http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
비구조성 해면골 이식과 무두 압박나사 고정술을 이용한 주상골 요부 불유합의 치료
이준구,홍인태,김 욱,김준현,한수홍 대한수부외과학회 2016 대한수부외과학회지 Vol.21 No.3
Purpose: The authors performed an autologous cancellous bone graft from the iliac crest and headless compression screw fixation for the treatment of Mack- Lichtman type II scaphoid waist nonunion. The purpose of this study was to determine whether this procedure was effective in achieving bony union and restoration of alignment. Methods: We retrospectively reviewed medical records and radiographs of 30 patients who underwent a cancellous bone graft and headless compression screw fixation for scaphoid waist nonunion. There 28 men and 2 women with a mean age of 32.8 year-old (range, 21–63 year-old). The mean time to surgery from initial injury was 10 months (range, 3–25 months) and the average followup duration was 37.5 months (range, 15–52 months). The authors analyzed bony union, lateral intrascaphoid angle (LISA), scapholunate angle (SLA), radiolunate angle (RLA), and scaphoid length in radiographs and evaluated the modified Mayo wrist score (MMWS) as a functional outcome. Results: Bony union was achieved in all cases. In lateral plain X-ray, preoperative anatomic alignment including LISA, SLA, RLA, and scaphoid length was recovered at immediate postoperative measurement. Those alignment restoration was likely to maintain in final follow-up in despite of statistical difference. The wrist motion and the MMWS improved significantly at the last follow-up. Conclusion: A non-structural autologous cancellous bone graft from the iliac crest and headless screw fixation provided reliable results and can be one of the effective treatment options for patients with symptomatic Mack-Lichtman type II nonunion in the middle one-third of the scaphoid. 목적: Mack-Lichtman type II의 주상골 요부 불유합의 치료로 장골능에서 채취한 자가 해면골 이식술과 무두 압박 나사 고정술을 통한 골유합 및 정렬(alignment)의 회복에 미치는 임상적인 의의를 고찰하고자 한다. 방법: 방사선 사진과 의무 기록을 통한 후향적 연구로 총 30명(남 28명, 여 2명)의 환자가 포함되었다. 평균 나이 32.8세(범위, 21-63세), 수상 후 수술 시까지 평균 10개월(범위, 3-25개월), 평균 추시 37.5개월(범위, 15-52개월)이었다. 골유합 유무, 측부 주상골 내각(lateral intrascaphoid angle), 주상월상 각(scapholunate angle), 요월상 각(radiolunate angle), 주상골 길이(scaphoid length)를 측정하였고, 기능적 척도로 modified Mayo wrist score (MMWS)를 평가하였다. 결과: 전례에서 골유합이 이루었다. 측면 방사선 사진상 통계학적 차이는 있었으나 측부 주상골 내각, 주월상 각, 요월상 각 및 주상골 길이 모두 수술 전에 비해 수술 직후 해부학적 정렬의 호전을 보였으며, 통계적 차이는 있지만 수술 직후 회복한 해부학적 정렬은 최종 추시까지 유지되는 경향을 보였다. 전반적으로 임상적 평가에서 손목 관절 운동 및MMWS도 최종 추시 시 호전된 소견을 보였다. 결론: Mack-Lichtman type II의 주상골 요부 불유합의 치료로 장능골에서 채취한 자가 해면골 이식술 및 무두 압박 나사 고정술은 골유합 및 정렬의 회복에 좋은 결과를 보였으며, 효과적인 수술 방법으로 적용할 수 있을 것으로 생각된다.
이준구,서정혁,윤해정 한국응용생명화학회 2019 Applied Biological Chemistry (Appl Biol Chem) Vol.62 No.5
Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic and genotoxic chemicals naturally derived from food during heat processing. Edible oil is one of the most frequently contaminated foods. Many researches were recently conducted to determine the contents of PAHs and to assess their risks, but there have been no studies characterising risks of PAHs by calculating Margin of Exposure (MOE) of total PAHs instead of toxic equivalency factors (TEFs) concept in Korea. To analyze the 4 PAHs including benz(a)anthracene (BaA), chrysene (CHR), benzo(b)fluoranthene (BbF), and benzo(a)pyrene (BaP) simultaneously, gas chromatography with mass spectrometry was optimized. Total 303 edible oils were investigated and contaminated by 4 PAHs at ND–12.91 ng g−1. The MOEs were estimated by PAHs contents, daily consumption, and were over 10,000. The risk of PAHs of edible oils in Korea was of low concern. Furthermore, the MOEs of the estimated equivalent BaP calculated by TEFs of other 3 PAHs were higher than those of mixed PAHs, which would be overestimated.
Effects of food processing methods on migration of heavy metals to food
이준구,황정윤,이혜은,김태훈,최장덕,강길진 한국응용생명화학회 2019 Applied Biological Chemistry (Appl Biol Chem) Vol.62 No.6
Heavy metals including Lead (Pb), Cadmium (Cd), Arsenic (As) and Aluminium (Al) were analysed in oilseeds, noodles, tea leaves and their processed or cooked products to study the effects of food processing methods on migration of heavy metals. The heavy metals were determined with ICP-MS and ICP-OES following microwave-assisted acid digestion. Heavy metals in oilseeds, noodles and teas were reduced by extracting oils, boiling noodles, and infusing teas. And the transfer of heavy metals into boiling water and infusion tea was increased as the boiling and infusion time is increased. Heavy metals in foods are water soluble and heavy metals in foods would be decreased when foods are processed or cooked with water. Furthermore, it is needed to determine the migration rates in other cooked foods and assess the risk of heavy metals with concentrations calculated by the migration rates.