조기위암의 복강경 보조 원위부 위절제술과 개복술의 비교

이상일(Sang-Il Lee),윤유석(Yoo-Seok Yoon),최유신(Yoo-Shin Choi),김형호(Hyung-Ho Kim),한호성(Ho-Seong Han),양한광(Han-Kwang Yang) 대한외과학회 2005 Annals of Surgical Treatment and Research(ASRT) Vol.68 No.3

급성 폐동맥색전증과 성인성호흡곤란증후군에서 산소운반과 산소섭취의 상관관계

이상도 ( Lee Sang Do ),한성구 ( Han Seong Gu ),심영수 ( Sim Yeong Su ),김건열 ( Kim Geon Yeol ),한용철 ( Han Yong Cheol ) 대한내과학회 1993 대한내과학회지 Vol.44 No.4

연구배경 : 성인성 호흡곤란증후군에서 PEEP을 적용할 때 산소운반을 최대로 하려는 노력은 결국 조직에서의 산소섭취를 최대로 하기 위해서이며, 이는 조직의 산소섭취가 산소운반에 비례한다는 가정에 근거하나 이에 대해서는 아직 이견이 많다. 한편 성인성 호흡곤란증후군과는 호흡부전의 기전이 다른 급성 폐동맥색전증에서 산소운반과 산소섭취의 상관관계에 대해서는 아직 알려진 바 없다. 방법 : 성인성 호흡곤란증후군과 급성 폐동맥색전증에서 산수운반과 산소섭취의 상관관계를 밝히고자 한국산 잡견 14마리중 7마리에는 oleic acid를 정주해 성인성호흡곤란증후군을 유발하고 나머지 7마리에는 자가혈병을 이용해 급성 폐동맥색전증을 유발한 후 PEEP 수준을 변화시키며 환기 및 혈류역학의 제지표를 측정해 다음과 같은 결과를 얻었다. 결과 : 1) 산소운반과 산소섭취 : ARDS군은 12~28ml/min/kg 의 산소운반 범위에서 산소운반의 감소에 따른 산소섭취의 감소를 관찰할 수 있었고, 산소운반의 변화와 산소섭취의 변화사이에는 유의한 상관관계가 있었다(r=0.55, p<0.05). 산소추출률(oxygen extraction ratio)과 산소운반 사이에는 유의한 상관관계가 없었다. 급성 폐동맥색전증군에서 역시 7~29ml/min/kg의 산소운반 범위에서 산소운반의 감소에 따른 산소섭취의 감소를 관찰할 수 있었고, 산소운반의 변화와 산소섭취의 변화 사이에 유의한 상관관계가 있었다(r=0.57, p<0.05). 산소추추률과 산소운반 사이에는 유의한 상관관계가 없었다. 2) 혼합정맥혈 산소분압 : ARDS군에서 산소운반의 변화와 혼합정맥혈 산소분압의 변화 사이에는 유의한 상관관계가 있었고 (r=0.79, p<0.05), 혼합정맥혈 산소분압의 변화와 심박출량의 변화사이에도 유의한 상관관계가 있었다(r=0.75, p<0.05). 급성 폐동맥색전증군에서 역시 산소운반의 변화와 혼합정맥혈 산소분압의 변화 사이에는 유의한 상관관계가 있었고(r=0.83, p<0.05), 혼합정맥혈 산소분압의 변화와 심박출량의 변화사이에도 유의한 상관관계가 있었다(r=0.72, p<0.05). 결론 : 이상의 결과로 산소공급에 대한 조직에서 산소 섭취의 의존성은 성인성 호흡곤란증후군에 국한된 현상이 아니고 급성 폐동맥색전증에서도 관찰되며, 혼합정맥혈 산소분압은 이 두 질환에서 조직에의 산소공급의 변화를 예견할 수 있는 유용한 지표로 생각된다. Background: In adult repiratory distress syndrome(ARDS) the pathologi supply dependence of oxygen consumption, whoch provide the basis for `best PEEP`, is suggested, but which is still in controversy. And in acute pulmonary embolism little is known about the relationship betwen oxygen transport and oxygen consumption. Methods: To evaluate the relationship betwen oxygen transport and oxygen consumption in ARDS and acute pulmonary embolism, experimental ARDS was induced in 7 mongrel doges with oleic acid and acute pulmonary emblism in 7 dogs with autologous blood clot. Then hemodynamic and gas exchange parameters were measured with serial increment of PEEP. Results: In ARDS group, blow the oxygen transport of 28 ml/min/kg, the change of oxygen consumption was linearly related to the change of oxygen transport(r=0.55, p<0.05). Oxygen extraction ratio didn`t correlate with oxygen transport. In acute pulmonary embolism group, below the oxygen transpot of 29ml/min/kg, change of oxygen consumption was linearly relatred to change of oxygen transport(r=0.57, p<0.05). Oxygen extraction ratio didn`t correlate with oxygen transport. In ARDS group there was a significant correlation between the change of oxygen tension (r=0.79, p<0.05). In acute pulmonary embolism group there was a significant correlation between the change of oxygen transport and change of mixed venous oxygen tension (r=0.83, p<0.05). Conclusion: These data suggest that a linear relationship between oxygen consumption and oxygen transport is not unique to ARDS. Mixed venous oxygen tension seems to be sensitive predictor of oxygen transport in both ARDS and acute pulmonary embolism.

양형실태 분석을 통한 양형기준 개선방안 고찰

이상한(Lee, Sang-Han) 한국형사법학회 2013 刑事法硏究 Vol.25 No.2

After conducting studies and analyses for two years, from 2007 to 2009, in April 2009, the Sentencing Guidelines Commission formulated sentencing guidelines for the crimes of homicide, bribery, sexual assault, robbery, embezzlement/breach of trust, perjury, and false charges and enforced the application of these sentencing guidelines to the related crimes as of July 1, 2009. The present study is very important, as it examines the present state of concrete sentencing judgments, at a point when the sentencing guidelines have been in effect for approximately four years, and it evaluates whether the sentencing guidelines have been properly observed since their enforcement, and whether the observance of the sentencing guidelines ensures the expected predictability of jurisdiction. To that end, the present study, centering on the judgments on the crimes of embezzlement/breach of trust out of the crime groups subject to the sentencing guidelines currently in effect, analyzes the actual conditions of sentencing by examining all first trial judgments applied according to the sentencing guidelines between July 1, 2009 and December 31, 2010. The present study intends to seek measures for enforcing the sentencing guidelines more efficiently by examining whether the intent and objectives of the introduction of the system were properly implemented in 2009 and evaluating the results of the enforcement by conducting an extensive analysis. The analysis focuses primarily on three matters in the sentencing guidelines that are in need of improvement. First, the sentencing guidelines for the selection of types of penalties in cases where the statutory punishments include several types of punishments, particularly in cases where personality servitudes and pecuniary punishments coexist, are necessary, as well as those for pecuniary punishments. Second, for the sentencing guidelines to be effective, actual binding force should be given to the sentencing guidelines. Third, the writing of the reasons for sentencing in written judgments should be compulsory. Furthermore, the way of writing the reasons for sentencing in written judgments should be unified to enable the post hoc verification/improvement of the sentencing guidelines, thereby ensuring greater transparency and objectivity in sentencing.

지난 8년간의 구강악안면외과 입원환자에 대한 임상통계학적 분석

이상한(Sang Han Lee),김진수(Chin Soo Kim),장현중(Hyun Jung Jang),홍창수(Chang soo Honag),최강영(Kang Young Choi) 대한구강악안면외과학회 1995 대한구강악안면외과학회지 Vol.21 No.2

This study was done to analyze annual changes in hospital admission rates, coming rate at emergency room and demographic profiles of hospital care in Oral and Maxillofacial Surgery (OMS) and Kyungpook National University Hospital (KNUH) at the Taegu City and Kyungpook Province region 1986-1933. The result were as follows : 1. In annual changes of inpatient, increasing rate of inpatients from 1986 to 1933 were 12.9% (OMS), 10.8% (KNUH), male to female ratio was about 1.9 : 1(OMS), 1.2 : 1(KNUH). 2. There was more deviation of the month at early stage (1986-1989) and less deviation at the stage (1990-1993). 3. Most of inpatients at surgical parts (62.9% OMS, 76.1% KNUH) underwent operation under G.A.(95.8% OMS, 65.8% KNUH) 4. For the consultation, 108.3 cases were referred from OMS, and 287.4 cases were referred to OMS. 5. In annual changes of each department, total number of inpatient-days and discharged patient by 1993 were over the average values of each other at NEU, OB & GY, ENT, OMS. 6. In annual changes of patients at emergency room, increasing rate of coming patients were 12.5% (OMS), 5.6% (KNUH). Also average coming patients per day was incresed from 0.4 to 0.9 7. By assoryment of patients, component ratio of T.A. was largely decresed from 10.4% (1986-1989) to 5.3% (1990-1991) 8. There was ore patients in September (OMS, August-October at T.A.), and less in February (OMS, T.A). 9. Most of coming patients came from Taegu(53.2%) and Kyungpook province(43.7%)

Analysis of Anti-Allergic Activities by Extracts from Persimmon Sap-Stained Rayon and Cotton Fabrics

Sang-Han Lee(이상한) 한국생명과학회 2010 생명과학회지 Vol.20 No.5

알러지성 피부염은 현재 영유아 4인 중 1명이 발병할 정도로 심각한 질환으로 보고되어 있다. 본 연구는 청도 감물염색을 한 직물 2종(인견과 면)의 물 추출물이 알러지성 피부염 유도 동물모델에서 피부의 표피에 면역관련의 세포의 수를 감소시킴을 H&E 염색으로 확인하였으며, 알러지성 피부염에 직접 관련이 있는 분자표적인 CD4? cell의 분포를 비교하여 본 결과, 유의성 있게 항알러지성 피부염 활성을 보유하고 있는 것을 확인하였다. MMP-2와 MMP-9의 면역조직화학적 분석을 수행한 결과, 이들의 발현도 감소함으로 감물염색에 사용된 감의 유용성분 예를 들면 폴리페놀 성분 등이 알러지성 피부염의 억제활성에 관련이 있을 것으로 추정된다. Allergic dermatitis is one of the most prevalent diseases in young/juvenile children worldwide. In this research, extracts with persimmon sap-stained fabrics (rayon and cotton) exhibited an elevation in CD4? cell numbers. MMP-2 and MMP-9 expressions by Hematoxylin-Eosin staining and immunohistochemistry revealed that the expressions were decreased by addition of the extracts. The present results collectively suggest that the active ingredients of persimmon sap-stained fabrics play an important role in inhibition of DNFB-induced-atopic symptoms in vivo.

Free composite graft 을 이용한 우측 비익부 성형술 1 예

이상한(Sang Han Lee),이열희(Yeoul Hi Lee),변기정(Gi Jung Byun),김진수(Jin Soo Kim),이경우(Kyung Woo Lee) 대한악안면성형재건외과학회 1978 Maxillofacial Plastic Reconstructive Surgery Vol.1 No.1

We successfully corrected the alar defect, of nose with free composite graft from the ear. In relatively small defects of the alar region, it has been more recommendable than any other methods, such as pedicle skin grafts. It`s advantages are as follows; 1. It can be performed at one-stage procedure. 2. Its colour match is harmonious with recipient site. 3. Also, its texture is similar with recipient site. 4. Its outline is similar with ala nasi in marginal curve and thickness. But it can not be employed in a large defects of nose.

하악골에 발생한 법랑아세포종의 치험예

이상한(Sang Han Lee),변종수(Jong Soo Byun),옥윤경(Yun Kyung Ok),김석환(Suk Hwan Kim),김무중(Moo Jung Kim) 대한악안면성형재건외과학회 1982 Maxillofacial Plastic Reconstructive Surgery Vol.4 No.1

This is a case of Ameloblastoma occured in the right Mandibular body and angle region. We considered this tumor to be associated with tooth follicle or follicular cyst. Partial mandibulectomy and bone graft was performed for the removal of lesion and the reconstruction of resected Mandible and we obtained good functional and esthetic results.

과두절제술과 악교정술을 이용한 편측성 과두과증식의 치험례

이상한(Sang Han Lee),변종수(Jong Soo Byun),박주영(Joo Young Park),김상호(Sang Ho Kim),김진수(Jin Soo Kim) 대한악안면성형재건외과학회 1986 Maxillofacial Plastic Reconstructive Surgery Vol.8 No.1

We have treated 2 patients with unilateral condylar hyperplasia by condylectomy, vertical osteotomy and repositioning of maxilla. The results are as follows; 1. Case 1: Le Fort 1 osteotomy was taken for leveling of maxillary dentition. Rt. condylectomy and vertical osteotomy were taken for correction of facial asymmetry and malocclusion. 2. Case II; Posterior segmental osteotomy was taken for the leveling of maxillary dentition. Rt. Condylectomy, vertical osteotomy, chinplasty and bone graft on Lt. mandibular body were taken for correction of facial asymmetry and malocclusion. 3. In Case 1 and II; Condyles were replaced by use of silastic ulna head after condylectomy.

메탄 분류 화염에서의 연소 조건에 따른 NOx 배출 특성

이상한(Sang Han LEE),오창보(Chang Bo OH),이창언(Chang Eon LEE) 한국연소학회 2000 KOSCOSYMPOSIUM논문집 Vol.- No.-

하악후퇴수술후 연조직측모의 예측에 관한 연구

이상한(Sang Han Lee),권대근(Tae Geon Kwon),김진수(Chin Soo Kim),장현중(Hyon Jung Jang),최재갑(Jae Kap Choi) 대한구강악안면외과학회 1998 대한구강악안면외과학회지 Vol.24 No.1

본 교실에서 하악지시상골절단술을 시행한 악전돌증환자 15명(남자 5명, 여자 10명)을 대상으로 술전교정치료전(T1), 술직전(T2), 술직후(T3), 술후 6개월(T4), 술후 18개월(T5)의 변화를 관찰하여 경조직 변화에 따른 연조직의 변화와 그 관련성을 검토하여 다음과 같은 결론을 얻었다. 1. 하악의 연조직, 경조직은 술후 후방, 상방으로 위치하였다. 하악의 평균 이동량은 Pog에서 8.17mm였다. 술후 18개월의 관찰에서 하악의 경조직은 비록 적은 양의 변화가 있기는 하였으나 통계적으로 비교적 안정적인 위치를 유지하고 있었다. 2. 상, 하순연조직은 술후-장기관찰간에 변화가 있었으나 하악을 덮은 연조직은 술후-장기관찰간에 별다른 변화가 없었다. 상순 일부(Ls, stms)와 대부분의 하악연조직은 하악후퇴수술로 인하여 후, 상방으로 움직였으며 술후 6개월에서 술후 18개월간에는 비교적 안정적이었다. 18개월후 B 와 Pog 의 경조직 이동에 대한 연조직 이동비율은 84.7%, 74.7% 였다. 3. 하악후퇴수술후 하악연조직위치를 장기적으로 예측하는 것은 경조직을 예측하는 것보다 더 어려우며 유의성도 적었다. 이것은 술후 환자의 안모를 정확히 예측해내기는 어려을 뿐 아니라 통상 1 : 1 비율의 변화를 적용시키는 컴퓨터 안모예측 시스템을 이용할 때 주의를 요한다는 것 의미하는 것으로 보인다. We usually accept 1 : 1 ratio soft tissue change in mandibular set-back surgery. But we cannot sure whether we can use this ratio as a long term predictor after surgery. We investigated the change of hard tissue and its effects to soft tissue and examined the predictability of cephalometric analysis in short term and long term follow-up periods in mandibular set-back surgery. Subjects were 15 patients (5 male, 10 female) performed mandibular set-back procedure only by BSSRO with tigid fixation. Cephalometric data were obtained before orthodontic tretment, immediated before surgery and immediate after surgery, 6 months, and 18 months after surgery consecutively. Differences in soft and hard tissue changes among the time intervals were examined using analysis of vatiance (ANOVA) : the association between immediate surgical change in chin landmarks and subsequent short and long term soft and hard tissue changes were examined using linear regression analysis 1. Soft tissue mandibular structures were positioned posteriorly and superiorly after surgery. Average mandibular set-back were 8.17mm at Pog. The horizontal and vertical hard tissue mandibular changes were stable for 18 months after surgery. Although there was a small degree of change, soft tissue and hard tissue remain relatively stable after surgery and there was no clinically discernable changes between 6 months and 18 months post-operatively. 2. some part of upper lip (Ls & stms) and most part of mandibular soft tissue moves postero-superiorly mandibular set-back. The ratio of horizontal changes of hard tissue to soft tissue at Inf. labial sulcus(B ), Pogonion(Pog ) were 84.7%, 74.7% after 18 months, respectively. 3. Predictability of the soft tissue change is less certain than hard tissue and this predictability is decreased over time. These result suggests that we cannot predict the surgical outcomes exactly. It is recommendable that the oral surgeon should be careful in using the computerized surgical prediction software program as a predictor of long term soft tissue change.