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        시멘트를 사용한 Failed Total Hip Replacements에서의 금속 파편(Metallic Debris) 및 롤리에틸렌 파련(Polyethylene Debris)의 크기에 관한 연구

        이중명,Eduardo a. Salvati,Foster Betts,Edward F. DiCarlo,Stephen B. Doty,Peter G. Bullough (Joong Myung Lee) 대한고관절학회 1991 Hip and Pelvis Vol.3 No.2

        Reports of different failure rates with total hip replacements depending on the metal from which the parts were manufactured have prompted us to measure the size of metallic and polyethylene particulate debris present in the periarticular tissues around failed cemented total hip prostheses. Two methods of specimen preparation were used: An isolations method, in which the tissue was remove leaving the metallic debris and a non-isolation method consisting of routine histologic preparation for light microscopy. For each methods, we used the femoral components from ten cases each of titanium alloy, cobalt-chrome alloy, stainless steel. Particles were measured on a computer-assisted image analyzer. In all cases the mean size of metallic particulate debris with the isolation method was 0.8-1.0microns in short dimension and 1.5-1.8microns in long dimension. From the nonisolation method, the mean size was significantly smaller at 0.3-0.4 microns in short dimension and 0.6-0.7 microns in long dimension. Howerver, when the same technique was used, the sizes of metallic particulate debris did not differ. The mean size of polyethylene debris was 2-4microns in short dimerision, 8-3microns in long dimension, and was larger in tissues retrieved from titanium alloy failures than in tissues from cobaltchrome and stainless steel implants. This study suggests that factors other than the size of metallic debris (e.g. constituents of the alloy, amount, and celerity of generation of ddbris) may be more important for the failure of total hip replacement.

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