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전신마취하에서 시행된 악안면 골절 환자의 수술 전 후 혈당치 변화에 관한 연구
이주환,이동근 원광대학교 치의학연구소 1995 圓光齒醫學 Vol.5 No.1
Blood glucose levels are affected with changes of general condition, anesthetic agent, premedication, preoperative anxiety and stress. They are possible to cause hypoglycemia or hyperglycemia by secreting some kinds of hormones. Blood glucose levels were measured in patients who were fractured on facial bones. These patients received general anesthesia with halothane-N_2O-O_2 in Group Ⅰ and enflurane-N_2O-O_2 in Group Ⅱ . We injected pancuronium (0.1㎎/㎏) and succinylcholine (1㎎/㎏) as muscle relaxants in both groups. Blood glucose levels were measured for each time : 60 minutes before induction, pre-induction, pre-extubation and 30 minutes after extubation. The following results were obtained. 1) Perioperative blood glucose levels were significantly changed in both groups (p<0.05). 2) Compared with sex differences, the changes of perioperative blood glucose levels were highest in Group I female . 3) In age distribution, the changes of perioperative blood glucose levels were highest in Enflurane group of 30s' age (p<0.05). 4) In body weight distribution, the changes of perioperative blood glucose levels were highest in Halothane group of 40s' kgs. 5) In operation time, in Halothane group, blood glucose levels of the group in operation time over 90 minutes were significantly highier than within 60 minutes (p<0.05), but not significantly change in Enflurane group. We can suggest that surgery and general anesthesia regardless of agents could be stressful enough to cause elevation of blood sugar level but it did not seem to cause clinically significant hyperglycemia with above results.
Gender Differences Among Korean Patients With Coronary Spasm
이주환,이현상,배명환,권용섭,이장훈,류현민,박용휘,양동헌,박헌식,조용근,채성철,전재은,박의현 대한심장학회 2009 Korean Circulation Journal Vol.39 No.10
Background and Objectives: The gender differences among Korean patients with coronary spasm have not been defined. We thus determined the gender differences among Korean patients with coronary spasm. Subjects and Methods: Patients with chest pain and/or syncope who were admitted to Kyungpook National University Hospital between January 2001 and August 2008 were included. Provocation of coronary vasospasm with intracoronary ergonovine maleate was performed when baseline coronary angiography showed no significant stenosis or there was a strong clinical suspicion of coronary spasm. The clinical characteristics were analyzed from 104 consecutive patients (56±9 years of age; 21 females) who were diagnosed with coronary spasm. Results: Female patients were younger (52±7 vs. 57±10 years, p=0.046) with lower rates of smoking and alcohol consumption histories than male patients (19% vs. 65%, p<0.001; and 43% vs. 89%, p<0.001, respectively). The other clinical characteristics were not significantly different, except for the triglyceride levels. Conclusion: The majority of patients with coronary spasm were males who were smokers and alcohol consumers. The female patients had lower rates of smoking and alcohol consumption, and they were younger than the male patients. Further studies are needed to investigate the relevance of gender differences in the pathogenesis of coronary spasm. Background and Objectives: The gender differences among Korean patients with coronary spasm have not been defined. We thus determined the gender differences among Korean patients with coronary spasm. Subjects and Methods: Patients with chest pain and/or syncope who were admitted to Kyungpook National University Hospital between January 2001 and August 2008 were included. Provocation of coronary vasospasm with intracoronary ergonovine maleate was performed when baseline coronary angiography showed no significant stenosis or there was a strong clinical suspicion of coronary spasm. The clinical characteristics were analyzed from 104 consecutive patients (56±9 years of age; 21 females) who were diagnosed with coronary spasm. Results: Female patients were younger (52±7 vs. 57±10 years, p=0.046) with lower rates of smoking and alcohol consumption histories than male patients (19% vs. 65%, p<0.001; and 43% vs. 89%, p<0.001, respectively). The other clinical characteristics were not significantly different, except for the triglyceride levels. Conclusion: The majority of patients with coronary spasm were males who were smokers and alcohol consumers. The female patients had lower rates of smoking and alcohol consumption, and they were younger than the male patients. Further studies are needed to investigate the relevance of gender differences in the pathogenesis of coronary spasm.