PCR 기법을 이용한 인공감염토양 및 감염동물 장기로 부터 Bacillus anthracis의 검출

이지연,유한상,김종염,Lee, Ji-youn,Yoo, Han-sang,Kim, Jong-yeom 대한수의학회 1998 大韓獸醫學會誌 Vol.38 No.3

Anthrax caused by Bacillus anthracis is one of the most important zoonotic diseases in the worldwide. To control and prevent the disease effectively, several methods such as development of a fast and specific diagnostic method and vaccine, education etc, have been carried out. However, it still has a problem in the control and prevention. To control, the most important method is the prevention of direct or indirect contact of the causative agent with susceptible host. Therefore, we developed a fast and specific detection method, polymerase chain reaction, of B anthracis from soil and infected animals because the organism could survive long time in the environment including soil due to formation of spore. With the method, virulence genes of B anthracis were successfully amplified from experimentally infected soil and mice. Up to $4.2{\times}10$ of the organisms per gram could be detected with the PCR method from experimentally infected soil. These results suggested that this PCR method could be effectively used not only to detect B anthracis in soil and infected animal but also to provide the information to prevent the disease.

교통사고 관련 외상후 스트레스 장애 환자에서 신체적 외상의 정도와 외상후 스트레스 장애 증상의 심각도 사이의 관계

이지연,나철,조주연,Lee, Ji-Youn,Na, Chul,Cho, Ju-Yeon 한국정신신체의학회 1998 정신신체의학 Vol.6 No.1

Objective: This study was designed to evaluate the etiological factors of the PTSD(post traumatic stress disorder) by examining the relationship between severity of physical trauma and subsequent the severity of PTSD symptom in traffic accident related PTSD patients. Method: Subjects were 21 psychiatric inpatients with history of traffic accident related PTSD(DSM-IV criteria), the purpose of evaluation of mental disability and no evidence of organic brain leisons. The severity of physical trauma was assessed by McBride number of nonpsychiatric department and the presence / absence of loss of conciousness. The severity of PTSD symptom was assessed by Hovens' self rating inventory for PTSD. And then we evaluated the correlation between these two factors. And we also evaluated relationship between severity of PTSD symtom and clinical variables. Results : There were no significant relationship between McBride number of nonpsychiatric department severity and symptomatic severity(r= 0.17, p<0.05), the presence / absence of loss of conciousness and symptomatic severity(p>0.05). And significant relationship between symptomatic severity and clinical varibles such as sex, education level, marital status(p<0.05). Conclusions : These data did not support data of previous studies that traumatic severity was correlated with symptom severity but, suggested that other variables affecting the severity of PTSD symptom is more important indirectly. And that the 'trauma' in PTSD is psychological meaning rather than physical meaning is also suggested.

한약 투여후 발생한 급성담즙정체성(약제유인성)간염 치험 1례

이지연,김관식,정용준,김형균,이언정,최우정,한상칠,오명진,오로사,양재훈,Lee, Ji-Youn,Kim, Kwan-Sik,Jeong, Yong-Jun,Kim, Hyung-Kuen,Lee, Eon-Jeong,Choi, Woo-Jung,Han, Sang-Chil,O, Moung-Jin,O, Ro-Sa,Yang, Jae-Hoon 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2

In western medicine, there are some reports about herbal medicine induced hepatitis, but in oriental medicine, there are few reports about that. We experienced one case of drug acute cholestatic-hepatitis in the treatment of oriental medicine for HNP. We treated the patient with acupuncture, physical therapy and herb medicine. The patient's symptoms improved after two weeks of treatment. In the course of treatment, the patient intermittently complained of general weakness, nausea, yellowish urin, dyspepsia, and abdominal discomfort. We recognized that total bilirubin(7.2mg/dl), direct bilirubin(5.5mg/dl), serum transaminase(AST 360U/L, ALT 354U/L), alkaline phosphatase(16.6 K/A), urobilinogen(++) and bilirubin(++) were elevated. We diagnosed drug induced hepatitis. We stopped giving herb medicine and began giving Saeng gan gunbi-tang and Injin-oryung-san. Saeng gan gunbi-tang and Injin-oryung-san have been used to treat hepatic disease and have been known to have beneficial effects. After 3weeks on medication, the clinical symptoms and liver function improved. So, we report this case to bring more attention to the safety and toxicity of herbal medicine.

영 디자이너(young designer)의 스타트 업(start-up)에 관한보고

이지연(Lee, Ji Youn),나건(Nah, Ken) 한국디지털디자인협의회 2015 디지털디자인학연구 Vol.15 No.1

산업혁명이후 기계를 이용한 대량생산에 의해 대다수의 대중들도 물질의 풍요를 누릴 수 있게 되었다. 그러나 그들은 산업기반에서 점차 정보를 바탕으로 한 사회로 발전되어 가면서 제품 구매와 사용에 대해 기능의 만족을 넘어선 개인취향과 문화에 대한 요구를 시작했다. 교육과 정보를 통해 다양한 욕구를 갖게 된 현대의 소비자들이 타인과 차별화된 자신만의 개성을 표현하기 위해 노력을 해왔다. 이러한 요구에 디자이너들의 디자인 행위에 기능과 형태뿐만 아니라 새로운 콘셉트와 비전을 제시하기 위해 섬세한 소비자 분석 과정의 선행이 요구되고 있다. 이에 부합하기 위해서 디자이너는 고품격화 된 차별적인 디자인을 할 수 있는 지속적인 창의성의 개발하고 다품종 소량 생산으로 다양하게 상업화할 수 있는 여건을 갖춰야 함을 본 조사를 통해 이해할 수 있다. 현재 기존의 제조방식에서 벗어나 다양한 형태적 접근과 소량의 제품 생산법인 디지털 제조가 가능한 시대가 되어, 위에서 언급한 바와 같이 다양해진 소비자들의 요구를 충족시킬 수 있으며, 디자이너가 디자인부터 적절한 비용으로 디자이너의 역량이 충분히 발휘된 좋은 품질의 제품을 제조, 제품 프로모션까지를 이루어 낼 수 있는 독립적인 존재로 거듭날 수 있는 가능성을 볼 수 있다. 디자이너는 디지털 제조를 통해 자신의 비즈니스를 스타트 업(start-up)하므로 써 대량생산의 단점인 획일화된 제품으로부터 차별화될 수 있는 최선의 방법으로 소비자에게 한발 앞서 다가갈 수 있게 되었다. 동시에 독립적인 존재가 된 디자이너는 기업과 대등한 위치에 서서 자신들이 개발한 제품을 선보이므로 써 새로운 방식의 비즈니스를 영위해 나가면서, 어떠한 방법으로 생산자, 소비자, 디자이너 관계에서 디자이너의 전문성을 지킬 수 있는가에 대한 방법을 사례를 통해 알아본다. 또한 가정용 3d printer의 보급으로 소비자들 제품의 완성품을 구입하는 대신 온라인상에서 모델링 데이터를 변형시켜서 출력이 가능하게 되면서, 생산이 가능한 소비자로 인해 디자이너가 위협을 받는 것이 아니라, 이러한 배경에 소비자의 세심한 욕구를 만족하게 할 수 있는 디지털 제조 기술과 자유로운 사고를 바탕으로 한 창의력 있는 영 디자이너의 전문성이 더욱 더 요구됨을 알 수 있다. Since the Industrial Revolution mass production by machine has enabled majority people to enjoy abundance of products. However, as the society develops to one based on knowledge, the more education and information are approachable to the public the more people demand designs based on their own tastes and cultures, beyond convenience of technicality in products. In such a society educated consumers have more desire to express their own identities on products. Therefore, it is essential that designers develop new concepts in design and analyze consumers’ delicate tastes. This study shows that in demands for unique and high quality design designers in these days are required to develop their ability to refresh creativity ceaselessly and even to find how to commercialize their products in various ways. Especially in these days the digital fabrication method allows the entire process of production to be controlled by designers, from design, production and product management to advertisement. In this way designers work closer to consumers, with satisfying their particular tastes and nowadays they are also create a new way of professionalism, independent of manufacturers’. In this research by examples we try to see how to develop young designers’ professionalism through start-up among consumers and manufacturers.

장애학생과 일반학생의 구강건강상태 조사연구

이지연 ( Ji Youn Lee ),김창희 ( Chang Hee Kim ) 한국치위생과학회 2002 치위생과학회지 Vol.2 No.2

서울 화양동 주거지역의 도시조직과 상업화에 따른 건축물의 변화

이지연(Lee, Ji-Youn),김성홍(Kim, Sung-Hong) 대한건축학회 2013 대한건축학회논문집 Vol.29 No.1

The paper examines the urban fabric and architecture of Hwayang-dong in Seoul, a typical residential area developed by Land Readjustment (LR) Project in the late 1960s. LR was the major urban land development tool to make the residential areas outside the city center of Seoul from the 1960s to the 1980s. About 40% of Seoul’s urbanized areas were formed by LR. The paper analyzed the changes in streets, blocks, plots, and buildings at Hwayang-dong from the 1960s to the 2000s. The studied area was filled with one-story single-family detached houses as initially planned by LR from 1967 to 1977. During 1978 and 1987 the existing houses were partially modified and vertically expanded. Between 1988 and 1997 most houses were demolished and medium-scale multi-family houses or mixed use buildings were built under the pressure of commercialization. The period between 1998 and 2007 was the last phase that the area was transformed into the commercialized area with the implementation of District Unit Plan 2000. The paper classified 75 buildings at the studied area into six types; Vertical Addition of Single Family House (R-1), Vertical Addition and Transformed into Commercial Use (RC-1), Rebuilt as Single Family House and Transformed into Commercial Use (RC-2), Rebuilt as Multi-Family House (M-1), Rebuilt as Residential and Commercial Complex (RC-3), Rebuilt as Commercial Building (C-1). Through these phases over the 40 years the Hwayang-dong area has been transformed from the residential area into commercialized area.

태양전지를 위한 새로운 표면 패시베이션 (passivation) 박막의 특성 연구

이지연(Lee Ji Youn),이수홍(Lee Soo Hong) 한국태양에너지학회 2004 한국태양에너지학회 학술대회논문집 Vol.- No.-

1인 가구 증가에 따른 주거형태의 변화에 관한 연구

이지연 ( Lee Ji-youn ),김현진 ( Kim Hyun-jin ) 한국지역사회발전학회(구 한국지역사회개발학회) 2019 地域社會開發硏究 Vol.44 No.2

I studied on the preference of the housing environment of one person household in the quickly-increasing, housing options and the level of im-portance and provide the observation of property market and the basic data necessary in building a proper marketing strategy. First, 88.8% of households live in family. As tenure type, 62.2% of households own their houses and 29.7% of them live in leased house. As dwelling type, 59.4% of households live in apartments, 64.3% of households live in 3 room housing. Secondly, the result of analysis on the type of one person household housing and the level of preference by the form appeared as the following. In the survey of the intention about the independence in future, 37.4% replied in the cases of the intention of independence, currently independent living marking 29.4%, the case of the inttention of independence, marked 33.2% in the survey. Thirdly, in the survey of the level of preference to one person household, the level of importance of natural environment marked 4.06 points, the highest points, and in the next order the condition of location marked 4.05 points, the highest. They evaluated the high level of importance in the economic condition (M=3.92), interior structure and facility (M=3.66), and evaluated the comparatively low level of importance in the social environment (M=3.50). In selecting a house hereby when pollution became serious and the desire for the quality of living got strong, it was shown that natural environment and the condition of location acted as the biggest factor.

디자인 중심 혁신을 위한 창의성 발현 방법에 관한 연구

이지연(Lee, Ji Youn),나건(Nah, Ken) 한국디자인리서치학회 2019 한국디자인리서치 Vol.4 No.1

본 연구는 디자인 중심 혁신을 위한 디자이너의 창의성 발현을 실행중심의 방법론 위주로 고찰하는 것을 목표로 하였다. 존재하지 않았던 신제품과 다기능 제품 개발에서 효과적이고 순발력이 있는 디자이너의 창의성 발현 방법으로 사용자 중심의 실행 위주의 아이디어 발현법이 적합하다고 판단했기 때문이다. 이 연구는 혁신의 정의와 방식, 디자인 중심 혁신 그리고 창의성 발현에 대해 이론적인 배경을 조사하고, 5년 이내의 디자인 경력을 가진 40명의 디자이너를 대상으로 인터뷰를 진행하여 혁신, 창의성, 디자인 중심 혁신과 제품의 연관성 및 적용 방법을 알아보고 사례를 통해 근거를 마련하였다. 그 결과 디자이너가 생각하는 혁신은 패러다임, 생활 및 가능성의 새로움과 사용자의 경험을 위한 것이며 구체적인 형태나 기술에 국한되는 것이 아니라 생활 전반에 걸친 광범위한 업그레이드의 의미를 가지고 있음을 도출하였으며 사례연구를 통해 검증하였다. 본 연구는 디자이너의 디자인 중심 혁신과 창의성 발현은 실행중심의 방법론을 통해 이루어짐과 4차 산업혁명시대가 요구하는 혁신적 디자이너 양성이 가능함을 제시하는데 의의를 두었다. This study has its purpose in improving of a designer’s creativity for innovating the core of design by focusing on implementing-centered methodology. It is because the study has decided that methodology, which can develop ideas mainly through the user-centered tests, is appropriate as an effective & nimble method that can improve a designer’s creativity in developing new products & multi-functional products. This study has investigated the theoretical background of the definition and method of innovation, design-driven innovation, improving of creativity, and implementing-centered methodology, interviews with 40 designers who had up to 5 years’ experience in design, examined the connection between innovation, creativity, & design-driven innovation and products as well as various applications of implementing-centered methodology, and created the basis with actual cases. As a result, the study has found that innovation in the designer’s mind is for novelty in paradigm, living, & possibility as well as user experience, & has analyzed it as a wide-ranging upgrade of life as a whole instead of being restricted to specific form or technology. In this study, it was suggested that the design-driven innovation and creativity of designers can be improved through the implementing-centered methodology & based on this, it is suggested that innovative designers required by the 4th Industrial Revolution era can be trained.

문헌을 통해 본 전통 화장(化粧)의 용어고찰: 조선왕조실록을 중심으로, 고찰논문

이지연 ( Ji Youn Lee ),조우현 ( Woo Hyun Cho ) 한국미용학회 2020 한국미용학회지 Vol.26 No.1

In order to examine terms for the traditional make-up, this study arranged terms found in the Annals of the Joseon Dynasty recorded in the era of Joseon. The terms representing the traditional make-up can be divided into those with specific or comprehensive meanings, and the former can be again sub-divided into those depending on cosmetic forms or instruments. A preliminary study suggested that terms with specific meanings could be divided by cosmetic forms: Damjang(淡粧), Nongjang(濃粧), Yeomjang(艶粧), Ungjang(凝粧) and Yayong(冶容), and by cosmetic instruments: Bundae(粉黛) and Jibun(脂粉), while those with comprehensive meanings included Danjang(丹粧), Seongjang(盛粧) and Jangsik(粧飾), and there was Jangreom(粧奩) as a term for the traditional make-up instrument. Additional terms include Jeongjang meaning the application of powder and the drawing of eyebrows) and Jangso meaning make-up, as those with specific meanings, by cosmetic forms, while there were others by cosmetic instruments, such as Hongbun referring to rouge and powder, Miyeosak meaning the refinement of eyebrows, and Jajang, a term for the traditional cosmetic instrument.