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전신성 경화증 환자에서 99m Tc - DTPA 폐제거율의 의의
이명권(Myung Kwon Lee),강영모(Young Mo Kang),배기범(Gi Bum Bae),박지현(Jee Hyun Park),이종명(Jong Myung Lee),이재태(Jae Tae Lee),김능수(Nung Soo Kim) 대한내과학회 2001 대한내과학회지 Vol.61 No.1
N/A Background: We measured the clearance rate of inhaled 99mTc-diethyl triaminepentaacetic acid (DTPA) aerosol in patients with systemic sclerosis. We also investigated its correlation with respiratory function test and acute phase reactant proteins. Methods : Ten patients with systemic sclerosis, ten patients with rheumatoid arthritis, and ten healthy controls were included. Dynamic scintigrams (20 seconds/frame, up to 30 minutes) were obtained following inhalation of 99mTc-DTPA aerosol through a radioaerosol delivery system. The time to half clearance (T1/2) was calculated from the time-activity curves. High resolution computed tomography, pulmonary function test and laboratory tests such as ESR, CBP, and complement (C3/C4) were performed. Results : 1) Mean T1/2 values of 99mTc-DTPA clearance after inhalation were 28.1±3.8, 57.9±20.9, and 64.3±13.0 minutes in systemic sclerosis, rheumatoid arthritis and normal controls, respectively. Mean T1/2 value in systemic sclerosis was significantly reduced compared with those of rheumatoid arthritis group (ρ<0.001) and normal controls (ρ =0.001). 2) No significant correlations were found between mean T1/2 and FEV1/FVC, FVC or DLco in patients with systemic sclerosis. 3) There was no significant corre4tion between mean T1/2 and ESR or CRP in patients with systemic sclerosis. And in patients with rheumatoid arthritis, mean T1/2, value correlated significantly with ESR and CRP. Conclusion ' The clearance rate of inhaled 99mTc-DTPA was significantly increased in patients with systemic sclerosis and had no significant correlation with pulmonary function test and acute phase reactants, but was found to have significant correlations with ESR and CRP in patients with rheumatoid arthritis. (Korean J Med 61:33-40, 2001)
정풍언,이명범,한주 漢陽大學校 文理科大學 化學科 1978 化脈 Vol.- No.6
인삼의 chloroform 추출물중에 항산화성 물질이 함유되어 있는지를 검토할 목적으로 해바라기 기름을 기질유로 사용하여 기질유의 자동산화에 미치는 인삼의 chloroform 추출물의 영향을 검토하여 다음과 같은 결과를 얻었다. 1. 인삼 chloroform 추출물의 첨가는 기질유의 산소흡수에 의한 무게의 증가를 억제하였고, 자동산화의 induction period 도 연장시켰다. 2. 인삼 chloroform 추출물의 첨가는 기질유의 자동산화를 억제시켜 대조구에 비해 유지 과산화물의 형성을 저하시켰다. 3. 인삼 chloroform 추출물의 첨가는 기질유의 요오드값의 감소를 적게 하였다. 본 실험은 백 태흥 교수님의 지도로 이루어진 것이며 시종 지도하여 주신 교수님께 심심한 사의를 표하며, 아울러 본 실험을 보살펴 주신 홍정태 조교에게 감사를 드린다.
홍성호,이명범,이만형 한국비교정부학회 2009 한국비교정부학보 Vol.13 No.1
Over a decade, interregional network has been one of the key topics in both academic and practical arenas. In the similar contexts, Korea government has actively adopted the paradigm based on the interregional competition and cooperation. Reflecting the ever-increasing social needs for the interregional network, this study analyzes dynamic network of 33 cities, counties, and districts within Chungcheong Jurisdiction between 2000 and 2005. The results imply that the size of the internal network within Chungcheong Jurisdiction becomes bigger, strengthening and the interconnectedness during the research period. The major changes overly originate from a handful of big cities. In contrast, the network disparity between the central and peripheral cities is getting increasingly worse over the time. Comparing the interprovincial connectedness, the internal network within a province becomes strengthened in the first half of 2000s. In terms of centrality, Youseong and Seo Districts within Daejeon Metropolitan Government function as main hubs of Chungcheong Jurisdiction. In addition, there has been no change in in-degree and out-degree ordering among the 9 regions holding a higher ranking. These research findings would contribute to systematic accumulation of urban information and strategic decision-making.