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이주명,조현성,Choi Ki Hong,Hong David,박택규,Yang Jeong Hoon,송영빈,Choi Jin-Ho,Choi Seung-Hyuk,정진옥,이종영,Choi Young Jin,Chae Jei-Keon,허승호,Bae Jang-Whan,Oh Ju-Hyeon,전국진,Kim Hyun-Joong,조병렬,Shin Doosup,Lee Seung Hun 대한의학회 2023 Journal of Korean medical science Vol.38 No.5
Background: The risk of device thrombosis and device-oriented clinical outcomes with bioresorbable vascular scaffold (BVS) was reported to be significantly higher than with contemporary drug-eluting stents (DESs). However, optimal device implantation may improve clinical outcomes in patients receiving BVS. The current study evaluated mid-term safety and efficacy of Absorb BVS with meticulous device optimization under intravascular imaging guidance. Methods: The SMART-REWARD and PERSPECTIVE-PCI registries in Korea prospectively enrolled 390 patients with BVS and 675 patients with DES, respectively. The primary endpoint was target vessel failure (TVF) at 2 years and the secondary major endpoint was patientoriented composite outcome (POCO) at 2 years. Results: Patient-level pooled analysis evaluated 1,003 patients (377 patients with BVS and 626 patients with DES). Mean scaffold diameter per lesion was 3.24 ± 0.30 mm in BVS group. Most BVSs were implanted with pre-dilatation (90.9%), intravascular imaging guidance (74.9%), and post-dilatation (73.1%) at proximal to mid segment (81.9%) in target vessel. Patients treated with BVS showed comparable risks of 2-year TVF (2.9% vs. 3.7%, adjusted hazard ratio [HR], 1.283, 95% confidence interval [CI], 0.487–3.378, P = 0.615) and 2-year POCO (4.5% vs. 5.9%, adjusted HR, 1.413, 95% CI, 0.663–3.012, P = 0.370) than those with DES. The rate of 2-year definite or probable device thrombosis (0.3% vs. 0.5%, P = 0.424) was also similar. The sensitivity analyses consistently showed comparable risk of TVF and POCO between the 2 groups. Conclusion: With meticulous device optimization under imaging guidance and avoidance of implantation in small vessels, BVS showed comparable risks of 2-year TVF and device thrombosis with DES.
랫드에서 hyaluronic acid에 의한 유착 방지 효과에 관한 연구
이종훈,이주명,윤영민,강태영,우호춘,강윤호,김남중,김희석,이경갑,정종태,Lee, Jong hoon,Lee, Joo Myoung,Yun, Young min,Kang, Tae young,Woo, Ho choon,Kang, Yoon ho,Kim, Nam joong,Kim, Hee seok,Lee, Kyoung kap,Cheong, Jongtae 대한수의학회 2004 大韓獸醫學會誌 Vol.44 No.4
This study was conducted to investigate the effect of hyaluronic acid (HA) on prevention of abdominal adhesions depending on various concentrations thereof by inducing an abrasion experimentally in the cecum of rats. Each group was consisted of 10 rats, and 40 rats were divided into 4 groups comprising the saline treatment group, HA 0.4% treated group, 0.6% treated group, and 0.8% treated group. And abrasion was caused in the cecum by using dry gauze and thereby, adhesion was induced. On 7 days after the operation, adhesions of each region were evaluated into the range of 0-4. Significant difference was found in the adhesion score between the control group and each experimental group (P<0.05). Also, HA 0.4% treatment group showed the lowest adhesion score (P<0.05). In the light of the above results, HA 0.4% solution was more effective on prevention of adhesion than HA 0.6% and 0.8% solution.
이종현 ( Jong Hyun Lee ),김지원 ( Ji Won Kim ),이주명 ( Joo Myung Lee ),박현태 ( Hyun Tae Park ),송재윤 ( Jae Yun Song ),이규완 ( Kyu Wan Lee ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.11
목적: 골반 방선균증은 드문 질환으로, 자궁내 피임장치와 관련되는 혐기성 그람양성균인 Actinomyces israelii에 의해 발생하는 만성 육아종성 화농성 농양을 형성하며, 수술 전에 정확한 진단하는 것이 어렵다. 골반 방선균증을 자주 골반내 부인과적 악성종양과 혼동되어 잘못된 진단을 하게 하거나 불필요하게 지나친 치료를 하게 된다. 저자들은 골반 방선균증 8예를 경험하였고 이를 통해 골반 방선균증의 치료에 대해 알아보고자 하였다. 방법: 저자들은 1999년 1월부터 2007년 1월까지 골반 방선균증으로 진단받고 고려대학교의료원 안암병원 산부인과를 방문한 8예의 의무기록을 후향적으로 조사하였다. 결과: 환자들의 평균연령은 45.2세였으며 주 증상은 하복부동통이었고, 다른 증상으로는 질출혈, 질분비물과다, 생리통, 오한을 동반한 열감 등이 있었다. 모든 예에서 5-20년간 자궁내 피임장치를 사용한 과거력이 있었다. 3예는 자궁내막 조직검사, 자궁경부 조직검사와 경험적으로 수술전에 진단되었다. 5예에서 수술 후 진단되어 항생제 치료를 시행하였고 2예는 오직 항생만으로 치료하였으며, 나머지 1예는 항생제 치료 후 수술을 시행하였다. 모든 환자는 완치되었다. 결론: 방선균증의 치료에 있어서 가장 중요한 점은 장, 방광, 골반장기의 손상과 같은 합병증을 줄이기 위해 수술 전에 진단을 내리는 것이다. 수술 후 진단되었다면 수술 후 고용량 항생제 치료가 필요하다. Objective: Pelvic actinomycosis is a rare disease, which make chronic granulomatous suppurative pelvic abscess caused by an anaerobic Gram positive organism Actinomyces israelii usually associated with intra-uterine devices, and difficult to diagnose exactly before operation. Pelvic actinomycosis is frequently confused with gynecologic malignancy, leading to misdiagnosis and overtreatment. We experienced 8 cases of pelvic actinomycosis and provide the advice for treatment of pelvic actinomycosis. Methods: We reviewed retrospectively the medical chart of 8 cases which have visited to Department of Obstetrics and Gynecology, College of Medicine, Anam Hospital, Korea University for pelvic actinomycosis from January 1999 to January 2007. Results: The mean age of patients was 45.2 years old. Main symptoms were abdominal pain, vaginal bleeding, vaginal discharge, dysmenorrhea and fever with chilling. All cases have used the intrauterine devices for 5-20 years. 3 cases were diagnosed preoperatively by endometrial biopsy, punch biopsy, or empirically, and the others suspected to tuboovarian abscess or malignancy, and then their diagnoses were conformed by operation. 5 cases were treated by operation following antibiotics therapy, and 2 cases by antibiotics without operation, and 1 case by antibiotics therapy following operation. All cases were completely cured. Conclusion: In the treatment of pelvic actinomycosis, most important point is making the diagnosis before operation for decreasing complication such as bowel, bladder, and other pelvic organ injury. Inevitably, if the diagnosis was established by operation, postoperative high-dose antibiotic therapy was needed for several months.
이병서(Byoung Seo Lee),이주명(Ju Myoung Lee),이준식(Joon Sik Lee) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.6
A computer program for unstructured grid system is developed, which can describe unsteady fluid flow and heat transfer by the fractional step method and SIMPLE method. The governing equations are discretised based upon the finite concept method, a kind of finite volume method. The validity of the program is established in comparison with the benchmark solutions, which shows good agreements with both two methods. The present study reports difference in computational time depending on two different methods and flow types.
디자인사고의 의미 비교 : 허버트 사이몬과 IDEO의 디자인사고를 중심으로
이정열(Lee Jung-yeol),이주명(Rhi Joo-myung) 한국디자인학회 2010 한국디자인학회 학술발표대회 논문집 Vol.2010 No.10
In the past, design was considered only a styling on a product's shape or form. But now design has effect on the whole Life, in areas such as politics, economy, business, environment, etc. This design power expanded the design field and changed the design concept as well so that it rapidly raised more concerns for 'design thinking.' The purpose of this study is to clear the definition of 'design thinking' which is the core of the change. For the more detailed research, to understand the meaning of Herbert Simon's 'design thinking,' the background and some of the historical concerns that have emerged with 'design thinking' were researched(based on Nigel Cross's research). Also compared of what the two design thinkers(Herbert Simon, IDEO) think about design thinking. It shows design thinking's common & difference features. In short, define the 'design thinking' clearly after synthesize design thinking's common features through two cases since 20C. In addition, Clear up the 'design thinking' should be more useful to develop variety fields like a society, politic, economy, and the environment more the better. Finally, I suggest some critical points of 'design thinking' today.