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      • 인지행동재활치료가 정신분열병 환자들의 인지 기능에 미치는 영향

        이원혜(Won-Hye Lee),황태연(Tae-Yeon Hwang),이우경(Woo-Kyung Lee) 대한사회정신의학회 2001 사회정신의학 Vol.6 No.2

        목 적: 본 연구는 만성 정신분열병 환자들을 대상으로 실시한 인지행동재활치료(CBRT)의 효과를 검증하고자 하였다. 연구방법: 만성 정신분열병으로 진단 받아 입원 중인 환자 12명을 대상으로 매주 1회(매회 50분간)씩 18주 동안 지남력, 주의집중력 훈련, 기억력 훈련, 변별력 및 조직화 훈련 등 4단계로 구성된 인지행동재활치료(CBRT)를 실시하였다. 대조군으로는 동일한 기간동안 일반적인 정신사회재활치료를 실시한 집단(n=9명)과, 일반적인 입원 치료만을 받은 집단(n=9명)을 두었다. 세 집단 모두 치료 전과 치료 후 신경심리 검사를 실시하여 그 변화를 비교하였다. 치료 전과 치료 후 인지 기능의 변화를 알아보기 위해 세 집단 모두, KWIS(Korean Wechsler Adult Intelligence Scale)의 WARD7 단축형, DS-CPT(Degraded Stimulus Continuous Performance Test), SPAN(SPAN of Apprehension Program), Word Fluency Test, Word Memory Test를 실시하였다. 결 과: 세 집단의 치료 전, 후 인지 기능 변화의 주효과 및 상호작용 효과를 살펴보기 위한 MANOVA 분석 결과, KWIS의 숫자, 상식, 토막짜기, 빠진곳 찾기에서 집단간 주효과(p<.05)가 발견되었는데, CBRT 집단이 다른 두 집단에 비해 토막짜기, 빠진곳 찾기의 수행이 유의하게 상승하였다. 또한, 산수와 SPAN에서는 치료 전, 후의 상호작용 효과도 관찰되었는데(p<.05), CBRT 집단은 치료 후 SPAN의 12matix에서 유의한 상승을 보인 반면, 일반적인 입원 치료만 받은 집단은 수행 수준이 오히려 감소하였다. 집단 내 변화를 알아보기 위해 세 집단 각각에 대해 paired-t test를 시행한 결과, CBRT 집단은 KWIS의 전체 지능, 동작성지능, 토막짜기, 빠진곳 찾기와 SPAN의 12matrix, 언어적 유창성에서 치료 후 수행이 유의하게 증가하였으나(p<.05). 정신사회재활치료 집단은 KWIS의 동작성 지능에서만 유의한 변화가 있었으며(p<.05), 일반적인 입원 치료만 받은 집단은 신경심리 검사의 어떤 변인에 대해서도 유의한 변화가 나타나지 않았다. 결 론: 만성 정신분열병 환자들을 대상으로 한 CBRT는 전반적인 인지 기능 향상에 효과적이었으며, 특히 시각적 기민성과 변별 능력, 지각적 분석 및 통합 능력, 적극적이고 융통성 있는 사고 활동에 긍정적인 영향을 미치면서 행동적 수준의 변화로 이어지고 있음을 시사한다. 이러한 신경심리 검사에서의 수행 향상이 치료 후에도 지속될 수 있는지에 대한 추후 연구(follow-up)가 필요할 것이다. 또한, 기초인지 기능의 향상이 일상생활의 적응이나 대인 관계 기술, 직업 수행 등 전반적인 기능의 호전으로 일반화 될 수 있을 지에 대해서도 후속 연구가 필요할 것이다. Objectives:This study was designed to investigate the outcomes of the Cognitive Behavioral Rehabilitation Therapy (CBRT) for chronic schizophrenic patients. Methods:The subjects were 30 chronic chronic schizophrenic inpatients. CBRT group(N=12) was given orientation training, visual discrimination and organization training, attention and concetration training, and memory function training. Compared groups were given psychosocial rehabilitation(N=9) and general inpatient care(N=9). Korean Wechsler Intelligence Scale(KWIS), Continuous Performance Test(CPT), Span of Apprehension(SPAN), Verbal memory test and Verbal fluency test were performed before and after the interventions. Results:CBRT group were significantly improved in full IQ, performance IQ, picture complete, block design, Span 12matrix, verbal fluency. But psychosocial rehabilitation group was only improved in performance IQ and general inpatient group showed no significant effects in all outcomes variables. Conclusion:Our findings suggest that CBRT for chronic schizophrenic patient was effective on improving general cognitive function. Especially, it increased psychomotor activity and entailed improvement of visual alertness, vigilance, perceptual organization and mental flexibility. In the future studies, follow-up study of effectiveness must be performed and generalization of cognitive functional improvement from CBRT into other psychosocial functions should be reviewed.

      • KCI등재

        The Korean Version of the Barkley Deficits in Executive Functioning Scale: 성인 주의력결핍 과잉행동장애에서의 유효성 연구

        최지승,이원혜,안호원,김지혜,정유숙,이근희,이종일 대한신경정신의학회 2020 신경정신의학 Vol.59 No.2

        Objectives To identify the clinical utility of the Korean version of the Barkley Deficits in Executive Functioning Scale (K-BDEFS) assessing executive functioning. Methods The patient group included 144 adult attention-deficit/hyperactivity disorder (ADHD) patients visiting the Adult ADHD Outpatient Clinic of the National Center for Mental Health. Adult ADHD Self-Report Scale version 1.1, Mini International Neuropsychiatric Interview, and K-BDEFS were used. The control subjects were 144 age, sex, and education-matched general adults who participated in the study of the validity of the K-BDEFS in Samsung Medical Center. Results An analysis of the mean total K-BDEFS score, executive functioning symptom count, and ADHD-executive function (EF) index score revealed a significant difference between the adult ADHD and control group (p<0.05). Five subscales of the K-BDEFS, which assess the specific domains of the executive function, revealed a significant difference between the ADHD group and control group (p<0.05). The area under curve (AUC) of the K-BDEFS total score, the EF symptom count, and the ADHD-EF index were 0.943, 0.949, and 0.908, respectively, in the analysis using the receiver operating characteristic curve. All AUC values were over 0.90. Therefore, KBDEFS is a reliable and valid screening instrument for diagnosing adult ADHD. In an assessment of the sensitivity and specificity of the cutoff scores, a cutoff of 183.5 points for the K-BDEFS total score, 26.5 points for the EF symptom count, and 23.5 points for the ADHD-EF index showed a reliable sensitivity and specificity above 80%. Conclusion To the best of the authors’ knowledge, this is the first study to examine the predictive validity and clinical utility of K-BDEFS in adult ADHD. The results suggest that the K-BDEFS could be used as a valid and reliable tool for the diagnosis and clinical intervention of adult ADHD.

      • KCI등재

        주의력결핍 과잉행동장애 환아 평가시 지능검사의 유용성에 관한 예비연구

        민정원,이원혜,홍민하,반건호 대한소아청소년 정신의학회 2012 소아청소년정신의학 Vol.23 No.4

        Objectives:We analyzed the usefulness of intelligence test in assessing attention-deficit hyperactivity disorder (ADHD). Methods:The medical records of 312 patients with ADHD who visited the child psychiatry department in one university hospital in Seoul, Korea, were reviewed. Demographic data and scores on the Korean Wechsler Intelligence Scale for Children-III (K-WISC-III) and Korean-Conners’ Parent Rating Scale (K-CPRS) were analyzed. To assess the relationship with comorbidities, AD-HD subjects were classified as; externalizing disorders, internalizing disorders, tic disorders, and no comorbidities. Results:Verbal intelligence quotient (VIQ) was significantly higher than performance IQ (PIQ)(102.6±14.44, 99.2±14.48, p<.001). Using mean scatter method, subtest scores such as ‘information, similarities, digit span and coding’ were significantly lower than mean scores of sum of subtests of VIQ or PIQ (p<.05). Regarding comorbidities, children with externalizing disorders exhibited. Lower scores on ‘information and vocabulary’ than other groups (p=.008). Children with no comorbidities exhibited higher scores on ‘similarities and object assembly’ than children with externalizing/internalizing disorders (p=.001) and also on ‘comprehension’ than children with externalizing disorders (p=.006). For subtypes of ADHD, children with hyperactive-impulsive type had higher scores on ‘comprehension’ than children with inattentive and combined type (p=.004). Conclusion:These results suggested that intelligence test might provide useful information for assessing ADHD.

      • KCI등재

        의과대학생 및 의학전문대학원생의 공감 능력과 학제, 학년 그리고 성격의 연관성

        이병국,이원혜,박준헌,윤태영,반건호,백상빈 한국의학교육학회 2009 Korean journal of medical education Vol.21 No.2

        Purpose: This study investigated the relationship between empathy and medical education system, grades, and personality in medical college (MC) students and medical school (MS) students. Methods: One hundred fifty-five MC students and 137 MS students participated in this study, completing questionnaires on sociodemographic data, Jefferson Scale of Empathy, S-version, Korean edition (JSE-S-K), and Temperament and Character Inventory (TCI). Results: Reward Dependence (RD), Cooperativeness (C), and Self-directedness+ Cooperativeness (SC), which are subscales of the TCI, correlated significantly with JSE-S-K score. Third-year students had significantly higher scores on the JSE-S-K than first-year students. MS students had significantly higher scores on the JSE-S-K and the SC subscale of the TCI than MC students. However, there were no significant differences in empathy with regard to age, sex, motivation toward medical science, club activity, and applied specialty. Conclusion: These results suggest that empathy is associated with personality traits, such as RD, C, and SC, and medical education curriculum contributes incrementally to empathy for students. The difference in test scores for empathy between MC students and MS students might be due to differences in personality traits, such as SC.

      • KCI등재

        조현병 환자를 위한 마음이론 향상 재활 프로그램의 효과 검증

        김신향,이원혜,권정혜 한국임상심리학회 2013 Korean Journal of Clinical Psychology Vol.32 No.3

        People with schizophrenia show major deficits in social cognition, especially theory of mind (ToM). Social cognitive deficits are promising treatment targets for new interventions to improve functional outcome in schizophrenia. The purpose of this study was to examine the efficacy of a Social-Cognition Rehabilitation Program (SERP) focused on theory of mind. This program was modified from the original version, developed by Kwon (2003) and verified by Choi and Kwon (2006), especially for improvement of theory of mind. The SERP focused on theory of mind was composed of 16 sessions, including 14 sessions dealing with faux pas, hidden intentions and emotions and one session each for orientation and ending. The aim of the program was to help individuals with schizophrenia to enhance social cognition including theory of mind and ultimately to promote daily social skills and interpersonal ability. The SERP focused on theory of mind was compared with treatment as usual within a two group pre-post design in 52 people with schizophrenia in the community. Theory of mind, social cognition and functional outcome were assessed before and after the eight week training phase. Patients in the treatment group showed significant improvement theory of mind and social skill abilities after the program, but not in general social cognition and interpersonal abilities. Our findings suggested that theory of mind could be improved in people with schizophrenia by implementation of a social cognition enhancing rehabilitation program focused on theory of mind. Conduct of further study will be needed in order to determine whether enhanced theory of mind will have an effect on general social cognition.

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