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      • KCI등재

        Embossed Superhydrophobic Polymer Surfaces with Topological Variances

        이상언,임훈광,이승섭,최대근,이동진,홍성욱 한국고분자학회 2013 Macromolecular Research Vol.21 No.8

        In this report, we compare hot and ultraviolet (UV) embossing processes to fabricate hydrophobic surfaces with topological variance. In the hot embossing process, polypropylene was pressurized on a nickel mold with heat, while UV-curable polyurethane acrylate (PUA) was dispensed on the mold followed by UV exposure during the UV embossing process. Cylindrical micro-pillars were successfully replicated using two types of embossing processes with the same mold. The contact angles were then compared at various pillar diameters and with different embossing processes. Although the materials and embossing techniques were different, we achieved a contact angle (CA) enhancement of about 40%. The water contact angle of a transferred substrate, fabricated by the UV embossing process, was 138o. This was much higher than that of flat UV-cured PUA (78o). In addition, we fabricated reverse pillar-shape packing materials for good wettability and then compared the CA values. With the reverse-shape model,we were able to enhance the wettability and decrease the degree of hydrophobicity. This will be beneficial for lipophilic packing materials. This oleophilic characteristic demonstrates enhanced lubrication capabilities as a retort curry packing material.

      • KCI등재

        Clinical Characteristics and Outcome of Acute Heart Failure in Korea: Results from the Korean Acute Heart Failure Registry (KorAHF)

        이상언,이해영,조현재,최원석,김호곤,최진오,전은석,김민석,김재중,황경국,채성철,백상홍,강석민,최동주,유병수,김계훈,박현영,조명찬,오병희 대한심장학회 2017 Korean Circulation Journal Vol.47 No.3

        Background and Objectives: The burden of heart failure has increased in Korea. This registry aims to evaluate demographics, clinical characteristics, management, and long-term outcomes in patients hospitalized for acute heart failure (AHF). Subjects and Methods: We prospectively enrolled a total of 5625 consecutive subjects hospitalized for AHF in one of 10 tertiary university hospitals from March 2011 to February 2014. Descriptive statistics were used to determine the baseline characteristics of the study population and to compare them with those from other registries. Results: The mean age was 68.5±14.5 years, 53.2% were male, and 52.2% had de novo heart failure. The mean systolic and diastolic blood pressures were 131.2±30.3 mmHg and 78.6±18.8 mmHg at admission, respectively. The left ventricular ejection fraction was ≤40% in 60.5% of patients. Ischemia was the most frequent etiology (37.6%) and aggravating factor (26.3%). Angiotensin converting enzyme inhibitors/ angiotensin receptor blockers, beta-blockers, and aldosterone antagonists were prescribed in 68.8%, 52.2%, and 46.6% of the patients at discharge, respectively. Compared with the previous registry performed in Korea a decade ago, extracorporeal membrane oxygenation (ECMO) and heart transplantation have been performed more frequently (ECMO 0.8% vs. 2.8%, heart transplantation 0.3% vs. 1.2%), and in-hospital mortality decreased from 7.6% to 4.8%. However, the total cost of hospital care increased by 40%, and one-year follow-up mortality remained high. Conclusion: While the quality of acute clinical care and AHF-related outcomes have improved over the last decade, the long-term prognosis of heart failure is still poor in Korea. Therefore, additional research is needed to improve long-term outcomes and implement cost-effective care.

      • 하와이 주민 및 쥐의 Hantaan virus 감염에 대한 혈청역학적조사

        이상언 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.3

        Korean hemorrhagic fever was known to the world for the first time during the Korean War and its causative agent, Hantaan virus was discovered by Lee in 1976. Following this discovery, it became apparent that similar diseases such as hemorrhagic nephrosonephritis in the Soviet Union, Nephropathia epidemica in Scandinavia, Epidemic hemorrhagic fever in China, and Epidemic nephritis in Eastern Europe are caused by Hantaan and related viruses. Therefore in 1982, WHO recommanded that the above mentioned diseases with different names should be refered to as Hemorrhagic fever with renal syndrome. Recent seroepidemiologic surveys show that closely related agents antigenically similar to Hantaan virus are widely distributed in the world to a much greater geographic extent than previously recognized. This study was to prove the existence of Hantaan virus infection among the residents and the rats in the Hawaiian islands that is located in the center of the Pacific Ocean and the results are summarized as follows: 1. Rattus rattus, Rattus, norvegicus, and Rattus exulans had antibodies against Hantaan virus in the proportion of 84 to 1,159(7.2%), 30 to 169(17%), and 12 to 202(5.9%) respectively. 2. Among 216 healthy Hawaiians, 4 persons had antibodies (1.9%). However, prevalence of antibody to Hantaan virus among Vector Control Personnel worked in Hawaii State Department of Health was 30.6%(11/36). 3. Hantaan virus antigen was not demonstrable in the lung tissues of antibody-positive rats. 4. Up to the present time, there was no patient ever diagnosed as Hemorrhagic fever with renal syndrome clinically in the Hawaiian islands. The results of this study indicate that Hantaan virus or similar virus exists in the Hawaiian islands and further study is needed to demonstrate the occurrence of HFRS patient and to isolate Hantavirus in this area.

      • KCI등재

        鬱證환자에게 용서프로그램을 활용한 五志相勝療法을 시행하여 호전된 1례

        이상언,노동진,박장호,이고은,박인숙,류영수,안민섭,정지호 대한한방신경정신과학회 2010 동의신경정신과학회지 Vol.21 No.2

        Yùzhèng(鬱證) comes from obstruction of qi by stress. The patient has depressed mood, irritable sign, chest discomfort, costal pain, angry state or some strange feeling on the throat. Oh-Ji-Sang-Seung(五志相勝) therapy is base on the theory of interrelation in five elements in oriental medicine. The contents of Oh-Ji-Sang-Seung(五志相勝) therapy include five subjugations of five emotions. Anxiety subjugates fear(思勝恐), fear subjugates joy(恐勝喜), joy subjugates pity(喜勝悲), pity subjugates anger(悲勝怒), and anger subjugates anxiety(怒勝思). Forgiveness program is a kind of psychological therapies to decrease the degree of anger and it is included in Oh-Ji-Sang-Seung(五志相勝) therapy. In this case, a female patient, 50 years old, who suffered from Yùzhèng(鬱證) with chest discomfort, irritable sign, easily angry state, depressed mood, hot flush, insomnia. We used Oh-Ji-Sang-Seung(五志相勝) therapy besides herbal medication, acupuncture to her condition got improved. Therefore we reported it for the treatment.

      • KCI등재

        흉요추 골절의 임상적 고찰

        이상언,송영석,김기택,선승덕,배대경 대한외상학회 1995 大韓外傷學會誌 Vol.8 No.1

        In recent years, the rate of the spine fracture tends to be increased year by year along with increasing rate of traffic and industrial accidents and it also related with also long life expectancy and increasing population of older people. The authors analysed the classifications of spine fractures and results, according to age, methods of treatment. The authors evaluated 98 patients of thoracolumbar spine fracture, who were admitted and managed at Dept. of orhtopeadic Surgery, Kyung Hee University, from January, 1992 to June, 1994. 1. Most frequ.ent injured level was $quot;$quot;T12 and Ll (69.4%), the most common causes of injury were fall down in younger patients(39.1%) & slip down in older patients(27.8%). 2. $quot;$quot;Compression fracture$quot;$quot; was the most common type of injuries which were classified by 3-column concept according to Denis & McAfee (41.8%). 3. In the treatment, conservative management was bed rest under hyperextension state for 3 weeks and cast or thorocolumbosacral orthosis brace was applied for 3-6 months. Elderly patients, especially female, were managed by calcium, calcitonin or hormone therapy for treatment of osteoporosis. Decompresive operation was performed with instrumentation through anterior, or posterior, or combined approach in unstable spine f racture. 4. The amount of encroachment on neural canal was 48.6% in Frankel Scale A,B, C, 26% in Frankel scale D, and 18% in Frankel scale E. 5. Improvement in frankel grade was 1.4 grade in average after operation. 6. Residual pain was remained 35 patients(64%) after the conservative management and 21 patients(49%) after operative management. In elderly patients, the osteoporotic spines were vulnerable to minor trauma, resulting in fracture with more than two level, while in younger patients, it occurred mainly by major trauma, in the single level with neurologic deficit. So it is important to prevent further damage, and an adequate management is needed immediately according to the patient's age, stability of fracture, and associated neurologic damage.

      • KCI등재

        Acrylic Cement Foreign Body and Thrombus in Right AtriumCausing Pulmonary Embolism after Percutaneous Vertebroplasty

        이상언,장성아,김민석,김송이,한정규,장호준,김용진,손대원,오병희,김경환 대한심장학회 2006 Korean Circulation Journal Vol.36 No.10

        A pulmonary embolism is a rare, but well described complication of percutaneous vertebroplasty; the majority ofcases are caused by acrylic cement. Here, for the first time, we report a case of pulmonary embolism due to a thrombusin the right atrium, which was caused by an acrylic cement foreign body in the right atrium and centralveins 6 years after percutaneous vertebroplasty. This case suggests that an acrylic cement foreign body should be consideredas a potential source of thrombus formation in patients that develop a pulmonary embolism following percutaneousvertebroplasty. (Korean Circulation J 2006;36:713-715)

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