태연혈(太淵穴)의 유침 시간에 따른 체온 변화 -적외선체열촬영(赤外線體熱撮影)을 중심으로-

이봉효 ( Bong Hyo Lee ),이경민 ( Kyung Min Lee ),박지하 ( Ji Ha Park ),김민서 ( Min Seo Kim ),김산들 ( San Deul Kim ),박병규 ( Byeong Gyu Park ),양현동 ( Hyun Dong Yang ),예성호 ( Sung Ho Yea ),이호정 ( Ho Jung Lee ),최재원 ( Jae 경락경혈학회 2012 Korean Journal of Acupuncture Vol.29 No.2

Objectives: This study was performed to find the desirable remaining time of needle in the acupuncture treatment. Methods: The 21 volunteers were given acupuncture at LU9 vertically and needles were remained for 2 min, 10 min, 15 min, 30 min, respectively. The thermographic change induced by acupuncture was measured with Digital Infrared Thermographic Image at the following acupoints: LU11, LU10, LU9, LU8, LU5, LU1, and PC7. The statistical significance of thermographi change was evaluated using paired t-test and post hoc Wilcoxon test. Results: The most significant changes after acupuncture were produced when needles were remained for 10 min or 15 min. LU11, LU5, LU1, and PC7 were the point at which all of the remaining time produced significant change commonly. At LU11, the biggest change was produced when needle was remained for 15 min, while at LU5, LU1, and PC7, the biggest change was produced when needle was remained for 30 min, and the smallest change was produced when needle was remained for 10 min at all of acupoints of LU11, LU5, LU1, and PC7. The unbalance between left side and right was decreased the most largely in 15 min group. Conclusions: The results of this study suggest that the desirable remaining time of acupuncture needle might be 15 min.

탈지분유 함유 식이를 섭취하는 흰쥐에서 칼슘과 비타민 D 수준이 무기질 대사에 미치는 영향

이경민,이연주,원은숙,이상선,Lee, Kyung-Min,Lee, Yeon Joo,Won, Eun-Sook,Lee, Sang Sun 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.4

The purpose of this study was to investigate the effect of calcium (Ca) and vitamin D (vit. D) levels on metabolism of various minerals such as Ca, P, Mg, Fe, Zn, Cu, and Cr. The comparison was made on the rats that were placed on diet containing powdered skim milk with different Ca and vit. D levels for 5 weeks. A total of 42 5-week-old Sprague-Dawley rats were divided into 7 groups as follows: Control group consisted of normal Ca and normal vit. D (0.5% Ca, 1,000 IU vit. D); Experimental groups were divided into low (0.25%) and high (1.0%) calcium levels; and vit. D group was divided into low (10 IU), normal (1,000 IU), and high (5,000 IU) subgroups. The weight gain and food efficiency ratios of the rats were not significantly different with increasing dietary Ca levels. The absorption rates of 7 minerals (Ca, P, Mg, Fe, Zn, Cu, and Cr) were significantly decreased with increasing dietary Ca levels. Also, fecal excretion of P significantly increased with increasing dietary vit. D levels (p<0.05), and urine excretion of Fe was significantly increased with increasing dietary vit. D levels (p<0.001). The result indicated that higher Ca intake affected on bioavailability of other minerals, due to interactions among minerals in the process of intestinal absorption. However, vitamin D intake had no effect on bioavailability of several minerals. Therefore, it could be suggested that adequate Ca intake is important for balance of the minerals.

휴대형 자동, 수동형 및 탁상형 자동 각막곡률검사기로 측정한 각막곡률의 신뢰성

이경민,박신혜,신선영,Kyung-Min Lee,Shin-Hae Park,Sun-Young Shin 대한안과학회 2010 대한안과학회지 Vol.51 No.3

Purpose: To compare the keratometry measurements by the handheld Nikon Retinomax K-plus2, the on-table Canon RK-5 autokeratometer, and the manual Topcon OM-4 keratometer and to evaluate the degree of agreement among the three instruments. Methods: Adults (n=30) and children (n=40) presenting toa tertiary eye hospital clinic were examined by an optometrist. Topcon OM-4 keratometer, Nikon Retinomax and the on-table Canon RK-5 autokeratometer analyses were performed in order. The horizontal and vertical keratometry data were measured. The vector components of astigmatism, mean bias and agreement among the three types of measurements were evaluated. Results: There were no significant differences among the three keratometers in horizontal or vertical keratometry or in central corneal astigmatism in both the adult and child groups (p-value>0.05). The keratometers which were estimated with Retinomax K-plus2 were highly correlated with those by on-table RK-5 autokeratometer (min. 0.89, max. 0.97) and Topcon OM-4 keratometer (min. 0.67, max. 0.94) in the adult group, while in the child group, the three instruments showed slightly decreased correlation (min. 0.45, max. 0.97 on RK-5, min. 0.36, max. 0.92 on OM-4), especially in the left eyes. Conclusions: The handheld Retinomax K-plus2 provided comparable data to that of the conventional on-table Topcon and manual keratometers. This instrument will beuseful in the clinic to measure keratometry in children or immobilized patients who have difficulty sitting during the examination.

봉약침료법(蜂藥鍼療法)을 가미(加味)한 건선(乾癬) 치험(治驗) 1례(例)

이경민,윤현민,고우신,장경전,하지영,서정철,한상원,Lee, Kyung-min,Youn, Hyoun-min,Ko, Woo-shin,Jang, Kyung-jeon,Ha, Ji-young,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : Psoriasis is a common skin disease and the difficulty of its medical management is well known. This study was designed to investigate the effect of bee venom aqua-acupuncture on psoriasis. Methods : Bee venom aqua-acupuncture was performed two times a week. The following points were selected: LI-11(曲池), LI-15, K-9(築賓) on both sides of body. For herbal medicine, YanHyulJiHwangTang-gami was given. We checked involvement in plaque, erythematous popules and invasiveness according to psoriasis area severity index(PASI). Results :After 9 weeks of treatment, the patient showed that itching symptoms was disappeared and score of PASI changed from 26.2 to 0. Conclusions : These results suggest that bee venom aqua-acupuncture and herbal medicine has good effect on psoriasis. But further studies are required to concretely prove the effectiveness of bee venom aqua-acupuncture for treating psoriasis.

합금강관의 Energy Resistance Welding 용접조건에 따른 미세조직 거동 및 기계적 특성 연구

이경민,이동언,김성웅,윤병현,강희재,강남현,조경목,Lee, Kyung-Min,Lee, Dong-Eon,Kim, Sung-Woong,Yoon, Byung-Hyun,Kang, Hee-Jae,Kang, Nam-Hyun,Cho, Kyung-Mox 한국재료학회 2011 한국재료학회지 Vol.21 No.1

Energy resistance welding (ERW) is a pipe-producing process that has high productivity and low manufacturing cost. However, the high heat input of ERW degrades the mechanical property of the pipe. This study investigates the effect of heat input and alloying elements on microstructure and mechanical properties of ERW pipes. As the heat input increased, the ferrite amount increased. The ferrite amount in the weld centerline was larger than t at in the weld boundary. Medium carbon steels (S45C and K55) having 0.3~0.4wt.% carbon yielded a significant difference of ferrite amount in the weld centerline and weld boundary. High alloyed steels (DP780 and K55) having 1.5~1.6wt.% Mn showed a ferrite rich zone in the weld centerline. These phenomena are probably due to decarburization and demanganisation in the weld centerline. As the ferrite fraction increased, the hardness decreased a little for the S45C steels. In addition, DP780 steels and K55 steels showed that the hardness drops when those steels have a ferrite rich zone. But we demonstrated the good tensile property of the DP780 steels and K55 steels in which Mn is included.

자동차용 박강판 겹치기 이음부의 CO₂ 아크 용접에서 다중회귀분석기법을 이용한 용입깊이 예측에 대한 연구

이경민,심현우,권재형,윤북동,정민기,박문수,이보영,Lee, Kyung-Min,Sim, Hyun-Woo,Kwon, Jae-Hyung,Yoon, Buk-Dong,Jeong, Min-Ki,Park, Moon-Soo,Lee, Bo-Young 대한용접접합학회 2012 대한용접·접합학회지 Vol.30 No.2

Welding is an essential process in the automotive industry. Most welding processes that are used for auto body are spot welding and $CO_2$ welding are used in a small part. In production field, $CO_2$ welding process is decreased and spot welding process is increased due to welding quality is poor and defects are occurred in $CO_2$ welding process frequently. But $CO_2$ welding process should be used at robot interference parts and closed parts where spot welding couldn't. Because of the 0.65mm ~ 2.0mm thickness steel sheet were used in the automotive industry, poor quality of welding area such as burn through and under fill were happened frequently in $CO_2$ process. In this paper, we will study about the penetration depth which gives a huge impact on burn through changing a degree of base metal, welding position and torch angle. Voltage, current and welding speed were fixed but degree of base metal, welding position and torch angle were changed. And Cold- Rolled(CR) steel sheet was used. Penetration depth was analysed by multiple regression analysis to derive approximate calculations. And reliability of approximate calculations were confirmed through additional experiments. As the results of this research, we confirmed the effect of torch and plate angle to bead shape. And we present a possibility that can simulate more accurate to weld geometry, as deduced the verification equations that has tolerance of less than 21.69%.

위화(胃火) 1호(號)로 호전(好轉)된 만성위염(慢性胃炎) 환자(患者) 치험(治驗) 2례(例)

이경민,이세연,임성철,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Im, Sung-chul,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.6

Objective: This study was designed to investigate the effect of Wihwa herbal-acupuncture on chronic gastritis. Methods: Wihwa herbal-acupuncture was administered two times a week. The following points were selected: CV12(中脘), CV13(上脘), S36(足三里), Liv3(太衝). We checked pain rating score(P.R.S.), visual analogue scale (V.A.S.) and Gastroscopy. Results: After 6 weeks of treatment, the patient showed that clinical symtoms was disappeared, Lee's P.R.S. changed from 77 to 8 and Park's P.R.S. from 55 to 0 and gastric erosion disappeared on gastroscopy. Conclusions: These results suggest that and Wihwa herbal-acupuncture has good effect on chronic gastritis. But further studies are required to concretely prove the effectiveness of Wihwa herbal-acupuncture for treating chronic gastritis.

도서관의 전자정보실 서비스 개선을 위한 이용사례 분석

이경민,Lee, Kyung-Min 한국도서관정보학회 2009 한국도서관정보학회지 Vol.40 No.4

국내 도서관은 정보화 시대에 적응하기 위하여 이용자에게 컴퓨터 사용환경을 일찍부터 제공하였다. 하지만 오늘날은 컴퓨터 사용환경이 일반화되어 전자정보실에 대한 변화가 필요한 시점이다. 이에 문헌정보학과 학생 78명으로 하여금 직접 전자정보실을 이용해 보게 하여 이용에 편리한 점과 불편했던 점을 기술하게 하였다. 이용사례 결과를 분석하여 전자정보실의 바람직한 변화 방향을 찾고자 하였다. 그 결과 사서에 의해 제공되는 정보서비스에서 불만이 가장 많았고, 그 이외에 시설과 장비 그리고 공간 순으로 많았다. 이를 개선하기 위한 방안으로는 도서관에서 전자정보실의 기능을 명확히 하는 미션과 서비스 방향을 정확히 제시하여야 하고, 사서는 전자정보실이 디지털 자료와 아날로그 자료 그리고 정보통신 기술지원이 동시에 제공되는 현대화된 레퍼런스 룸으로 인식해야 할 것이다. The domestic libraries offered users computer environment early to adapt in information age. However, the computer environment is generalized today, so it is needed to change about the role of electronic information room in this point. The author investigated use experience by 78 students who are student in library and information science. They experienced electronic information room and wrote their experience. As a result, they felt most inconvenience in information service of librarians, facilities and equipment and space. To improve the service of electronic information room, it is needed to develop the mission and service policy of electronic information room. And also the librarian must think the room as modern reference room that has digital and analog materials and information technology.

Oligonucleotide chip를 이용한 홍화자약침액(紅花子藥鍼液)이 간암세포주(肝癌細胞柱)의 유전자(遺傳子) 발현(發顯)에 미치는 영향(影響)

이경민,임성철,정태영,서정철,한상원,Lee, Kyung-min,Lim, Seong-chul,Jung, Tae-young,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2005 대한침구의학회지 Vol.22 No.3

Objective : It has long been known about the osteogenic effect of CTF-HAS on bone tissues. However, it has not been determined the effect of CTF-HAS on cancer cells. The purpose of this study is to screen the CTF-HAS mediated differentially expressed genes in cancer cells such as HepG2 hepatoma cells lines. Oligonucleotide microarray approach were employed to screen the differential expression genes. Methods : CTF-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. Cells were treated with various concentrations of CTF-HAS(0.1, 0.5, 1.5, 10, $20mg/m{\ell}$) for 24 h. Cytotoxicity was tested by MTT assay. To screen the differentially expressed genes in cancer cells, cells were treated with $1.5mg/m{\ell}$ of CTF-HAS. For oligonucleotide microarray assay, total RNA was used for gene expression analysis using oligonucleotide genechip (Human genome U133 Plus 2.0., Affimatrix Co.). ResuIts : It has no cytotoxic effects on HepG2 cells in all concentrations (0.1, 0.5, 1.5, 10, $20mg/m{\ell}$). More than twofold up-regulated genes were 19 genes. The number of more than twofold down-regulated genes was 13. Discussion : This study showed the screening of CTF-HAS mediated differentially regulated genes using combined approaches of oligonucleotide microarray. The screened genes will be used for the better understanding in therapeutic effect of CTF-HAS on cancer field.

한국인에게 플라세보 이침의 적용이 가능한가? - 단일검맹과 무작위배정법을 통한 플라세보 이침의 효과 -

이경민,이세연,김성웅,하일도,조건호,박히준,정태영,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Kim, Sung-woong,Ha, Il-do,Cho, Geon-ho,Park, Hi-joon,Jung, Tae-young,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.2

Objective : This study was designed to find out whether placebo auricular acupuncture is able to be constituted as an appropriate control group for needle insertion to Korean. Methods : We performed a randomized controlled, single-blind study(n=48) comparing subjective evaluations of needles insertion and avoidance of needles insertion. Both ears were needled concurrently, one real acupuncture(needle insertion) and the other placebo acupuncture(avoidance of needle insertion with blunt tip). Subjects then completed a questionnaire rating the intensity of five sensations in each ear, and also attempted to identity which ear received placebo and which ear received real acupuncture. Results : As for the effects of real and placebo acupuncture on each item(Warmth, Fullness, Pain, Activity, Radiating), real acupuncture was significantly warmer, fuller, more painful than placebo acupuncture. In particular, the real acupuncture only in experienced acupuncture recipients was significantly warmer, fuller, more painful than placebo acupuncture. About the ability to differentiate real and placebo acupuncture, 54.2 percent correctly identified which ear received real acupuncture and which ear received placebo acupuncture. However, the ability to differentiate real and placebo acupuncture for naive and experienced acupuncture recipients was not significantly different. Conclusions : Most of the subjects(Korean) identified which ear received placebo and which ear received real acupuncture. We found that this placebo auricular acupuncture is not able to be applied to Korean, in particular for experienced acupuncture recipients. Further study is needed for new placebo auricular acupuncture or racial difference between American.