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      • KCI등재후보

        감초 지표성분 분석법 확립 및 liquiritigenin의 함량 증대를 위한 감초의 수치에 관한 연구

        이종록,조미정,박상미,김상찬,박숙자,Lee, Jong-Rok,Jo, Mi-Jeong,Park, Sang-Mi,Kim, Sang-Chan,Park, Sook-Jahr 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.1

        Objective : Licorice has been used for treating digestive disorder and also recommended as a detoxification agent. Liquiritigenin, a component of licorice, has been reported to have various biological activities. In this study, we aimed to establish the analytical method for liquiritigenin content in licorice and the processing method for the enhancement of liquiritigenin content in licorice. Methods : Processing was accomplished by roasting licorice at $250^{\circ}C$ for indicated time periods (5-20 min). Analysis of liquiritigrnin from roasted licorice was conducted using UPLC(Ultra Performance Liquid Chromatography). Results : We established UPLC method for the analysis of liquiritigenin using water : acetonitrile gradient as mobile phase. Furthermore, we standardized the processing condition of licorice to enhance liquiritigenin content using UPLC method. Processing of licorice was accomplished by roasting at $250^{\circ}C$ for indicated time periods (5-20 min) and by pretreating with 50% of acetic acid or 30% ethanol for 24 h. By roasting licorice, the liquiritigenin contents in the licorice were increased. The best roasting time of licorice was 6 min, while roasting for the time above 8 min resulted in diminishing liquiritigenin contents. Moreover, pretreatment with 50% of acetic acid or 30% ethanol picked up liquiritigenin contents in roasted licorice. Conclusion : The adequate processing condition of licorice for the enhancement of liquiritigenin contents was obtained by pretreating licorice with 50% of acetic acid or 30% ethanol for 24 h and then by roasting at $250^{\circ}C$ for 6 min.

      • KCI등재

        현호색(玄胡索)과 초초현호색(醋炒玄胡索)의 여드름균에 대한 항균효과 비교

        이종록,박숙자,김영우,조일제,변성희,김상찬,Lee, Jong-Rok,Park, Sook-Jahr,Kim, Young-Woo,Cho, Il-Je,Byun, Sung-Hui,Kim, Sang-Chan 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.3

        Objectives : Corydalis tuber has been used for promoting blood circulation and for relieving pain in Oriental medicine. In the present study, we focused on the antimicrobial activity of Corydalis tuber and compared its antimicrobial activity with the processed Corydalis tuber. Methods : Processing of Corydalis tuber was accomplished by immersing in 5% of acetic acid for 12 h and then by roasting at $250^{\circ}C$ for indicated time periods(0-30 min). Minimum inhibitory concentration(MIC) and the zone of growth inhibition were determined against Propionibacterium acnes(P. acnes). Results : The methanolic extracts of Corydalis tuber showed potent antimicrobial effect(MIC 62.5 ${\mu}g/ml$). Its alkaloidal component, dehydrocorydaline, also exhibited antibacterial activity(MIC 25.0 ${\mu}g/ml$). After processing of Corydalis tuber, its inhibitory effect on the growth of P. acnes was significantly enhanced compared with that of unprocessed Corydalis tuber. Furthermore, elevated content of dehydrocorydaline was found in the processed than the unprocessed Corydalis tuber. However, the different roasting minutes effected on antimicrobial activity. The best roasting time of Corydalis tuber was 10 min, while roasting for the time above 15 min resulted in diminishing antimicrobial activity. Thus, it was concluded that the standardized processing condition of Corydalis tuber should be established to obtain enhanced antimicrobial(P. acnes) activity. Conclusion : For antimicrobial effect against P. acnes, the best processing condition of Corydalis tuber is immersing in 5% of acetic acid for 12 h and by roasting at $250^{\circ}C$ for 10 min.

      • 18세기 경주김씨(慶州金氏) 학주공파(鶴洲公派)의 대두와 기호학계에서의 위상

        이종록 ( Lee Jong-rok ) 한국계보연구회 2021 한국계보연구 Vol.11 No.-

        이 글은 서산 大橋[한다리]에서 세거했던 경주김씨 학주공파의 부상과 이를 가능하게 했던 動因을 遡及하여 분석한 것이다. 이들은 경주김씨 내에서 대안군파, 태사공파, 좌랑공파, 장단공파를 이어 학주공파로 분파되었다. 이들을 기록한 족보는 태사공파의 후손을 기록한 1685년(숙종 11)의 乙丑譜와 1784년(정조 8)의 甲辰譜가 있다. 족보 편수의 본래적 목적인 世系의 정비에 을축보가 김자수-김세필로 이어지는 사림 표방을 강조하고자 한 것이라면, 갑진보는 왕실의 일원임을 드러내고자 한 것이었다. 경주김씨 태사공파의 족보 간행을 둘러싼 수보 목적의 변화는 가문 내 중심축의 변화가 선행한 것이었고 동시에 정순왕후의 왕비 간택을 계기로 촉발된 학주공파의 대두가 존재했다. 하지만 단순히 왕후의 등장이 곧 그러한 변화를 가능케한 것은 아니었다. 당시 정순왕후의 至親들은 정치적으로 南黨-僻派을 조직하고 학문적으로는 湖論의 주요한 역할을 담당하였다. 남당이 자립할 수 있었던 까닭은 정순왕후의 후원 외에도 호론의 학문적 조력이 있었기에 가능한 것이었고, 여기에서 金漢祿의 역할이 두드러진다. 김한록은 호락논쟁이 격화되는 시기에 호론의 종장 韓元震에게 수학하였다. 김한록은 한원진에게 호론의 학문적 정체성을 물려받았고, 점차 호론의 중심적 역할을 담당하는 위치로 나아갔다. 하지만 호론은 주요 학자들의 사후 학통의 전수를 지속하지 못하였고, 김한록이 사후 八字凶言으로 충역 시비에 휘말리면서 벽파에 속하던 경주김씨들이 연좌되었다. 이는 벽파와 호론이 역사적 흐름에서 단절된 사건이기도 하였다. 수면 아래로 가라앉았던 호론이 역사 속에 재등장한 것은 일제의 침략이 가시화되는 근대전환기에 이르러서였다. 1895~1896년 홍주에서는 홍주의병이라는 반개화·반침략 반일투쟁이 일어났는데, 이때 의병의 이념적 기반이 호론에 근거한 것이었다. 이때 의병을 주도한 金福漢, 金商悳, 李偰 등은 모두 호론을 계승했다는 의식을 담지하고 있었는데 학통에 있어서 호론의 적전으로 김한록을 지목하였다. 이는 내포지역을 중심으로 형성되었던 김한록의 호론 내의 위상이 비로소 추인된 것이라 할 수 있다. This article analyzes the emergence of of Kim Hong-wook of Gyeongju Kim Clan, who lived in Daegyo, Seosan, and the key motivation that made it possible. They were divided into Hakjugong-pa following the Daeangun-pa, Taesagong-pa, Jwaranggong-pa, and Jangdangongpa within Gyeongju Kim Clan. Eulchukbo in 1685 (the 11th year of King Sukjong's reign), which recorded the descendants of Taesagong-pa, and Gapjinbo in 1784 (the 8th year of King Jeongjo's reign) are the genealogical records of Gyeongju Kim Clan. If Eulchukbo had an intention to emphasize the advocacy of Sarim leading to Kim Ja-su and Kim Se-pil in terms of the original purpose of organizing genealogy, the purpose of organizing Gapjinbo was to reveal that it was a part of the royal family. The change in the purpose of organization surrounding the publication of genealogical records by Gyeongju Kim Clan’s Taesagong-pa was due to the change in the central force in the family, and simultaneously, the rise of Hakjugong-pa, triggered by selection of a spouse for the Royal family-the royal family’s selection Queen Jeongsun-had a great influence. However, simply the appearance of the Queen did not make such a change possible. At that time, Queen Jeongsun's close relatives politically organized Namdang-Byeokpa and academically, played a major role in Horon. The reason why the Namdang was able to stand on its own feet was because of the academic assistance of Horon in addition to the support of Queen Jeongsun, where Kim Han-rok's role stands out. Kim Han-rok studied with Han Won-jin, the instructor of Horon, at a time when the Horak debate was intensifying. Kim Han-rok inherited the academic identity of Horon from Han Won-jin, and gradually moved to a position that plays a central role in Horon. However, Horon failed to continue the transfer of scholarship after the death of major scholars, and Gyeongju Kim Clan, who belonged to Byeokpa, was taken over as Kim Han-rok was embroiled in a dispute over the loyalty with the "Eight letters of curse[Palja Hyung-eon 八字凶言]" after his death. This was also an event in which Byeokpa and Horon were cut off from historical stream. Horon, which had subsided below the surface, reappeared in history when the Japanese invasion became visible. From 1895 to 1896, an anti-Japanese struggle broke out in Hongju under the banner of anti-enlightment and anti-invasion called the Hongju Righteous Army. Kim Bok-han, Kim Sang-deok, and Lee Seol, who led the righteous army, all had a sense of inheriting Horon, and they pointed out Kim Han-rok as the heir of Horon in terms of academic background. This can be said that Kim Han-rok's status within the horon was formed around the Naepo area, and that status was finally confirmed.

      • KCI등재
      • KCI등재
      • SCOPUSKCI등재

        습진성 입술염 환자에서 첩포검사 결과에 관한 임상적 연구

        이종록 ( Jong Rok Lee ),이혜영 ( Hye Young Lee ),백진옥 ( Jin Ok Baek ),노주영 ( Ju Young Roh ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.1

        Background: Cheilitis is a common problem, the cause of which is often obscure. Objective: We evaluated the frequency of allergic contact cheilitis and irritant contact cheilitis among 23 eczematous cheilitis patients via patch testing and assessment of past medical history. Methods: This study consisted of 23 patients with eczematous cheilitis who had visited the Department of Dermatology, two University Hospital in Incheon, between January 2005 and August 2006. Of the 23 patients, 20 were female, and the age range was 15 to 70 years. We analyzed the clinical characteristics (age, gender, duration, atopic or allergic disease, lip licking) of the patients. All patients were patch-tested with the Korean standard series, 9 patients with the Cosmetic series and 5 patients with as is test. We then analyzed the results of the patch tests and evaluated the relevance of any positive results. Results: Of the cases, 34.78% were identified as irritant contact dermatitis (ICD), and 30.43% as allergic contact dermatitis (ACD). Furthermore, of the 23 patients, 11 were positive to one or more antigen and 7 of these had a clinical relevance for positive antigen. The substances causing a positive reaction, triggering ACD were identified as medicaments applied to the lip, lipstick ingredients and toothpaste. Conclusion: The most common cause of cheilitis was irritation, frequently caused by lip licking. But, almost one third was caused by ACD. Patients with chronic eczematous cheilitis should be patch-tested to identify the materials causing ACD. (Korean J Dermatol 2007;45(1):9~13)

      • KCI등재

        An Analysis on the Contents of the Stele of Koguryŏ in Ji’an with Regard to Koguryŏ’s Reorganization of Sumyoje

        Jong-Rok Lee(이종록) 고려대학교 한국사연구소 2017 International Journal of Korean History Vol.22 No.2

        高句麗의 守墓制에 관해서는 지금까지 학계에 다양한 연구가 이루어져 왔으나, 수묘제의 운영과 그 구성원에 대해서는 여전히 해결되지 않은 여러 문제들에 대해 논란이 있다. 이러한 논란의 원인 중 하나는 廣開土王碑를 제외하면 관련 사료가 한정되어 있기 때문이었다. 그러나 2012년 集安高句麗碑의 발견으로 인해 수묘제에 대한 논의가 다시 활성화되는 동시에, 기존의 수묘제에 대한 해석에도 재고의 여지를 주게 되었다. 비록 집안고구려비의 建碑 연대 및 목적에 대해서는 견해가 엇갈리고 있으나, 기본적으로 이것이 당대의 수묘제와 깊은 관련이 있다는 것은 분명하다. 따라서 지금까지의 이 비에 관한 연구들은 수묘제에 관해 주로 논하는 경우가 대부분이며, 이에 따라 비의 발견 이후 짧은 기간 동안에 다양한 학설이 제시되어 왔다. 본고에서는 집안고구려비에 관한 기존의 논의를 검토하는 동시에, 이를 토대로 광개토왕비에서 전하는 수묘제 재정비의 배경에 대해 별도의 가능성을 제기해 보았다. 곧 비문의 守墓人 賣買 禁止 조항이 단지 수묘제에 한정된 문제가 아닌, 당대 고구려의 주민집단의 재편과 인력 부족을 극복하기 위한 정책의 일환이었다고 추정하였다. 이는 두 비문에서 공통적으로 언급하는 수묘인 매매가 守墓役에 한정된 관행이 아니라 고구려의 力役動員體制에서 전반적으로 나타나고 있던 현상이라는 가정으로부터 도출된 결론이다. 그리고 이 관행의 문제점을 인지한 고구려의 지배집단에 의해 집안고구려비와 같은 매매 금지령의 시행되었으며, 이는 4세기 무렵 前燕 및 百濟와의 전쟁으로 야기된 인력부족 현상을 극복하기 위한 노력의 일환이었다고 이해된다. Despite a considerable amount of research focused on Koguryŏ"s Sumyoje (守墓制), there are many unsolved issues regarding the characteristics of the custodians of the royal tombs because the Stele of King Kwanggaet’o has been the only source to examine the system. In this sense, the Stele of Koguryŏ in Ji’an (集安高 句麗碑; Chiban Koguryŏbi in Korean),” found in 2012, provides an opportunity to reinterpret the system, drawing scholarly attention to Koguryŏ"s Sumyoje again. Although the date and purpose of the stele is still amidst debate, historians generally agree that the purpose of the stele is related to the custodians for the royal tombs. Naturally, most of the recent articles on the newfound stele have addressed this system, broadening our perspective on Koguryŏ’s domestic administration. This paper, based on the interpretations and arguments of previous studies, argues that the Stele of Koguryŏ in Ji’an was a part of Koguryŏ’s general policy to reorganize their control over their inhabitants and overcome the shortage of manpower. Under the hypothesis that “selling and buying” the custodians and, ultimately, statute labors had been habitually practiced in Koguryŏ before this time, it is possible that the ruling class of Koguryŏ recognized the necessity to forbid this custom around the fourth century as the kingdom suffered a shortage of manpower especially after the continuous wars against the Yan dynasty and Paekche.

      • KCI등재

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