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Epidemilogy of Respiratory Distress Syndrome
홍성봉(SB Hong),박용균(YK Park),이규완(KW Lee),유동화(DH Yoo) 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.7
1980년 1월 1일부터 1984년 12월 31일까지 고려대학교 의과대학 혜화병원 산부인과에서 최근에 분만한 총 4,879예중 호흡곤란증후군이 발생한 46예를 대상으로하여 아래와 같은 결론을 얻었다 1 발생빈도는 0 94%이었다 2 성별로는 남아가 80 4%로 많았다 3 체중별로 보면 2500gm미만에서 67 5%가 발생하였다 4 제태기간에 따른 빈도롤 보면, 37주이하에서 69 5%의 높은 빈도를 보였고, 동기간의 전체 분만에서 보면, 정상 제태기간에서는 0 33%만이 발생한 반면 조산아의 경우 337예중 30예인 8 90%에서 호흡곤란증후군이 발생하였다 5 산모의 연령별로 보면, 동기간의 전체분만중 30∼34세군이 2 17%, 35∼39세군이 2 08%의 높은 빈도를 보였고, 25∼29세군은 0 93%의 빈도를 보였다 6 3회 경산에서 2 35%, 1회 경산에서 1 05%로 초산의 0 90%보다 높았다 7 제왕절개술에서 1 24%로 질식분만의 0 83%보다 높은 빈도를 보였다 제왕절개술의 경우 그 적응증은 uterine hypoperfusion이 52 9%로 반수이상을 차지했다 8 쌍태아의 경우는 17 4%이고, 제2아에서 50 0%로 높은 빈도를 보였으나 통계학적 의의는 없었다 9 계절별로 보면 가을, 봄이 34 8%, 30 4%로 여름(13 0%)보다 높은 빈도를 보였다 10 호흡곤란증후군에서는 89 1%로 신생아가 사망했고, 그 사망시기는 2일이내가 87 8%를 차지했다 This is a review of 46 cases of Respiratory Distress Syndrome in 4879 deliveries at Hae Wha General Hospital, Korea University from January 1, 1980 to December 31, 1984 The results were summerized as follows: 1 Overall incidence of RDS was 0 94% 2 The incidence of RDS in male baby was remarkably higher than that of female baby (80 4% in male baby & 19 6% in female baby ) 3 The rate of RDS in low birth weight (under 2500Gm)was 67 5% 4 The rate of RDS in preterm (before 37wks) was 69 5% The overall incidence of RDS in preterm(8 90%)was higher than that of term bady (0 33%) 5 The overall incidence of RDS by maternal age was 2 17% in the age group of 30-34 years old, 2 08% in the age group 35-39 years old, and 0 93% in the age group of 25-29 years old 6 The incidence of RDS in para 3 (2 23%) and para 1 (1 05%) women was higher than that of primiparous(0 90%) 7 The incidence of RDS was higher in C/S (1 24%) than vaginal delivery (0 83%), the most common indication for C/S was uterine hypoperfusion, i e placenta previa and abruptio placenta (41 1%, 5 9%) and fetal distress (5 9%) 8 The rate of twin delivery in RDS was 17 4% and second baby was prevalent (50 0%), but there was no statistical significance 9 The incidence was higher in autumn and spring (34 8%, 30 4%) than summer season (13 0%) 10 The mortality was 89 1% & among these 87 8% were died in first 2 days after birth
구병삼,유동화,이규완,나중열,홍성봉,배인하,Ku, Pyong-Sahm,Yoo, Dong-Wha,Lee, Kyu-Won,Rha, Joong-Yul,Hong, Sung-Bong,Bae, In-Ha 대한생식의학회 1986 Clinical and Experimental Reproductive Medicine Vol.13 No.2
We have reviewed 59 cases of patients amoung 65 cases who underwent IVF and ET with reasonable indications irom 1984 and the results as follows. 1. Major indications for IVF and ET were tubal factor (40.7%), unexplained infertility (25.4%), endometriosis (15.3%), failed AID and AIH (10.1 %), and sperm abnormality (8.5%). 2. For superovulation of human oocytes, l00mg of clomiphene citrate and 75 IU of HMG used. The monitoring of oocyte maturation was bone by ultrasound examination and serum 17-${\beta}$ estradiol, LH values. The peak $E_2$ value was 956.36${\pm}$702.13 pg/ml. 3. The oocytes were obtained by laparoscopy 24-36 hours after the injection of HCG. 4. The mean numbers of follicles at laparoscopy was 3.06 and the successful rate of laparoscopy was 79.7%. 5. And 165 follicles were aspirated from which 98 oocytes were recovered, 59.4% of all follicles had at least one oocyte aspirated. 21.4% of the eggs were mature, 52.0% were moderate, 26.5%. were immature. 6. 67.3% of oocytes were cleaved and were transferred at 4-6 cell stages. 7. Four pregnancies including one chemical pregnancy and one spontaneous abortion were established by ${\beta}$-subunit, u-hCG and ultrasound examinations.