Vol.47 No.4

Purpose: To investigate the effect of polyethylene glycol (PEG)-grafted acryl intraocular lenses on the prevention of posterior capsular opacification (PCO). Methods: The acrylic surface of an intraocular lens (Acrysof SA 60AT, Alcon) was polymerized with PEG (PEG-IOL). To investigate the degree of cell adhesion to the modified lens surface, human lens epithelial cells (1×104 cells/ml) were inoculated on each PEG-grafted and acrylic control lens, and all were cultured in a carbon dioxide incubator for 24 hours. The adhered cells were trypsinized and counted. The PEG-IOL was implanted in 20 New Zealand rabbits after removal of the crystalline lens. The formations of PCO were checked serially through retroilluminated digital photography and severity scores were calculated using POCOman. The cell adherence pattern on the PEG-grafted IOL was examined by scanning electron microscopy. Results: The mean number of adherent cells in PEG-IOL was 3.2±1.1×103, which tended to be smaller than that of the unmodified acrylic control (3.6±1.9×103), but without statistical significance. The mean severity of posterior capsular opacification in PEG-IOL was much lower than in the control, especially at week 3. Scanning electron microscopy revealed more patch-like cells firmly attached to the lens surface in the control. Conclusions: PEG polymerization of the acrylic IOL may lessen the formation of posterior capsular opacification.

Overview of Phase change memory

이헌 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.1

This coming 21st century is a digital era based on information revolution. All of human being``s intellectual products will be reformed as the form of digital format which is represented as the combination of ``0`` and ``1`` and they will be transferred from the place to the place in a blink of time. In order to realize such a drastic change, new information storage technology must be invented. It also means that the invention of new materials and devices for improved information storage must be followed. Due to the new emerging markets of personal digital devices, including PDA, digital camera/camcoder, cellular phone, MP3 player and e-book reader, flash memory market is continuously increasing. However, flash memory has somewhat fatal disadvantages such as high voltage operation, limited endurance and slow write/read speed and thus there are various efforts to replace flash memory device to new improved non-volatile memory. Among new non-volatile devices, PCRAM is regarded as one of the most promising non-volatile memory device which can replace the flash memory. In this presentation, operation principle, advantages and disadvantages of phase change memory will be explained and be compared with MRAM and FRAM.

건강관리코너 - 봄철. 황사와 눈. 건강

이헌일,Lee, Heon-Il 한국화재보험협회 2006 防災와 保險 Vol.113 No.-

언제부터인가 우리는 도시 공해와 더불어 결코 유쾌하지만은 않은 바다 건너온 손님들에 의해 건강을 위협받고 있다. 바로 중국, 내몽골 지역의 사막화로 인해 겨우내 얼어 붙었던 흙이 봄바람을 만나 생기는 황사가 그 주범이다. 비록 황사가 토지의 산성화를 막아 농작물이 잘 자라는 데 도움을 준다는 말도 있지만, 요재 불어오는 황사는 중국의 산업화에 힘입어 공해물질을 다량 함유한 먼지이기에 더욱 그 피해가 심각하다. 대표적으로 인체의 호흡기에 침입하여 여러 문제를 일으키고 눈이나 피부에도 질환을 일으킬 수 있다. 즉 황사는 눈을 직접 자극하여 결막염의 증세를 일으킬 뿐만 아니라, 함유된 여러 중금속과 같은 물질들에 의해 알레르기성 질환도 유발할 수 있다는 뜻이다.

A Case Report of Congenitally Corrected Transposition of Great Arteries: Morphologic and Functional Evaluation with Cardiac CT

이헌,박병원 대한영상의학회 2013 대한영상의학회지 Vol.69 No.3

Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital anomaly characterized by atrioventricular and ventriculoarterial discordance. We report a case of new-onset heart failure in a 69-year-old female in whom cardiac CT demonstrated ccTGA without the associated cardiovascular anomalies. In this case, cardiac CT was useful for elucidating the rare and unexpected congenital etiologies of abrupt-onset heart failure in an old patient by the simultaneous evaluation of cardiac morphology and function as a single study (inserted).

Tumor Necrosis Factor from Human Peripheral Monocytes: Induction, Purification, Gene Cloning and Expression

이헌,김정현,김승수,Lee, Hun,Kim, Jeong-Hyun,Kim, Soung-Soo 생화학분자생물학회 1989 한국생화학회지 Vol.22 No.4

LPS와 PMA를 다양하게 조합하여 사람 단핵구 세포를 처리해서 이들로부터 사람 종양괴사인자가 생성되었다. 특히 사람 단핵구 세포 ($2{\times}10^7$ 세포/ml)를 PMA (10 ng/ml)로 먼저 6시간 처리하고 LPS $(20{\mu}g/ml)$로 나중에 6시간 처리하였을 때 가장 높은 종양괴사인자 활성을 얻을 수 있었다. 유도한 종양괴사인자는 혈청이 포함되지 않은 배양배지로부터 DEAE-Sephacel 이온교환 크로마토그라피, Sephadex G-75 gel filtration, SDS-PAGE 용출방법에 의해 정제하였다. SDS-PAGE 방법에 의해 결정된 종양괴사인자의 분자량은 대략 17,800 정도였고 Sephadex G-150 gel filtration 방법에 의해 얻은 native 분자량은 68,000 정도였다. 반면에 ${\lambda}gt11$ 발현 운반체 system에 의해 E. coli에서 발현된 recombinant 사람 종양괴사인자의 분자량은 Western blot 분석과 Sephadex G-150 gel filtration 방법에 의해 모두 17,400 정도로 나타났다. 이 같은 결과들로 보아 종양괴사인자의 monomer 형태와 multimer 형태가 모두 생물학적으로 활성을 갖는다는 것을 알 수 있다. Human tumor necrosis factor(TNF) was produced from human peripheral monocytes by treatment of the cells with various combinations of lipopolysaccharide(LPS) and phorbol myristate acetate(PMA). The best induction of TNF activity could be achieved when human peripheral monocytes ($2{\times}10^7$ cells/ml) were first treated with 10 ng/ml of PMA for 6 hours followed by 6 hours treatment with LPS$(20{\mu}g/ml)$. Induced TNF from serum-free culture media was purified by DEAE-Sephacel ion exchange chromatography, Sephadex G-75 gel filtration and SDS-PAGE elution. The molecular weight of the TNF as determined by SDS-PAGE was about 17,800, while the native molecular weight obtained by Sephadex G-150 gel filtration was 68,000. On the other hand, the molecular weight of recombiant human TNF obtained in E. coli by ${\lambda}gt11$ expression vector system was estimated to be 17,400 by Western blot analysis and Sephadex G-150 gel filtration. These results suggest that both monomeric and multimeric forms of TNF are biologically active.

176. 장루 합병증에 관한 임상적 분석

이헌,오재환 대한외과학회 1999 대한외과학회 학술대회 초록집 Vol.1999 No.11

Fractional Laser Photothermolysis for Treatment of Facial Wrinkles in Asians

이헌,윤진숙,이상열 대한안과학회 2009 Korean Journal of Ophthalmology Vol.23 No.4

Purpose: To evaluate the safety and efficacy of fractional photothermolysis (FP) in the treatment of facial wrinkles in Asians. Methods: A total of 27 Korean patients (Fitzpatrick type Ⅲ or Ⅳ) received 2-3 FP treatment sessions (Sellas; Dinona Inc., Seoul, Korea) spaced two weeks apart. Treatments were performed at settings of 7 to 9 mJ/microthermal treatment zone (MTZ) and a density of 1000 MTZ/㎠. Standardized digital photographs were obtained before each treatment and three months after the final treatment. The evaluations of clinical photographs were performed by three physicians blinded to the study subjects using a five-point grading scale. In addition, the patients’ perceived degree of improvement was assessed three months after the final treatment using a five-point grading scale. Side effects were monitored at each follow-up visit. Results: The physicians’ assessed degrees of improvement were excellent in three patients (12%), significant in ten (40%), and moderate in seven (28%). The patients’ self-assessed degrees of improvement were excellent in five patients (20%), significant in 11 (44%), and moderate in six (24%). Adverse events were limited to transient pain, erythema and edema, except in one case of transient postinflammatory hyperpigmentation. Conclusions: FP is an effective treatment modality for reducing facial wrinkles with minimal side effects in Asian patients.

사람 단핵구 종양괴사인자의 유도 , 정제 . 크로닝 및 발현

이헌,김정현,김승수 ( Hun Lee,Jeong Hyun Kim,Soung Soo Kim ) 생화학분자생물학회 1989 BMB Reports Vol.22 No.4

The gene encoding subtilisin Carlsberg from Bacillus licheniformis has been isolated by the $quot;in-situ colony hybridization technique$quot; using synthetic oligonucleotide as a probe. Pstl digested chromosomal DNA was ligated into the Pstl site of pBR322. The ligation mixture was used to transform E. coli and the transformants were screened by the in-situ colony hybridization technique. Out of 3,500 colonies screened, one colony was hyridized to the probe. The recombinant DNA of this positive clone was named pS113. Digestion of pS113 by restriction endonucleases showed that the size of the inserted DNA was about 4.6 Kb and the restriction map was nearly like that of Jacobs`. To express the gene in Bacillus, Pstl digested pS113 was ligated into the Pstl site of pMK4. The ligation mixture was used to transform B. licheniformis and the transformants were assayed on casein plate for protease secretion. We obtained a clony having a distinctively large halo.