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- 저자 : 이선열 ( Sun Yeul Lee ) (검색결과 3 건)
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부인과 복강경 수술 환자에서 Ramosetron의 투여 시기가 수술 후 오심과 구토에 미치는 영향
이선열 ( Sun Yeul Lee ),신용섭 ( Yong Sup Shin ),김정현 ( Jeong Hyun Kim ),최연희 ( Youn Hee Choi ),고영권 ( Young Kwon Ko ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.6
Background: Patients undergoing laparoscopic gynecological surgery have a remarkably high incidence of postoperative nausea and vomiting (PONV). The purpose of this study was to evaluate the effect of the timing of ramosetron administration on its antiemetic efficacy in patients undergoing laparoscopic gynecological surgery. Methods: One hundred and twenty patients undergoing laparoscopic gynecological surgery under general anesthesia were randomized to receive 0.3 mg of ramosetron intravenously either immediately after induction (group I, n=60) or at the completion of surgery (group II, n=60). Occurrences of nausea and vomiting, the need for rescue antiemetics and analgesics, pain score, as well as adverse events associated with study medications, were recorded for 48 hrs after the operation. Results: The incidence of postoperative nausea and vomiting in the I and II groups were 46.7%, 41.7% respectively. There was no significant difference between the groups in the incidences of PONV, the need for rescue antiemetics and analgesics, pain score and adverse events associated with study medications (P>0.05). Conclusions: The effect of ramosetron administered either immediately after induction or at the completion of surgery was similar to each other on its efficacy as a prophylactic antiemetic in patients undergoing laparoscopic gynecological surgery. (Korean J Anesthesiol 2009; 56: 663~8)
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Sevoflurane을 이용한 흡입마취유도 시 remifentanil을 이용하였을 때 적절한 sevoflurane의 농도
김정현 ( Jeong Hyun Kim ),윤희석 ( Hee Suk Yoon ),이선열 ( Sun Yeul Lee ),신용섭 ( Yong Sup Shin ),윤석화 ( Seok Hwa Yoon ),최연희 ( Youn Hee Choi ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.2
Background: Currently, sevoflurane and remifentanil are utilized frequently for the inhalation induction of anesthesia. However, there is currently an insufficient amount of clinical data regarding the inhalation induction of sevoflurane after the administration of remifentanil. Methods: 80 patients undergoing elective surgery were allocated randomly to four groups. Group A inhaled only sevoflurane at 8 vol%. Other groups were administered 3 ng/ml of remifentanil and inhaled sevoflurane at 8 vol% (group B) or 6 vol% (group C) or 4 vol% (group D). All groups also received 0.6 mg/kg of rocuronium. The blood pressure and heart rate were measured at pre-induction, and before and after tracheal intubation. After operation, the patients` levels of satisfaction with the inhalation induction were evaluated. Results: The time to loss of consciousness was substantially longer in group D than in the other groups, but no significant differences were noted among the groups in terms of satisfaction scores. The HR in groups B, C and D increased significantly after pre-intubation as compared to baseline in group A. The HR decreased significantly during induction as compared to group A. The MAP in groups B, C and D decreased significantly at 1 and 2 minutes after tracheal intubation as compared to group A. In group D only, we noted no significant differences in the MAP as compared to baseline at 1, 2 minutes after tracheal intubation. Conclusions: 4 vol% sevoflurane was a more appropriate concentration for the inhalation induction of anesthesia when coupled with 3 ng/ml of remifentanil. (Korean J Anesthesiol 2009;57:170∼5)
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완전정맥마취에 의한 수술 중 Hydroxyethyl Starch (130/0.4) 용액의 동시투여가 혈소판 기능에 미치는 영향
조호연 ( Ho Yeon Cho ),신용섭 ( Yong Sup Shin ),손수창 ( Soo Chang Son ),이선열 ( Sun Yeul Lee ),조완호 ( Wan Ho Cho ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.6
Background: Colloid solutions are used to treat hypovolemia and expanding plasma, but they may inhibit platelet function and reduce the level of coagulation factors during surgery. This study was conducted to compare the effects of hydroxyethyl starch (HES) on adenosine diphosphate (ADP)- and collagen-induced platelet aggregation in patients undergoing total intravenous anesthesia. Methods: Patients undergoing endoscopic sinus surgery under total intravenous anesthesia with propofol and remifentanil were divided into a group that underwent fluid management with only crystalloid solution (n=15) and a group that was managed with crystalloid solution that included 6% HES (130/0.4) (n=15). ADP-and collagen-induced platelet aggregation were measured 5 minutes before induction, after the first intraoperative hour, and one hour postoperatively. Results: Significantly diminished ADP- and collagen-induced aggregation values were observed intraoperatively when compared with the preoperative value in the patients that were managed with colloid solution that included HES. In addition, significantly diminished collagen-induced aggregation values were observed intraoperatively when compared with the preoperative value in the group that was managed with the solution that only contained the crystalloid. However, ADP -and collagen-induced platelet aggregation were recovered postoperatively in both groups. Conclusions: The results of this study indicated that fluid therapy with colloid solution that contained 6% HES (130/0.4) may diminish ADP-induced platelet aggregation intraoperatively in patients subjected to total intravenous anesthesia. (Korean Aens-En)
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