한국전쟁 직전 북한의 위협에 대한 미국 정책결정자들의 인식

이철순 원광대학교 채문연구소 2000 역사와 사회 Vol.25 No.-

This paper examines American decision makers' perception of North Korea's threat immediately before the Korean War. According to Raymond Cohen, threat perception is composed of not only the stage of observation but also that of evaluation of threat. American decision makers could observe North Korea's threat enough, but they did not evaluate it seriously. They did not think it threatening. The reasons for that are as follows: First, American decision makers placed very low value on Korea in terms of military strategy, assuming that a future war with U.S.S.R would be general. That is why they were not sensitive to the report which dealt with North Korea's military threat. Second, they thought the possibility that the communist would attack Korea was very slight. Third, the excess of intelligence made them unsusceptible to North Korea's threat. Fourth, they were very worried about Syngman Rhee's intention to march North. They suspected that South Korea exaggerated North Korea's threat. Fifth, their evaluation of South Korean forces' ability to deter North Korea's attack was very ambiguous, though they recognized the superiority of military capacity of North Korea to that of South Korea. Sixth, they thought that North Korea would continue to use the tactic of penetration rather than the full-scale overt military attack. Seventh, the specialist on intelligence submitted the report on North Korea's military capacity, not its intention to attack South Korea. That is why American decision makers underestimated the North Korea's threat. American decision makers did not deter North Korean military attack not because they intended to provoke it, but because they did not interpret North Korea's military threat serious.

한국 공연예술 시설의 재정자립도 기준에 따른 조직 운영 양태분석

이철순 한국문화예술경영학회 2009 한국문화예술경영학회 학술대회 Vol.2009 No.1

Aripiprazole과 Haloperidol의 섬망 치료에 대한 효과 비교

이철순,임광민,한규희,김봉조 대한정신약물학회 2007 대한정신약물학회지 Vol.18 No.4

Objectives: Delirium is defined as an alteration in mental status characterized by brief disturbances in consciousness and attention, cognition, and perception that tend to fluctuate during the course of the day. Traditionally, haloperidol has been used to treat agitation as it may occur in delirium. However, atypical antipsychotics are increasingly used to treat delirium itself. A comparative study was undertaken to compare the clinical efficacy of haloperidol and aripiprazole for the treatment of delirium. Methods: Forty patients (20 patients assigned to haloperidol and 20 to aripiprazole) diagnosed with delirium by DSM IV-TR were recruited and randomly assigned to receive a flexible-dose regimen of haloperidol or aripiprazole over 7 days. The severity of delirium was assessed by using the Delirium Rating Scale–Revised-98 scores (DRS–R-98). Results: DRS–R-98 severity scores for each group decreased significantly over the study period (P < 0.01), but no statistically significant difference was detected between the two groups (P = 0.607). Conclusion: These data show no statistically significant difference in efficacy between haloperidol and aripiprazole in the treatment of delirium. Since haloperidol has great potential for causing EPS, aripiprazole, a medication with known low side effects, may be an effective alternative agent in the treatment of delirium. 섬망(delirium)은 의식의 장애와 주의력 저하뿐만 아니라 정동, 사고, 언어 등 인지 기능 전반의 장애와 정신병적 증상을 유발하는 정신 질환으로, 높은 유병율과 사망률로 인해 신속한 치료가 필요하다. 섬망의 치료로는 섬망의 주요 신경 전달 물질인 도파민을 억제하는 정형 항정신병 약물이 섬망 치료에 사용되어 왔으나 최근 비정형 항정신병 약물을 도입하려는 시도가 증가 하고 있다. 이에 본 연구는 전통적 치료제인 haloperidol과 비정형 항정신병 약물 중 하나인 aripiprazole의 섬망 치료 효과를 비교 연구하였다. 전체 40명 중 20명의 환자가 halo-peridol을 복용하였고, 20명의 환자가 aripiprazole을 복용하였다. 섬망의 심각도 및 호전 정도를 평가하기 위해서는 섬망 평가 척도개정판(Delirium Rating scale-Revi -sed-98, 이하 DRS-R-98)을 사용하였다. 본 연구는 섬망 치료에 있어서 aripiprazole과 haloperidol의 효과를 비교한 최초 연구로서, 연구 결과 haloperidol 군과 ari-piprazole 군 모두에서 유의하게 DRS-R-98의 심각도 점수가 감소하였지만 두 군 간에 DRS-R-98 심각도 점수 변화의 차이는 없었다. 따라서 본 연구 연구 결과는 섬망 치료에 있어서 aripiprazole이 haloperidol의 대체 약물이 될 수 있다는 가능성을 시사하는 것으로, 향후 섬망 환자의 치료에 있어서 임상적인 치료 지침을 새롭게 마련할 뿐만 아니라 정신과 자문 의뢰에 대한 진료의 질을 높이는데 기여할 수 있을 것이다.

청년 이승만의 국제정치관에 관한 연구 : 이상주의와 현실주의를 중심으로

이철순 한국지방정치학회 2022 한국지방정치학회보 Vol.12 No.1

Based on the specific reference to his newspaper articles published during his youth and his book, The Spirit of Independence, this paper seeks to explore whether the young Syngman Rhee at the time had an idealistic or realistic political perspective. He had a deep understanding of the main concepts of political realism such as anarchical nature of international politics and balance of power. However, the solution he suggested for then weak Yi Dynasty, such as the obedience of international law, the expansion of trade and open door policy was based on political idealism and was a strong one. He was more of a political idealist rather than a political realist in this sense. 이 논문은 이승만의 신문 논설과 그의 저작 『독립정신』 분석을 통해 그가 청년기에 이상주의와 현실주의 국제정치관 중 어디에 더 경도되었는지를 살펴보고자 했다. 이승만은 현실주의의 주요 개념인 국제정치의 무정부성, 세력균형 등을 잘 파악하고 있었다. 그러나 그가 당시 약소국이었던 대한제국에 내린 처방은 만국공법 준수, 통상의 확대, 문호개방정책의 실시와 같은 이상주의적인 것이었고 그것은 강력한 것이었다. 이런 면에서 이승만은 현실주의보다 이상주의에 더 경도되었다고 할 수 있다.

국악과 문화정책에 관한 몇가지 단상

이철순 민족음악학회 1995 음악과 민족 Vol.10 No.-

리스페리돈으로 유발된 체중 증가와 혈장 Ghrelin 농도의 상관 관계

이철순,김은희,박철수,김봉조 대한정신약물학회 2006 대한정신약물학회지 Vol.17 No.5

Objectives: Although enhanced appetite and weight gain are potential side effects of treatment with antipsychotic agents, the mechanism is poorly understood. Ghrelin is a newly discovered appetite-stimulating peptide that has a role in the regulation of feeding behavior. Ghrelin is synthesized principally in the stomach, and the concentration of circulating ghrelin is negatively correlated with body fat mass. This study was designed to investigate the correlation between plasma ghrelin levels and weight gain following risperidone treatment. Method: Thirty-six schizophrenia patients, according to DSM-IV criteria, who did not take any antipsychotic medications for the previous two months were recruited. All the patients were administrated with 2-6 mg/day of risperidone for 8 weeks. Plasma ghrelin levels, weight and height of these subjects were measured before and after 2, 4, 6, 8 weeks administration of risperidone. The concentrations of growth hormone, insulin, glucose and lipid metabolic parameters were measured before and after 8 weeks administration of risperidone. Results: The body mass index (BMI) and body weight increased, whereas the plasma level of total and active ghrelin decreased significantly after risperidone treatment (p<0.01). The changes in total and active ghrelin level were negatively correlated with the changes in BMI and body weight (p<0.01). Conclusion: Plasma ghrelin concentration decreased, whereas body weight and body mass index (BMI) increased in schizophrenia patients treated with risperidone. Our results suggest that ghrelin is negatively correlated with risperidone induced weight gain. 목 적 :체중 증가는 항정신병약물 투여로 나타나는 주요 부작용이지만 아직까지 알려진 기전은 없다. Ghrelin은 섭식 행동의 조절 역할을 하는 것으로 알려진 신경펩타이드로써 혈장 ghrelin 농도는 체지방량과 역 상관 관계를 가진다. 본 연구는 정신분열병 환자를 대상으로 8주간 리스페리돈을 투여 후 체중과 ghrelin 농도의 변화를 조사하여 ghrelin 농도와 항정신병약물로 인한 체중 증가의 상관 관계를 보고자 하였다. 방 법 :DSM-Ⅳ 진단 기준을 만족하는 정신분열병 환자 중 최근 2개월 동안 항정신병약물을 복용하지 않고 연구에 서면 동의한 36명이 연구에 포함되었다. 대상 환자들은 2~6 mg/day의 리스페리돈을 투여하였으며 약물 투여 전과 투여 후 2, 4, 6, 8주에 체중, 신장, 혈장 ghre-lin 농도를 측정하였다. 혈당, 총 콜레스테롤, 고밀도 지단백-콜레스테롤, 저밀도 지단백-콜레스테롤, 중성 지방, 인슐린, 성장 호르몬 농도는 약물 투여 전과 투여 후 8주째에 측정하였다. 결 과 :리스페리돈 투여로 체중 및 체질량지수는 유의한 증가를 보였으며(p<0.01), ghrelin 농도는 통계적으로 유의한 감소를 보였다(p<0.01). 약물 투여 전과 투여 8주 후의 체중 변화는 활성 ghrelin 농도 변화와 유의한 역 상관 관계를 보였지만(p<0.01), 전체 ghrelin 농도 변화와는 통계적으로 유의한 상관 관계를 보이지 않았다(p> 0.05). 약물 투여 8주 후 체질량지수 변화는 전체 및 활성 ghrelin 농도 변화와 유의한 역 상관 관계를 보였다(p< 0.05).

나노섬유를 이용한 반도체형 가스센서

이철순,이종흔 한국세라믹학회 2013 세라미스트 Vol.16 No.1

Proteomic Analysis of Rat Brains Following Exposure to Electroconvulsive Therapy

이철순,강기련,이지영,박철수,한규희,손진욱,김봉조 대한의학회 2009 Journal of Korean medical science Vol.24 No.1

Electroconvulsive therapy (ECT) is one of the most effective treatments used in psychiatry to date. The mechanisms of ECT action, however, are the least understood and still unclear. As a tool to elucidate the mechanisms of action of ECT, we employed proteomic analysis based on the identification of differentially expressed proteins after exposure to repeated ECT in rat brains. The expression of proteins was visualized by silver stain after two-dimensional gel electrophoresis. Of 24 differentially expressed protein spots (p<0.05 by Student t-test), six different proteins from 7 spots were identified by matrix-assisted laser desorption/ionization time-of flight (MALDI-TOF)/mass spectrometry. Among the identified proteins, there were five dominantly expressed proteins in the ECT-treated rat brain tissues (p<0.05); S100 protein beta chain, 14-3-3 protein zeta/delta, similar to ubiquitin-like 1 (sentrin) activating enzyme subunit 1, suppressor of G2 allele of SKP1 homolog, and phosphatidylinositol transfer protein alpha. The expression of only one protein, ACY1 protein, was repressed (p<0.05). These findings likely serve for a better understanding of mechanisms involved in the therapeutic effects of ECT.

전문 인력 활동 및 지위 보장을 위한 국공립 공연장 법인화의 한국형 대안

이철순 한국문화예술경영학회 2010 한국문화예술경영학회 학술대회 Vol.2010 No.1

우사 김규식의 삶과 정치활동

이철순 (사)한국인물사연구회 2011 한국인물사연구 Vol.16 No.-

Most of previous works about Kyu-sik Kim's political activities describes him as idealist who puts emphasis on political ideas and motives. Thorough investigation of his political activities from 1945 to 1948, however, leads us to find new fact that he has also some aspects of political realist who sets high value on political outcomes and interests. The reasons for that are as follows:First, when he was selected "president" by the American Military Government officials in 1946, he showed his desire for power. Second, when the UN general assembly decided to hold an election in Korean Peninsular in 1947, he welcomed it. He changed his position, however, when the UN little assembly decided to hold election in Southern part of Korean Peninsular in 1948. He thought that his participation in the election was disadvantageous to his political interests because he had very weak organizational power in South Korea. Third, even though he initiated "north-south joint conference idea", he was very negative and pessimistic about that conference after he saw the translation of Pyongyang draft constitution of Korean People's Republic which meant the actual establishment of North Korean separate regime. Fourth, American Military Government officials thought that while on surface Kyu-sik Kim cried out for "unification of Korea", in reality basic cause of his proposal for north-south conference and acceptance of Pyongyang's invitation was realization that he had no real following. They had also information that Kyu-sik Kim had secretly(because he was openly boycotted election) told his friends to nominate candidates and campaign for them in the first general election in 1948. In all consideration of these facts, we find that Kyu-sik Kim has also some aspects of political realist as well as political idealist.