선천성 생식기기형에 관한 임상적 고찰

박영선,이치중,성낙구,김흥용 대한산부인과학회 1991 Obstetrics & Gynecology Science Vol.34 No.4

1976년 1월부터 1989년 4월까지 14년 4개월간 서울을지병원 산부인과에 입원한 환자 25,601명중 자궁기형 24예, 질기형 7예를 발견하여 다음과 같은 결론을 얻었다. 1. 자궁기형은 입원환자 1,070명당 1예(0.09%)가 발견되었으며 쌍각자궁이 79%, 중격자궁이 21%였다. 2. 질기형은 입원환자 3,657명당 1예(0.03%)가 발견되었으며 질 형성부전이 29%, 질 중격이 71%였다. 3. 자궁기형의 진단은 개복술, 자궁난관조영술, 제왕절개술 등이 21~29% 비율로 이용되었으며 질기형은 모두 단순사진과 골반내진으로 진단되었다. 4. 선천성기형 환자가 병원을 찾게되는 주된 이유로는 산전진찰이 33%로 가장 높았으며, 이상 질 출혈 13%, 골반통, 1차성 불임증이 각각 10%, 무월경, 2차성 불임증이 각각 6%이었다. 5. 인공유산을 제외한 총 53회의 임신중 유산이 27회(51%), 조산이 2회(3.8%)였으며 태아손실율은 쌍각자궁이 51%, 중격자궁이 85.7% 질 중격이 40%이었다. 6. 만삭임부 10예중 4예(40%)가 둔위, 1예(10%)가 횡위였으며 신생아의 선천성 기형이나 태반조직의 잔류는 없었다. 7. 자궁성형술은 9예에서 실시했는데 1예에서 건강한 남아를 출산했으며 2예는 현재 임신중이고 3예는 계속 관찰중이다. 8. 질 형성부전 2예는 Mc-Indoe씨 수술을 시행하여 만족스런 결과를 얻었고 질 중격 2예는 중격을 제거하였다. The genital tract anomalies are rare but it can cause primary amenorrhea, infertility, recurrent abortion and other obstetrical complication. So the authers reviewed the 31 patients` medical records who were diagnosed as genital tract anomaly from January 1976 to April 1989 in Seoul Eul-Ji General Hospital Obstetrics and Gynecology department. And thereform, we summarized the results as follows: 1. Incidence of uterine anomaly was 0.09%(24 cases/25601 admission patients) and bicornuate uterus was 19 patients(79.2%), septate uterus was 5 patients(20.8%). 2. Incidence of vaginal anomaly was 0.03%(7 cases/25601 admission patients) and vaginal agenesis was 2 patients(28.6%), longitudinal vaginal septum was 3 patients(42.8%), transverse vaginal septum was 2 patients(28.6%). 3. The main diagnostic methods of uterine anomaly were laparotomy, hysterosalpingogram, cesarean section(21~29% of each other), and vaginal anomaly was diagnosed by simple inspection and pelvic examination. 4. The most common symptom was asymptomatic(33%) and vaginal spotting, pelvic pain, primary infertility were common problem(10~13% of each other). 5. Incidence of spontaneous abortion was 51%(27 cases/53 total pregnancies), preterm delivery was 3.8%(2 cases/53 total pregnancies) in uterine anomaly. The fetal wastage was 51% in bicornuate, 85.7% in septate, 40% in vaginal septum. 6. 4 breech presentations and 1 transverse lie were noted in 10 observed full term pregnancies. 7. The metroplasty was performed in 9 patients and thereafter one patient had one healthy baby, two patients are now in pregnancy without any complication. 8. The two patients of vaginal agenesis has been in good sexual life after Mc-Indoe operation and two cases of vaginal septum were resected.

학술정보 1 : 논문 번역 ; 중의학의 인류의학에서의 지위와 작용

이치중,박현식(역) 대구한의대학교 제한동의학술원 2004 東西醫學 Vol.29 No.2

난소종양의 조직병리학적 및 임상 고찰

홍서유,김병선,이치중,성영미 대한산부인과학회 1991 Obstetrics & Gynecology Science Vol.34 No.1

1983년 7월부터 1988년 6월까지 만 5년간 서울을지병원 산부인과에서 입원하여 난소종양으로 진단된 환자중 수술에 의해 제거된 조직의 병리조직학적검사로서 난소종양으로 확인된 148예에 대하여 임상 및 병리학적, 통계학적으로 비교, 관찰한 결과는 다음과 같다. 1. 전 난소종양중 비종양성 난소낭이 59예로 39.9%, 양성종양이 77예로 52.0%, 악성종양은 10예로 8.1%이었다. 2. 비종양성 난소낭의 경우는 황체낭포가 22예로 37.3%를 나타내 가장 많았으며 진성 난소종양에서는 낭성종양이 98.7%이었고 충실성 종양이 1.3%이었다. 양성종양에서는 낭성기형종이 44예로 57.2%, 장액성 낭선종이 20예로 26.0%, 점액성 낭선종이 12예로 15.5%의 빈도를 나타냈으며, 악성종양은 점액성 낭성선암이 6예 50.7%, 장액성 낭성선암이 2예 16.7%, 과립막 세포종이 3예로 25.9%의 빈도로 나타났다. 3. 조직병리학적으로 분류하면 난소상피세포에서 유래한 종양이 난소종양의 45%를 점하였으며, 그 중 점액성 낭선종이 20예로 가장 많았고 배세포에서 유래한 종양은 양성낭성기형종으로 49.5%이었으며 생식선 기질에서 유래한 종양은 과립막 세포종이 3예, 섬유종이 1예 관찰되었다. 4. 연령분포를 보면, 비종양성 난소낭은 30대가 42.4%, 40대가 30.5%의 분포로 평균연령이 36.5세였으며 양성종양에서는 30대가 37.7%, 20대가 27.3%로 평균연령이 34.7세이었다. 악성종양은 40대가 호발하여 58.3%로 평균연령이 44.5세이었다. 5. 난소종양의 크기는 비종양성 난소낭과 양성종양에서 직경 6~10 cm인 경우가 각각 55.9%, 62.9%로 평균직경이 7.2 cm, 9.4 cm이었으며 악성종양에서는 16~20 cm이 50%로 평균직경이 14.3 cm이었다. 6. 난소종양의 양측성은 비종양성 난소낭이 5.1%, 양성종양이 14.3%, 악성종양이 16.7%의 빈도를 나타내었다. 7. 주요 임상증상은 복부동통 및 불편감이 41.1%로 가장 많았고 복부종괴촉지, 이상질출혈의 순이었다. 8. 임신과 동반된 경우는 총 148예중 14예로 9.5%였으며 그 중에서 양성 낭성기형종이 5예, 35.7%로 가장 많았다. 9. 난소종양의 합병증은 총 18예에서 발생하였는데 파열이 10예로 6.8%, 염전이 6예로 4.1%, 염증성 변화가 2예로 1.4%에서 관찰되었다. The ovarian tumors are one of the many neoplasms seen in practice of Gynecology. A clinicopathological as well as statistical survey was on a series of 148 cases of the ovarian tumors which were operated and confirmed with postoperative histopathological study at the department of obstetrics and gynecology of Eul Ji hospital, Seoul during a period of 5 years from July, 1983 to June 1988. The results obtained are as follows; The incidence of true neoplastic tumor was 60.1% of all ovarian tumors which comprising 52.0% of benign and 8.1% of all malignant tumors. The corpus luteal cyst was the most frequent cyst among the non-neoplastic tumors. In benign neoplastic tumor, benign cystic teratoma was ranked first as 57.2%, followed by serous cystadenoma and mucinous cystadenoma comprising 26.6% and 15.5% respectively. In malignant tumors the incidence of mucinous cystadenocarcinoma and serous cystadenocarcinoma were 50.7% and 16.7%. On histopathological classification, the tumors originated from common epithelial cell were 45.0%, germ cell tumors were 49.5%, and sex cord stromal tumors were 4.5%. Mean age of non-neoplastic ovarian tumors were 36.5 years, that of benign tumors was 34.7 years and that of malignant tumors was 44.5 years. As to the subjective symptoms of all ovarian tumors. lower abdominal pain and discomfort was noted in 41.1%, palpable mass in the lower abdomen in 14.7% and vaginal bleeding in 14.7%. The ovarian tumors associated with pregnancy were 14 cases(9.5%), and the most common tumors were cystic teratoma as 35.7%

제 65 차 춘계학술대회 : 초록보고 ; 여성생식기의 선천성기형에 대한 임상적 고찰

성낙구,이치중,김홍룡,박영선 대한산부인과학회 1990 춘계학술대회 Vol.- No.-

여성생식기의 선천성기형에 대한 임상적 고찰

성낙구,이치중,김흥룡,박영선 대한산부인과학회 1990 대한산부인과학회 학술대회 Vol.65 No.-

Efficiency Tuning of UVA/UVB Absorbance through Control over the Intramolecular Hydrogen Bonding of Triazine Derivatives

최은영,이치호,전병선,남은비,정회중,이상욱 대한화학회 2018 Bulletin of the Korean Chemical Society Vol.39 No.7

난소 점액낭종파열에 합병된 복막 위점액중 1 예

유정옥,홍서유,이치중,조윤호 대한산부인과학회 1991 Obstetrics & Gynecology Science Vol.34 No.6

저자 등은 최근 서울을지병원 산부인과에서 74세된 환자에서 우측 난소의 경계성 점액성 낭선종에 동반된 복막 위점액종의 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Pseudomyxoma peritonei refers to the process of mucinous ascites secondary to mucinous tumor of intra-abdominal organs. It is often associated with mucinous tumors of the ovary, mucocele of the appendix and carcinoma of the large bowel. Pseudomyxoma peritonei is secondary to rupture of mucinous tumor with subsequent implantation of mucin secreting cells on peritoneum. We experienced a case of pseudomyxoma peritonei due to ruptured mucinous cystadenoma of ovary, borderline malignancy. This paper presents this case and a brief review of the literature.

급성 췌장염 치료 중 발생한 베르니케뇌병증 2예

안득수,이수택,최정기,이양덕,이치국,이성중 대한소화기학회 2001 대한소화기학회지 Vol.37 No.4

The local and systemic complications of acute pancreatitis are protean. The systemic complications include pulmonary, cardiovascular, hematologic, renal, metabolic, and central nervous system abnormalities. Wernicke's encephalopathy is developed due to diencephalic and mesencehalic dysfunction of central gray structures surrounding the third and fourth ventricles by thiamine deficiency. Patients who are in fasting state, receiving parenteral nutrition, recovering from gastrointestinal surgery, being fed after a period of starvation, undergoing hemodialysis, or suffering from advanced cancer, are particularly susceptible to Wernicke's encephalopathy. Here, we report two cases of Wernicke's encephalopathy complicated during the management of acute pancreatitis.

약물의 in vitro 투과 실험을 위한 사람의 비강점막상피세포 단층막의 일차배양

유진욱,김유선,이민기,노환중,이치호,김대덕 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.1

The primary culture of human nasal epithelial cell monolayer was performed on a Transwell. The effect of various factors on the tight junction formation was observed in order to develop an in vitro experimental system for nasal transport studies. Human nasal epithelial cells, collected from human normal inferior turbinates, were plated onto diverse inserts. After 4 days, media of the apical surface was removed for air-liquid interface (ALI) culture. Morphological characteristics was observed by transmission electron microscopy (TEM). A polyester membrane of 0.4 μm pore size was determined as the most effective insert based on the change in the transepithelial electric resistance (TEER) value as well as the ^14C-mannitol transport study. The ALI method was effective in developing the tight junction as observed in the further increase in the TEER value and reduction in the permeability coefficient (P_app) of ^14C-mannitol transport. Results of the transport study of a model drug, budesonide, showed that the primary culture system developed in this study could be further developed and applied for in vitro nasal transport studies.

내시경적 경접형동 접근법 후 발생하는 비부비동 합병증: 단일기관 연구

장효범,이재민,박다희,노환중,이치형,성순기,조규섭,문수진 대한이비인후과학회 부산,울산,경남 지부회 2022 임상이비인후과 Vol.33 No.4

Background and Objectives: The endoscopic transsphenoidal approach (TSA) is the standardized surgical approach to sella lesions providing a wider field and resulting in fewer neurosurgical complications. However, sinonasal complications are relatively less studied. This study aims to analyze sinonasal morbidities after endoscopic TSA performed by a single center. Materials and Methods: Among 154 patients who underwent endoscopic TSA from 2015 to 2022, 107 patients who were followed up for more than 3 months were included and retrospectively reviewed. Sinonasal complications including crust, discharge, septal perforation, synechia and polypoid sphenoid mucosa at postoperative 3 month were evaluated with olfactory function. The patients were subdivided into nasoseptal flap (NSF), non-NSF, 1st phase (initial 3 years, n=53) and 2nd phase (later 4 years, n=54) groups for further analysis. Results: There were 47 male (43.9%) with a mean age of 51.6 (range 15–83). The mean follow-up duration was 10.9 (range 3–46) months. Crust (28, 26.2%) was the most frequent morbidity followed by synechia (18, 16.8%), hyposmia (17, 15.9%), discharge (14, 13.1%), polypoid sphenoid mucosa and septal perforation (8, 7.5%). NSF was associated with crust formation and septal perforation (p<0.001). Olfactory function was relatively preserved at 3 month (p=0.065). Post- operative cerebrospinal fluid (CSF) leak decreased in the 2nd phase (4/54, 7.4%) compared to the 1st phase (12/53, 22.6%) (p<0.05). Conclusion: Crust was the most frequent sinonasal morbidity after endoscopic TSA followed by synechia. NSF was associated with crust and septal perforation. Post-op CSF leaks could be reduced after overcoming the learning curve of endoscopic TSA.