요추간판탈출증으로 보존적 치료후 호전되지 않는 환자 6 례 보고

이삼로,김현중,변재영,안수기,이종덕,Lee, Sam-Ro,Kim, Hyun-Jung,Byun, Jae-Young,Ahn, Soo-Gi,Lee, Jong-Deok 대한침구의학회 2000 대한침구의학회지 Vol.17 No.3

Objectives : The purpose of this study is to observe the clinical characteristics of 6 patients who were not improved after admitted conservative treatment in this 311 patients. Methods : We retrospectivety reviewed 311 patients of Herniated Lumbar Intervertebral Disc which undenvent admitted conservative treatment from November 1997 to June 2000. 311 patients were diagnosed by computed tomography or magnetic resonance imaging in addition to physical examination. Other complications were not detected in 311 patients with Hemiated Lumbar Intervertebral Disc. In case that the scoliosis appeared to caused by severe pain, we included this scoliosis patient with the object of survey. Results : 1. In 6 patients who were not improved, 4 patients were large herniation and 2 patients were medium herniation. 2. In all of 6 patients, the angle of straight leg raising test was low and was not imporved unril discharge. 3. X-ray findings showed straightening in all of 6 patients, disc space narrowing in 3 of 6 patients. 4. X-ray findings showed scoliosis in 3 of 4 patients who were severe pain. 5. The onset was relarively long from 30 days to 7 years. 6. The age was relatively young from 10's to 30's. 7. The adimission date was ralatively long from 32 days to 105 days. Conclusions : In 6 patients, there were observed much volume of disc herniation, low angle of straight leg raising test, young people in an age group, straightening of x-ray finding.

백서(白鼠)에서 오공약침(蜈蚣藥鍼)이 신경병증성(神經病症性) 통증(痛症)에 미치는 영향(影響)

이삼로,구성태,김성남,황우준,이건목,조남근,임규상,김성철,Lee, Sam-Ro,Koo, Sung-Tae,Kim, Sung-Nam,Hwang, Woo-Jun,Lee, Geon-Mok,Cho, Nam-Geun,Lim, Kyu-Sang,Kim, Sung-Chul 경락경혈학회 2004 대한침구의학회지 Vol.21 No.2

Objectives : In the present study, the effect of Scolopendrid Water-Alcohol Extract (SWAE) applied to acupuncture point BL23 (Shinsu) on the neuropathic pain was examined. A common source of persistent pain in humans is the neuropathic pain. Anti-convulsant drugs are used to treat the neuropathic pain. In the oriental medicine, Scolopendrid was used for long time to treat convulsant syndrome and back pain, etc. Methods : On the bases of the Scolopendrid clinical application, the effect of SWAE applied to the acupuncture point was tested in the rat model of neuropathic pain. Neuropathic pain was induced by tight ligation of L5 spinal nerve. When rats developed pain behaviors, One hundred microliter of SWAE was applied into the ipsilateral BL23 point at a dose of 10 mg/ml under enflurane anesthesia. The foot withdraw latency of the hind limb was measured for an indicator of pain level after each manipulation. Results : SWAE injection increased the mechanical threshold of the foot in the rat model of neuropathic pain significantly for the duration of 4h, suggesting a partial alleviation of pain. SWAE applied to BL23 point produced a significant improvement of mechanical sensitivity of the foot lasting for at least 4h. However, neither contralateral BL23 point, ST25 (Chonchu) point, nor LR3 (Taechung) point produce as much increase of mechanical sensitivity as ipsilateral BL23 point. And, this increase of mechanical sensitivity was dose-dependent. The improvement of mechanical threshold was interpreted as an analgesic effect. In addition, the analgesic effect of Scolopendrid 4 mg/kg injection is equivalent to that of gabapentin 50 mg/kg injection. The relations between SWAE-induced analgesia and endogenous nitric oxide(NO), inducible NO synthase (iNOS)/neuronal NO synthase (nNOS) were also examined. Results were turned out that both NO production and nNOS/iNOS protein expression which are increased by nerve injury were suppressed by SWAE injection applied to BL23 point. Conclusions : The data suggest 1) that SWAE produces a potent analgesic effect on the neuropathic pain model in the rat and 2) that SWAE-induced analgesia modulate endogenous NO through the suppression of nNOS/iNOS protein expression.

백서(白鼠)에서 오공약침(蜈蚣藥鍼)이 신경병증성(神經病症性) 통증(痛症)에 미치는 영향(影響)

이삼로 ( Sam Ro Lee ),김성철 ( Sung Chul Kim ),구성태 ( Sung Tae Koo ),김성남 ( Sung Nam Kim ),황우준 ( Woo Jun Hwang ),이건목 ( Geon Mok Lee ),조남근 ( Nam Geun Cho ),임규상 ( Kyu Sang Lim ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.2

Objectives: In the present study, the effect of Scolopendrid Water-Alcohol Extract (SWAE) applied to acupuncture point BL23 (Shinsu) on the neuropathic pain was examined. A common source of persistent pain in humans is the neuropathic pain. Anti-convulsant drugs are used to treat the neuropathic pain. In the oriental medicine, Scolopendrid was used for long time to treat convulsant syndrome and back pain, etc. Methods: On the bases of the Scolopendrid clinical application, the effect of SWAE applied to the acupuncture point was tested in the rat model of neuropathic pain. Neuropathic pain was induced by tight ligation of L5 spinal nerve. When rats developed pain behaviors, One hundred microliter of SWAE was applied into the ipsilateral BL23 point at a dose of 10 mg/ml under enflurane anesthesia. The foot withdraw latency of the hind limb was measured for an indicator of pain level after each manipulation. Results: SWAE injection increased the mechanical threshold of the foot in the rat model of neuropathic pain significantly for the duration of 4h, suggesting a partial alleviation of pain. SWAE applied to BL23 point produced a significant improvement of mechanical sensitivity of the foot lasting for at least 4h. However, neither contralateral BL23 point, ST25 (Chonchu) point, nor LR3 (Taechung) point produce as much increase of mechanical sensitivity as ipsilateral BL23 point. And, this increase of mechanical sensitivity was dose-dependent. The improvement of mechanical threshold was interpreted as an analgesic effect. In addition, the analgesic effect of Scolopendrid 4 mg/kg injection is equivalent to that of gabapentin 50 mg/kg injection. The relations between SWAE-induced analgesia and endogenous nitric oxide(NO), inducible NO synthase (iNOS)/neuronal NO synthase (nNOS) were also examined. Results were turned out that both NO production and nNOS/iNOS protein expression which are increased by nerve injury were suppressed by SWAE injection applied to BL23 point. Conclusions: The data suggest 1) that SWAE produces a potent analgesic effect on the neuropathic pain model in the rat and 2) that SWAE-induced analgesia modulate endogenous NO through the suppression of nNOS/iNOS protein expression.

화타협척혈에 대한 문헌적 고찰

안수기,이삼로,양유선,Ahn, Soo-Gi,Lee, Sam-Ro,Yang, You-Sun 대한침구의학회 2000 대한침구의학회지 Vol.17 No.4

Objectives : Hua-Tuo-Jia-Ji-Xue(華佗夾脊穴) is the Jing-Wai-Qi-Xue(經外奇穴) that is widely used in clinic and effective in Acupuncture and Moxibustion. But the location, number, acupuncture method, clinical application of Hua-Tuo-Jia-Ji-Xue have not been explained clearly and consistently; moreover, studies or clinical reports about this are insufficient. The purpose of this study is to investigate the location, number, acupuncture method, clinical apptication of Hua-Tuo-Jia-Ji-Xue. Methods : We investigated Hua-Tuo-Jia-Ji-Xue through survey of 11 books and 26 relevant journals published in China Results : 1. Hua-Tuo-Jia-Ji-Xue is located in about 0.5 Cun(寸) at both sides of spinous process of each vertebra. 2. There is differ as the number of Hua-Tuo-Jia-Ji-Xue is 34, 48, 56, 58 in each documents. Hua-Tuo-Jia-Ji-Xue located in first, second cervical vertebra and first sacrum is low in application frequency, Hua-Tuo-Jia-Ji-Xue located from third cervical vertebra to fourth lumbar vertebra is high in apptication frequency. Therefore, all of the acupoints located in about 0.5 Cun(寸) both sides of spinous process of cervical, thoracic, lumbar and sacral vertebrae are regarded as Hua-Tuo-Jia-Ji-Xue in wide meaning. 3. There are Kou-Ci-Fa(叩刺法), Qian-Ci-Fa(淺刺法), Yan-Pi-Ci-Fa(沿皮刺法), Shen-Ci-Fa(深刺法) in acupuncture method of Hua-Tuo-Jia-Ji-Xue. Acupuncturing depths, directions is differ in each location(cervical, thoracic, lumbar vertebra, sacrum) and have something to do with therapeutic effect of Hua-Tuo-Jia-Ji-Xue. The feeling that patient receive after acupuncture is the key to the treatment of disease. 4. The clinical application of each Hua-Tuo-Jia-Ji-Xue is mainly selected by distribution of meridians, nerve roots, vertebral segments which are attacked with a disease. The musculoskeletal diseases in treatment of disease by Hua-Tuo-Jia-Ji-Xue are the most common as 12 cases. Second, there are many reports about nervous system diseases. In addition, good therapeutic results by application of Hua-Tuo-Jia-Ji-Xue are reported in some diseases, for instance, diseases of five viscera and six entrails, organ, tissue Conclusions : Hua-Tuo-Jia-Ji-Xue is located in about 0.5 Cun(寸) at both sides of spinous process of each cervical, thoracic lumbar and sacral vertebra. Therapeutic effect of Hua-Tuo-Jia-Ji-Xue has something to do with acupuncturing depths, directions and feelings. Hua-Tuo-Jia-Ji-Xue is mainly selected by distribution of meridians, nerve roots, vertebral segments which are attacked with a disease and is mainly applied musculoskeletal diseases, nervous system diseases.

척추전방전위증의 한방 치료에 관한 임상적 고찰

김현중,이삼로,변재영,안수기,Kim Hyun-Jung,Lee, Sam-Ro,Byun Jae-Young,Ahn Soo-Gi 대한침구의학회 2000 대한침구의학회지 Vol.17 No.3

Objectives : This study was performed to evaluate the clinical results of the spodylolisthesis patients treated with oriental medical methods. Methods : We diagnosed spondylolisthesis by L-spine simple x-ray. 28 patients with spondylolisthesis were hospitalized at WonKwang University KwangJu Oriental Medical Hospital from April 1997 to January 2000 and treated by acupuncture, moxibustion, bed rest, herb-medicine and physical therapy. Results : 1. Distribution showed female predominence(82.1%) in general. 2. In the duration of symptoms, the largest group was the group of "acutest" (32.1%). 3. In the distribution of causes, the largest group was "overwork" (35.7%). 4. Isthmic type is the most common(75%) in etiology. 5. Isthmic type involved the 5th lumbar vertebra in 57.1% and degenerative type involved the 4th lumbar vertebra in 57.1%. 6. Most of cases were grade I(96.4%) in degree of slipping. 7. The common symptoms were radiating pain(92.9%) and low back pain(78.6%). 8. Therapeutic efforts above "good" by Kim's criteria was 20 cases(71.4%) Conclusions : The result of treatment by oriental medical methods is satisfactory for the treatment of spondylolisthsis.

정맥혈관내(靜脈血管內) 헬륨-네온 레이저 조사(照射)가 메리디안 심(心)·순환(循環) 대표점(代表點)과 고지혈증(高脂血症)에 미치는 영향(影響)

안수기,이삼로,황우준,Ahn, Soo-gi,Lee, Sam-ro,Hwang, Woo-jun 사상체질의학회 1998 사상체질의학회지 Vol.10 No.1

The purpose of this study was to investigate the effect of ILIB(Intravenous Laser Irradiation of blood) on Meridian-Heart Circulation CMP and Hyperlipidemia. Circulatory symptom of 20 patients was treated with ILIB. After 10 times' treatment, changes of total cholesterol, HDL-cholesterol, triglyceride and Meridian-Heart Circulation CMP value were observed. The results were as follows : 1. In observation of Meridian-Heart Circulation CMP value, significant increase was observed in both pre-ID generation and post-ID generation. So, distinctive observation between pre-ID generation and post-ID generation became not relatively significant. 2. In observation of Meridian-Heart Circulation CMP value, significant increase was observed in both left and right. So, distinctive observation between left and right became not relatively significant. 3. In observation of Meridian-Heart CMP value, significant increase was not observed in control group, but significant increase close to normal value was observed in treatment group after treatment of Intravenous He-Ne Laser Irradiation. 4. In observation of Meridian-Circulation CMP value, significant increase was not observed in control group, but significant increase close to normal value was observed in treatment group after treatment of Intravenous He-Ne Laser Irradiation. 5. In concentration of plasma total cholesterol and plasma triglyceride, significant decrease was not observed in control group, but significant increase was observed in treatment group after treatment of Intravenous He-Ne laser Irradiation. 6. Significant concentration change of plasma HDL-cholesterol was not observed in both control group and treatment group. From above results, it was thought that Intravenous He-Ne Laser Irradiation was significant effect on heart circulatory system in human body.

Meralgia Paresthetica 치료(治療) 1례에(例) 대한 증례보고

나건호,박은주,신정철,이동현,이삼로,류충열,윤여충,조명래,Na, Gun-ho,Park, Eun-ju,Shin, Jeong-cheol,Lee, Dong-hyun,Lee, Sam-ro,Ryu, Chung-ryul,Yoon, Yeo-choong,Cho, Myung-rae 대한침구의학회 2005 대한침구의학회지 Vol.22 No.1

대퇴부 작열감, 동통, 부종을 주소로 내원한 환자 1례를 대상으로 점액낭염에 의한 meralgia paresthetica의 진단 하에 한방적 치료를 시행하여 임상 양상을 관찰한 결과 다음과 같은 결론 을 얻었다. 1. meralgia paresthetica는 포착성 신경병증으로 외측 대퇴 피 신경이 압박되거나 손상되어, 대퇴부 전외측에 감각 저하, 이상 감각 및 작 열감을 호소하는 질환이다. 2. meralgia paresthetica는 한방적으로 '비병(痺病)', '마목(麻木)' 등의 범주에 해당하며 양혈산한통락(養血散寒通絡)의 치법을 활용할 수 있다. 3. 통비(痛痺)와 착휘(着輝)에 해당하는 meralgia paresthetica환자에게 가미활혈탕(加味活血湯) 투여 및 환측(患側)의비관(?關) 복토(伏兎) 충문(衝門) 풍시(風市) 족삼리(足三里) 등의(等) 혈위(穴位)에 자침(刺針)과 습식부항(濕式附缸)을 시술하여 6일만에 현저한 치료 효과를 보았다. 4. 환자는 고관절의 ROM에 있어서 초진시 신전제한 $60^{\circ}$였으나, 5회의 치료 후 신전제한 $0^{\circ}$로 회복되었으며 퇴원시 대퇴부 인통(引痛), 부종(浮腫), 발열(發熱) 등의 증상이 모두 경감되었다.

견인요법(牽引療法)을 병용한 요통(腰痛) 및 요각통(腰脚痛) 환자 40례(例)의 임상적 고찰

이동현,박은주,신정철,나건호,위통순,이삼로,류충열,조명래,채우석,윤여충,Lee, Dong-hyun,Park, Eun-ju,Shin, Jung-chul,Na, Gun-ho,Wei, Tung-shuen,Lee, Sam-ro,Lyu, Chung-yeol,Cho, Myung-rae,Chae, Wu-suk,Yoon, Yeo-choong 대한침구의학회 2004 대한침구의학회지 Vol.21 No.5

Objectives : The purpose of this report is to use more Traction treatment clinically by comparing th Improvement of Low Back Pain and Sciatica between Common treatment Group and Common treatment with Traction treatment. Methods : This study was carried out on 40 patients with Low Back Pain and Sciatica who were hospitalized in Dongshin Univ. Oriental Hospital from January, 2003 to May, 2004. Group A of 20 patients were taken both common treatment and Traction treatment. And Group B of 20 patients were only taken common treatment. And at discharge day, we checked and compared VAS(Visual Analogue Scale) and ODI(Oswestry disability index) out of these two groups. SPSS(Statistical Program for Social Science) for Window was used for a statistical analysis and the independent T-test was performed to gauge the improvement of VAS(Visual Analogue Scale) and ODI(Oswestry disability index) out of these two groups, in which case, value of P below 0.05 is considered as useful. Results : The result of the VAS(Visual Analogue Scale) and ODI(Oswestry disability index) of comparison analysis between two groups at discharge day, shows that the improvement of Low Back Pain and Sciatica in cmmon treatment with Traction treatment Group is more effective than that in Common treatment.