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윤현선,조현희,조소연,이세라,신미희,정진호 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.7
Photoaging accounts for most age-related changes in skin appearance. It has been suggested that both astaxanthin, a potent antioxidant, and collagen hydrolysate can be used as antiaging modalities in photoaged skin. However, there is no clinical study using astaxanthin combined with collagen hydrolysate. We investigated the effects of using a combination of dietary astaxanthin and collagen hydrolysate supplementation on moderately photoaged skin in humans. A total of 44 healthy subjects were recruited and treated with astaxanthin (2 mg/day) combined with collagen hydrolysate (3 g/day) or placebos, which were identical in appearance and taste to the active supplementation for 12 weeks. The elasticity and hydration properties of facial skin were evaluated using noninvasive objective devices. In addition, we also evaluated the expression of procollagen type I, fibrillin-1, matrix metalloproteinase-1 (MMP-1) and -12, and ultraviolet (UV)-induced DNA damage in artificially UV-irradiated buttock skin before and after treatment. The supplement group showed significant improvements in skin elasticity and transepidermal water loss in photoaged facial skin after 12 weeks compared with the placebo group. In the supplement group, expression of procollagen type I mRNA increased and expression of MMP-1 and -12 mRNA decreased compared with those in the placebo group. In contrast, there was no significant difference in UV-induced DNA damage between groups. These results demonstrate that dietary astaxanthin combined with collagen hydrolysate can improve elasticity and barrier integrity in photoaged human facial skin, and such treatment is well tolerated.
사회경제적 배경이 청소년의 학업성취에 영향을 미치는 과정
윤현선 한국청소년학회 2006 청소년학연구 Vol.13 No.3
본 연구는 사회경제적 배경이 청소년의 학업성취에 영향을 미치는 과정을 사회적 자본이론과 가족매개모델을 통해 실증적으로 분석하고, 두 이론의 비교를 통해서 한국사회에서 사회경제적 배경이 청소년의 학업성취에 영향을 미치는 과정을 보다 잘 설명하는 모형을 규명하고자 했다. 이를 위해 한국청소년패널조사 1차년도(2003년) 원자료를 활용하여 구조방정식모형으로 분석하였다. 분석결과 사회경제적 배경이 청소년의 학업성취에 영향을 미치는데 가족내 사회적 자본과 부정적 가족관계는 중요한 매개변인으로 확인되었고, 특히 사회적 자본모형이 한국사회에서 사회경제적 배경이 청소년의 학업성취에 영향을 미치는 경로와 기제를 보다 적절히 설명하는 모형으로 밝혀졌다. 결론에서는 이러한 결과를 통해 빈곤청소년의 학업성취 향상을 위한 정책적 실천적 전략을 논의하였다. The purpose of this study is to identify how socioeconomic background affect adolescents' academic achievement. Using structural equation modeling, this study tested the equivalence of the social capital theory and the family mediation model. For it, this study uses the 2003 Korea Youth Panel Survey data. Also, through comparison of two theories, it identified the better model that explains how socioeconomic background influences adolescents' academic achievement in Korea. The major findings are as follows. The social capital model and the family mediation model showed the good fitness in analysis structural equation modeling. Family-based social capital and negative family relationships are critical mediators of the effects of socioeconomic background on adolescents' academic achievement. Social capital theory is more appropriate for identifying the process of socioeconomic background influencing adolescents' academic achievement in Korea. The findings emphasize the importance of efforts to enhance the social welfare policy support for the improvement of poor adolescent's academic achievement. This study suggests that concretely intervention strategies for poor adolescents' academic achievement need to be improved.