흰쥐 정상이관에서 점액선과 장액선의 분포의 특징

윤용주 ( Yong Joo Yoon ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.2

중이강의 환기, 배액 그리고 방어기능을 하고 있는 이관은 중이염의 발생에 중요한 해부조직학적 그리고 병리적 원인을 제공한다. 따라서 이관의 점막상피하 결합조직중 선조직의 점액질 분비기능은 섬모기능과 함께 외계에 대한 국소방어의 일차적 역할을 담당하여 흡입된 이물질이나 세균의 정화작용을 하며 기계적 자극이나 독성 자극에 대하여 상피를 보호하고 수분의 손실을 막아준다. 이런 선조직의 조직화학적 연구는 중이염의 연구에 있어 매우 중요하며 앞으로 중이염에 대한 병인을 규명하는 연구가 될 수 있을 것으로 생각된다. 본 연구는 중이염 발생이 인간과 비슷한 흰쥐에서 10% 중성 formalin으로 관류고정한 후 이관을 포함한 중이 일부를 얻어 탈회, 파라핀봉입후 5 цm 두께의 절편을 얻어 alcian blue / periodic acid-Schiff (AB-PAS)로 염색하여 광학 현미경으로 관찰하였다. 1) 흰쥐 이관의 인두구쪽이 고실구쪽보다 많은 선들이 존재함을 알 수 있었고 관강 가까이에 장액선들이 분포되어 있고 상부에서도 존재하지만 주로 하부에서 많은 선세포들이 관찰되었다. 2) 흰쥐 이관의 연골부의 관강은 세극상이며 선조직은 주로 내측에서 관찰되어지고 특히 장액선은 주로 혈관주위에 분포해있고 외측으로는 선조직은 보이지 않고 이관주위의 결합조직으로 차지하고 있었다. 3) 이관에서 중이로의 이행부위에는 내, 외 양측으로 선조직을 거의 관찰할 수 없었다. The tubotympanum is protected by several complex mechanisms. Seromucinous glands of the eustachian tube secrete essential macromolecules in the mucociliary function and also produce antibacterial-antiviral enzymes. The presence of secretory cells in the tubotympanum suggests the presence of chemical defense system in addition to the mucociliary mechanincal defense system. The establishment for distribution of secretory cells in normal Eustachian tube, therefore is an important step forward in the elucudiation of the tubotympanic defense mechanisms. The glands of the Eustachian tube were tubuloacinar mixed glands composed of serous demilunes and mucous acini. AB-PAS staining clearly distinguishs the serous from the mucous cells. The specimens obtained from rat Eustachian tube were stained with alcian blue-periodic acid Schiff and studied by light microscopy. The glands were present in both the medial and lateral lamina of the eustachain tube. The density of the glands was significantly lower in the roof than in the floor of the Eustachian tube and was highest in the pharyngeal portion. Glands became less densely distributed toward the tympanic portion. The tympanic portion and middle ear submucosa seldom have glands. These findings suggest that the lower portion of the pharyngeal tube is related to the clearance and biological protection of the tube.

의류 패션산업에서 순한글과 외래어 용어에 대한 감성 비교

윤용주 ( Yong Ju Yoon ),나영주 ( Young Joo Na ) 한국감성과학회 2015 감성과학 Vol.18 No.1

본 연구는 패션산업에서 상품라벨과 패션용어의 형태, 즉 한글과 외래어, 외국어 등 표기 종류에 따라 소비자의 감성이 어떻게 다르게 나타나는지 분석한 것이다. 20대 소비자 200명을 대상으로 패션아이템 1종에 대한 라벨 1종과 3종 패션용어에 대하여 설문조사를 실시하였는데 외래어 영어표기, 외래어 한글표기, 순한글표기 등 3가지 형태에 대해 15개 형용사로 구성된 감성 척도를 이용하여 감성을 측정하였고 또한 선호도와 상품에 대한 예상가격을 질문하였다. 결과로는 소비자들은 라벨에서 한글보다 외래어를 선호하였으며 외래어 라벨 중에서도 한글표기보다 영어표기를 선호하였다. 외래어 라벨을 볼 때 소비자들은 패션 제품이 더 ‘긍정적이고 세련되고 화려하며 우아하다’고 평가하고 있었으며 또 상품의 가격을 더 높은 것으로 예상하였다. 즉 외래어 영어표기 라벨이 모든 평가에서 가장 높은 점수를 받았고, 외래어 한글표기가 다음 순이었으며, 순한글 라벨은 가장 낮은 평가를 받았다. 소비자들은 자신의 유행 몰입도에 따라서 감성평가를 부분적으로 다르게 하고 있는 것으로 나타났다. 즉 유행 몰입도가 높은 소비자들은 낮은 소비자보다 외래어를 볼때 ‘세련된 우아한 화려한’ 등에 대해서 더 높게 평가하고 있었다. 또한 유행몰입도가 높은 소비자들은 낮은 소비자보다 순한글표기 라벨을 볼 때 ‘친근한, 안정된’ 등에 대해서 더 높게 또는 외래어와 유사하게 평가하고 있었다. The purpose of this study is to analyze the emotion and sensibility of fashion words in terms of words types, such as loanword and Korean words, Hangul in fashion product label and fashion manufacturing industry. We surveyed 200 persons in their 20s using the questionnaire on the stimulus of product tag label and fashion words with 15 adjectives. Based on daily usage of foreign words in fashion market, we selected 1 item label in 3 forms: 1) Hangul label written in loan words 2) Label written in English and 3) Label written in Hangul and 3 fashion words in 2 forms 1) loanword and 2) Hangul. And the label types and fashion words were analyzed and investigated in terms of consumer``s sensibility, preferences and estimated product price. The results are following: consumers preferred loanword label than Hangul label, and they preferred loanword in English than that in Korean. They evaluated loanword more positively, such as refinement, gorgeous and elegant, etc. and estimated the product price of loanword label as higher. But in the sensibility of ``familiar`` and ``stability``, Hangul label was not significantly different to loanword written in Hangul. That is, label written in English is the highest in all the evaluation, and loanword label written in Hangul is next, and Hangul label showed the lowest result. Consumers showed the evaluation differently between loanwords and Hangul according to their degree in fashion involvement. Consumers of high fashion involvement evaluated the sensibilities of ``refinement``, ``elegant``, and ``gorgeous`` of loanwords as higher, whereas they had tendency to evaluate the sensibilities of ``familiar`` and ``stability`` of Hangul as higher or similar.

타액선종양의 임상적 고찰

양윤수(Yoon Soo Yang),김범규(Beom Kyu Kim),김연우(Yeon Woo Kim),권삼현(Sam Hyun Kwon),윤용주(Yong Joo Yoon),홍기환(Ki Hwan Hong) 대한두경부종양학회 2004 대한두경부 종양학회지 Vol.20 No.1

Background and Objectives: Salivary gland tumors are relatively rare and constitute 3% to 4% of all head and neck neoplasms. Their relative infrequency, inconsistent classification, and highly variable biologic behavior make some difficulty, but some general features can be drawn regarding the incidence, pathology, and pattern of behavior of the various benign and malignant tumors of salivary glands. The present study aims to provide a clinical characteristics of salivary gland tumors. Materials and Methods: We analyzed retrospectively clinical features of the 138 patients who were treated surgically at Chonbuk National University Hospital from 1992 through 2002. Results: We found 107 benign and 31 malignant tumors. Among the patients, 58 were males and 80 were females. The most common age group was the fifties. The most common site of both benign and malignant was parotid gland in major salivary glands and palatal region in minor salivary glands. The most common presenting symptom was palpable mass in both benign and malignant tumor. Histopathologically, the most common type was pleomorphic adenoma in benign tumor and mucoepidermoid carcinoma in malignant tumor. All cases were treated surgically and the most common postoperative complications was transient facial nerve weakness. Conclusion: 138 cases of salivary gland tumors were presented with respect to their clinical features.

성대낭종의 임상적 특성

조영주,양윤수,윤용주,권삼현,홍기환,Cho, Young-Ju,Yang, Yoon-Su,Yoon, Yong-Joo,Kwon, Sam-Hyun,Hong, Ki-Hwan 대한후두음성언어의학회 2009 대한후두음성언어의학회지 Vol.20 No.1

본 교실에서 1988년 1월부터 2007년 12월까지 시행했던 후두미세수술 4201례중 수술 후 성대낭종으로 확진된 212례를 대상으로 다음과 같은 결과를 얻었다. 1) 전체 후두미세수술 4,201례 중 성대낭종이 차지하는 비율은 212례로 5.04%였다. 2) 성대낭종 212례 중 유표피낭종은 56례(26.4%), 저류낭종이 156례(73.6%)를 차지하여 미미하지만 지속적인 저류낭종의 증가 추세를 보이고 있었다. 3) 성별분포는 212례의 성대낭종 중 여성이 135례(63.7%), 남성이 77례(36.3%)로 여성에 호발하였으며 최근에는 남녀 비율의 차이가 감소해가는 추세를 보이고 있었다. 4) 이학적 검사소견으로서 유피낭종은 술 전 이학적 검사상 56례 중 불과 33례(58.9%)에서 낭종을 의심할 수 있었고 저류낭종은 술 전 낭종을 의심할 수 있었던 경우가 156례중 70례로 44.9%에 불과해 성대낭종은 술 전 진단이 용이하지 않았다. 5) 병리조직학적 검사상 유표피낭종 내부에 PAS 음성인 케라틴과 콜레스테롤양(cholesterol-like)물질이 중층 편평상피로 구성된 막에 둘러 싸여 있는 양상을 보였고 저류낭종은 내부에 PAS 양성인 점액분비물을 포함하고 있는 원주 또는 입방세포로 구성된 막으로 이루어져 있었다. 6) 애성 발생과 관련된 유발 요인으로는 성대과용 또는 음성남용과 관련된 경우가 212례 중 80례(37.7%)로 성대과용이 주요한 유발인자로 생각된다. 7) 발병부위는 대부분 막성유리연의 중간부 및 전방부 1/3에서 발생하였고 수술 결과는 저류낭종 150례 중 54례(36.0%)에서만 낭종의 파열 없이 완전제거가 가능하였으며 유표피낭종 54례 중에서는 41례(75.9%)에서 낭종의 파열 없이 완전제거가 가능했던 것으로 나타나 저류낭종이 유표피낭종에 비해 낭종을 파열시키지 않고 완전히 제거하는 것이 더욱 어려움을 알 수 있었다. 따라서 저류낭종의 경우 낭종의 절제가 어려운 경우 수술방법으로 조대술(marsupialization)을 시행하는 것도 의미가 있을 것으로 사료된다. Background and Objectives: Intracordal cysts may occur secondary to voice abuse and overuse or may be secondary to a remnant of epithelium trapped within the lamina propria. They may occur spontaneously or may be associated with poor vocal hygiene. As the cyst enlarges it can start to significantly affect the vibratory region of the vocal fold. With the advancement of the microsurgical technique and the laryngeal stroboscopy, correct diagnosis of intracordal cyst have been increased. The aims of this study is to review the important clinical characteristics of the intracordal cyst. Materials and Methods: In the present study, 212 cases of the intracordal cysts were treated by the microsurgical technique. These lesions were diagnosed before the operation with indirect laryngoscopy, laryngeal endoscopy, laryngeal stroboscopy and confirmed with the findings observed during operations and the results of the biopsies. Results : The intracordal cysts were 212 cases in the 4,20 I patients who underwent laryngeal microsurgery (5.04%). Ductal cysts were 156 cases and epidermoid cysts were 56 cases. The lesions are more frequent in women and anterior third of true vocal cord is more frequently involved site. With the preoperative laryngoscopic examination, the intracordal cysts were mostly misdiagnosed as other disease of the vocal cord such as vocal polyps or nodules. And main cause of intracordal cysts was thought of vocal abuse. From view of the surgical approach, Ductal cysts was difficult to remove completely than epidermoid cyst without cystic wall rupture. Conclusion : Intracordal cysts are very similar to the other mucosal disorders of the vocal cord and it may be misdiagnosed as vocal polyps or nodules, frequently. Therefore careful preoperative examinations for the vocal cord lesions with stroboscopy and other endoscopic instruments are important part of the correct diagnosis. An ideal treatment is enucleation of the cysts without rupture of the cystic wall or injury of the lamina propria. And marsupialization is meaningful to ductal cyst that cannot be enucleated completely.

소이증 환자에서 자가 흉연골을 이용한 이개 성형술 4례

윤용주,김영기,양경무 의과학연구소 1990 全北醫大論文集 Vol.14 No.3

The term microtia indicates various degree of hypoplasia of the external ear associated with absence (atresia) of the external meatus external auditory canal. Microtia may be present as an auricular deformity only, accompanied by normal growth and development of the entire face, or it may be component of hemifacial or bilateral facial microsomia. Numerous material have been employed in oloplasty, including homogenous and hetergenous cartilage have proven as the most successful long-term material. Recently we had successful result of four cases of auricle reconstruction with autogenous rib cartilage. We report there cases with review of literature.

흰쥐 고막과 이관에서 비만세포의 분포

윤용주,정우철,정경수 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.12

흰쥐 이관과 고막에서 Alpha 1-antitrypsin의 면역조직화학적 국소화에 대한 연구

윤용주,정우철,김영기 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.3

수평반고리관 양성 발작성 두위현기증

김영기,윤용주,김인 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

성문암의 방사선 치료

김종수,권형철,윤용주 의과학연구소 1990 全北醫大論文集 Vol.14 No.2

A detailed retrospective analysis of the results of treatment of glottic cancer is presented. Twelve patients were treated by curative radiation therapy at the Department of Therapeutic Radiology in Chonbuk National University Hospital between 1986 and 1989. All Patients had squamous cell cardinoma, half of them had well differentiated type. A month after radiation therapy, the complete remission rate was 90% in early glottic cancer and partical remission rate was 100% in advanced glottic cancer. The use of voice after radiation therapy and surgery is also discussed.

전신 마취시 아산화질소 투여 중단후 중이 내압의 변동

송희선,이상귀,윤용주,홍기환,최현규,신감진,권삼현 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.6

N₂O can diffuse in and/or out the middle ear cavities and it may alter the middle ear pres-sure. This study was performed to investigate the effect of N₂O discontinuation on the changes in middle ear pressure during general endotracheal anesthesia. We measured middle ear pres-sures and end-tidal NO concentrations at preanesthesia, immediately after N₂O discontinuation and then at every five minutes for 60 minutes under either halothane or enflurane an- esthesia in two groups(group 1=50% administration of N₂O in O₂; group 2=60% administration of N₂O in O₂). The middle ear pressures after N₂O discontinuation decreased slowly but they did not returned to the preanesthetic value in both groups. The end-tidal N₂O concentrations decreased rapidly until five minutes and then they decresed slowly to the zero leve1 until 30 minutes after N₂O discontinuation in both groups. The expected time of the middle ear pres-sure of preanesthesia value was 89.4 minutes in group 1 and 80.9 minutes in group 2 respectively. The middle ear pressure do not return to the level of preanesthesia at 60 minutes after N₂O discontinuation while the end-tidal N₂O concentration decrease to the zero level via 30 minutes after its discontinuation. Thus it is recommended that N₂O administration should be discontinued at least 30 minutes before an application of tympanic membrane patch on the ear drum and N₂O is carefully administered in patients with middle ear and/or upper airway disesses.