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      • KCI등재

        Clobazam이 가토 혈중 주정 농도에 미치는 영향에 관한 실험적 연구

        윤중석,박정수 대한신경정신의학회 1981 신경정신의학 Vol.20 No.4

        Clobazam is the first anxiolytic . drug which belongs to the class of the 1,5-rather than the 1 ,4-benzooiazepines. The structural difference beween clobazam and other benzodiazepines is that the Nin the heterocyclic ring is in positions 1 and 5 rather than in position 1 and 4. This drug possesses all the pharm acological properties of an anti-anxiety agent with out appreciable sedative and depressive side-effects. Investigators suggested that any new psychotropic drug should be tested for its . interaction with alcohol, because it might precipitate the risk situation in case of consuming alcohol concurrently. Recently it has been reported that various psychotropic agents tended to elevate the blood alcohol level. In view of these reports, the author conducted an animal experiment to investigate the effect of clobazam on the blood alcohol level in rabbits. Material and method 1. The experimental work was done on mature rabbits of both sexes, weighing about 2kg. 2. The experimental animals were divide into two groups; the control and the experimental group. 3. The control group was given alcohol alone. 4. The experim ental group was divided into 4 subgroups; a) alcohol plus clobazam, lO mg /kg of body weight daily for 5 days, h ) alcohol plus clobazam, lO mg /kg of body weight daily for 10 days. c) alcohol plus clobazam, 40mg/kg of body weight daily for 5 days. d) alcohol plu s clobazam, 40mg/kg of body weight daily for lOdays. 5. Clobazam was given orally in a single daily dose at a fixed time. The last dose was given one hour and a half before alcohol admin istration . 6. In all groups 20% ethanol solution was slowly given in a dose of 5. Omg/kg of body weight for 5 minutes by intravenous routes. 7. All of the blood specimens were obtained by cardiac puncture at 15 and 45 minutes respectively, after alcohol administration. 8. The blood alcohol level was determined by Cavett’ s method. Results 1. Alcohol plus clobazam , 10mg/kg of body 、 weight daily for 5 days. C lobazam did not change the blood alcohol level significantly at both 15 and 45 minutes after alcohol administration , (respectively, p > 0 . 05) 2. Alcohol plus clobazam, 10mg/kg of body weight daily for 10 days. In this group, there was no significant change in the blood level at both 15 and 45 minutes after alcohol administratio n ,respectively,p > 0 . 05) 3. Alcohol plus clobazam, 40mg/kg of body weight daily for 5 clays. . In th is group, there was no sig nicant change in the blood level at both 15 and 45 minutes after alcohol administration (respectively,p > 0 .0 5 ). 4. Alcohol plus clobazam, 40mg/kg of body weight daily for 10 days. In th is group, there was no significant change in the blood level at both 15 and 45 minutes after alcohol administration (respectively,p〉0 .05). Conclusion 1. Clobazam, when administered orally in a dose of lO mg /kg of body weight daily for 5 and 10 days, did not change the blood alcohol level significantly at both 15 and 45 minutes after alcohol admin istration . 2. Clobazam, when administered orally in a dose of 40mg/kg of body weight daily for 5 or 10 days, did not change the blood a lcohol level significantly a t both 15 and 45- minutes after alcohol administration.

      • 청주시 어린이 공원의 이용실태 및 이용만족도 분석

        윤중석,반영운,백종인 한국지역개발학회 2010 한국지역개발학회 학술대회 Vol.2010 No.6

        This study has intended to analyze users' behaviors and the utilijation satisfaction level of children's parks in Cheongju City. To reach this goal' this study has analyzed the behavior status and the utilijation satisfaction level of the park users through such statistical methods as frequency analysis, factor analysis. Major users of the children's park include teenagers and old people. The user have often visited the park for the purpose of rest and stability. The result of factor analysis were as follows: 1) The factors affecting the utilijation satisfaction level are classified into three factors(factor1-emotional stabilization and social function, factor2-eco-friendly and ecological education function, and factor3-base facilities and exercise support), 2) on the average, satisfaction level of factor 1 and factor3 were high, but satisfaction level of factor2 was low.

      • KCI등재

        맥주축제 이벤트품질이 축제가치, 만족 및 추천의도 간에 영향관계 검증: 부산 센텀 맥주축제를 중심으로

        윤중석 (사)한국조리학회 2018 한국조리학회지 Vol.24 No.10

        Current study explored the growth of local event in hospitality industry as one of important local society. Using a survey method, this study distribute total 400 surveys during 2018 Centum beef festival. Out of 400 participants, 365 data were used for statistical analysis without missing data and undependable respondents. The results demonstrated that the measurement of event quality is useful for testing local beer event. In addition, this study found that the four factors of event quality were significant predictors of event value. Specifically, the enviornmental factor was the most significant predictor of event value. Program, staff and convenience elements also significantly influence on event value. Furthermore, this study identied the critical relationships among event quality factors and satisfaction except enviornmental factor. These results will contribute to show more practical implication for related industry and research as well. Last this study reveal the relationships among event value, satisfaction, and recommend intention. In sum, any consumer who satisfied with the beer festival comparing their spend time and money are willing to like the event and positive recommendation to others. These study will contribute to develop similar study in hospitality industry and related academic resources in the future.

      • 통합적 기후변화 대응 도시 조성 전략 우선순위 선정

        윤중석,반영운,백종인 한국도시행정학회 2014 한국도시행정학회 학술발표대회 논문집 Vol.2014 No.2

        본 연구의 목적은 통합적 기후변화 대응을 위한 도시 조성 전략의 우선순위를 선정하는데 있다. 전략의 우선순위 결정을 위하여 도시계획, 생태도시계획, 기후변화 대응 도시계획 등의 연구를 실시한 25명의 전문가들을 대상으로 AHP 설문을 실시하였다. AHP 설문 조사 결과, 최종적으로 완화(탄소저감) 부문에서는 재생에너지, 자원순환체계확립, 대중교통활성화, 패시브디자인 등의 전략과 함께 완화(탄소흡착) 부문에서는 도시림 조성, 도시 농업도입 등이 우선순위 도시조성 전략으로 도출되었고, 적응 부문에서는 도시 수 공간 확보, 대기오염 관리, 우수 및 중수의 활용, 비점오염원 관리 등이 도출되었으며, 어울림 부문에서는 대중교통 네트워크 구축 프로그램, 에너지 저소비 도시공간 구조화 프로그램, 도시녹지 확보 프로그램, 지역사회 협력 프로그램, 주민교육, 탄소중립 생태 공동체 형성 등이 우선순위 도시조성 전략으로 도출되었다.

      • 설문조사를 통한 기후변화 적응 부문별 정책 리스트 구축

        윤중석,반영운,백종인 한국지역개발학회 2012 한국지역개발학회 세미나 논문집 Vol.2012 No.1

        The study has intended to construct the policies list in response to climate change according to adaptation sectors under local governmental level through survey analysis. To reach this goal, this study developed a pool of adaptation policies using literature review in accordance with 9 adaptation sectors, and asked 72 public officials of Chungbuk-do, who were in charge of the departments related to the adaptation sectors to respond to climate change, to answer the degree of urgency and necessity of each policy. The major six adaptation sectors include health, disaster, agriculture, forest, water management, and ecosystem. Then this study has employed statistical analysis, frequency analysis, to check statistical significance and find the frequency of each policy. Based on the statistical analysis results, this study has drawn 157 primary policies in 9 sectors.

      • 청주시 어린이 공원의 이용실태 및 이용만족도 분석

        윤중석 한국지역개발학회 2010 한국지역개발학회 세미나 논문집 Vol.2010 No.2

        This study has intended to analyze users ’ behaviors and the utilijation satisfaction level of children’s parks in Cheongju City. To reach this goal, this study has analyzed the behavior status and the utilijation satisfaction level of the park users through such statistical methods as frequency analysis, factor analysis. Major users of the children’s park include teenagers and old people. The user have often visited the park for the purpose of rest and stability. The result of factor analysis were as follows: 1) The factors affecting the utilijation satisfaction level are classified into tl끄 ee factors(factorl-emotional stabilization and social function, factor2-eco-friendly and ecological education function, and factor3-base facilities and exercise support), 2) on the average, satisfaction level of factorl and factor3 were high, but satisfaction level of factor2 was low.

      • 기후변화 적응 취약성 및 지역 특성을 고려한 지방자치단체 유형화

        윤중석(Joong Shuk, Youn),백종인(Jong In, Baek),이우균(Woo Kyun, Lee),반영운(Yong Un, Ban) 한국지역개발학회 2013 한국지역개발학회 세미나 논문집 Vol.2013 No.3

        본 연구의 목적은 기후변화 취약성 및 기후변화 관련 지역 특성을 분석하여 충청북도 12개 시/군을 유형화하는데 있다. 연구를 위해 기상 자료 및 지자체별 사회경제 현황자료를 사용하여 A1B시나리오에 근거한 기후변화 적응 6개 부문에 대한 취약성 평가를 실시하였고, 충북 지자체별 통계연보에 근거하여 기후변화 관련 현황을 검토하였으며, 2011년도 충북 시군별 업무추진계획을 검토하여 기후변화와 관련된 기 추진정책을 검토하였다. 이들을 종합적으로 분석하여 취약성 평가결과를 중심으로 기후변화 관련 지역 특성을 검토하여 충청북도 적응대책 비전을 도출하고, 12개 시/군을 유형화하였다. 연구의 결과, 충청북도 12개 지자체들은 건강 및 재난재해 부문의 기후변화 적응을 위한 ‘Safe Region’, 물 관리 부문에서의 적응을 위한 ‘Aqua Region’ 농업·산림·생태계 부문에서의 적응을 위한 ‘Vital Region’, 그리고 전 부문에서의 총체적인 기후변화 적응을 위한 ‘Extreme Region’ 등 4개 지역으로 유형화 되었다.

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