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밀리온 임상 다축 검사(MCMI)를 이용한 알코올의존 입원 환자의 아형 분류 연구
이덕기(Duk-Gi Lee),최진환(Jin-Hwan Choi),정봉주(Bong-Ju Jung),정순민(Sun-Min Jung) 한국중독정신의학회 2004 중독정신의학 Vol.8 No.2
Objectives:The purpose of this study is to classify the personality characteristics of individuals with alcohol dependence through cluster analysis, and to examine clinical characteristics of each subtype. Methods:402 Inpatients with alcohol dependence were received MCMI, AUI, MAST, and ADS. The classification of personality subtypes of alcohol dependence was done through the cluster analysis. Results:1) Personality characteristics of patients with alcohol dependence could be classified into three subtypes. Subtype 1 showed the most severe personality pathology. Subtype 2 showed the relatively milder personality pathology. Subtype 3 showed the intermediate level of personality pathology. 2) There is no difference in age, educational level, marital status, and the onset age of alcohol problem, and the existence or nonexistence of job, family history of alcoholism, medical disease, and smoking among three subtypes. 3) As a result of comparative analysis of alcohol-related variables, mental functioning, compulsive drinking, drinking problem, insight of problem, anxiety, and physical, psychological dependence showed statistically significant difference between subtype 1 and subtype 2 or 3. 4) There was a significant difference in anxiety, somatization, mania, alcohol dependence, posttraumatic stress symptom, thought disorder, major depression, and delusional disorder among three subtypes. There was a significant difference in the degree of drug abuse between subtype 1 and subtype 2 or 3. Conclusion:It is possible to classify personality characteristics of patients with alcohol dependence into three subtypes by means of MCMI in Korea.
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Risperidone에서 Clozapine으로 교체 도중 발생한 비정형 신경이완제 악성 증후군 1예
최진환(Jin-Hwan Choi),박영민(Young-Min Park),이덕기(Duk-Gi Lee) 대한생물치료정신의학회 2007 생물치료정신의학 Vol.13 No.1
Neuroleptic malignant syndrome(NMS) is rare but a potentially fatal side effect of antipsychotics. It is characterized by muscular rigidity, fever, autonomic instability, and altered consciousness. Because it may be a possible result of a precipitous reduction in dopamine receptor activation, the introduction of the atypical antipsychotics raised expectations that these drugs would not cause NMS. But many NMS cases associated with atypical antipsychotics, including clozapine, have been reported so far. We experienced a case of NMS which is thought to be caused by the use of clozapine. The patient was a 30 year-old man, and he has suffered for 13 years from disorganized schizophrenia with bizarre delusion, auditory hallucination and disorganized behavior. He was treated with various antipsychotics but none of them were effective enough to control the symptoms, so the drug was switched from risperidone to clozapine. We titrated clozapine up to 225㎎/d and tapered off risperidone to 1㎎/d, and physical and neurological condition were normal. On 27th days of clozapine treatment, the patient suddenly developed clouding of consciousness, tremor, severe muscular rigidity and enuresis, so all the medications were stopped. On the 29th days of clozapine treatment, the laboratory test showed abnormal results:creatine phosphokinase(CPK) 128IU/I, lactate dehydrogenase( LDH) 508 IU/I, aspartate aminotransferase(AST) 110IU/I, alanine aminotransferase(ALT) 116IU/I, and white blood cell(WBC) 13.7×10³/μL. The patient was treated with benztropine 3㎎/d and diazepam 10㎎/d, and his condition improved to show no sign of muscular rigidity and disorientation within a week, and the laboratory tests were normal including WBC, CPK and LDK. Five days later, the patient had sudden seizure attacks but there were nothing abnormal on magnetic resonance imaging scan, electrolytes and neurological tests. He started taking valproate, and afterward he had nothing abnormal on blood tests and neurological examinations with no seizure attacks.
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1910년대 신파극에 대한 탈식민주의적 고찰 : 관객의 문제를 중심으로 Focus on the Audience
이덕기 한국어문학회 2004 語文學 Vol.0 No.84
This paper examines the postcoloniality of 1910s Sinpa-guk. 1910s Sinpa-guk is first theatrical result of the discussion on the theatrical reform of Korean civilized period. Sinpa-guk had appeared on the stage with splendor as civil drama. Sinpa-guk play people stressed this assumption, at the same time, brought into relief authority of Japanese Sinpa-guk as civil drama. With this, 1910s Sinpa-guk strengthened authority of colonial power. But 1910s Sinpa-guk's prosperity didn't stand long. After middle 1910s, Sinpa-guk lost there their audience rapidly. Finally Sinpa-guk play people flattered popularity of motion pictures. The play combined moving picture is result of this attempt. As a result, the play combined moving picture pressed decline of Sinpa-guk. In early 1920s, Sinpa-guk barely kept itself in existence through effort that settled itself in Korean manners. Sinpa-guk play people made Korean audience object of reform with authority of Japanese Sinpa-guk. So Sinpa-guk spoke for colonial eye of colonial power with this. Whereupon Korean Sinpa-guk's audience reacted to the contradictory with unsuitable reaction. This reaction is applicable 'evil gaze' against 'colonial eye" from the point that it confused Sinpa-guk play people. Korean Sinpa-guk play people were confused between authority of Japanese Sinpa-guk and evil gaze of Korean audience. They regarded Korean audience as object of reform, but Korean audience isn't passive being. The audience led alteration of Korean Sinpa-guk in late 1910's. And Korean Sinpa-guk couldn't display authority of colonial culture any longer.
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