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이명원,안정현,경성은,이동초,Myung Won Lee,Jung Hyun Ahn,Sung Eun Kyung,Dong Cho Lee 대한안과학회 2007 대한안과학회지 Vol.48 No.9
Purpose: The purpose of this case report is to describe accompanying ocular findings, especially optic neuropathy, in a patient with MELAS syndrome. Methods: A 10-year-old male patient who had lactic acidosis and neurological symptoms (loss of consciousness, vomiting, epilepsy, decreased vision, and constricted visual field), underwent a brain magnetic resonance imaging (MRI) scan and a molecular genetic analysis. Results: A diagnosis of cerebral infarction due to occlusion in the right posterior cerebral artery was made and confirmed by MRI scan. The diagnosis of MELAS syndrome was confirmed by performing molecular genetic analysis demonstrating the transformation of the mitochondrial tRNAleu(UUR) gene (MTTL1) A to G(3243). According to the ocular examinations, the patient??s left eye showed decreased vision, hemianopsia, relative afferent pupillary defects, mild swelling of optic nerve, and decreased amplitude on visual evoked potential exam. Conclusions: We encountered a case of MELAS syndrome involving optic neuropathy, which can (although rarely) occur with this syndrome. Therefore, in patients with an optic neuropathy of uncertain etiology, clinicians should consider performing comprehensive ocular exams and molecular genetic exams to rule out the possibility of genetic diseases.
새로운 시신경 테 너비의 규칙을 이용한 정상안과 녹내장안의 구별
이명원,신종훈,기창원,Myung Won Lee,Jong Hoon Shin,Chang Won Kee 대한안과학회 2014 대한안과학회지 Vol.55 No.1
Purpose: To evaluate the diagnostic ability of the modified ISNT rule (disc rim thickness of the smaller of inferior and superior > the larger of nasal and temporal) for normal and glaucomatous eyes compared to the classic ISNT rule (disc rim thickness of inferior > superior > nasal > temporal). Methods: Color stereo optic disc photographs of 113 normal subjects and 108 open angle glaucoma patients with early and moderate stage were morphometrically evaluated. The classic ISNT rule and the modified ISNT rule were assessed by masked evaluation of disc photographs at the 3, 6, 9 and 12 o’clock positions. Results: Among normal subjects, 58 of 113 eyes (51.3%) were normal and in open angle glaucoma patients, 104 of 108 eyes (96.3%) were abnormal with the classic ISNT rule. Among normal subjects, 98 of 113 eyes (94.2%) were normal and in open angle glaucoma patients, 102 of 108 eyes (94.4%) were abnormal with the modified ISNT rule. The modified ISNT rule was more accurate than the classic ISNT rule in terms of Cohen’s Kappa analysis used for discriminating between normal and glaucomatous eyes. Conclusions: The modified ISNT rule is useful for differentiating between normal and glaucomatous optic nerves and easily applied in clinical practice. J Korean Ophthalmol Soc 2014;55(1):93-101
이명원,이동초,장무환.Myung Won Lee. M.D.. Dong Cho Lee. M.D.. Moo Hwan Chang. M.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.7
Purpose: This clinical report describes the characteristics and ophthalmic treatment of a patient with anhidrotic ectodermal dysplasia showing bilateral upper eyelid entropion, conjunctival mass and dry eye syndrome. Methods: A 12-year-old boy presented to our clinic complaining of a white mass on the lower tarsal conjunctiva, foreign body sensation, and an itching in his right eye of one-year duration. He had developmental defects in his hair, teeth, nails and sweat glands. He had dry skin, a flat upper-lip, heat intolerance, a saddle-backed nose, and hypohidrosis. Ophthalmic examination showed blepharitis, a conjunctival mass, and bilateral upper eyelid entropion. Results: Upper eyelid entropion surgery was performed. An excisional biopsy of the conjunctival mass showed nonspecific acute and chronic inflammation. Conclusions: We concluded that the conjunctival mass developed as a result of chronic inflammation caused by chronic conjunctivitis and dry eye syndrome. Regular lid-hygiene with swab and lubrication is useful to minimize recurrent ocular inflammation in anhidrotic ectodermal dysplasia.
유리체강내 트리암시놀론 주입술 후 예방적 안압하강제의 효과
이명원,경성은,장무환.Myung-Won Lee. M.D.. Sung Eun Kyung. M.D.. Moo-Hwan Chang. M.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.5
Purpose: The purpose of this study was to investigate the prophylactic effect of brimonidine 0.15% on intraocular pressure (IOP) elevation and the risk factors for its elevation after intravitreal triamcinolone acetonide injection (IVTA). Methods: A prospective, randomized clinical trial was conducted on 67 eyes of 64 patients undergoing IVTA. Eyes were randomly divided into two groups, those which had used brimonidine 0.15% (40 eyes) and those which had not used it (27 eyes). IOP was measured preoperatively, at one week, and monthly until six months post-injection in each group. Results: The mean post‐injection IOP at one week was 11.93±3.36 mmHg for the group that had used brimonidine and 13.58±3.25 mmHg for the group that had not used it. The difference between the two groups was statistically significant at one week (p=0.049), but others were not statistically significant. An elevation in the IOP of more than 22 mmHg was seen in 8 eyes (20%) in the group using brimonidine and in 7 eyes (25.9%) in the group not using brimonidine. There was no difference in the incidence of IOP elevation between the two groups. Conclusions: Prophylactic use of brimonidine 0.15% will prevent sudden IOP elevation and will, therefore, prevent damage to the retina and optic nerve. However, in the long term, there is no prophylactic effect of brimonidine 0.15% on IOP elevation because there was no difference in the incidence of IOP elevation of more than 22 mmHg between the two groups.
AMEPD 구동을 위한 펜타센 OTFT backplane 제작
이명원(Myung Won Lee),류기성(Gi Sung Ryu),김영배(Young Bae Kim),송정근(Chung Kun Song) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.7
We fabricated flexible OTFT-backplanes for the electrophoretic display (EPD). The size of backplane was 2.5" in diagonal direction and consisted of 128×96 pixels, containing 1 OTFT in each pixel. The backplanes were batch-processed on 200㎜×200㎜ PEN substrate which included four backplanes. The OTFTs employed bottom contact structure and used the cross-linked polyvinylphenol for gate insulator, pentacene for active layer. Especially. we used PVA/Acryl double layers for passivation of backplane as well as for interlayer between backplane and EPD panel. The OTFT-EPD panel worked successfully and demonstrated to display some patterns.
미용 성형 목적으로 반복적 보형물 주입술을 시행 받은 후 발생한 피부근염
이명원 ( Myung Won Lee ),윤소윤 ( So Youn Youn ),강소라 ( So Ra Kang ),이지수 ( Ji Soo Lee ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.1
Dermatomyositis and polymyositis are uncommon, acquired idiopathic inflammatory myopathies of an unknown etiology. Although there are 9 reported cases in the literature of developing dermatomyositis or polymyositis after collagen dermal injection, it is still controversial whether there is a link between injectable filler materials and autoimmune diseases, and specifically dermatomyositis/polymyositis. We experienced a case of a 40-year-old woman who developed dermatomyositis after repeated injections of multiple filler materials, including collagen for cosmetic purposes, which suggests a temporal relation between the two factors. The benefit-to-risk ratio should be assessed for repeated cosmetic surgical procedures that use filler materials.
탈근대, 탈식민, 탈민족 포스트 담론 20년의 성찰 문학의 탈정치화와 포스트 담론의 파장 -민주화 이후 한국문학의 전개와 쇠락
이명원 ( Myung Won Lee ) 고려대학교 민족문화연구원 2012 民族文化硏究 Vol.57 No.-
This paper is intended to analyze the issues of the influence so called ``post`` discourse made on Korean literature after the democratization. In order to understand the transformation of literature at this period, the relationship between the historical evolution in Korean society after the uprising in June 1987 and literature should be noted. There must be several reasons for the acceptance of the ``post`` discourse in Korean literary world. First, the decline of both national literature discourse which was a leading theory of the past era, and realism as a creative method could be one reason. In other words, this can be read as the tremendous interest in new foreign literature trend to overcome chaotic situation which lacked certain aesthetic view. Second, the fact that political democratization and economic growth have fairly progressed at this point should be considered. The ripening of democracy and the economic growth shifted the issue of literature from politics to culture. In sum, as the degrees of sensibilities and expression of desire in the realm of taste became main literary agenda, ``post`` discourse have been imported in various ways to explain that. Third, ``post`` discourse have been spread as a reaction to the global impact of Eastern European socialist bloc`s collapse. In a broader sense, this caused the decline of historicism. The issue of expressing and analyzing changed reality in literature was raised. Some young writers attempted to find the possibility of such issues within the ``post`` discourse. However, ``post`` discourse in Korea cannot be seen as a productive contribution to the literature not counting its rich critical questions. ``Post`` discourse in Korean literature mainly functioned as an alibi for hasty denial and settlement of the past. From the perspectives of creation, criticism, and research, the influences of ``post`` discourse including post-colonialism has high possibility of critical assessment. Critical reexamination on the theory from the elaborate awareness of Korean reality and literature is a literary attitude valid until today.