각막 간질내 공기 주입과 평형염액 주입이 간질세포 자멸사에 미치는 영향 비교

이민정,이현주,위원량,이진학,김미금,Min Joung Lee,M,D,Hyun Ju Lee,Won Ryang Wee,M,D,Jin Hak Lee,M,D,Mee Kum Kim,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.4

Purpose: To evaluate the effects of intrastromal air injection and intrastromal balanced salt solution (BSS) injection on corneal keratocyte apoptosis. Methods: Twelve right eyes of New Zealand White rabbits were divided into an air-injected group (n=6) and a hydro-injected group (n=6). Contralateral eyes served as a control. Air or Balanced salt solution (BSS?, Alcon, USA) was injected into the deep corneal stroma at the paracentral area to propagate into nearly the entire cornea. To reduce the intraocular pressure, anterior chamber paracentesis was performed. The animals were sacrificed 4 hours (n=6) and 24 hours (n=6) after surgery. Central cornea buttons were retrieved to stain with Hematoxylin & Eosin and TUNEL (Apoptag?, Chemicon). The mean number of apoptotic keratocytes was counted in 24.67±4.04 consecutive high power field (HPF). Results: The mean number of TUNEL-positive cells at 4 hours was 12.85±7.25/HPF and 0.25±0.44/HPF in air-injected and hydro-injected eyes, respectively. It was reduced to 6.25±4.02/HPF and 0.15±0.37/HPF in air-injected and hydro-injected eyes after 24 hours. The air-injected group showed significantly more TUNEL-positive cells compared with the hydro-injected or control group until 24 hours (p=0.001, p=0.001, Mann-Whitney U test). Conclusions: Intrastromal air injection induces significant apoptosis of keratocytes suggesting some damages in the peripheral cornea when used in deep lamellar keratoplasty.

112, 119 긴급신고 대응 지능화 기술 개발 동향

이민정,박현호,백명선,권은정,변성원,박영수,정의석,박혜숙,M.J. Lee,H.H. Park,M.S. Baek,E.J. Kwon,S.W. Byon,Y.S. Park,E.S. Jung,H.S. Park 한국전자통신연구원 2023 전자통신동향분석 Vol.38 No.3

Emergency numbers, such as 112 and 119, are used in many countries to connect people in need with emergency services such as police, fire, and medical assistance. We describe development directions of intelligent response technology for emergency calls. The development of this technology refers to enhancing the efficiency and effectiveness of response systems by using advanced methods such as artificial intelligence, machine learning, and big data analytics. We focus on a system that assists the receptionist of an emergency call. In the future, the recognition rate and decision-making accuracy of intelligent response technologies should be improved considering characteristics of public safety and emergency domain data. Although the current technology remains at the level of assisting a receptionist, a fully autonomous response technology is expected to emerge in the future.

과민성 방광을 동반한 쇼그렌 증후군 소양인 환자 치험 1례

이민정,박민영,황민우,Lee, Min-jung,Park, Minyoung,Hwang, Min-woo 사상체질의학회 2020 사상체질의학회지 Vol.32 No.3

Introduction This study aims to report a significant improvement of Sjögren's syndrome patient with irritable bladder, diagnosed as 'Soyangin chest-binding symptomatology' based on Sasang medicine. Methods The patient had treatment with 'Dojeokganggi-tang' and western medications. We evaluated the treatment outcome of Sjögren's syndrome symptoms by using a numerical score of 0 to 10, based on the patient's subjective discomfort of dry eye and dry mouth, and irritable bladder symptoms by recording the number of night urination every month. Results Sjögren's syndrome symptoms were significantly improved, and the number of night urination was decreased. After 41 weeks of treatment, the patient didn't have dry mouth any more and had only a little dry eye. The number of night urination was decreased from 3-4 times to once a night. Discussion The patient diagnosed with Sjögren's syndrome, treated with Dojeokganggi-tang and western medications for 41 weeks, showed a significant improvement in dry eye, dry mouth, and night urination compared to the first visit.

아르곤레이저 치료후 재발한 중심와아래 맥락막신생혈관에 대한 광역학치료

이민정,송수정,정흠,유형곤,Min-Joung Lee,M,D,Su-Jeong Song,M,D,Hum Chung,M,D,Hyeong-Gon Yu,M,D 대한안과학회 2005 대한안과학회지 Vol.46 No.12

Purpose: To evaluate the effects of photodynamic therapy for subfoveal recurrences of juxtafoveal or extrafoveal choroidal neovascularization (CNV), previously treated with argon-laser photocoagulation. Methods: Seven eyes, previously treated with argon-laser photocoagulation for juxtafoveal or extrafoveal choroidal neovascularization, received photodynamic therapy for subfoveal recurrence. Changes in visual acuity and fluorescein angiographic findings were analyzed. Results: The average time of appearance of recurrent CNV after laser photocoagulation was 43.14±29.62 months (range, 2-77 months). After photodynamic therapy, fluorescein leakage and neovascular lesion size decreased in all patients on fluorescein angiography. Visual acuity was stabilized or improved in 5 of 7 eyes. Conclusions: Photodynamic therapy was effective in patients with subfoveal recurrences of juxtafoveal or extrafoveal choroidal neovascularization previously treated with argon-laser photocoagulation.

특허 인용 네트워크 분석

이민정,김용대,장원철,Lee, Minjung,Kim, Yongdai,Jang, Woncheol 한국통계학회 2016 응용통계연구 Vol.29 No.4

과학 기술의 발전은 사회를 급격하게 변화시켜 왔다. 특허 자료 분석은 현대 과학 기술의 흐름을 이해하고 미래 유망기술을 예측할 수 있게 한다. 본 연구에서는 기술의 동향을 파악하고자 1985년과 2012년 사이에 미국 특허청에 등록된 특허를 중심으로 특허 인용 네트워크를 분석한다. 주요 기술군을 파악하기 위해 PageRank 알고리즘 외에 다양한 중심성 지표를 이용하고, 통계적 네트워크 모형을 통해 유사한 기술들의 군집을 찾아내고자 한다. The development of technology has changed the world drastically. Patent data analysis helps to understand modern technology trends and predict prospective future technology. In this paper, we analyze the patent citation network using the USPTO data between 1985 and 2012 to identify technology trends. We use network centrality measures that include a PageRank algorithm to find core technologies and identify groups of technology with similar properties with statistical network models.

만성비염 환아의 수면의 질과 성장에 관한 임상적 연구

이민정,장규태,한윤정,Lee, Min-Jeong,Chang, Gyu-Tae,Han, Yun-Jeong 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.2

Objectives : The study was designed to find out the relationships between rhinitis, quality of sleep, growth among children with chronic rhinitis. Methods : This research was performed in 50 children from November 2007 to May 2008. We measured height, weight, body mass index of those children and asked to answer to the questionnaires that consist of nasal symptoms, period of time with rhinitis, sleep symptoms, parent's height, present illness, and medical history. We also analyzed correlations with this factors obtained from questionnaires. Results : 1. In 50 subjects, there were significant correlations between nasal obstruction, the quality of sleep, and the between quality of sleep and growth. But, there were not significant correlations between nasal symptoms and growth. 2. In 24 preschool children, frequency of waking up during sleeping and the number of snorers were higher and quality of sleeping was worse than those in the children who were attending school. And there were significant correlations between quality of sleep and nasal obstruction. An average of RH-MPH(Recent Height-Mid-Parental Height) is $-7.74{\pm}36.51(%)$ which means they aren't as tall as MPH(Mid-Parental Height). 3. In 26 school children, there were significant correlations between symptoms and period of rhinitis, quality of sleep and growth. Conclusions : Children with chronic rhinitis have low quality of sleep and low growth. But more studies are needed.

다직종 암환자 교육·상담에 대한 설문 개발과 환자 만족도 조사

이민정,금민정,김재송,김수현,손은선,이상글,송수경,최혜진,Lee, Min Jeong,Geum, Min Jung,Kim, Jae Song,Kim, Soo Hyun,Son, Eun Sun,Lee, Sang Geul,Song, Su Kyung,Choi, Hye Jin 한국임상약학회 2018 한국임상약학회지 Vol.28 No.2

Background: Presently, a multidisciplinary team of doctors, pharmacists, nurses, and dietitians provides patient education to impart information on chemotherapy. However, studies on multidisciplinary education satisfaction are inadequate. In this study, we aimed to contribute to the improvement of quality of multidisciplinary education counseling for patients with cancer by developing a satisfaction questionnaire and analyzing the satisfaction survey. Methods: A questionnaire was developed by an expert group, and the responses were recorded using the 5-point Likert scale. After conducting a pre-test, factor analysis was performed to evaluate validity. The reliability of the questionnaire was measured by Cronbach's alpha coefficient. A satisfaction survey was conducted by self-administration method. Results: Based on the results of factor analysis, factors can be divided into two parts: "overall education" and "each team member's education" (total 14 questions). The construct validity and reliability of the questionnaire are sufficiently high. Fifty-one patients took the survey between January 2, 2018 and January 20, 2018. Twenty-six (51%) patients responded that they were "very satisfied" and 22 (43.1%) patients responded that they were "satisfied". Conclusion: By developing a questionnaire on multidisciplinary education counseling for patients with cancer, it is possible to perform evaluation and research of cancer patient education. This study will contribute to the management and improvement of quality of multidisciplinary education.

반응 온도에 따른 CoO/Co(OH)₂ 나노시트의 합성

이민정,윤가영,류경희,Minjeong Lee,Gayoung Yoon,Gyeong Hee Ryu 한국재료학회 2023 한국재료학회지 Vol.33 No.5

Transition metal oxides formed by a single or heterogeneous combination of transition metal ions and oxygen ions have various types of crystal structures, which can be classified as layered structures and non-layered structures. With non-layered structures, it is difficult to realize a two-dimensional structure using conventional synthesis methods. In this study, we report the synthesis of cobalt oxide into wafer-scale nanosheets using a surfactant-assisted method. A monolayer of ionized surfactant at the water-air interface acts as a flexible template for direct cobalt oxide crystallization below. The nanosheets synthesized on the water surface can be easily transferred to an arbitrary substrate. In addition, the synthesizing morphological and crystal structures of the nanosheets were analyzed according to the reaction temperatures. The electrochemical properties of the synthesized nanosheets were also measured at each temperature. The nanosheets synthesized at 70 ℃ exhibited higher catalytic properties for the oxygen evolution reaction than those synthesized at other temperatures. This work suggests the possibility of changing material performance by adjusting synthesis temperature when synthesizing 2D nanomaterials using a wide range of functional oxides, resulting in improved physical properties.

학술 6 - 산화적 스트레스 및 항산화제에 관하여(1)

이민정,Lee, Min-Jeong 대한수의사회 2012 대한수의사회지 Vol.48 No.4

성조숙증(性早熟證)에 관한 연구의 최근 동향;최근 중의(中醫) 잡지를 중심으로

이민정,장규태,한윤정,Lee, Min-Jeong,Chang, Gyu-Tae,Han, Yun-Jeong 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.1

Objectives The aim of this study was to investigate the treatment of precocious puberty in current traditional Chinese medical journals. Methods To figure out diagnosis methods, treatment methods, treatment effects of oriental medicine about precious puberty, Chinese medical journals from China National Knowledge Infrastructure (CNKI) which was published from 1999 to 2007 were analyzed and precocious puberty was also been searched. Results 82 articles were selected. 1. Yin and purging Fire(滋陰瀉火) from traditional Chinese Medicine was usually used. 2. The herbs were almost used such as Rehmannia glutinosa(地黃), Anemarrhena asphodeloides (知母), Phellodendron amurense(黃柏), Thesium chinense(夏枯草), Paeonia suffruticosa Andrews(牧丹皮), Alisma canaliculatum(澤瀉), Testudinis Plastrum(龜板), Paeonia japonica(白芍藥), Bupleurum falcatum(柴胡), Genianae Scabrae Radix(龍膽草). 3. The total improvement rate was 72.50 to 100% Conclusions The oriental medical treatments for precocious puberty were presumed to be effective, but more studies are still needed.